| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Nordberg, P Nyberg, R Adolfsson, B Winbla. Cholinergic topography in Alzheimer brains: a comparison with changes in the monoaminergic profile. Journal of neural transmission. vol 69. issue 1-2. 1987-07-16. PMID:3585318. |
the topographical distribution of the choline acetyltransferase (chat) activity and the number of muscarinic binding sites was studied in the anterio-posterior direction of the caudate nucleus, hippocampus, globus pallidus and putamen of four subjects with senile dementia of alzheimer type (ad/sdat) and in the same regions in six controls. |
1987-07-16 |
2023-08-11 |
human |
| M F Mazurek, M F Beal, E D Bird, J B Marti. Oxytocin in Alzheimer's disease: postmortem brain levels. Neurology. vol 37. issue 6. 1987-07-01. PMID:3587615. |
oxy concentration was increased 33% in the hippocampus and temporal cortex of alzheimer brains (p less than 0.05), but normal in all other regions examined. |
1987-07-01 |
2023-08-11 |
Not clear |
| M F Mazurek, M F Beal, E D Bird, J B Marti. Oxytocin in Alzheimer's disease: postmortem brain levels. Neurology. vol 37. issue 6. 1987-07-01. PMID:3587615. |
elevated hippocampal oxy levels may contribute to the memory disturbance associated with alzheimer's disease. |
1987-07-01 |
2023-08-11 |
Not clear |
| J M Hiller, Y Itzhak, E J Simo. Selective changes in mu, delta and kappa opioid receptor binding in certain limbic regions of the brain in Alzheimer's disease patients. Brain research. vol 406. issue 1-2. 1987-06-05. PMID:3032356. |
total binding and binding to mu and delta receptors in frontal cortex, caudate and hippocampus of alzheimer's disease brains was indistinguishable from levels seen in these brain areas from control individuals. |
1987-06-05 |
2023-08-11 |
Not clear |
| R D Terry, L A Hansen, R DeTeresa, P Davies, H Tobias, R Katzma. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. Journal of neuropathology and experimental neurology. vol 46. issue 3. 1987-05-19. PMID:2881985. |
senile dementia of the alzheimer type (sdat) is typified pathologically by neuritic plaques (np) and neurofibrillary tangles (nft) in the neocortex and hippocampus. |
1987-05-19 |
2023-08-11 |
Not clear |
| H Yamaguchi, M Morimatsu, S Hirai, K Takahash. Alzheimer's neurofibrillary tangles are penetrated by astroglial processes and appear eosinophilic in their final stages. Acta neuropathologica. vol 72. issue 3. 1987-05-18. PMID:2436433. |
alzheimer's neurofibrillary tangles (ant) in the hippocampal area were studied immunohistochemically using antisera against glial fibrillary acidic protein (gfap) and s-100 protein in 48 patients with or without dementia between 52 and 92 years old. |
1987-05-18 |
2023-08-11 |
Not clear |
| W F Maragos, D C Chu, A B Young, C J D'Amato, J B Penne. Loss of hippocampal [3H]TCP binding in Alzheimer's disease. Neuroscience letters. vol 74. issue 3. 1987-05-08. PMID:3031556. |
loss of hippocampal [3h]tcp binding in alzheimer's disease. |
1987-05-08 |
2023-08-11 |
Not clear |
| W F Maragos, D C Chu, A B Young, C J D'Amato, J B Penne. Loss of hippocampal [3H]TCP binding in Alzheimer's disease. Neuroscience letters. vol 74. issue 3. 1987-05-08. PMID:3031556. |
we have previously demonstrated a marked loss in n-methyl-d-aspartate (nmda) receptors in the hippocampus and cerebral cortex of patients dying with dementia of the alzheimer type (dat). |
1987-05-08 |
2023-08-11 |
Not clear |
| D T Monaghan, J W Geddes, D Yao, C Chung, C W Cotma. [3H]TCP binding sites in Alzheimer's disease. Neuroscience letters. vol 73. issue 2. 1987-04-15. PMID:3029638. |
quantitative autoradiography was used to determine the density and distribution of [3h]1-[1-(2-thienyl)-cyclohexyl]piperidine ([3h]tcp) binding sites in human hippocampal tissue sections from control and alzheimer's disease patients. |
1987-04-15 |
2023-08-11 |
human |
| D T Monaghan, J W Geddes, D Yao, C Chung, C W Cotma. [3H]TCP binding sites in Alzheimer's disease. Neuroscience letters. vol 73. issue 2. 1987-04-15. PMID:3029638. |
[3h]tcp binding in the ca1 region from alzheimer's patients was reduced an average of 40% while the other hippocampal regions were unaffected. |
1987-04-15 |
2023-08-11 |
human |
| J Hardy, R Cowburn, A Barton, G Reynolds, P Dodd, P Wester, A M O'Carroll, E Lofdahl, B Winbla. A disorder of cortical GABAergic innervation in Alzheimer's disease. Neuroscience letters. vol 73. issue 2. 1987-04-15. PMID:3822251. |
70%) loss of cortical and hippocampal gaba terminals in alzheimer brain. |
1987-04-15 |
2023-08-11 |
Not clear |
| B Szelies, A Karenber. [Disorders of glucose metabolism in Pick's disease]. Fortschritte der Neurologie-Psychiatrie. vol 54. issue 12. 1987-03-30. PMID:3493192. |
pick's disease can be differentiated against presenile dementia represented by alzheimer's disease in that the pattern of reduced metabolism characteristic of alzheimer's disease is different from that of pick's disease where in accordance with the clinical syndrome the glucose metabolism in the frontal and temporobasal regions in reduced, involving also the structures of the hippocampus and an equally significant reduction of glucose metabolism in the caudate nucleus. |
1987-03-30 |
2023-08-11 |
Not clear |
| J W Geddes, H Chang-Chui, S M Cooper, I T Lott, C W Cotma. Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease. Brain research. vol 399. issue 1. 1987-03-19. PMID:2879613. |
density and distribution of nmda receptors in the human hippocampus in alzheimer's disease. |
1987-03-19 |
2023-08-11 |
human |
| J W Geddes, H Chang-Chui, S M Cooper, I T Lott, C W Cotma. Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease. Brain research. vol 399. issue 1. 1987-03-19. PMID:2879613. |
we examined the distribution and density of n-methyl-d-aspartate (nmda) displaceable l-[3h]glutamate binding sites in human hippocampal samples obtained postmortem from alzheimer's disease (ad) patients and from age-matched controls. |
1987-03-19 |
2023-08-11 |
human |
| J T Greenamyre, J B Penney, C J D'Amato, A B Youn. Dementia of the Alzheimer's type: changes in hippocampal L-[3H]glutamate binding. Journal of neurochemistry. vol 48. issue 2. 1987-02-19. PMID:2878980. |
dementia of the alzheimer's type: changes in hippocampal l-[3h]glutamate binding. |
1987-02-19 |
2023-08-11 |
Not clear |
| J A Doebler, W R Markesbery, A Anthony, R E Rhoad. Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 46. issue 1. 1987-02-13. PMID:2432192. |
neuronal rna in relation to neuronal loss and neurofibrillary pathology in the hippocampus in alzheimer's disease. |
1987-02-13 |
2023-08-11 |
Not clear |
| J A Doebler, W R Markesbery, A Anthony, R E Rhoad. Neuronal RNA in relation to neuronal loss and neurofibrillary pathology in the hippocampus in Alzheimer's disease. Journal of neuropathology and experimental neurology. vol 46. issue 1. 1987-02-13. PMID:2432192. |
topographic analyses were performed on the distribution of neuronal rna loss in relation to local neuronal loss and neurofibrillary degeneration in the hippocampal region of brains of patients with alzheimer's disease (ad). |
1987-02-13 |
2023-08-11 |
Not clear |
| P L McGeer, E G McGeer, H Kamo, K Won. Positron emission tomography and the possible origins of cytopathology in Alzheimer's disease. Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:3541048. |
the cholinergic cells of the medial basal forebrain show a pathological dropout in alzheimer's disease which accounts for the decline in choline acetyltransferase in the cerebral cortex and hippocampus. |
1987-02-06 |
2023-08-11 |
Not clear |
| E K Perry, R H Perry, C J Smith, D Purohit, J Bonham, D J Dick, J M Candy, J A Edwardson, A Fairbair. Cholinergic receptors in cognitive disorders. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques. vol 13. issue 4 Suppl. 1987-02-06. PMID:3791066. |
cholinergic receptors (muscarinic subtypes m1 and m2, and putative nicotinic binding) have been examined in the hippocampus obtained at autopsy from a variety of patients with cognitive disorders (alzheimer's, parkinson's, and huntington's diseases, down's syndrome and alcoholic dementia) and compared with neurologically normal controls and cases of motor neuron disease. |
1987-02-06 |
2023-08-11 |
Not clear |
| C G Gottfries, T Bartfai, A Carlsson, S Eckernäs, L Svennerhol. Multiple biochemical deficits in both gray and white matter of Alzheimer brains. Progress in neuro-psychopharmacology & biological psychiatry. vol 10. issue 3-5. 1987-02-06. PMID:3797685. |
in the brains from the alzheimer patients the examination of gray matter (caudate nucleus and hippocampus) showed a significant reduced activity of choline-acetyl transferase (cat) and a reduction of acetylcholinesterase (ache) that bordered significance in the hippocampus. |
1987-02-06 |
2023-08-11 |
cat |