| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lei Gao, Fushun Liu, Ruilian Li. The Mechanism of Aerobic Exercise Regulating the PI3K/Akt-mTOR Signaling Pathway Intervenes in Hippocampal Neuronal Apoptosis in Vascular Dementia Rats. International journal of environmental research and public health. vol 20. issue 3. 2023-02-11. PMID:36767264. |
the mechanism of aerobic exercise regulating the pi3k/akt-mtor signaling pathway intervenes in hippocampal neuronal apoptosis in vascular dementia rats. |
2023-02-11 |
2023-08-14 |
rat |
| Lei Gao, Fushun Liu, Ruilian Li. The Mechanism of Aerobic Exercise Regulating the PI3K/Akt-mTOR Signaling Pathway Intervenes in Hippocampal Neuronal Apoptosis in Vascular Dementia Rats. International journal of environmental research and public health. vol 20. issue 3. 2023-02-11. PMID:36767264. |
the purpose of this paper is to explore the mechanism of aerobic exercise regulating autophagy through the pi3k/akt-mtor signaling pathway and its participation in apoptosis, to protect the hippocampal nerves from damage in vascular dementia rats. |
2023-02-11 |
2023-08-14 |
rat |
| Andreas Christoper, Herry Herman, Rizky Abdulah, Felix Zulhendri, Ardo Sanjaya, Ronny Lesman. Physiological Roles of Hippo Signaling Pathway and Autophagy in Dementia. Current aging science. 2023-02-06. PMID:36744694. |
dementia is a neurocognitive disorder associated with the aging brain and mainly affects the hippocampus and cerebral cortex. |
2023-02-06 |
2023-08-14 |
Not clear |
| Jun Yup Lee, Dylan Harney, John Kwok, Mark Larance, Anthony Simon Do. The major TMEM106B dementia risk allele affects TMEM106B protein levels and myelin lipid homeostasis in the ageing human hippocampus. Research square. 2023-01-30. PMID:36711721. |
the major tmem106b dementia risk allele affects tmem106b protein levels and myelin lipid homeostasis in the ageing human hippocampus. |
2023-01-30 |
2023-08-14 |
human |
| Jun Yup Lee, Dylan Harney, John Kwok, Mark Larance, Anthony Simon Do. The major TMEM106B dementia risk allele affects TMEM106B protein levels and myelin lipid homeostasis in the ageing human hippocampus. Research square. 2023-01-30. PMID:36711721. |
this study aimed to determine how ageing and major genetic risk factors for dementia affect the hippocampal proteome and lipidome of neurologically-normal humans over the age of 65. |
2023-01-30 |
2023-08-14 |
human |
| Praveen Bathini, Isabel Dupanloup, Elena Zenaro, Eleonora Terrabuio, Amrei Fischer, Edona Ballabani, Marie-Agnes Doucey, Lavinia Alber. Systemic Inflammation Causes Microglial Dysfunction With a Vascular AD phenotype. Brain, behavior, & immunity - health. vol 28. 2023-01-27. PMID:36704658. |
our study aimed to assess the temporal evolution of the pathological impact of systemic inflammation evoked by prenatal and early postnatal peripheral exposure of viral mimetic polyinosinic:polycytidylic acid (polyi:c) and compare the hippocampal transcriptomic changes with the profiles of human post-mortem ad and vascular dementia brain specimens. |
2023-01-27 |
2023-08-14 |
human |
| Juan Rivas, Santiago Gutierrez-Gomez, Juliana Villanueva-Congote, Jose Libreros, Joan Albert Camprodon, María Trujill. Subcortical Structures in Demented Schizophrenia Patients: A Comparative Study. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672741. |
structural differences were found in the hippocampus, amygdala, and thalamus; more evident in the amygdala and thalamus, which were mainly related to dementia. |
2023-01-21 |
2023-08-14 |
Not clear |
| Juan Rivas, Santiago Gutierrez-Gomez, Juliana Villanueva-Congote, Jose Libreros, Joan Albert Camprodon, María Trujill. Subcortical Structures in Demented Schizophrenia Patients: A Comparative Study. Biomedicines. vol 11. issue 1. 2023-01-21. PMID:36672741. |
moreover, volume lost in the hippocampus, amygdala, and thalamus may be related to the possibility to develop dementia in schizophrenic patients. |
2023-01-21 |
2023-08-14 |
Not clear |
| Christine Yuan, Jayme M Palka, Anand Rohatgi, Parag Joshi, Jarrett Berry, Amit Khera, E Sherwood Brow. The Relationship Between Coronary Artery Calcification and Carotid Intima Media Thickness, and Hippocampal volume: An Analysis from the Dallas Heart Study. Journal of the Academy of Consultation-Liaison Psychiatry. 2023-01-21. PMID:36681150. |
smaller hippocampal volume (hv) is a risk factor for the development of dementia. |
2023-01-21 |
2023-08-14 |
Not clear |
| Kun Zhao, Yanhui Ding, Ying Han, Yong Fan, Aaron F Alexander-Bloch, Tong Han, Dan Jin, Bing Liu, Jie Lu, Chengyuan Song, Pan Wang, Dawei Wang, Qing Wang, Kaibin Xu, Hongwei Yang, Hongxiang Yao, Yuanjie Zheng, Chunshui Yu, Bo Zhou, Xinqing Zhang, Yuying Zhou, Tianzi Jiang, Xi Zhang, Yong Li. Independent and reproducible hippocampal radiomic biomarkers for multisite Alzheimer's disease: diagnosis, longitudinal progress and biological basis. Science bulletin. vol 65. issue 13. 2023-01-20. PMID:36659162. |
however, whether hippocampal radiomic features are robust as predictors of progression from mild cognitive impairment (mci) to ad dementia and whether these features provide any neurobiological foundation remains unclear. |
2023-01-20 |
2023-08-14 |
human |
| Jessica Pommy, L Conant, A M Butts, A Nencka, Y Wang, M Franczak, L Glass-Umflee. A graph theoretic approach to neurodegeneration: five data-driven neuropsychological subtypes in mild cognitive impairment. Neuropsychology, development, and cognition. Section B, Aging, neuropsychology and cognition. 2023-01-17. PMID:36648118. |
community membership was significantly associated with 1) cortical volume in the hippocampus, entorhinal cortex, and fusiform cortex; 2) fdg pet hypometabolism in the posterior cingulate, angular gyrus, and inferior/middle temporal gyrus; and 3) conversion to dementia at follow up. |
2023-01-17 |
2023-08-14 |
Not clear |
| Shaimaa M Azzam, Amina A S Abdel Rahman, Omar Abdel-Hamed Ahmed Farid, Wael Mohamed Abu El-Wafa, Gad Elsayed Mohamed Sale. Lipopolysaccharide induced neuroprotective effects of bacterial protease against Alzheimer's disease in male Wistar albino rats. International journal of biological macromolecules. 2023-01-15. PMID:36642360. |
alzheimer's disease (ad) is a highly severe neurodegenerative condition that affects the hippocampus and is characterized by memory loss and dementia. |
2023-01-15 |
2023-08-14 |
rat |
| Michael R Fiorini, Allison A Dilliott, Sali M K Farha. Sex-stratified RNA-seq analysis reveals traumatic brain injury-induced transcriptional changes in the female hippocampus conducive to dementia. Frontiers in neurology. vol 13. 2023-01-09. PMID:36619915. |
sex-stratified rna-seq analysis reveals traumatic brain injury-induced transcriptional changes in the female hippocampus conducive to dementia. |
2023-01-09 |
2023-08-14 |
Not clear |
| Keita Watanabe, Naomichi Okamoto, Issei Ueda, Hirofumi Tesen, Rintaro Fujii, Atsuko Ikenouchi, Reiji Yoshimura, Shingo Kaked. Disturbed hippocampal intra-network in first-episode of drug-naïve major depressive disorder. Brain communications. vol 5. issue 1. 2023-01-05. PMID:36601619. |
complex networks inside the hippocampus could provide new insights into hippocampal abnormalities in various psychiatric disorders and dementia. |
2023-01-05 |
2023-08-14 |
human |
| Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications. vol 11. issue 1. 2023-01-03. PMID:36597124. |
the dentate gyrus (dg), a key hippocampal subregion in memory processing, generally resists phosphorylated tau accumulation in the amnestic dementia of the alzheimer's type due to alzheimer's disease (dat-ad), but less is known about the susceptibility of the dg to other tauopathies. |
2023-01-03 |
2023-08-14 |
human |
| Allegra Kawles, Grace Minogue, Antonia Zouridakis, Rachel Keszycki, Nathan Gill, Caren Nassif, Christina Coventry, Hui Zhang, Emily Rogalski, Margaret E Flanagan, Rudolph Castellani, Eileen H Bigio, M Marsel Mesulam, Changiz Geula, Tamar Gefe. Differential vulnerability of the dentate gyrus to tauopathies in dementias. Acta neuropathologica communications. vol 11. issue 1. 2023-01-03. PMID:36597124. |
we conclude that the dg is differentially vulnerable to pathologic tau accumulation, raising intriguing questions about the structural integrity and functional significance of hippocampal circuits in neurodegenerative dementias. |
2023-01-03 |
2023-08-14 |
human |
| Jie Guo, Ying-Qian Zhao, Hua Li, Gai-Yue Zhang, Yuan-Rong Lu, Pan-Pan Guo, Qiang Wan. [Effect of electroacupuncture on hippocampal synaptic plasticity and complement dependent memory impairment in Parkinson's disease dementia mice]. Zhen ci yan jiu = Acupuncture research. vol 47. issue 12. 2022-12-26. PMID:36571217. |
[effect of electroacupuncture on hippocampal synaptic plasticity and complement dependent memory impairment in parkinson's disease dementia mice]. |
2022-12-26 |
2023-08-14 |
mouse |
| George P Paraskevas, Vasilios C Constantinides, Fotini Boufidou, Ioanna Tsantzali, Efstratios-Stylianos Pyrgelis, Georgios Liakakis, Elisabeth Kapak. Recognizing Atypical Presentations of Alzheimer's Disease: The Importance of CSF Biomarkers in Clinical Practice. Diagnostics (Basel, Switzerland). vol 12. issue 12. 2022-12-23. PMID:36553018. |
among 98 patients with the csf ad profile, 46% of patients had the typical presentation of "hippocampal" amnestic dementia. |
2022-12-23 |
2023-08-14 |
Not clear |
| Victor Coelho, Luisa Bandeira Binder, Naiani Ferreira Marques, Leandra Celso Constantino, Gianni Mancini, Carla Inês Tasc. Guanosine Prevents Spatial Memory Impairment and Hippocampal Damage Following Amyloid-β Metabolites. vol 12. issue 12. 2022-12-23. PMID:36557245. |
guanosine prevents spatial memory impairment and hippocampal damage following amyloid-β alzheimer's disease (ad) is a progressive neurodegenerative illness responsible for cognitive impairment and dementia. |
2022-12-23 |
2023-08-14 |
Not clear |
| Chloé Savignac, Sylvia Villeneuve, AmanPreet Badhwar, Karin Saltoun, Kimia Shafighi, Chris Zajner, Vaibhav Sharma, Sarah A Gagliano Taliun, Sali Farhan, Judes Poirier, Danilo Bzdo. APOE alleles are associated with sex-specific structural differences in brain regions affected in Alzheimer's disease and related dementia. PLoS biology. vol 20. issue 12. 2022-12-13. PMID:36512526. |
here, we examined codependent structural variations between the mtl's most vulnerable structure, the hippocampus (hc), and the dn at subregion resolution in individuals with alzheimer's disease and related dementia (adrd). |
2022-12-13 |
2023-08-14 |
human |