| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Patricia Molina-Martínez, Rubén Corpas, Elisa García-Lara, Marta Cosín-Tomás, Rosa Cristòfol, Perla Kaliman, Carme Solà, José Luis Molinuevo, Raquel Sánchez-Valle, Anna Antonell, Albert Lladó, Coral Sanfeli. Microglial Hyperreactivity Evolved to Immunosuppression in the Hippocampus of a Mouse Model of Accelerated Aging and Alzheimer's Disease Traits. Frontiers in aging neuroscience. vol 12. 2021-02-16. PMID:33584248. |
microglial hyperreactivity evolved to immunosuppression in the hippocampus of a mouse model of accelerated aging and alzheimer's disease traits. |
2021-02-16 |
2023-08-13 |
mouse |
| Dewei Wang, Ping Wang, Xianli Bian, Shunliang Xu, Qingbo Zhou, Yuan Zhang, Mao Ding, Min Han, Ling Huang, Jianzhong Bi, Yuxiu Jia, Zhaohong Xi. Elevated plasma levels of exosomal BACE1‑AS combined with the volume and thickness of the right entorhinal cortex may serve as a biomarker for the detection of Alzheimer's disease. Molecular medicine reports. vol 22. issue 1. 2021-02-16. PMID:32377715. |
long non-coding rna (lncrna) and exosomes are involved in the pathological process of alzheimer's disease (ad), the pathological changes of which are usually first observed in the entorhinal cortex and hippocampus. |
2021-02-16 |
2023-08-13 |
human |
| Chiara Milani, Francesca Farina, Laura Botto, Luca Massimino, Elena Lonati, Elisabetta Donzelli, Elisa Ballarini, Luca Crippa, Paola Marmiroli, Alessandra Bulbarelli, Paola Palestin. Systemic Exposure to Air Pollution Induces Oxidative Stress and Inflammation in Mouse Brain, Contributing to Neurodegeneration Onset. International journal of molecular sciences. vol 21. issue 10. 2021-02-16. PMID:32456361. |
proteins related to oxidative stress and inflammation, as well as alzheimer's disease markers, were examined in the hippocampus, cerebellum, and the rest of the brain (rob). |
2021-02-16 |
2023-08-13 |
mouse |
| Ha-Na Woo, Sujeong Park, Hae Lin Kim, Min-Kyo Jung, Chan-Gi Pack, Jinsu Park, Yoonsuk Cho, Dong-Gyu Jo, Dong Kyu Kim, Inhee Mook-Jung, Seong Who Kim, Heuiran Le. miR-351-5p/Miro2 axis contributes to hippocampal neural progenitor cell death via unbalanced mitochondrial fission. Molecular therapy. Nucleic acids. vol 23. 2021-02-13. PMID:33575111. |
adult hippocampal neurogenesis supports the structural and functional plasticity of the brain, while its decline is associated with neurodegeneration common in alzheimer's disease (ad). |
2021-02-13 |
2023-08-13 |
mouse |
| Hyunju Kim, Bora Kim, Hye-Sun Kim, Joo-Youn Ch. Nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xFAD mice, an Alzheimer's disease animal model. Molecular brain. vol 13. issue 1. 2021-02-12. PMID:32033569. |
nicotinamide attenuates the decrease in dendritic spine density in hippocampal primary neurons from 5xfad mice, an alzheimer's disease animal model. |
2021-02-12 |
2023-08-13 |
mouse |
| Domenica Donatella Li Puma, Roberto Piacentini, Claudio Grass. Does Impairment of Adult Neurogenesis Contribute to Pathophysiology of Alzheimer's Disease? A Still Open Question. Frontiers in molecular neuroscience. vol 13. 2021-02-10. PMID:33551741. |
several studies associated altered hippocampal neurogenesis with aging and alzheimer's disease (ad). |
2021-02-10 |
2023-08-13 |
Not clear |
| Aonan Zhao, Fang Fang, Binyin Li, Yan Chen, Yinghui Qiu, Yanli Wu, Wei Xu, Yulei Den. Visual Abnormalities Associate With Hippocampus in Mild Cognitive Impairment and Early Alzheimer's Disease. Frontiers in aging neuroscience. vol 12. 2021-02-10. PMID:33551787. |
visual abnormalities associate with hippocampus in mild cognitive impairment and early alzheimer's disease. |
2021-02-10 |
2023-08-13 |
Not clear |
| Wei-Ti Hsu, Yi-Hung Chen, Han-Bin Yang, Jaung-Geng Lin, Shih-Ya Hun. Electroacupuncture Improves Motor Symptoms of Parkinson's Disease and Promotes Neuronal Autophagy Activity in Mouse Brain. The American journal of Chinese medicine. vol 48. issue 7. 2021-02-09. PMID:33202151. |
we report that ea improves pd motor symptoms in mice and enhances (1) autophagy initiation (increased beclin 1), (2) autophagosome biogenesis (increased atg5, atg7, atg9a, atg12, atg16l, atg3, and lc3-ii), (3) autophagy flux/substrate degradation (decreased p62), and (4) mitophagy (increased pink1 and dj-1) in neurons of the substantia nigra, striatum, hippocampus, and cortex (affected brain areas of pd, huntington disease, and alzheimer's disease). |
2021-02-09 |
2023-08-13 |
mouse |
| Zhen Qiang Zhang, Christian Hölsche. GIP has neuroprotective effects in Alzheimer and Parkinson's disease models. Peptides. vol 125. 2021-02-08. PMID:31705913. |
in alzheimer's disease models, memory is rescued, synapse numbers and synaptic plasticity in the hippocampus is normalized, amyloid plaque load and the chronic inflammation is reduced. |
2021-02-08 |
2023-08-13 |
mouse |
| Shea J Andrews, Brian Fulton-Howard, Paul O'Reilly, Edoardo Marcora, Alison M Goat. Causal Associations Between Modifiable Risk Factors and the Alzheimer's Phenome. Annals of neurology. vol 89. issue 1. 2021-02-02. PMID:32996171. |
the purpose of this study was to infer causal relationships between 22 previously reported risk factors for alzheimer's disease (ad) and the "ad phenome": ad, ad age of onset (aaos), hippocampal volume, cortical surface area and thickness, cerebrospinal fluid (csf) levels of amyloid-β (aβ |
2021-02-02 |
2023-08-13 |
Not clear |
| Chuan He, Zhong-Sheng Huang, Hong-Ru Chen, Chao-Chao Yu, Xue-Song Wang, Tao Jiang, Li-Hong Kon. [Effect of pretreatment of acupuncture on learning-memory ability and related protein of NLRP3 inflammasome in hippocampus in Alzheimer's disease like rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 12. 2021-02-01. PMID:33415876. |
[effect of pretreatment of acupuncture on learning-memory ability and related protein of nlrp3 inflammasome in hippocampus in alzheimer's disease like rats]. |
2021-02-01 |
2023-08-13 |
rat |
| Chuan He, Zhong-Sheng Huang, Hong-Ru Chen, Chao-Chao Yu, Xue-Song Wang, Tao Jiang, Li-Hong Kon. [Effect of pretreatment of acupuncture on learning-memory ability and related protein of NLRP3 inflammasome in hippocampus in Alzheimer's disease like rats]. Zhongguo zhen jiu = Chinese acupuncture & moxibustion. vol 40. issue 12. 2021-02-01. PMID:33415876. |
to observe the effect of pretreatment of acupuncture on the expression of nucleotide-binding oligomerization domain-like receptor 3(nlrp3), caspase-1, interleukin1β(il-1β) and the number of activated microglia (mg) in the hippocampus in alzheimer's disease (ad) like rats, so as to explore the mechanism of pretreatment of acupuncture in preventing and treating ad. |
2021-02-01 |
2023-08-13 |
rat |
| Negar Mehri, Rasool Haddadi, Maziar Ganji, Siamak Shahidi, Sara Soleimani Asl, Masoume Taheri Azandariani, Akram Ranjba. Effects of vitamin D in an animal model of Alzheimer's disease: behavioral assessment with biochemical investigation of Hippocampus and serum. Metabolic brain disease. vol 35. issue 2. 2021-01-29. PMID:31853828. |
effects of vitamin d in an animal model of alzheimer's disease: behavioral assessment with biochemical investigation of hippocampus and serum. |
2021-01-29 |
2023-08-13 |
rat |
| b' Kilian Hett, Vinh-Thong Ta, Gwena\\xc3\\xablle Catheline, Thomas Tourdias, Jos\\xc3\\xa9 V Manj\\xc3\\xb3n, Pierrick Coup\\xc3\\xa. Author Correction: Multimodal hippocampal subfield grading for Alzheimer\'s disease classification. Scientific reports. vol 10. issue 1. 2021-01-27. PMID:32606432.' |
author correction: multimodal hippocampal subfield grading for alzheimer's disease classification. |
2021-01-27 |
2023-08-13 |
Not clear |
| Amanda K Engstrom, Alicia C Walker, Rohitha A Moudgal, Dexter A Myrick, Stephanie M Kyle, Yu Bai, M Jordan Rowley, David J Kat. The inhibition of LSD1 via sequestration contributes to tau-mediated neurodegeneration. Proceedings of the National Academy of Sciences of the United States of America. vol 117. issue 46. 2021-01-25. PMID:33139560. |
previously, our laboratory implicated the histone demethylase lsd1 in tau-induced neurodegeneration by showing that lsd1 localizes to pathological tau aggregates in alzheimer's disease cases, and that it is continuously required for the survival of hippocampal and cortical neurons in mice. |
2021-01-25 |
2023-08-13 |
mouse |
| Md Habibur Rahman, Rokeya Akter, Tanima Bhattacharya, Mohamed M Abdel-Daim, Saad Alkahtani, Mohammed W Arafah, Norah S Al-Johani, Norah M Alhoshani, Nora Alkeraishan, Alhanof Alhenaky, Omar H Abd-Elkader, Hesham R El-Seedi, Deepak Kaushik, Vineet Mitta. Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease. Frontiers in pharmacology. vol 11. 2021-01-19. PMID:33456444. |
alzheimer's disease (ad) is a progressive cortex and hippocampal neurodegenerative disease which ultimately causes cognitively impaired decline in patients. |
2021-01-19 |
2023-08-13 |
Not clear |
| Lei Xu, Haixiang Yu, Hongbin Sun, Bang Hu, Yi Gen. Dietary Melatonin Therapy Alleviates the Lamina Cribrosa Damages in Patients with Mild Cognitive Impairments: A Double-Blinded, Randomized Controlled Study. Medical science monitor : international medical journal of experimental and clinical research. vol 26. 2021-01-19. PMID:32376818. |
background alzheimer's disease (ad) is a degenerative disease that is characterized by massive neuron devastations in the hippocampus and cortex. |
2021-01-19 |
2023-08-13 |
Not clear |
| Hong-He Xiao, Ming-Bo Zhang, Jun-Ting Xu, Yan Deng, Ning Li, Peng Gao, Yan Li, Liang Kong, Wan-Yi Li, Ji-Cong Chen, Hong-Yan Li, Guo-Shun Shan, He Tai, Jing-Xian Yan. Icarisid II promotes proliferation and neuronal differentiation of neural stem cells via activating Wnt/β-catenin signaling pathway. Phytotherapy research : PTR. 2021-01-17. PMID:33455039. |
mobilization of hippocampal neurogenesis has been regarded as a promising therapeutic approach to restore injured neurons in neurodegenerative diseases including alzheimer's disease (ad). |
2021-01-17 |
2023-08-13 |
human |
| Fengjin Hao, Yueqin Fen. Cannabidiol (CBD) enhanced the hippocampal immune response and autophagy of APP/PS1 Alzheimer's mice uncovered by RNA-seq. Life sciences. vol 264. 2021-01-15. PMID:33096116. |
cannabidiol (cbd) enhanced the hippocampal immune response and autophagy of app/ps1 alzheimer's mice uncovered by rna-seq. |
2021-01-15 |
2023-08-13 |
mouse |
| Masoomeh Nazifi, Shahrbanoo Oryan, Delaram Eslimi Esfahani, Manoochehr Ashrafpoo. The functional effects of piperine and piperine plus donepezil on hippocampal synaptic plasticity impairment in rat model of Alzheimer's disease. Life sciences. vol 265. 2021-01-13. PMID:33242524. |
the functional effects of piperine and piperine plus donepezil on hippocampal synaptic plasticity impairment in rat model of alzheimer's disease. |
2021-01-13 |
2023-08-13 |
rat |