| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| N Nakahara, Y Iga, F Mizobe, G Kawanish. Effects of intracerebroventricular injection of AF64A on learning behaviors in rats. Japanese journal of pharmacology. vol 48. issue 1. 1989-01-18. PMID:3199599. |
these findings suggested that icv injection of af64a may be useful for producing an experimental amnesia model with hippocampal cholinergic hypofunction like senile dementia of the alzheimer type (sdat), if appropriate learning tests are selected. |
1989-01-18 |
2023-08-11 |
rat |
| A Delacourte, A Defossez, I Ceballos, A Nicole, P M Sine. Preferential localization of copper zinc superoxide dismutase in the vulnerable cortical neurons in Alzheimer's disease. Neuroscience letters. vol 92. issue 3. 1989-01-17. PMID:3200483. |
in the hippocampus of an alzheimer's patient, successive immunostaining of the same tissue section by anti cuzn sod and anti paired helical filaments antisera show that both normal and degenerating cells are labelled by the anti cuzn sod antiserum. |
1989-01-17 |
2023-08-11 |
Not clear |
| M F Beal, R A Clevens, G K Chattha, U M MacGarvey, M F Mazurek, S M Gabrie. Galanin-like immunoreactivity is unchanged in Alzheimer's disease and Parkinson's disease dementia cerebral cortex. Journal of neurochemistry. vol 51. issue 6. 1988-12-20. PMID:2460590. |
in the present study, galanin-like immunoreactivity was measured in the postmortem cerebral cortex and hippocampus of 10 controls and 14 patients who had had alzheimer's disease. |
1988-12-20 |
2023-08-11 |
human |
| A Represa, C Duyckaerts, E Tremblay, J J Hauw, Y Ben-Ar. [Is Alzheimer's senile dementia associated with the phenomena of reactive synaptogenesis in the hippocampus?]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 306. issue 19. 1988-12-15. PMID:2902911. |
[is alzheimer's senile dementia associated with the phenomena of reactive synaptogenesis in the hippocampus?]. |
1988-12-15 |
2023-08-11 |
Not clear |
| A Represa, C Duyckaerts, E Tremblay, J J Hauw, Y Ben-Ar. [Is Alzheimer's senile dementia associated with the phenomena of reactive synaptogenesis in the hippocampus?]. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie. vol 306. issue 19. 1988-12-15. PMID:2902911. |
these results indicate a lack of hippocampal plasticity in senile dementia of alzheimer type. |
1988-12-15 |
2023-08-11 |
Not clear |
| S Itagaki, P L McGeer, H Akiyam. Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue. Neuroscience letters. vol 91. issue 3. 1988-11-30. PMID:2972943. |
cells expressing leucocyte common antigen (lca) as well as t-cytotoxic-suppressor (t8) and t-helper-inducer (t4) antigens were detected in significant numbers in the hippocampus and temporal cortex of alzheimer but not normal brain tissue. |
1988-11-30 |
2023-08-11 |
Not clear |
| D G Amaral, R Insausti, M J Campbel. Distribution of somatostatin immunoreactivity in the human dentate gyrus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 8. issue 9. 1988-11-18. PMID:2459324. |
in particular, alterations of the hippocampal somatostatin system have been associated with both alzheimer's disease and temporal lobe epilepsy. |
1988-11-18 |
2023-08-11 |
human |
| E Birecree, W O Whetsell, C Stoscheck, L E King, L B Nanne. Immunoreactive epidermal growth factor receptors in neuritic plaques from patients with Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 47. issue 5. 1988-11-01. PMID:3049945. |
alzheimer's disease (ad) is characterized neuropathologically by the presence of neuritic plaques (np) in cerebral cortex and hippocampus, as well as intraneuronal neurofibrillary tangles and granulovacuolar degeneration. |
1988-11-01 |
2023-08-11 |
Not clear |
| R Cowburn, J Hardy, P Roberts, R Brigg. Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease. Brain research. vol 452. issue 1-2. 1988-09-15. PMID:2900052. |
in contrast, significant reductions in the number of glutamate terminals were seen in the hippocampus of the alzheimer's samples. |
1988-09-15 |
2023-08-11 |
Not clear |
| A Probst, R Cortés, J Ulrich, J M Palacio. Differential modification of muscarinic cholinergic receptors in the hippocampus of patients with Alzheimer's disease: an autoradiographic study. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401711. |
differential modification of muscarinic cholinergic receptors in the hippocampus of patients with alzheimer's disease: an autoradiographic study. |
1988-09-15 |
2023-08-11 |
Not clear |
| A Probst, R Cortés, J Ulrich, J M Palacio. Differential modification of muscarinic cholinergic receptors in the hippocampus of patients with Alzheimer's disease: an autoradiographic study. Brain research. vol 450. issue 1-2. 1988-09-15. PMID:3401711. |
we have used quantitative light microscopic autoradiographic techniques to analyze changes in muscarinic cholinergic receptors in the hippocampus in alzheimer type dementia (atd). |
1988-09-15 |
2023-08-11 |
Not clear |
| M J de Leon, T McRae, J R Tsai, A E George, D L Marcus, M Freedman, A P Wolf, B McEwe. Abnormal cortisol response in Alzheimer's disease linked to hippocampal atrophy. Lancet (London, England). vol 2. issue 8607. 1988-09-08. PMID:2899791. |
abnormal cortisol response in alzheimer's disease linked to hippocampal atrophy. |
1988-09-08 |
2023-08-11 |
Not clear |
| R E Powers, R G Struble, M F Casanova, D T O'Connor, C A Kitt, D L Pric. Innervation of human hippocampus by noradrenergic systems: normal anatomy and structural abnormalities in aging and in Alzheimer's disease. Neuroscience. vol 25. issue 2. 1988-09-01. PMID:3399052. |
innervation of human hippocampus by noradrenergic systems: normal anatomy and structural abnormalities in aging and in alzheimer's disease. |
1988-09-01 |
2023-08-11 |
human |
| B J Crain, P C Burge. The laminar distribution of neuritic plaques in the fascia dentata of patients with Alzheimer's disease. Acta neuropathologica. vol 76. issue 1. 1988-08-25. PMID:3394497. |
examination of 19 brains from patients with alzheimer's disease showed approximately the same number of plaques in the stratum moleculare of the fascia dentata and in ca1 (sommer's sector) of the hippocampus, even though the area of the latter is much greater. |
1988-08-25 |
2023-08-11 |
Not clear |
| J Chapman, O Bachar, A D Korczyn, E Wertman, D M Michaelso. Antibodies to cholinergic neurons in Alzheimer's disease. Journal of neurochemistry. vol 51. issue 2. 1988-08-24. PMID:3292704. |
alzheimer's disease (ad) is associated with degenerative changes in nuclei of the basal forebrain which provide most of the cholinergic input to the cortex and hippocampus and with a reduction in presynaptic cholinergic parameters in these areas. |
1988-08-24 |
2023-08-11 |
human |
| C M Thompson, W R Markesbery, W D Ehmann, Y X Mao, D E Vanc. Regional brain trace-element studies in Alzheimer's disease. Neurotoxicology. vol 9. issue 1. 1988-08-23. PMID:3393299. |
alzheimer's disease (ad) brain trace-element imbalances in the amygdala, hippocampus and nucleus basalis of meynert (nbm) are found in most cases to be consistent with those previously reported in samples derived principally from ad cerebral cortex (ehmann et al., 1986). |
1988-08-23 |
2023-08-11 |
Not clear |
| J J Hagan, J H Jansen, C L Broekkam. Selective behavioural impairment after acute intoxication with trimethyltin (TMT) in rats. Neurotoxicology. vol 9. issue 1. 1988-08-23. PMID:3393303. |
tmt lesioned rats may provide a suitable functional model for the partial hippocampal and temporal lobe pathology characteristic of alzheimer's disease. |
1988-08-23 |
2023-08-11 |
rat |
| M P Mattso. Neurotransmitters in the regulation of neuronal cytoarchitecture. Brain research. vol 472. issue 2. 1988-08-08. PMID:2898278. |
the neurotransmitter glutamate was found to specifically affect the cytoarchitecture of hippocampal pyramidal neuron dendrites in a graded manner which suggests that glutamate may be involved in: establishing hippocampal circuitry during brain development; maintaining and modifying circuitry in the adult; and inducing neurodegeneration in several disorders including epilepsy, alzheimer's disease, and stroke. |
1988-08-08 |
2023-08-11 |
Not clear |
| M L Schmidt, R E Gur, R C Gur, J Q Trojanowsk. Intraneuronal and extracellular neurofibrillary tangles exhibit mutually exclusive cytoskeletal antigens. Annals of neurology. vol 23. issue 2. 1988-07-14. PMID:3377439. |
we examined the possibility that neurofibrillary tangles (nfts) were heterogeneous in postmortem hippocampus from 22 patients with or without senile dementia of the alzheimer type. |
1988-07-14 |
2023-08-11 |
Not clear |
| A A Farooqui, L Liss, L A Horrock. Stimulation of lipolytic enzymes in Alzheimer's disease. Annals of neurology. vol 23. issue 3. 1988-07-05. PMID:3377450. |
these results indicate a stimulation of lipolytic enzymes in nucleus basalis and hippocampus regions in patients with alzheimer's disease. |
1988-07-05 |
2023-08-11 |
human |