| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C P Mauriz. Dementia--the failure of hippocampal plasticity and dreams. Is there a preventative role for melatonin? Medical hypotheses. vol 24. issue 1. 1987-12-08. PMID:3312972. |
anatomic, chemical, physiologic, pathologic and clinical evidence suggests that senile dementia (alzheimer's disease) is a dysfunction of the hippocampus. |
1987-12-08 |
2023-08-11 |
Not clear |
| I N Bogolepov. [The hippocampus in patients with different forms of senile dementia]. Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952). vol 87. issue 7. 1987-12-08. PMID:3673394. |
using cytoarchitectonic and quantitative techniques the hippocampus and dentate fascia of the adult human brain were studied in normal subjects and in patients with senile dementia and alzheimer's disease. |
1987-12-08 |
2023-08-11 |
human |
| J C Winter, D T Pett. The effects of 8-hydroxy-2-(di-n-propylamino)tetralin and other serotonergic agonists on performance in a radial maze: a possible role for 5-HT1A receptors in memory. Pharmacology, biochemistry, and behavior. vol 27. issue 4. 1987-10-29. PMID:2958885. |
the present results taken in light of 8-oh-dpat's preferential binding to 5-ht1a receptors, the high density of these receptors in hippocampus, and the observation that the number of 5-ht1a receptors is decreased in alzheimer's disease, suggest a possible role for this serotonergic receptor subtype in memory. |
1987-10-29 |
2023-08-11 |
rat |
| S Kuroda, S Otsuki, Y Hayash. Diffuse Lewy body disease: an autopsy case. Acta medica Okayama. vol 41. issue 3. 1987-10-16. PMID:2820201. |
autopsy revealed numerous senile plaques in the cerebral cortex and alzheimer's neurofibrillary tangles in the inferior temporal lobe and hippocampus. |
1987-10-16 |
2023-08-11 |
Not clear |
| B T Hyman, G W Van Hoesen, A R Damasi. Alzheimer's disease: glutamate depletion in the hippocampal perforant pathway zone. Annals of neurology. vol 22. issue 1. 1987-09-30. PMID:2443073. |
alzheimer's disease: glutamate depletion in the hippocampal perforant pathway zone. |
1987-09-30 |
2023-08-11 |
human |
| A Delacourte, A Defossez, P Persuy, M C Peer. Observation of morphological relationships between angiopathic blood vessels and degenerative neurites in Alzheimer's disease. Virchows Archiv. A, Pathological anatomy and histopathology. vol 411. issue 3. 1987-09-10. PMID:2441514. |
using simultaneous histochemical and immunohistochemical labellings on the same tissue sections of alzheimer cortex (association cortex and hippocampus), the different lesions were stained with great sensitivity and specificity. |
1987-09-10 |
2023-08-11 |
Not clear |
| E K Perry, R H Perry, C J Smith, D J Dick, J M Candy, J A Edwardson, A Fairbairn, G Blesse. Nicotinic receptor abnormalities in Alzheimer's and Parkinson's diseases. Journal of neurology, neurosurgery, and psychiatry. vol 50. issue 6. 1987-09-02. PMID:2956364. |
whilst muscarinic receptor binding is generally reported to be normal or near normal, findings are reported which indicate substantial reductions of hippocampal nicotinic (high affinity nicotine) binding (occurring in conjunction with decreased choline acetyltransferase) in both alzheimer's and parkinson's but not huntington's disease. |
1987-09-02 |
2023-08-11 |
human |
| J Ulrich, M Haugh, B H Anderton, A Probst, C Lautenschlager, B Hi. Alzheimer dementia and Pick's disease: neurofibrillary tangles and Pick bodies are associated with identical phosphorylated neurofilament epitopes. Acta neuropathologica. vol 73. issue 3. 1987-08-28. PMID:2441559. |
sections of formaldehyde-fixed paraffin-embedded cortical and hippocampal brain tissue from five cases with senile dementia of alzheimer type (sdat) and five cases with pick's disease (pd) were immunostained with the monoclonal antibodies (mabs) 147, rt 97, bf 10 and 8d8 with and without pretreatment with alkaline phosphatase (ap) or trypsin (tr). |
1987-08-28 |
2023-08-11 |
Not clear |
| J Kahn, B H Anderton, C C Miller, J N Wood, M M Esir. Staining with monoclonal antibodies to neurofilaments distinguishes between subpopulations of neurofibrillary tangles, between groups of axons and between groups of dendrites. Journal of neurology. vol 234. issue 4. 1987-08-28. PMID:3112314. |
in alzheimer's disease, mab 1215 recognizes only a subpopulation of neurofibrillary tangles and stains a proportion of tangles in the hippocampus but none of those in the olfactory bulb. |
1987-08-28 |
2023-08-11 |
Not clear |
| K J Reinikainen, P J Riekkinen, T Halonen, M Laaks. Decreased muscarinic receptor binding in cerebral cortex and hippocampus in Alzheimer's disease. Life sciences. vol 41. issue 4. 1987-08-20. PMID:3600187. |
decreased muscarinic receptor binding in cerebral cortex and hippocampus in alzheimer's disease. |
1987-08-20 |
2023-08-11 |
Not clear |
| K J Reinikainen, P J Riekkinen, T Halonen, M Laaks. Decreased muscarinic receptor binding in cerebral cortex and hippocampus in Alzheimer's disease. Life sciences. vol 41. issue 4. 1987-08-20. PMID:3600187. |
muscarinic (cholinergic) receptor binding sites (mrb) were studied by determining the 3h-qnb binding in four cortical areas and hippocampus of 20 histologically confirmed alzheimer patients and comparing these with corresponding controls. |
1987-08-20 |
2023-08-11 |
Not clear |
| K J Reinikainen, P J Riekkinen, T Halonen, M Laaks. Decreased muscarinic receptor binding in cerebral cortex and hippocampus in Alzheimer's disease. Life sciences. vol 41. issue 4. 1987-08-20. PMID:3600187. |
alzheimer patients dying at younger age (less than or equal to 80) with profound decrease in choline-acetyltransferase activity (by 61-85%) and without any, possibly mrb modifying, drug treatment showed 30% decrease in mrb in the frontal cortex (p less than 0.05), 28% in the temporal cortex (p less than 0.05) and 37% in the hippocampus (p less than 0.01). |
1987-08-20 |
2023-08-11 |
Not clear |
| F Fazekas, J B Chawluk, A Alavi, H I Hurtig, R A Zimmerma. MR signal abnormalities at 1.5 T in Alzheimer's dementia and normal aging. AJR. American journal of roentgenology. vol 149. issue 2. 1987-08-17. PMID:3496763. |
areas of high signal intensity affecting hippocampal and sylvian cortex were also present in five alzheimer and two multiinfarct dementia patients, but absent in controls. |
1987-08-17 |
2023-08-11 |
human |
| H A Hartman. Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 46. issue 4. 1987-08-07. PMID:2439658. |
neuronal rna in relation to neuronal loss and neurofibrillary pathology in the hippocampus in alzheimer's disease. |
1987-08-07 |
2023-08-11 |
Not clear |
| B T Hyman, L J Kromer, G W Van Hoese. Reinnervation of the hippocampal perforant pathway zone in Alzheimer's disease. Annals of neurology. vol 21. issue 3. 1987-08-07. PMID:3606033. |
reinnervation of the hippocampal perforant pathway zone in alzheimer's disease. |
1987-08-07 |
2023-08-11 |
Not clear |
| Y Nakagawa, S Nakamura, Y Kaśe, T Noguchi, T Ishihar. Colchicine lesions in the rat hippocampus mimic the alterations of several markers in Alzheimer's disease. Brain research. vol 408. issue 1-2. 1987-07-30. PMID:2885069. |
colchicine lesions in the rat hippocampus mimic the alterations of several markers in alzheimer's disease. |
1987-07-30 |
2023-08-11 |
rat |
| Y Nakagawa, S Nakamura, Y Kaśe, T Noguchi, T Ishihar. Colchicine lesions in the rat hippocampus mimic the alterations of several markers in Alzheimer's disease. Brain research. vol 408. issue 1-2. 1987-07-30. PMID:2885069. |
some of the changes caused by hippocampal infusion of colchicine resemble those seen in alzheimer's disease suggesting the use of such rats as one model for the disease. |
1987-07-30 |
2023-08-11 |
rat |
| S Bahmanyar, G A Higgins, D Goldgaber, D A Lewis, J H Morrison, M C Wilson, S K Shankar, D C Gajduse. Localization of amyloid beta protein messenger RNA in brains from patients with Alzheimer's disease. Science (New York, N.Y.). vol 237. issue 4810. 1987-07-29. PMID:3299701. |
this messenger rna was also present in the neurons of all the hippocampal fields from monkeys, normal humans and, although to a lesser extent in cornu ammonis 1, patients with alzheimer's disease. |
1987-07-29 |
2023-08-11 |
monkey |
| P H Gibso. Ultrastructural abnormalities in the cerebral neocortex and hippocampus associated with Alzheimer's disease and aging. Acta neuropathologica. vol 73. issue 1. 1987-07-24. PMID:3604576. |
ultrastructural abnormalities in the cerebral neocortex and hippocampus associated with alzheimer's disease and aging. |
1987-07-24 |
2023-08-11 |
Not clear |
| P H Gibso. Ultrastructural abnormalities in the cerebral neocortex and hippocampus associated with Alzheimer's disease and aging. Acta neuropathologica. vol 73. issue 1. 1987-07-24. PMID:3604576. |
lesions of the frontal and temporal neocortices and hippocampus typically found in alzheimer's disease were looked for with the electron microscope in 119 autopsy cases whose ages ranged from 24-93 years. |
1987-07-24 |
2023-08-11 |
Not clear |