| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Vani Jangra, Jeshnu Topl. Can Alzheimer's Disease Be Secondary to Type-2 Diabetes Mellitus? Cureus. vol 14. issue 11. 2022-12-12. PMID:36505102. |
thirdly, several pathological research has also shown that beta-amyloid plaques, hyperphosphorylated tau protein, and brain shrinkage, particularly in the hippocampus, are shared brain lesions between insulin and alzheimer's disease. in light of this, type 2 diabetes mellitus may be viewed as a liability for dementia and alzheimer's disease. |
2022-12-12 |
2023-08-14 |
human |
| Yaru Liu, Zhenyang Yan, Yafei Ren, Woyu Wang, Yinze Ke, Yifan Wang, Rongming Q. Electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the JNK signaling pathway. Acupuncture in medicine : journal of the British Medical Acupuncture Society. 2022-12-09. PMID:36482691. |
electroacupuncture inhibits hippocampal neuronal apoptosis and improves cognitive dysfunction in mice with vascular dementia via the jnk signaling pathway. |
2022-12-09 |
2023-08-14 |
mouse |
| David A Cinalli, Sarah J Cohen, Mariah Calubag, Goksu Oz, Lylybell Zhou, Robert W Stackma. DREADD-inactivation of dorsal CA1 pyramidal neurons in mice impairs retrieval of object and spatial memories. Hippocampus. 2022-12-05. PMID:36468186. |
hippocampal damage in humans has been linked to amnesia and memory loss, characteristic of alzheimer's disease and other dementias. |
2022-12-05 |
2023-08-14 |
mouse |
| Kumar Surya, Nivethitha Manickam, Kesavan Swaminathan Jayachandran, Mahesh Kandasamy, Muthuswamy Anusuyadev. Resveratrol Mediated Regulation of Hippocampal Neuroregenerative Plasticity via SIRT1 Pathway in Synergy with Wnt Signaling: Neurotherapeutic Implications to Mitigate Memory Loss in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. 2022-12-04. PMID:36463442. |
besides, impaired adult neurogenesis in the hippocampus has experimentally been realized as an underlying cause of dementia regardless of neurodegeneration. |
2022-12-04 |
2023-08-14 |
Not clear |
| Yang Deng, Junqing Zou, Ye Hong, Qiang Peng, Xinxin Fu, Rui Duan, Jie Chen, Xiangliang Che. Higher Circulating Trimethylamine N-Oxide Aggravates Cognitive Impairment Probably via Downregulating Hippocampal SIRT1 in Vascular Dementia Rats. Cells. vol 11. issue 22. 2022-11-26. PMID:36429082. |
higher circulating trimethylamine n-oxide aggravates cognitive impairment probably via downregulating hippocampal sirt1 in vascular dementia rats. |
2022-11-26 |
2023-08-14 |
rat |
| Kausalia Vijayaragavan, Bryan J Cannon, Dmitry Tebaykin, Marc Bossé, Alex Baranski, J P Oliveria, Syed A Bukhari, Dunja Mrdjen, M Ryan Corces, Erin F McCaffrey, Noah F Greenwald, Yari Sigal, Diana Marquez, Zumana Khair, Trevor Bruce, Mako Goldston, Anusha Bharadwaj, Kathleen S Montine, R Michael Angelo, Thomas J Montine, Sean C Bendal. Single-cell spatial proteomic imaging for human neuropathology. Acta neuropathologica communications. vol 10. issue 1. 2022-11-05. PMID:36333818. |
mibi facilitated simultaneous, quantitative imaging of 36 proteins on archival human hippocampus from individuals spanning cognitively normal to dementia. |
2022-11-05 |
2023-08-14 |
human |
| Chang Deng, Ying-Jie Zou, Hong Zhang, Dan-Feng Chen, Rong-Rong Qiu, Ya-Yu Xu, Dan Xiong, Jie Ta. [Effects of electroacupuncture on the blood-brain-barrier and proinflammatory cytokine IL-1β and IL-18 in the hippocampus of rats with vascular dementia]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 10. 2022-10-27. PMID:36301165. |
[effects of electroacupuncture on the blood-brain-barrier and proinflammatory cytokine il-1β and il-18 in the hippocampus of rats with vascular dementia]. |
2022-10-27 |
2023-08-14 |
rat |
| Chang Deng, Ying-Jie Zou, Hong Zhang, Dan-Feng Chen, Rong-Rong Qiu, Ya-Yu Xu, Dan Xiong, Jie Ta. [Effects of electroacupuncture on the blood-brain-barrier and proinflammatory cytokine IL-1β and IL-18 in the hippocampus of rats with vascular dementia]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 10. 2022-10-27. PMID:36301165. |
to observe the effect of electroacupuncture (ea) on blood-brain barrier (bbb) permeability and proinflammatory cytokines interleukin-1β (il-1β) and interleukin-18 (il-18) in the hippocampus of vascular dementia (vd) rats, so as to explore the mechanism of ea on treatment of vd. |
2022-10-27 |
2023-08-14 |
rat |
| Pengwei Wang, Senlin Mao, Tingting Yi, Lihua Wan. LncRNA MALAT1 Targets miR-9-3p to Upregulate SAP97 in the Hippocampus of Mice with Vascular Dementia. Biochemical genetics. 2022-10-13. PMID:36227424. |
lncrna malat1 targets mir-9-3p to upregulate sap97 in the hippocampus of mice with vascular dementia. |
2022-10-13 |
2023-08-14 |
mouse |
| Katy Pilarzyk, Latarsha Porcher, William R Capell, Steven D Burbano, Jeff Davis, Janet L Fisher, Nicole Gorny, Siena Petrolle, Michy P Kell. Conserved age-related increases in hippocampal PDE11A4 cause unexpected proteinopathies and cognitive decline of social associative memories. Aging cell. 2022-09-08. PMID:36073342. |
here, we found that both aging and traumatic brain injury-associated dementia increased the expression of the camp/cgmp-degrading enzyme phosphodiesterase 11a (pde11a) in the human hippocampus. |
2022-09-08 |
2023-08-14 |
mouse |
| S Duke Han, Debra A Fleischman, Lei Yu, Victoria Poole, Melissa Lamar, Namhee Kim, Sue E Leurgans, David A Bennett, Konstantinos Arfanakis, Lisa L Barne. Cognitive decline and hippocampal functional connectivity within older Black adults. Human brain mapping. 2022-09-06. PMID:36066181. |
we investigated the association of cognitive decline with whole-brain voxel-wise functional connectivity to the hippocampus, a key brain region functionally implicated in early alzheimer's dementia, in 132 older black adults without dementia participating in the minority aging research study and rush memory and aging project, two longitudinal studies of aging that include harmonized annual cognitive assessments and magnetic resonance imaging brain imaging. |
2022-09-06 |
2023-08-14 |
Not clear |
| Dong Peng, Yi-Xue Wang, Tian-Hua Huang, Dan Luo, Li-Jun Qiao, Qi Wang, Li Guan, Ye-Feng Cai, Shi-Jie Zhan. Ligustilide Improves Cognitive Impairment via Regulating the SIRT1/IRE1 Oxidative medicine and cellular longevity. vol 2022. 2022-08-26. PMID:36017237. |
ligustilide improves cognitive impairment via regulating the sirt1/ire1 vascular dementia (vad), the second cause of dementia, is caused by chronic cerebral hypoperfusion, producing progressive damage to cerebral cortex, hippocampus, and white matter. |
2022-08-26 |
2023-08-14 |
Not clear |
| Jin Zhang, Yu Zhang, Yan Liu, Xiaoyuan Ni. Naringenin Attenuates Cognitive Impairment in a Rat Model of Vascular Dementia by Inhibiting Hippocampal Oxidative Stress and Inflammatory Response and Promoting N-Methyl-D-Aspartate Receptor Signaling Pathway. Neurochemical research. 2022-08-26. PMID:36028734. |
naringenin attenuates cognitive impairment in a rat model of vascular dementia by inhibiting hippocampal oxidative stress and inflammatory response and promoting n-methyl-d-aspartate receptor signaling pathway. |
2022-08-26 |
2023-08-14 |
rat |
| Timo Jan Oberstein, Manuel Alexander Schmidt, Anna Florvaag, Anna Lena Haas, Eva Maria Siegmann, Pauline Olm, Janine Utz, Philipp Spitzer, Arnd Doerfler, Piotr Lewczuk, Johannes Kornhuber, Juan Manuel Male. Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy. Brain : a journal of neurology. 2022-08-16. PMID:35973034. |
long term follow-up of a-t + n ± individuals revealed no evidence that this biomarker constellation was associated with dementia or more severe hippocampal atrophy rates compared to controls. |
2022-08-16 |
2023-08-14 |
human |
| Rômulo Sperduto Dezonne, Cláudia Maria Pereira, Cyro José de Moraes Martins, Virgínia Genelhu de Abreu, Emilio Antonio Francischett. Adiponectin, the adiponectin paradox, and Alzheimer's Disease: Is this association biologically plausible? Metabolic brain disease. 2022-08-03. PMID:35921057. |
metabolic dysfunctions of brain structures such as the hippocampus and cerebral cortex have been implicated as risk factors for dementia. |
2022-08-03 |
2023-08-14 |
Not clear |
| Kichang Kwak, William Stanford, Eran Daya. Identifying the regional substrates predictive of Alzheimer's disease progression through a convolutional neural network model and occlusion. Human brain mapping. 2022-07-29. PMID:35904092. |
we found that the hippocampus, fusiform, and inferior temporal gyri were the strongest predictors of ad dementia progression, in agreement with established staging models. |
2022-07-29 |
2023-08-14 |
human |
| Jia-He Zhang, Takashi Tasaki, Manabu Tsukamoto, Ke-Yong Wang, Kin-Ya Kubo, Kagaku Azum. Deletion of Wnt10a Is Implicated in Hippocampal Neurodegeneration in Mice. Biomedicines. vol 10. issue 7. 2022-07-27. PMID:35884806. |
the hippocampus plays an important role in maintaining normal cognitive function and is closely associated with the neuropathogenesis of dementia. |
2022-07-27 |
2023-08-14 |
mouse |
| Jian Zhao, Wenqiang Li, Yue Wang, Yuanhe Jiang, Chunyan Ding, Huaibin Li, Jian Ding, Lin Wan. The effect of electroacupuncture on the expression of Sirt1 and STAT3 in hippocampus and amygdala of vascular dementia rats. Neuroreport. 2022-07-26. PMID:35882013. |
the effect of electroacupuncture on the expression of sirt1 and stat3 in hippocampus and amygdala of vascular dementia rats. |
2022-07-26 |
2023-08-14 |
rat |
| Alexander J Billig, Meher Lad, William Sedley, Timothy D Griffith. The hearing hippocampus. Progress in neurobiology. 2022-07-23. PMID:35870677. |
more deeply understanding these interactions may unlock applications including entraining hippocampal rhythms to support cognition, and intervening in links between hearing loss and dementia. |
2022-07-23 |
2023-08-14 |
Not clear |
| Balaji Kannappan, Tamil Iniyan Gunasekaran, Jan Te Nijenhuis, Muthu Gopal, Deepika Velusami, Gugan Kothandan, Kun Ho Le. Polygenic score for Alzheimer's disease identifies differential atrophy in hippocampal subfield volumes. PloS one. vol 17. issue 7. 2022-07-13. PMID:35830443. |
in this study, we evaluated the polygenic risk of alzheimer's disease (ad pgrs) for hippocampal subfield atrophy in 1,086 individuals (319 cognitively normal (cn), 591 mild cognitively impaired (mci), and 176 alzheimer's disease dementia (add)). |
2022-07-13 |
2023-08-14 |
Not clear |