| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S Jenni-Eiermann, H P von Hahn, C G Honegger, J Ulric. Studies on neurotransmitter binding in senile dementia. Comparison of Alzheimer's and mixed vascular-Alzheimer's dementias. Gerontology. vol 30. issue 6. 1985-03-11. PMID:6151534. |
binding of 3h-labeled agonists and antagonists to muscarinic-cholinergic, alpha- and beta-adrenergic, dopaminergic, serotoninergic, and opiate receptors was studied in four regions of the neocortex and in hippocampus, thalamus, putamen, and caudatus in autoptic material from patients with senile dementia of alzheimer type and of mixed vascular-alzheimer pathogenesis. |
1985-03-11 |
2023-08-12 |
Not clear |
| D G Brownstein, E A Johnson, A L Smit. Spontaneous Reye's-like syndrome in BALB/cByJ mice. Laboratory investigation; a journal of technical methods and pathology. vol 51. issue 4. 1984-11-13. PMID:6482384. |
necropsy findings included swollen, diffusely pale yellow livers with panlobular microvesicular fatty change, pale renal cortices with epithelial fat droplets of the proximal convoluted tubules, and alzheimer type ii astrocytosis of the neocortex, corpus striatum, hippocampus, and thalamus. |
1984-11-13 |
2023-08-12 |
mouse |
| S M Sagar, M F Beal, P E Marshall, D M Landis, J B Marti. Implications of neuropeptides in neurological diseases. Peptides. vol 5 Suppl 1. 1984-11-09. PMID:6207511. |
somatostatin concentration is reduced in the hippocampus and neocortex of patients dying with alzheimer's type dementia. |
1984-11-09 |
2023-08-12 |
human |
| D R McLachlan, P N Lewis, W J Lukiw, A Sima, C Bergeron, U De Bon. Chromatin structure in dementia. Annals of neurology. vol 15. issue 4. 1984-07-27. PMID:6742779. |
nuclei extracted from neocortex of patients with alzheimer's disease and treated with micrococcal nuclease release a population of dinucleosomes that contain an increase in the linker histones h1o and h1oo . |
1984-07-27 |
2023-08-12 |
human |
| R J Rylett, M J Ball, E H Colhou. Evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with Alzheimer's disease. Brain research. vol 289. issue 1-2. 1984-03-12. PMID:6661641. |
evidence for high affinity choline transport in synaptosomes prepared from hippocampus and neocortex of patients with alzheimer's disease. |
1984-03-12 |
2023-08-12 |
human |
| P Averbac. Dense microspheres in normal human brain. Acta neuropathologica. vol 61. issue 2. 1983-12-17. PMID:6637399. |
the frequency of dms in random samples of temporal neocortex was compared in 96 normals, 10 cases of alzheimer's disease, 10 cases of parkinson's disease, 10 cases of schizophrenia, and 20 cases of other nervous diseases. |
1983-12-17 |
2023-08-12 |
human |
| N R Sims, D M Bowen, D Neary, A N Daviso. Metabolic processes in Alzheimer's disease: adenine nucleotide content and production of 14CO2 from [U-14C]glucose in vitro in human neocortex. Journal of neurochemistry. vol 41. issue 5. 1983-11-23. PMID:6413656. |
metabolic processes in alzheimer's disease: adenine nucleotide content and production of 14co2 from [u-14c]glucose in vitro in human neocortex. |
1983-11-23 |
2023-08-12 |
human |
| N R Sims, D M Bowen, D Neary, A N Daviso. Metabolic processes in Alzheimer's disease: adenine nucleotide content and production of 14CO2 from [U-14C]glucose in vitro in human neocortex. Journal of neurochemistry. vol 41. issue 5. 1983-11-23. PMID:6413656. |
samples of neocortex removed at diagnostic craniotomy from patients with alzheimer's disease and incubated in vitro showed an increased production of 14co2 from [u-14c]glucose compared with neurosurgical controls. |
1983-11-23 |
2023-08-12 |
human |
| D M Bowen, S J Allen, J S Benton, M J Goodhardt, E A Haan, A M Palmer, N R Sims, C C Smith, J A Spillane, M M Esiri, D Neary, J S Snowdon, G K Wilcock, A N Daviso. Biochemical assessment of serotonergic and cholinergic dysfunction and cerebral atrophy in Alzheimer's disease. Journal of neurochemistry. vol 41. issue 1. 1983-08-11. PMID:6306169. |
markers of serotonin synapses in entire temporal lobe and frontal and temporal neocortex were examined for changes in alzheimer's disease by use of both neurosurgical and autopsy samples. |
1983-08-11 |
2023-08-12 |
Not clear |
| C C Smith, D M Bowen, N R Sims, D Neary, A N Daviso. Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease. Brain research. vol 264. issue 1. 1983-07-29. PMID:6133580. |
amino acid release from biopsy samples of temporal neocortex from patients with alzheimer's disease. |
1983-07-29 |
2023-08-12 |
Not clear |
| C C Smith, D M Bowen, N R Sims, D Neary, A N Daviso. Amino acid release from biopsy samples of temporal neocortex from patients with Alzheimer's disease. Brain research. vol 264. issue 1. 1983-07-29. PMID:6133580. |
tissue prisms prepared from neurosurgical samples of temporal neocortex of alzheimer and control patients, upon depolarization preferentially released aspartate, glutamate and gamma-aminobutyrate (gaba). |
1983-07-29 |
2023-08-12 |
Not clear |
| K L Marek, D M Bowen, N R Sims, A N Daviso. Stimulation of acetylcholine synthesis by blockade of presynaptic muscarinic inhibitory autoreceptors: observations in rat and human brain preparations and comparison with the effect of choline. Life sciences. vol 30. issue 18. 1982-07-19. PMID:7078351. |
ach synthesis is reduced to 50% of control in neocortex from alzheimer patients so none of the antimuscarinics tested seem to be potentially capable of appreciably reversing this deficit. |
1982-07-19 |
2023-08-12 |
human |
| P Michaud, J Gaches, J F Fonci. [Critical follow-up study of subjects with senile plaques: neuropathological, clinical, and electroencephalographic data (author's transl)]. Revue d'electroencephalographie et de neurophysiologie clinique. vol 10. issue 3. 1982-01-20. PMID:7302324. |
frontal isocortex biopsy or operative specimens exhibited senile plaques in 25 patients aged 40 to 73 years, association with alzheimer's "neurofibrillary degeneration" in 20 of them. |
1982-01-20 |
2023-08-12 |
human |
| G C McIntosh, H D Jameson, W R Markesber. Huntington disease associated with Alzheimer disease. Annals of neurology. vol 3. issue 6. 1978-09-25. PMID:150253. |
the pathological findings were those of huntington disease (atrophy with neuronal loss and astrocytosis in the neostriatum) and alzheimer disease (neuronal loss with numerous senile plaques and neurofibrillary tangles in the neocortex). |
1978-09-25 |
2023-08-11 |
Not clear |
| R C Go, A B Todorov, R C Elston, J Constantinidi. The malignancy of dementias. Annals of neurology. vol 3. issue 6. 1978-09-25. PMID:677821. |
among patients classed as having alzheimer disease, the longest survival times were in those with neurofibrillary tangles involving the neocortex, while those lacking this anatomical abnormality had the shortest survival times. |
1978-09-25 |
2023-08-11 |
Not clear |