| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron Y Lai, Paolo Bazzigaluppi, Christopher D Morrone, Mary E Hill, Bojana Stefanovic, JoAnne McLauri. Compromised Cortical-Hippocampal Network Function From Transient Hypertension: Linking Mid-Life Hypertension to Late Life Dementia Risk. Frontiers in neuroscience. vol 16. 2022-07-11. PMID:35812238. |
our results demonstrate that connectivity between prefrontal cortex and hippocampus is a vulnerable network affected by transient hypertension which is not rescued over time; thus demonstrating for the first time a mechanistic link between the long-term effects of transient hypertension and dementia risk. |
2022-07-11 |
2023-08-14 |
rat |
| Shoichiro Maeda, Jun Yamada, Kyoko M Iinuma, Satomi Nadanaka, Hiroshi Kitagawa, Shozo Jinn. Chondroitin sulfate proteoglycan is a potential target of memantine to improve cognitive function via the promotion of adult neurogenesis. British journal of pharmacology. 2022-07-07. PMID:35797426. |
the reduction of hippocampal neurogenesis is involved in aging-related cognitive decline and dementia. |
2022-07-07 |
2023-08-14 |
Not clear |
| Ryszard Pluta, Sławomir Januszewski, Stanisław J Czuczwa. Molecular Hydrogen Neuroprotection in Post-Ischemic Neurodegeneration in the Form of Alzheimer's Disease Proteinopathy: Underlying Mechanisms and Potential for Clinical Implementation-Fantasy or Reality? International journal of molecular sciences. vol 23. issue 12. 2022-06-24. PMID:35743035. |
the death of pyramidal neurons in especially the ca1 area of the hippocampus, increased permeability of the blood-brain barrier, neuroinflammation, amyloid accumulation, tau protein dysfunction, brain atrophy, cognitive deficits and dementia are considered an integral part of the phenomena occurring during brain neurodegeneration after ischemia. |
2022-06-24 |
2023-08-14 |
Not clear |
| Bin Han, Hui Zhao, Xingji Gong, Jinping Sun, Song Chi, Tao Liu, Anmu Xi. Upregulation of PGC-1 Neural plasticity. vol 2022. 2022-06-20. PMID:35719138. |
upregulation of pgc-1 hippocampal neuronal damage likely underlies cognitive impairment in vascular dementia (vad). |
2022-06-20 |
2023-08-14 |
Not clear |
| Nicole J Gervais, Laura Gravelsins, Alana Brown, Rebekah Reuben, Laurice Karkaby, Elizabeth Baker-Sullivan, Leanne Mendoza, Claire Lauzon, Anne Almey, William D Foulkes, Marcus Q Bernardini, Michelle Jacobson, Lea Velsher, M Natasha Rajah, Rosanna K Olsen, Cheryl Grady, Gillian Einstei. Scene memory and hippocampal volume in middle-aged women with early hormone loss. Neurobiology of aging. vol 117. 2022-06-13. PMID:35696793. |
these findings show that hippocampal subfield volume may be useful for identifying early midlife changes in women at elevated risk for dementia. |
2022-06-13 |
2023-08-14 |
Not clear |
| Abbie C Johnson, Sarah M Tremble, Marilyn J Cipoll. Experimental Preeclampsia Causes Long-Lasting Hippocampal Vascular Dysfunction and Memory Impairment. Frontiers in physiology. vol 13. 2022-05-26. PMID:35615682. |
pe increases the risk of vascular dementia three-fold, however, long-lasting effects of pe on the vasculature of vulnerable brain regions involved in memory and cognition, such as the hippocampus, remain unknown. |
2022-05-26 |
2023-08-13 |
rat |
| Osama Hamadelseed, Ibrahim H Elkhidir, Thomas Skutell. Psychosocial Risk Factors for Alzheimer's Disease in Patients with Down Syndrome and Their Association with Brain Changes: A Narrative Review. Neurology and therapy. 2022-05-21. PMID:35596914. |
people with down syndrome living with dementia showed reduced volumes of brain areas affected by alzheimer's disease as the hippocampus and corpus callosum in association with cognitive decline. |
2022-05-21 |
2023-08-13 |
Not clear |
| Anna Mietelska-Porowska, Justyna Domańska, Andrew Want, Angelika Więckowska-Gacek, Dominik Chutorański, Maciej Koperski, Urszula Wojd. Induction of Brain Insulin Resistance and Alzheimer's Molecular Changes by Western Diet. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563135. |
ad is the main cause of progressive dementia characterized by the deposition of amyloid-β (aβ) plaques and neurofibrillary tangles consisting of the hyperphosphorylated tau (p-tau) protein in the brain, starting from the entorhinal cortex and the hippocampus. |
2022-05-14 |
2023-08-13 |
mouse |
| Patrick Miller-Rhodes, Herman Li, Ravikanth Velagapudi, Wesley Chiang, Niccolò Terrando, Harris A Gelbar. URMC-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36. issue 6. 2022-05-10. PMID:35535564. |
urmc-099 prophylaxis prevents hippocampal vascular vulnerability and synaptic damage in an orthopedic model of delirium superimposed on dementia. |
2022-05-10 |
2023-08-13 |
Not clear |
| Borislav Radić, Antonela Blažeković, Din Duraković, Anka Jurišić-Kvesić, Ervina Bilić, Fran Borovečk. Could Mental and Physical Exercise Alleviate Alzheimer's Disease? Psychiatria Danubina. vol 33. issue Suppl 4. 2022-05-03. PMID:35503939. |
complex mental activity during life is associated with a reduction in the hippocampal atrophy rate, which is a sensitive early-stage biomarker of dementia while regular physical exercise can slow down the progressive reduction of the cortical brain volume which occurs during aging. |
2022-05-03 |
2023-08-13 |
Not clear |
| Rong-Rong Qiu, Hong Zhang, Chang Deng, Dan-Feng Chen, Ya-Yu Xu, Dan Xiong, Ying-Jie Zou, Jie Ta. [Effects of electroacupuncture on ROS-NLRP3 inflammatory pathway and autophagy related proteins in hippocampus of vascular dementia rats]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 4. 2022-04-29. PMID:35486008. |
[effects of electroacupuncture on ros-nlrp3 inflammatory pathway and autophagy related proteins in hippocampus of vascular dementia rats]. |
2022-04-29 |
2023-08-13 |
rat |
| Rong-Rong Qiu, Hong Zhang, Chang Deng, Dan-Feng Chen, Ya-Yu Xu, Dan Xiong, Ying-Jie Zou, Jie Ta. [Effects of electroacupuncture on ROS-NLRP3 inflammatory pathway and autophagy related proteins in hippocampus of vascular dementia rats]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 4. 2022-04-29. PMID:35486008. |
to observe the effect of electroacupuncture (ea) on learning-memory ability, ultrastructural changes of hippocampal ca1 neurons, reactive oxygen species (ros) level, nod-like receptor protein 3 (nlrp3) and auto-phagy-related proteins expression in the hippocampus of vascular dementia (vd) rats, so as to reveal its partial mechanisms in treating vd. |
2022-04-29 |
2023-08-13 |
rat |
| Panteleimon Giannakopoulos, Marie-Louise Montandon, François R Herrmann, Dennis Hedderich, Christian Gaser, Elias Kellner, Cristelle Rodriguez, Sven Halle. Alzheimer resemblance atrophy index, BrainAGE, and normal pressure hydrocephalus score in the prediction of subtle cognitive decline: added value compared to existing MR imaging markers. European radiology. 2022-04-29. PMID:35486172. |
established visual brain mri markers for dementia include hippocampal atrophy (mesio-temporal atrophy mta), white matter lesions (fazekas score), and number of cerebral microbleeds (cmbs). |
2022-04-29 |
2023-08-13 |
Not clear |
| Yu Ren, Qing Wang, Zexian Yang, Linyin Feng, Yu Zhan. MCC950 ameliorates the dementia symptom at the early age of line M83 mouse and reduces hippocampal α-synuclein accumulation. Biochemical and biophysical research communications. vol 611. 2022-04-26. PMID:35472607. |
mcc950 ameliorates the dementia symptom at the early age of line m83 mouse and reduces hippocampal α-synuclein accumulation. |
2022-04-26 |
2023-08-13 |
mouse |
| Shunsuke Takagi, Katsumi Yamashiro, Genichi Sugihara, Masato Matsuura, Hidehiko Takahash. Hippocampal calcification and its effects on cognitive function and symptoms in dementia. Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society. 2022-04-21. PMID:35445506. |
hippocampal calcification and its effects on cognitive function and symptoms in dementia. |
2022-04-21 |
2023-08-13 |
Not clear |
| Ian M McDonough, Christopher Mayhugh, Mary Katherine Moore, Mikenzi B Brasfield, Sarah K Letang, Christopher R Madan, Rebecca S Alle. Young Adults with a Parent with Dementia Show Early Abnormalities in Brain Activity and Brain Volume in the Hippocampus: A Matched Case-Control Study. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35448026. |
young adults with a parent with dementia show early abnormalities in brain activity and brain volume in the hippocampus: a matched case-control study. |
2022-04-21 |
2023-08-13 |
Not clear |
| Ian M McDonough, Christopher Mayhugh, Mary Katherine Moore, Mikenzi B Brasfield, Sarah K Letang, Christopher R Madan, Rebecca S Alle. Young Adults with a Parent with Dementia Show Early Abnormalities in Brain Activity and Brain Volume in the Hippocampus: A Matched Case-Control Study. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35448026. |
young adults with a parent with dementia showed greater resting mean activity and smaller volumes in the left hippocampus compared to young adults without a parent with dementia. |
2022-04-21 |
2023-08-13 |
Not clear |
| Ian M McDonough, Christopher Mayhugh, Mary Katherine Moore, Mikenzi B Brasfield, Sarah K Letang, Christopher R Madan, Rebecca S Alle. Young Adults with a Parent with Dementia Show Early Abnormalities in Brain Activity and Brain Volume in the Hippocampus: A Matched Case-Control Study. Brain sciences. vol 12. issue 4. 2022-04-21. PMID:35448026. |
this early hippocampal dysfunction may be due to aberrant neural firing, which may increase the risk for a diagnosis of dementia in old age. |
2022-04-21 |
2023-08-13 |
Not clear |
| Abbie C Johnson, Friederike Uhlig, Zachary Einwag, Noelle Cataldo, Benedek Erdo. The neuroendocrine stress response impairs hippocampal vascular function and memory in male and female rats. Neurobiology of disease. 2022-04-06. PMID:35385769. |
chronic psychological stress affects brain regions involved in memory such as the hippocampus and accelerates age-related cognitive decline, including in alzheimer's disease and vascular dementia. |
2022-04-06 |
2023-08-13 |
rat |
| Ruhul Amin Hazarika, Arnab Kumar Maji, Raplang Syiem, Samarendra Nath Sur, Debdatta Kanda. Hippocampus Segmentation Using U-Net Convolutional Network from Brain Magnetic Resonance Imaging (MRI). Journal of digital imaging. 2022-03-19. PMID:35304675. |
by segmenting and analyzing the size/shape of hippocampus, it may be possible to classify the early dementia stages. |
2022-03-19 |
2023-08-13 |
human |