| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Simah Mohammadi, Hashem Rafii-Tabar, Pezhman Sasanpou. A modeling study of the effect of an alternating magnetic field on magnetite nanoparticles in proximity of the neuronal microtubules: A proposed mechanism for detachment of tau proteins. Computer methods and programs in biomedicine. vol 222. 2022-06-23. PMID:35738092. |
it is known that the disintegration of microtubules in neurons occurs in response to the phosphorylation of the tau proteins that promotes the structural instability of the microtubules, as one of the factors underlying the onset of alzheimer's disease (ad). |
2022-06-23 |
2023-08-14 |
Not clear |
| Shu-Qin Cao, Yahyah Aman, Evandro F Fang, Tewin Tencomna. P. edulis Extract Protects Against Amyloid-β Toxicity in Alzheimer's Disease Models Through Maintenance of Mitochondrial Homeostasis via the FOXO3/DAF-16 Pathway. Molecular neurobiology. 2022-06-23. PMID:35739408. |
alzheimer's disease (ad) is a common and devastating disease characterized by pathological aggregations of beta-amyloid (aβ) plaques extracellularly, and tau tangles intracellularly. |
2022-06-23 |
2023-08-14 |
caenorhabditis_elegans |
| S Tok, H Maurin, C Delay, D Crauwels, N V Manyakov, W Van Der Elst, D Moechars, W H I M Drinkenbur. Pathological and neurophysiological outcomes of seeding human-derived tau pathology in the APP-KI NL-G-F and NL-NL mouse models of Alzheimer's Disease. Acta neuropathologica communications. vol 10. issue 1. 2022-06-23. PMID:35739575. |
pathological and neurophysiological outcomes of seeding human-derived tau pathology in the app-ki nl-g-f and nl-nl mouse models of alzheimer's disease. |
2022-06-23 |
2023-08-14 |
mouse |
| Mengmeng Zheng, Jiangyu Yan, Wenjuan Hao, Yuan Ren, Ming Zhou, Yunzhi Wang, Kai Wan. Worsening hearing was associated with higher β-amyloid and tau burden in age-related hearing loss. Scientific reports. vol 12. issue 1. 2022-06-21. PMID:35729211. |
β-amyloid plaques and tau accumulation in brain are hallmarks pathologic feature of alzheimer's disease (ad), which is a leading cause resulting in dementia. |
2022-06-21 |
2023-08-14 |
Not clear |
| Abdullah Al Bashit, Prakash Nepal, Theresa Connors, Derek H Oakley, Bradley T Hyman, Lin Yang, Lee Makowsk. Mapping the Spatial Distribution of Fibrillar Polymorphs in Human Brain Tissue. Frontiers in neuroscience. vol 16. 2022-06-20. PMID:35720706. |
alzheimer's disease (ad) is a neurodegenerative disorder defined by the progressive formation and spread of fibrillar aggregates of aβ peptide and tau protein. |
2022-06-20 |
2023-08-14 |
human |
| Xing Fan, Liye Xia, Zheng Zhou, Yanyan Qiu, Chenhao Zhao, Xiaomin Yin, Wei Qia. Tau Acts in Concert With Kinase/Phosphatase Underlying Synaptic Dysfunction. Frontiers in aging neuroscience. vol 14. 2022-06-17. PMID:35711910. |
alzheimer's disease (ad) is characterized by two pathological features: neurofibrillary tangles (nfts), formed by microtubule-associated protein tau, and abnormal accumulation of amyloid-β (aβ). |
2022-06-17 |
2023-08-14 |
Not clear |
| Kristian F Odfalk, Kevin F Bieniek, Sarah C Hop. Microglia: Friend and Foe in Tauopathy. Progress in neurobiology. 2022-06-17. PMID:35714860. |
the consistent spatiotemporal progression of tau pathology in alzheimer's disease (ad) led to the hypothesis that tau aggregates spread in the brain via bioactive tau "seeds" underlying advancing disease course. |
2022-06-17 |
2023-08-14 |
Not clear |
| Vrinda Kalia, Megan M Niedzwiecki, Joshua M Bradner, Fion K Lau, Faith L Anderson, Meghan L Bucher, Katherine E Manz, Alexa Puri Schlotter, Zoe Coates Fuentes, Kurt D Pennell, Martin Picard, Douglas I Walker, William T Hu, Dean P Jones, Gary W Mille. Cross-species metabolomic analysis of tau- and DDT-related toxicity. PNAS nexus. vol 1. issue 2. 2022-06-16. PMID:35707205. |
exposure to the pesticide dichlorodiphenyltrichloroethane (ddt) has been associated with increased risk of alzheimer's disease (ad), a disease also associated with hyperphosphorylated tau (p-tau) protein aggregation. |
2022-06-16 |
2023-08-14 |
Not clear |
| Nicola Spotorno, Chloé Najac, Erik Stomrud, Niklas Mattsson-Carlgren, Sebastian Palmqvist, Danielle van Westen, Itamar Ronen, Oskar Hansso. Astrocytic function is associated with both amyloid-β and tau pathology in non-demented Brain communications. vol 4. issue 3. 2022-06-15. PMID:35702728. |
astrocytic function is associated with both amyloid-β and tau pathology in non-demented a growing body of evidence suggests that astrocytes play a major role in the pathophysiology of alzheimer's disease. |
2022-06-15 |
2023-08-14 |
Not clear |
| Gemma Salvadó, Mahnaz Shekari, Carles Falcon, Grégory Operto, Marta Milà-Alomà, Gonzalo Sánchez-Benavides, Raffaele Cacciaglia, Eider Arenaza-Urquijo, Aida Niñerola-Baizán, Andrés Perissinotti, Carolina Minguillon, Karine Fauria, Gwendlyn Kollmorgen, Ivonne Suridjan, José Luis Molinuevo, Henrik Zetterberg, Kaj Blennow, Marc Suárez-Calvet, Juan Domingo Gisper. Brain alterations in the early Alzheimer's continuum with amyloid-β, tau, glial and neurodegeneration CSF markers. Brain communications. vol 4. issue 3. 2022-06-15. PMID:35702732. |
brain alterations in the early alzheimer's continuum with amyloid-β, tau, glial and neurodegeneration csf markers. |
2022-06-15 |
2023-08-14 |
Not clear |
| Amelia Hicks, Jennie L Ponsford, Gershon Spitz, Vincent Dore, Natasha Krishnadas, Caroline Roberts, Christopher C Row. Amyloid- and Tau Imaging in Chronic Traumatic Brain Injury: A Cross-sectional Study. Neurology. 2022-06-15. PMID:35705503. |
there is evidence of elevated amyloid-β and tau, the pathological hallmarks of alzheimer's disease, immediately following tbi. |
2022-06-15 |
2023-08-14 |
Not clear |
| Ning Yan, Xiao-Long Shi, Long-Qian Tang, De-Feng Wang, Xun Li, Chao Liu, Zhao-Peng Li. Synthesis and biological evaluation of thieno[3,2- Journal of enzyme inhibition and medicinal chemistry. vol 37. issue 1. 2022-06-14. PMID:35698879. |
synthesis and biological evaluation of thieno[3,2- glycogen synthase kinase 3β (gsk-3β) catalyses the hyperphosphorylation of tau protein in the alzheimer's disease (ad) pathology. |
2022-06-14 |
2023-08-14 |
Not clear |
| Amy N Zwierzchowski-Zarate, Aydé Mendoza-Oliva, Omar M Kashmer, Josue E Collazo-Lopez, Charles L White, Marc I Diamon. RNA induces unique tau strains and stabilizes Alzheimer's disease seeds. The Journal of biological chemistry. 2022-06-14. PMID:35700826. |
rna induces unique tau strains and stabilizes alzheimer's disease seeds. |
2022-06-14 |
2023-08-14 |
human |
| Rohit Malik, Sunishtha Kalra, Saurabh Bhatia, Ahmed Al Harrasi, Govind Singh, Syam Mohan, Hafiz A Makeen, Mohammed Albratty, Abdulkarim Meraya, Bojlul Bahar, Murtaza M Tambuwal. Overview of therapeutic targets in management of dementia. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2022-06-14. PMID:35701303. |
it also discusses the incidence and severity of dementia, focusing on alzheimer's disease with its different hypotheses such as aβ cascade hypothesis, tau hypothesis, inflammatory hypothesis, cholinergic and oxidative stress hypothesis. |
2022-06-14 |
2023-08-14 |
Not clear |
| Chunyu Zhou, Cha-Gyun Jung, Mi-Jeong Kim, Atsushi Watanabe, Mona Abdelhamid, Ferdous Taslima, Makoto Michikaw. Insulin Deficiency Increases Sirt2 Level in Streptozotocin-Treated Alzheimer's Disease-Like Mouse Model: Increased Sirt2 Induces Tau Phosphorylation Through ERK Activation. Molecular neurobiology. 2022-06-14. PMID:35701718. |
insulin deficiency increases sirt2 level in streptozotocin-treated alzheimer's disease-like mouse model: increased sirt2 induces tau phosphorylation through erk activation. |
2022-06-14 |
2023-08-14 |
mouse |
| Edmond Teng, Paul T Manser, Karen Pickthorn, Flavia Brunstein, Mira Blendstrup, Sandra Sanabria Bohorquez, Kristin R Wildsmith, Bali Toth, Michael Dolton, Vidya Ramakrishnan, Ashwini Bobbala, Sietske A M Sikkes, Michael Ward, Reina N Fuji, Geoffrey A Kerchne. Safety and Efficacy of Semorinemab in Individuals With Prodromal to Mild Alzheimer Disease: A Randomized Clinical Trial. JAMA neurology. 2022-06-13. PMID:35696185. |
neurofibrillary tangles composed of aggregated tau protein are one of the neuropathological hallmarks of alzheimer disease (ad) and correlate with clinical disease severity. |
2022-06-13 |
2023-08-14 |
Not clear |
| Mary Gannon, Bing Wang, Sara Anne Stringfellow, Stephan Quintin, Itzel Mendoza, Thanushri Srikantha, A Claire Roberts, Takashi Saito, Takaomi C Saido, Erik Roberson, Talene A Yacoubia. 14-3-3θ does not protect against behavioral or pathological deficits in Alzheimer's disease mouse models. eNeuro. 2022-06-13. PMID:35697511. |
alzheimer's disease (ad) is characterized by progressive cognitive impairment associated with synaptic dysfunction and dendritic spine loss and the pathological hallmarks of amyloid beta (aβ) plaques and hyperphosphorylated tau tangles. |
2022-06-13 |
2023-08-14 |
mouse |
| Neha Atulkumar Singh, Nirubol Tosakulwong, Jonathan Graff-Radford, Mary M Machulda, Nha Trang Thu Pham, Irene Sintini, Stephen D Weigand, Christopher G Schwarz, Matthew L Senjem, Minerva M Carrasquillo, Nilufer Ertekin-Taner, Clifford R Jack, Val J Lowe, Keith A Josephs, Jennifer L Whitwel. APOE ε4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-06-12. PMID:35691047. |
apoe ε4 influences medial temporal atrophy and tau deposition in atypical alzheimer's disease. |
2022-06-12 |
2023-08-14 |
Not clear |
| Neha Atulkumar Singh, Nirubol Tosakulwong, Jonathan Graff-Radford, Mary M Machulda, Nha Trang Thu Pham, Irene Sintini, Stephen D Weigand, Christopher G Schwarz, Matthew L Senjem, Minerva M Carrasquillo, Nilufer Ertekin-Taner, Clifford R Jack, Val J Lowe, Keith A Josephs, Jennifer L Whitwel. APOE ε4 influences medial temporal atrophy and tau deposition in atypical Alzheimer's disease. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2022-06-12. PMID:35691047. |
apolipoprotein e (apoe) ε4 is an important genetic risk factor for typical alzheimer's disease (ad), influencing brain volume and tau burden. |
2022-06-12 |
2023-08-14 |
Not clear |
| Xiaohui Ma, Linlin Liu, Jing Men. Retraction notice to "MicroRNA-125b promotes neurons cell apoptosis and tau phosphorylation in Alzheimer's disease" [Neurosci. Lett. 661 (2017) 57-62]. Neuroscience letters. vol 783. 2022-06-12. PMID:35691149. |
retraction notice to "microrna-125b promotes neurons cell apoptosis and tau phosphorylation in alzheimer's disease" [neurosci. |
2022-06-12 |
2023-08-14 |
Not clear |