| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P T Francis, D M Bowen, S L Lowe, D Neary, D M Mann, J S Snowde. Somatostatin content and release measured in cerebral biopsies from demented patients. Journal of the neurological sciences. vol 78. issue 1. 1987-06-08. PMID:3572446. |
the k+-stimulated release of endogenous slir from tissue prisms ('mini-slices') prepared from neocortex obtained at diagnostic craniotomy from alzheimer patients was not below the control values. |
1987-06-08 |
2023-08-11 |
Not clear |
| H Braak, E Braa. Ratio of pyramidal cells versus non-pyramidal cells in the human frontal isocortex and changes in ratio with ageing and Alzheimer's disease. Progress in brain research. vol 70. 1987-06-08. PMID:3575748. |
ratio of pyramidal cells versus non-pyramidal cells in the human frontal isocortex and changes in ratio with ageing and alzheimer's disease. |
1987-06-08 |
2023-08-11 |
human |
| R D Terry, L A Hansen, R DeTeresa, P Davies, H Tobias, R Katzma. Senile dementia of the Alzheimer type without neocortical neurofibrillary tangles. Journal of neuropathology and experimental neurology. vol 46. issue 3. 1987-05-19. PMID:2881985. |
senile dementia of the alzheimer type (sdat) is typified pathologically by neuritic plaques (np) and neurofibrillary tangles (nft) in the neocortex and hippocampus. |
1987-05-19 |
2023-08-11 |
Not clear |
| M F Mazurek, M F Beal, E D Bird, J B Marti. Vasopressin in Alzheimer's disease: a study of postmortem brain concentrations. Annals of neurology. vol 20. issue 6. 1987-02-26. PMID:3813496. |
alzheimer brains had either normal or slightly increased avp levels in the neocortex, which does not have avp cell bodies. |
1987-02-26 |
2023-08-11 |
human |
| A Delacourte, A Defosse. Alzheimer's disease: Tau proteins, the promoting factors of microtubule assembly, are major components of paired helical filaments. Journal of the neurological sciences. vol 76. issue 2-3. 1987-02-05. PMID:3098926. |
this antiserum stains specifically neurofibrillary tangles (nft) at the light-microscopic level and phf at the electron-microscopic level in sections of alzheimer neocortex and hippocampus. |
1987-02-05 |
2023-08-11 |
rabbit |
| J J Sloper, R O Barnard, R P Eglin, T P Powel. Abnormal tubular structures associated with the granular endoplasmic reticulum of neocortical neurons in a biopsy from a patient with Alzheimer's disease. Neuropathology and applied neurobiology. vol 12. issue 5. 1987-01-15. PMID:3785572. |
the electron microscope has been used to examine a diagnostic biopsy of frontal neocortex which showed the light microscopic features of alzheimer's disease. |
1987-01-15 |
2023-08-11 |
Not clear |
| J G Guillemette, L Wong, D R Crapper McLachlan, P N Lewi. Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain. Journal of neurochemistry. vol 47. issue 3. 1986-09-25. PMID:2426413. |
a detailed comparative study of rna transcripts isolated from the neocortex of control and alzheimer postmortem brains was made to determine whether morphological changes in the chromatin of alzheimer neurons and glia, which we reported earlier, are accompanied by changes in the products of transcription. |
1986-09-25 |
2023-08-11 |
human |
| J G Guillemette, L Wong, D R Crapper McLachlan, P N Lewi. Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain. Journal of neurochemistry. vol 47. issue 3. 1986-09-25. PMID:2426413. |
our results reveal that the yields of total rna, unadenylated mrna, and poly(a) tail lengths from alzheimer neocortex samples do not differ significantly from those of control and non-alzheimer dementia neocortex. |
1986-09-25 |
2023-08-11 |
human |
| J G Guillemette, L Wong, D R Crapper McLachlan, P N Lewi. Characterization of messenger RNA from the cerebral cortex of control and Alzheimer-afflicted brain. Journal of neurochemistry. vol 47. issue 3. 1986-09-25. PMID:2426413. |
the direct correlation of reduced poly(a)+ mrna and chromatin condensation in alzheimer neocortex suggests a cause-and-effect relationship. |
1986-09-25 |
2023-08-11 |
human |
| D P Perl, W W Pendlebur. Neuropathology of dementia. Neurologic clinics. vol 4. issue 2. 1986-06-30. PMID:2940454. |
the most important, alzheimer's disease, is characterized by the widespread development of neurofibrillary tangles and senile or neuritic plaques in the hippocampus and neocortex. |
1986-06-30 |
2023-08-11 |
Not clear |
| S Nakamura, S R Vincen. Somatostatin- and neuropeptide Y-immunoreactive neurons in the neocortex in senile dementia of Alzheimer's type. Brain research. vol 370. issue 1. 1986-06-27. PMID:2871890. |
somatostatin- and neuropeptide y-immunoreactive neurons in the neocortex in senile dementia of alzheimer's type. |
1986-06-27 |
2023-08-11 |
human |
| J J Sloper, T P Powell, R O Barnard, R P Egli. Ultrastructural abnormality in Alzheimer neocortex. Lancet (London, England). vol 1. issue 8479. 1986-04-02. PMID:2869256. |
ultrastructural abnormality in alzheimer neocortex. |
1986-04-02 |
2023-08-11 |
Not clear |
| S B Dunnett, G Toniolo, A Fine, C N Ryan, A Björklund, S D Iverse. Transplantation of embryonic ventral forebrain neurons to the neocortex of rats with lesions of nucleus basalis magnocellularis--II. Sensorimotor and learning impairments. Neuroscience. vol 16. issue 4. 1986-03-31. PMID:4094694. |
the cholinergic projection from the nucleus basalis magnocellularis to the neocortex has been implicated in normal memory function and in the dementia of alzheimer's disease. |
1986-03-31 |
2023-08-11 |
rat |
| E B De Souza, P J Whitehouse, M J Kuhar, D L Price, W W Val. Reciprocal changes in corticotropin-releasing factor (CRF)-like immunoreactivity and CRF receptors in cerebral cortex of Alzheimer's disease. Nature. vol 319. issue 6054. 1986-03-20. PMID:3003585. |
alzheimer's disease is a progressive degenerative disease of the nervous system characterized neuropathologically by the presence of senile plaques and neurofibrillary tangles in amygdala, hippocampus and neocortex. |
1986-03-20 |
2023-08-11 |
Not clear |
| D M Armstrong, S LeRoy, D Shields, R D Terr. Somatostatin-like immunoreactivity within neuritic plaques. Brain research. vol 338. issue 1. 1985-10-03. PMID:2862952. |
alzheimer's disease or senile dementia of the alzheimer type (sdat) is a progressive neurodegenerative disease that is characterized pathologically by two types of microscopic lesions in the neocortex: the neurofibrillary tangle and neuritic plaque. |
1985-10-03 |
2023-08-11 |
Not clear |
| A Fine, S B Dunnett, A Björklund, S D Iverse. Cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 15. 1985-09-06. PMID:3860857. |
cholinergic ventral forebrain grafts into the neocortex improve passive avoidance memory in a rat model of alzheimer disease. |
1985-09-06 |
2023-08-11 |
rat |
| F Koukoli. [Diagnosis of Alzheimer's disease in the aged. II. Quantitative aspects]. Ceskoslovenska patologie. vol 21. issue 2. 1985-08-27. PMID:4017029. |
subclinical forms of alzheimer's disease in old age can be supposed because of the finding of plaques in neocortex and neuronal decrease in nucleus basalis in several cases of the control group. |
1985-08-27 |
2023-08-11 |
Not clear |
| R C Pearson, M M Esiri, R W Hiorns, G K Wilcock, T P Powel. Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 13. 1985-08-14. PMID:3859874. |
anatomical correlates of the distribution of the pathological changes in the neocortex in alzheimer disease. |
1985-08-14 |
2023-08-11 |
Not clear |
| R C Pearson, M M Esiri, R W Hiorns, G K Wilcock, T P Powel. Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 13. 1985-08-14. PMID:3859874. |
the numbers and distribution of the neurofibrillary tangles and neuritic plaques have been determined in several areas of the neocortex in brains affected by various degrees of severity of alzheimer disease. |
1985-08-14 |
2023-08-11 |
Not clear |
| R C Pearson, M M Esiri, R W Hiorns, G K Wilcock, T P Powel. Anatomical correlates of the distribution of the pathological changes in the neocortex in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America. vol 82. issue 13. 1985-08-14. PMID:3859874. |
these data on the severity of the pathological involvement in different areas of the neocortex and the laminar distribution and the clustering of the tangles support the suggestion that the pathological changes in alzheimer disease affect regions that are interconnected by well-defined groups of connections and that the disease process may extend along the connecting fibers. |
1985-08-14 |
2023-08-11 |
Not clear |