| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Santino Gaudio, Gull Rukh, Vincenzo Di Ciommo, Samuel Berkins, Lyle Wiemerslage, Helgi B Schiöt. Higher fresh fruit intake relates to larger grey matter volumes in areas involved in dementia and depression: A UK Biobank study. NeuroImage. vol 283. 2023-11-02. PMID:37918179. |
in particular, fresh fruit intake may have a protective role in specific cortical areas such as the hippocampus, areas robustly involved in the pathophysiology of dementia and depression. |
2023-11-02 |
2023-11-08 |
human |
| Rohit Malik, Sunishtha Kalra, Pooja, Govind Singh, Meenu, Vinod Gahlot, Anjali Kajal, Rimp. Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent. Brain research. 2023-10-04. PMID:37793605. |
overcome scopolamine-induced alzheimer's type dementia in mice by activating the cholinergic system, anti-oxidant and protection of neuronal death in the brain (hippocampus region). |
2023-10-04 |
2023-10-07 |
mouse |
| Jun Yup Lee, Dylan J Harney, Jonathan D Teo, John B Kwok, Greg T Sutherland, Mark Larance, Anthony S Do. The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus. Molecular neurodegeneration. vol 18. issue 1. 2023-09-19. PMID:37726834. |
the major tmem106b dementia risk allele affects tmem106b protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus. |
2023-09-19 |
2023-10-07 |
human |
| Jun Yup Lee, Dylan J Harney, Jonathan D Teo, John B Kwok, Greg T Sutherland, Mark Larance, Anthony S Do. The major TMEM106B dementia risk allele affects TMEM106B protein levels, fibril formation, and myelin lipid homeostasis in the ageing human hippocampus. Molecular neurodegeneration. vol 18. issue 1. 2023-09-19. PMID:37726834. |
this study aimed to determine how ageing and major genetic risk factors for dementia affect the hippocampal proteome and lipidome of neurologically-normal humans over the age of 65. |
2023-09-19 |
2023-10-07 |
human |
| Mohammad Yazdan Panah, Yousef Mokary, Sangam Shah, Sangharsha Thapa, Swati Chand, Vahid Shaygannejad, Omid Mirmosayye. Comparing the hippocampal volumetric atrophy between demented and nondemented individuals with Parkinson's disease: A systematic review and meta-analysis. Health science reports. vol 6. issue 9. 2023-09-13. PMID:37701357. |
as such, we designed this study to compare the hippocampal volumes of pd patients with dementia (pdd) versus pd without dementia. |
2023-09-13 |
2023-10-07 |
Not clear |
| Christopher G Schwarz, Walter K Kremers, Stephen D Weigand, Carl M Prakaashana, Matthew L Senjem, Scott A Przybelski, Val J Lowe, Jeffrey L Gunter, Kejal Kantarci, Prashanthi Vemuri, Jonathan Graff-Radford, Ronald C Petersen, David S Knopman, Clifford R Jac. Effects of de-facing software mri_reface on utility of imaging biomarkers used in Alzheimer's disease research. NeuroImage. Clinical. vol 40. 2023-09-13. PMID:37703605. |
we created a retrospective sample of participants from three age- and sex-matched clinical groups (cognitively unimpaired, mild cognitive impairment, and ad dementia, and we performed region- and voxel-wise analyses of: hippocampal volume (n), white matter hyperintensity volume (v), amyloid pet (a), and tau pet (t) measures, each from multiple software pipelines, on their ability to separate cognitively defined groups and their degrees of correlation with age and clinical dementia rating (cdr)-sum of boxes (cdr-sb). |
2023-09-13 |
2023-10-07 |
human |
| Noor Ali, Rohab Sohail, Syeda Rabab Jaffer, Sadia Siddique, Berfin Kaya, Inioluwa Atowoju, Alizay Imran, Whitney Wright, Spandana Pamulapati, Faiza Choudhry, Anum Akbar, Uzzam Ahmed Khawaj. The Role of Estrogen Therapy as a Protective Factor for Alzheimer's Disease and Dementia in Postmenopausal Women: A Comprehensive Review of the Literature. Cureus. vol 15. issue 8. 2023-09-08. PMID:37680393. |
estrogen prevents dementia by augmenting hippocampal and prefrontal cortex function, reducing neuroinflammation, preventing degradation of estrogen receptors, decreasing oxidative damage to the brain, and increasing cholinergic and serotonergic function. |
2023-09-08 |
2023-10-07 |
Not clear |
| Hong Zhuang, Qian Li, Congli Sun, Dan Xu, Guangming Gan, Chenchen Zhang, Chen Chen, Yang Yuan, Linchen Liu, Yu Xiao, Xiuting Yao, Conghui Wang, Xiaoming Kang, Chenxi Yang, Jingyi Zhao, Wenhao Chen, Jiatang Wang, Jinyu Li, Caichen Luo, Jie Wang, Xirui Jia, Zhehao Yu, Lijie Li. Voluntary wheel exercise ameliorates cognitive impairment, hippocampal neurodegeneration and microglial abnormalities preceded by demyelination in a male mouse model of noise-induced hearing loss. Brain, behavior, and immunity. 2023-09-08. PMID:37683962. |
our results indicated that accelerated cognitive deterioration and hippocampal neuroplastic decline following nihl are most likely driven by the maladaptive response of hippocampal microglia to myelin damage secondary to hearing loss, and we also demonstrated the potential of voluntary physical exercise as a promising and cost-effective strategy to alleviate the detrimental impact of aphl on cognitive function and thus curtail the high and continuously increasing global burden of dementia. |
2023-09-08 |
2023-10-07 |
mouse |
| Janice X Li, Hannah L Nguyen, Tianchen Qian, Davis C Woodworth, S Ahmad Sajjad. Longitudinal hippocampal atrophy in hippocampal sclerosis of aging. Aging brain. vol 4. 2023-08-28. PMID:37635712. |
hippocampal sclerosis of aging (hs-a) is a common degenerative neuropathology in older individuals and is associated with dementia. |
2023-08-28 |
2023-09-07 |
human |
| Janice X Li, Hannah L Nguyen, Tianchen Qian, Davis C Woodworth, S Ahmad Sajjad. Longitudinal hippocampal atrophy in hippocampal sclerosis of aging. Aging brain. vol 4. 2023-08-28. PMID:37635712. |
we found that participants with hs-a had lower hippocampal volumes compared to the other groups, and this atrophy preceded the onset of dementia. |
2023-08-28 |
2023-09-07 |
human |
| Janice X Li, Hannah L Nguyen, Tianchen Qian, Davis C Woodworth, S Ahmad Sajjad. Longitudinal hippocampal atrophy in hippocampal sclerosis of aging. Aging brain. vol 4. 2023-08-28. PMID:37635712. |
together, these results suggest that the disproportionate hippocampal atrophy seen in hs-a may begin early prior to dementia. |
2023-08-28 |
2023-09-07 |
human |
| Grace Minogue, Allegra Kawles, Antonia Zouridakis, Rachel Keszycki, Alyssa Macomber, Vivienne Lubbat, Nathan Gill, Qinwen Mao, Margaret E Flanagan, Hui Zhang, Rudolph Castellani, Eileen H Bigio, M-Marsel Mesulam, Changiz Geula, Tamar Gefe. Distinct Patterns of Hippocampal Pathology in Alzheimer's Disease with TDP-43. Annals of neurology. 2023-08-18. PMID:37592884. |
here, we investigated neuronal integrity and pathologic burden of tdp-43 and tau along the well-charted trisynaptic hippocampal circuit [dentate gyrus (dg), ca3, and ca1] in participants with amnestic dementia due to ad/tdp, amnestic dementia due to ad alone, or non-amnestic dementia due to tdp-43 proteinopathy associated with frontotemporal lobar degeneration (ftld-tdp). |
2023-08-18 |
2023-09-07 |
human |
| Lon R White, Maria M Corrada, Claudia H Kawas, Brenna A Cholerton, Steve E Edland, Margaret E Flanagan, Thomas J Montin. Neuropathologic Changes of Alzheimer's Disease and Related Dementias: Relevance to Future Prevention. Journal of Alzheimer's disease : JAD. 2023-07-31. PMID:37522210. |
decedents with late-life dementia are often found at autopsy to have vascular pathology, cortical lewy bodies, hippocampal sclerosis, and/or tdp-43 encephalopathy alone or with concurrent alzheimer's disease (ad) lesions. |
2023-07-31 |
2023-08-14 |
Not clear |
| Carmina C Warth Perez Arias, Ivan Silbern, Lucas Caldi Gomes, Hannes Wartmann, Vivian Dambeck, Jonas Fanz, Lisa Neuenroth, Mathias Bähr, Tiago F Outeiro, Stefan Bonn, Christine Stadelmann-Nessler, Silvio O Rizzoli, Christof Lenz, Henning Urlaub, Paul Lingo. Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease. Journal of neurochemistry. 2023-07-29. PMID:37515330. |
in this study, we analyzed pd-associated alterations in the hippocampus of pd patients, since this brain region is strongly affected by pd dementia. |
2023-07-29 |
2023-08-14 |
human |
| Mélissa Gentreau, Jerome J Maller, Chantal Meslin, Fabienne Cyprien, Jorge Lopez-Castroman, Sylvaine Arter. Is Hippocampal Volume a Relevant Early Marker of Dementia? The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry. 2023-07-02. PMID:37394314. |
is hippocampal volume a relevant early marker of dementia? |
2023-07-02 |
2023-08-14 |
human |
| Diana Ortega-Cruz, Juan Eugenio Iglesias, Alberto Rabano, Bryan A Strang. Hippocampal sclerosis of aging at post-mortem is evident on MRI more than a decade prior. Alzheimer's & dementia : the journal of the Alzheimer's Association. 2023-06-27. PMID:37366342. |
hippocampal sclerosis of aging (hs) is an important component of combined dementia neuropathology. |
2023-06-27 |
2023-08-14 |
Not clear |
| Chenxi Li, Junyan Guo, Yining Zhao, Kaili Sun, Zeinab Abdelrahman, Xingqi Cao, Jingyun Zhang, Zhoutao Zheng, Changzheng Yuan, Huiqian Huang, Yaojing Chen, Zuyun Liu, Zuobing Che. Visit-to-visit HbA1c variability, dementia, and hippocampal atrophy among adults without diabetes. Experimental gerontology. 2023-06-01. PMID:37263368. |
thus, this study aimed to investigate the associations of visit-to-visit hba1c variability with incident dementia and hippocampal volume among middle-aged and older adults without diabetes, providing potential insights into this question. |
2023-06-01 |
2023-08-14 |
Not clear |
| Jafar Sadeghzadeh, Jaber Jafarzadeh, Pezhman Hadinezhad, Ahmad Nazari, Saeedeh Sohrabi, Vali Musazadeh, Ali Barzegar, Parviz Shahab. Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia. International immunopharmacology. vol 120. 2023-05-23. PMID:37220695. |
profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin d3 treatment in the mice model of vascular dementia. |
2023-05-23 |
2023-08-14 |
mouse |
| Jafar Sadeghzadeh, Jaber Jafarzadeh, Pezhman Hadinezhad, Ahmad Nazari, Saeedeh Sohrabi, Vali Musazadeh, Ali Barzegar, Parviz Shahab. Profiling inflammatory mechanisms, hyperphosphorylated tau of hippocampal tissue and spatial memory following vitamin D3 treatment in the mice model of vascular dementia. International immunopharmacology. vol 120. 2023-05-23. PMID:37220695. |
the aim of this study was to investigate the effect of vitamin d3 (vitd3) on inflammatory mechanisms, hyperphosphorylated tau (p-tau) in the hippocampus, and cognitive impairment of the mouse model of vascular dementia (vad). |
2023-05-23 |
2023-08-14 |
mouse |
| Huiqin Zhang, Zuojun Wang, Koon-Ho Chan, Yat-Fung Shea, Chi-Yan Lee, Patrick Ka-Chun Chiu, Peng Cao, Henry Ka-Fung Ma. The Use of Diffusion Kurtosis Imaging for the Differential Diagnosis of Alzheimer's Disease Spectrum. Brain sciences. vol 13. issue 4. 2023-05-16. PMID:37190560. |
these findings suggest that, in the predementia stage (scd and mci), hippocampal microstructural changes are predominant, and the best discriminators are microstructural measurements (left hippocampal mk for scd and right hippocampal md for mci); while in the dementia stage (ad), hippocampal macrostructural alterations are superior, and the best indicator is the macrostructural index (right hippocampal volume). |
2023-05-16 |
2023-08-14 |
Not clear |