| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexandra Horvath, Patrick Quinlan, Carl Eckerström, N David Åberg, Anders Wallin, Johan Svensso. Low Serum Insulin-like Growth Factor-I Is Associated with Decline in Hippocampal Volume in Stable Mild Cognitive Impairment but not in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-06-20. PMID:35723105. |
low serum insulin-like growth factor-i is associated with decline in hippocampal volume in stable mild cognitive impairment but not in alzheimer's disease. |
2022-06-20 |
2023-08-14 |
human |
| Alexandra Horvath, Patrick Quinlan, Carl Eckerström, N David Åberg, Anders Wallin, Johan Svensso. Low Serum Insulin-like Growth Factor-I Is Associated with Decline in Hippocampal Volume in Stable Mild Cognitive Impairment but not in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-06-20. PMID:35723105. |
serum insulin-like growth factor-i (igf-i) has shown some association with hippocampal volume in healthy subjects, but this relation has not been investigated in stable mild cognitive impairment (smci) or alzheimer's disease (ad). |
2022-06-20 |
2023-08-14 |
human |
| Uttam Khatri, Goo-Rak Kwo. Alzheimer's Disease Diagnosis and Biomarker Analysis Using Resting-State Functional MRI Functional Brain Network With Multi-Measures Features and Hippocampal Subfield and Amygdala Volume of Structural MRI. Frontiers in aging neuroscience. vol 14. 2022-06-16. PMID:35707703. |
alzheimer's disease diagnosis and biomarker analysis using resting-state functional mri functional brain network with multi-measures features and hippocampal subfield and amygdala volume of structural mri. |
2022-06-16 |
2023-08-14 |
Not clear |
| Lindsey A Smith, Anthoni M Goodman, Lori L McMaho. Dentate Granule Cells Are Hyperexcitable in the TgF344-AD Rat Model of Alzheimer's Disease. Frontiers in synaptic neuroscience. vol 14. 2022-06-10. PMID:35685246. |
the dentate gyrus is both a critical gatekeeper for hippocampal signal processing and one of the first brain regions to become dysfunctional in alzheimer's disease (ad). |
2022-06-10 |
2023-08-14 |
rat |
| Mohsen Sheykhhasan, Razieh Amini, Sara Soleimani Asl, Massoud Saidijam, Seyed Mahmoud Hashemi, Rezvan Najaf. Neuroprotective effects of coenzyme Q10-loaded exosomes obtained from adipose-derived stem cells in a rat model of Alzheimer's disease. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 152. 2022-06-09. PMID:35679720. |
according to the findings of this study, exo+ coq10 enhanced cognition and memory deficiency in alzheimer's disease by boosting bdnf and sox2 levels in the hippocampus. |
2022-06-09 |
2023-08-14 |
rat |
| Tim E Moors, Daniel Mona, Stefan Luehe, Gonzalo Duran-Pacheco, Liz Spycher, Olaf Mundigl, Klaus Kaluza, Sylwia Huber, Melanie N Hug, Thomas Kremer, Mirko Ritter, Sebastian Dziadek, Gregor Dernick, Wilma D J van de Berg, Markus Britschg. Multi-platform quantitation of alpha-synuclein human brain proteoforms suggests disease-specific biochemical profiles of synucleinopathies. Acta neuropathologica communications. vol 10. issue 1. 2022-06-06. PMID:35659116. |
to address this, we generated sequential biochemical extracts of the substantia nigra, putamen and hippocampus from 28 donors diagnosed and neuropathologically-confirmed with different synucleinopathies (pd/pdd/dlb/msa), as well as alzheimer's disease, progressive supranuclear palsy, and aged normal subjects. |
2022-06-06 |
2023-08-14 |
human |
| Reza Aameri, Hossein Ghorbani, Hamid Reza Bazrafshan, Fatemeh Zahra Gharib, Bahareh Koran. Iranian Thyme honey plays behavioral, cellular and molecular important roles as an amazing preventive and therapeutic agent in the brain of Alzheimer's rat model. Neuroscience letters. 2022-06-06. PMID:35660648. |
alzheimer's disease (ad) is a progressive neurodegenerative disorder with neuronal loss in the hippocampus. |
2022-06-06 |
2023-08-14 |
rat |
| Maya A Hanspal, Sébastien Gilloti. A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662190. |
a new age in understanding adult hippocampal neurogenesis in alzheimer's disease. |
2022-06-06 |
2023-08-14 |
human |
| Maya A Hanspal, Sébastien Gilloti. A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662190. |
the rate of adult hippocampal neurogenesis decreases with aging and a premature impairment of adult hippocampal neurogenesis has been observed both in animal models of alzheimer's disease and human post-mortem tissues. |
2022-06-06 |
2023-08-14 |
human |
| Maya A Hanspal, Sébastien Gilloti. A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662190. |
the causal relationship between adult hippocampal neurogenesis and the development of alzheimer's disease pathology has, however, not been established. |
2022-06-06 |
2023-08-14 |
human |
| Maya A Hanspal, Sébastien Gilloti. A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662190. |
while it is tempting to postulate that adult hippocampal neurogenesis could be leveraged to improve cognitive deficits in alzheimer's disease, consensual results have yet to be reached to fully explore this hypothesis. |
2022-06-06 |
2023-08-14 |
human |
| Maya A Hanspal, Sébastien Gilloti. A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease. Neural regeneration research. vol 17. issue 12. 2022-06-06. PMID:35662190. |
in this review, we discuss how the recent progress in identifying molecular pathways in adult hippocampal neurogenesis provides a good framework to initiate strategies for drug-based intervention in neurodegenerative diseases, especially in alzheimer's disease. |
2022-06-06 |
2023-08-14 |
human |
| Hanmu Guo, Lexin Zheng, Heng Xu, Qiuyu Pang, Zhiyang Ren, Yuan Gao, Tao Wan. Neurobiological Links between Stress, Brain Injury, and Disease. Oxidative medicine and cellular longevity. vol 2022. 2022-06-06. PMID:35663199. |
this review summarizes various stress models and their applications and then discusses the effects and mechanisms of stress on key brain regions-including the hippocampus, hypothalamus, amygdala, and prefrontal cortex-and in brain injuries and diseases-including alzheimer's disease, stroke, traumatic brain injury, and epilepsy. |
2022-06-06 |
2023-08-14 |
Not clear |
| Akanksha Malaiya, Mansha Singhai, Manisha Singh, Shiv Kumar Prajapati, Hira Choudhury, Mahak Fatima, Amit Alexander, Sunil Kumar Dubey, Khaled Greish, Prashant Kesharwan. Recent Update on the Alzheimer's Disease Progression, Diagnosis and Treatment Approaches. Current drug targets. 2022-06-03. PMID:35657283. |
the resulting plaque found in extracellular space in the ad brain and hippocampus region, known as senile plaques, is the characteristic feature underlying alzheimer's pathology, where the role of amy-loid-β (aβ) peptide formation from proteolytic cleavage of amyloid precursor protein (app) by secre-tase enzyme is eminent. |
2022-06-03 |
2023-08-14 |
Not clear |
| Connie A Mackenzie-Gray Scott, Kenneth A Pelkey, Adam P Caccavano, Daniel Abebe, Mandy Lai, Khayla N Black, Nicolette D Brown, Andrew J Trevelyan, Chris J McBai. Resilient Hippocampal Gamma Rhythmogenesis and Parvalbumin-Expressing Interneuron Function Before and After Plaque Burden in Frontiers in synaptic neuroscience. vol 14. 2022-06-01. PMID:35645763. |
resilient hippocampal gamma rhythmogenesis and parvalbumin-expressing interneuron function before and after plaque burden in recent studies have implicated impaired parvalbumin fast-spiking interneuron (pvin) function as a precipitating factor underlying abnormalities in network synchrony, oscillatory rhythms, and cognition associated with alzheimer's disease (ad). |
2022-06-01 |
2023-08-13 |
Not clear |
| Pengcheng Xia, Jing Chen, Xiaohui Bai, Ming Li, Le Wang, Zhiming L. Key gene network related to primary ciliary dyskinesia in hippocampus of patients with Alzheimer's disease revealed by weighted gene co-expression network analysis. BMC neurology. vol 22. issue 1. 2022-05-31. PMID:35637434. |
key gene network related to primary ciliary dyskinesia in hippocampus of patients with alzheimer's disease revealed by weighted gene co-expression network analysis. |
2022-05-31 |
2023-08-13 |
human |
| Tuğberk Andaç Topkan, Nesrin Erdogan, Berrak Barutcu, Emetullah Cindil, E Turgut Tali, Yahya Karama. Volumetric Assessment of Hippocampus and Subcortical Gray Matter Regions in Alzheimer Disease and Amnestic Mild Cognitive Impairment. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology. vol 35. issue 2. 2022-05-31. PMID:35639010. |
volumetric assessment of hippocampus and subcortical gray matter regions in alzheimer disease and amnestic mild cognitive impairment. |
2022-05-31 |
2023-08-13 |
Not clear |
| Md Ataur Rahman, M D Hasanur Rahman, A N M Mamun-Or-Rashid, Hongik Hwang, Sooyoung Chung, Bonglee Kim, Hyewhon Rhi. Autophagy Modulation in Aggresome Formation: Emerging Implications and Treatments of Alzheimer's Disease. Biomedicines. vol 10. issue 5. 2022-05-28. PMID:35625764. |
alzheimer's disease (ad) is one of the most prevailing neurodegenerative diseases in the world, which is characterized by memory dysfunction and the formation of tau and amyloid β (aβ) aggregates in multiple brain regions, including the hippocampus and cortex. |
2022-05-28 |
2023-08-13 |
Not clear |
| Virginie Dinet, Louiza Arouche-Delaperche, Julie Dégardin, Marie-Christine Naud, Serge Picaud, Slavica Kranti. Concomitant Retinal Alterations in Neuronal Activity and TNFα Pathway Are Detectable during the Pre-Symptomatic Stage in a Mouse Model of Alzheimer's Disease. Cells. vol 11. issue 10. 2022-05-28. PMID:35626688. |
the pre-symptomatic stage of alzheimer's disease (ad) is associated with increased amyloid-β (aβ) precursor protein (app) processing and aβ accumulation in the retina and hippocampus. |
2022-05-28 |
2023-08-13 |
mouse |
| Dariusz Świetlik, Jacek Białowąs, Aida Kusiak, Marta Krasn. Virtual Therapy with the NMDA Antagonist Memantine in Hippocampal Models of Moderate to Severe Alzheimer's Disease, in Silico Trials. Pharmaceuticals (Basel, Switzerland). vol 15. issue 5. 2022-05-28. PMID:35631372. |
virtual therapy with the nmda antagonist memantine in hippocampal models of moderate to severe alzheimer's disease, in silico trials. |
2022-05-28 |
2023-08-13 |
Not clear |