| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hao Ma, Songlin Liu, Yawen Liu, Jinyu Zhu, Xiao Xia Han, Yukihiro Ozaki, Bing Zha. In-situ fingerprinting phosphorylated proteins via surface-enhanced Raman spectroscopy: Single-site discrimination of Tau biomarkers in Alzheimer's disease. Biosensors & bioelectronics. vol 171. 2021-05-14. PMID:33113381. |
in-situ fingerprinting phosphorylated proteins via surface-enhanced raman spectroscopy: single-site discrimination of tau biomarkers in alzheimer's disease. |
2021-05-14 |
2023-08-13 |
Not clear |
| Krystal K Laing, Sabrina Simoes, Gloria P Baena-Caldas, Patrick J Lao, Milankumar Kothiya, Kay C Igwe, Anthony G Chesebro, Alexander L Houck, Lina Pedraza, A Iván Hernández, Jie Li, Molly E Zimmerman, José A Luchsinger, Frank C Barone, Herman Moreno, Adam M Brickma. Cerebrovascular disease promotes tau pathology in Alzheimer's disease. Brain communications. vol 2. issue 2. 2021-05-14. PMID:33215083. |
cerebrovascular disease promotes tau pathology in alzheimer's disease. |
2021-05-14 |
2023-08-13 |
mouse |
| Krystal K Laing, Sabrina Simoes, Gloria P Baena-Caldas, Patrick J Lao, Milankumar Kothiya, Kay C Igwe, Anthony G Chesebro, Alexander L Houck, Lina Pedraza, A Iván Hernández, Jie Li, Molly E Zimmerman, José A Luchsinger, Frank C Barone, Herman Moreno, Adam M Brickma. Cerebrovascular disease promotes tau pathology in Alzheimer's disease. Brain communications. vol 2. issue 2. 2021-05-14. PMID:33215083. |
the purpose of this study was to examine the association between white matter hyperintensities and plasma levels of tau and to determine if white matter hyperintensities and tau levels interact to predict alzheimer's disease diagnosis. |
2021-05-14 |
2023-08-13 |
mouse |
| Stephanie L Peak, Liam Gracia, Gabriella Lora, Umesh K Jinwa. Hsp90-interacting Co-chaperones and their Family Proteins in Tau Regulation: Introducing a Novel Role for Cdc37L1. Neuroscience. vol 453. 2021-05-14. PMID:33246057. |
in particular, in alzheimer's disease (ad) or ad-like conditions, tau becomes hyperphosphorylated and forms toxic aggregates inside the cell. |
2021-05-14 |
2023-08-13 |
Not clear |
| M Bell, S Bachmann, J Klimek, F Langerscheidt, H Zempe. Axonal TAU Sorting Requires the C-terminus of TAU but is Independent of ANKG and TRIM46 Enrichment at the AIS. Neuroscience. vol 461. 2021-05-14. PMID:33556457. |
somatodendritic missorting of the axonal protein tau is a hallmark of alzheimer's disease and related tauopathies. |
2021-05-14 |
2023-08-13 |
mouse |
| Heng Sun, Yan Zhong, Xiandi Zhu, Hongwei Liao, Jiyoung Lee, Ying Chen, Lijuan Ma, Jiafeng Ren, Meng Zhao, Mengjiao Tu, Fangyuan Li, Hong Zhang, Mei Tian, Daishun Lin. A Tauopathy-Homing and Autophagy-Activating Nanoassembly for Specific Clearance of Pathogenic Tau in Alzheimer's Disease. ACS nano. vol 15. issue 3. 2021-05-14. PMID:33683854. |
a tauopathy-homing and autophagy-activating nanoassembly for specific clearance of pathogenic tau in alzheimer's disease. |
2021-05-14 |
2023-08-13 |
rat |
| Heng Sun, Yan Zhong, Xiandi Zhu, Hongwei Liao, Jiyoung Lee, Ying Chen, Lijuan Ma, Jiafeng Ren, Meng Zhao, Mengjiao Tu, Fangyuan Li, Hong Zhang, Mei Tian, Daishun Lin. A Tauopathy-Homing and Autophagy-Activating Nanoassembly for Specific Clearance of Pathogenic Tau in Alzheimer's Disease. ACS nano. vol 15. issue 3. 2021-05-14. PMID:33683854. |
the hyperphosphorylated and aggregated tau accumulation represents a significant pathological hallmark of tauopathies including alzheimer's disease (ad), which is highly associated with defective autophagy in neuronal cells. |
2021-05-14 |
2023-08-13 |
rat |
| Nalini V Gorantla, Rashmi Das, Fayaj A Mulani, Hirekodathakallu V Thulasiram, Subashchandrabose Chinnathamb. Neem Derivatives Inhibits Tau Aggregation. Journal of Alzheimer's disease reports. vol 3. issue 1. 2021-05-13. PMID:31259310. |
alzheimer's disease pathology triggers several modifications in tau, which causes it to lose its affinity towards microtubule, thus, leading to microtubule disassembly and loss of axonal integrity. |
2021-05-13 |
2023-08-13 |
Not clear |
| Kelly Ceyzériat, Benjamin B Tournier, Philippe Millet, Giovanni B Frisoni, Valentina Garibotto, Thomas Zill. Low-Dose Radiation Therapy: A New Treatment Strategy for Alzheimer's Disease? Journal of Alzheimer's disease : JAD. vol 74. issue 2. 2021-05-13. PMID:32039848. |
alzheimer's disease (ad) is a neurodegenerative disease characterized by extracellular amyloid-β (aβ) peptide aggregates, forming amyloid plaques, and intracellular deposits of phosphorylated tau. |
2021-05-13 |
2023-08-13 |
Not clear |
| Claudio Liguori, Matteo Spanetta, Francesca Izzi, Flaminia Franchini, Marzia Nuccetelli, Giulia Maria Sancesario, Simona Di Santo, Sergio Bernardini, Nicola Biagio Mercuri, Fabio Placid. Sleep-Wake Cycle in Alzheimer's Disease Is Associated with Tau Pathology and Orexin Dysregulation. Journal of Alzheimer's disease : JAD. vol 74. issue 2. 2021-05-13. PMID:32065791. |
sleep-wake cycle in alzheimer's disease is associated with tau pathology and orexin dysregulation. |
2021-05-13 |
2023-08-13 |
Not clear |
| Yanli Jiang, Longfei Li, Chun-Ling Dai, Ranran Zhou, Cheng-Xin Gong, Khalid Iqbal, Jin-Hua Gu, Fei Li. Effect of Peripheral Insulin Administration on Phosphorylation of Tau in the Brain. Journal of Alzheimer's disease : JAD. vol 75. issue 4. 2021-05-13. PMID:32417781. |
abnormally hyperphosphorylated tau is the major protein of neurofibrillary tangles in alzheimer's disease. |
2021-05-13 |
2023-08-13 |
Not clear |
| Erratum to: Alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. Brain : a journal of neurology. vol 144. issue 4. 2021-05-13. PMID:33437996. |
erratum to: alzheimer's disease brain-derived extracellular vesicles spread tau pathology in interneurons. |
2021-05-13 |
2023-08-13 |
Not clear |
| Christian Humpe. Intranasal Delivery of Collagen-Loaded Neprilysin Clears Beta-Amyloid Plaques in a Transgenic Alzheimer Mouse Model. Frontiers in aging neuroscience. vol 13. 2021-05-13. PMID:33967739. |
alzheimer's disease (ad) is pathologically characterized by extracellular beta-amyloid (aβ) plaques and intraneuronal tau tangles in the brain. |
2021-05-13 |
2023-08-13 |
mouse |
| Rik Ossenkoppele, Oskar Hansso. Towards clinical application of tau PET tracers for diagnosing dementia due to Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-05-13. PMID:33984177. |
towards clinical application of tau pet tracers for diagnosing dementia due to alzheimer's disease. |
2021-05-13 |
2023-08-13 |
Not clear |
| Rik Ossenkoppele, Oskar Hansso. Towards clinical application of tau PET tracers for diagnosing dementia due to Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2021-05-13. PMID:33984177. |
the recent development of several tau positron emission tomography (pet) tracers represents a major milestone for the alzheimer's disease (ad) field. |
2021-05-13 |
2023-08-13 |
Not clear |
| Ryszard Pluta, Liang Ouyang, Sławomir Januszewski, Yang Li, Stanisław J Czuczwa. Participation of Amyloid and Tau Protein in Post-Ischemic Neurodegeneration of the Hippocampus of a Nature Identical to Alzheimer's Disease. International journal of molecular sciences. vol 22. issue 5. 2021-05-12. PMID:33671097. |
participation of amyloid and tau protein in post-ischemic neurodegeneration of the hippocampus of a nature identical to alzheimer's disease. |
2021-05-12 |
2023-08-13 |
Not clear |
| Connor M Wander, Jui-Heng Tseng, Sheng Song, Heba A Al Housseiny, Dalton S Tart, Aditi Ajit, Yen-Yu Ian Shih, Rebecca Lobrovich, Juan Song, Rick B Meeker, David J Irwin, Todd J Cohe. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. vol 23. issue 7. 2021-05-11. PMID:32585593. |
the microtubule-associated tau protein forms pathological inclusions that accumulate in an age-dependent manner in tauopathies including alzheimer's disease (ad). |
2021-05-11 |
2023-08-13 |
mouse |
| Allal Boutajangout, Wei Zhang, Justin Kim, Wed Ali Abdali, Frances Prelli, Thomas Wisniewsk. Passive Immunization With a Novel Monoclonal Anti-PrP Antibody TW1 in an Alzheimer's Mouse Model With Tau Pathology. Frontiers in aging neuroscience. vol 13. 2021-05-11. PMID:33716717. |
passive immunization with a novel monoclonal anti-prp antibody tw1 in an alzheimer's mouse model with tau pathology. |
2021-05-11 |
2023-08-13 |
mouse |
| Ruihua Sun, Huayuan Wang, Yingying Shi, Zhikun Sun, Haisong Jiang, Jiewen Zhan. Changes in the Morphology, Number, and Pathological Protein Levels of Plasma Exosomes May Help Diagnose Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884461. |
recent studies have shown that exosomes contain both amyloid-β (aβ) and tau proteins and have a controversial role in the alzheimer's disease (ad) process. |
2021-05-10 |
2023-08-13 |
Not clear |
| Yanying Liu, Hongmin Wan. Modeling Sporadic Alzheimer's Disease by Efficient Direct Reprogramming of the Elderly Derived Disease Dermal Fibroblasts into Neural Stem Cells. Journal of Alzheimer's disease : JAD. vol 73. issue 3. 2021-05-10. PMID:31884463. |
alzheimer's disease (ad) is a devastating neurodegenerative disorder, neuropathologically characterized by hyperphosphorylation of tau and formation of amyloid plaques. |
2021-05-10 |
2023-08-13 |
Not clear |