| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with alzheimer's disease and dementia with lewy bodies. |
2022-03-17 |
2023-08-13 |
Not clear |
| Sonja Fixemer, Corrado Ameli, Gaël Hammer, Luis Salamanca, Oihane Uriarte Huarte, Chantal Schwartz, Jean-Jacques Gérardy, Naguib Mechawar, Alexander Skupin, Michel Mittelbronn, David S Bouvie. Microglia phenotypes are associated with subregional patterns of concomitant tau, amyloid-β and α-synuclein pathologies in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies. Acta neuropathologica communications. vol 10. issue 1. 2022-03-17. PMID:35296366. |
the cellular alterations of the hippocampus lead to memory decline, a shared symptom between alzheimer's disease (ad) and dementia with lewy bodies (dlb) patients. |
2022-03-17 |
2023-08-13 |
Not clear |
| Martina Sassi, Alwena H Morgan, Jeffrey S Davie. Ghrelin Acylation-A Post-Translational Tuning Mechanism Regulating Adult Hippocampal Neurogenesis. Cells. vol 11. issue 5. 2022-03-10. PMID:35269387. |
in this short review, we discuss the evidence for ghrelin's role in regulating adult hippocampal neurogenesis and the enzymes involved in ghrelin acylation and de-acylation as targets to treat mood-related disorders and dementia. |
2022-03-10 |
2023-08-13 |
mouse |
| Madeline H Meier, Avshalom Caspi, Annchen R Knodt, Wayne Hall, Antony Ambler, HonaLee Harrington, Sean Hogan, Renate M Houts, Richie Poulton, Sandhya Ramrakha, Ahmad R Hariri, Terrie E Moffit. Long-Term Cannabis Use and Cognitive Reserves and Hippocampal Volume in Midlife. The American journal of psychiatry. 2022-03-08. PMID:35255711. |
this study tested the hypotheses that long-term cannabis use is associated with cognitive deficits and smaller hippocampal volume in midlife, which is important because midlife cognitive deficits and smaller hippocampal volume are risk factors for dementia. |
2022-03-08 |
2023-08-13 |
Not clear |
| Stephanie Mangesius, Lukas Haider, Lukas Lenhart, Ruth Steiger, Ferran Prados Carrasco, Christoph Scherfler, Elke R Gizewsk. Qualitative and Quantitative Comparison of Hippocampal Volumetric Software Applications: Do All Roads Lead to Rome? Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203641. |
ten cases with and ten gender- and age-adjusted healthy controls without hippocampal atrophy (median age: 70; 25-75% range: 64-77 years and 74; 66-78 years) were retrospectively selected from a previously published cohort of alzheimer's dementia patients and normal ageing controls. |
2022-02-25 |
2023-08-13 |
Not clear |
| Eun Chae Lee, Dong-Yong Hong, Dong-Hun Lee, Sang-Won Park, Ji Young Lee, Ji Hun Jeong, Eun-Young Kim, Hyung-Min Chung, Ki-Sung Hong, Se-Pill Park, Man Ryul Lee, Jae Sang O. Inflammation and Rho-Associated Protein Kinase-Induced Brain Changes in Vascular Dementia. Biomedicines. vol 10. issue 2. 2022-02-25. PMID:35203655. |
however, expression of claudin-5, which maintains the blood-brain barrier, and map2 as a nerve cell-specific factor, was decreased in the hippocampal region of the vascular dementia model. |
2022-02-25 |
2023-08-13 |
mouse |
| Kai Sin Chin, Sanuji Gajamange, Patricia M Desmond, Victor L Villemagne, Christopher C Rowe, Leonid Churilov, Nawaf Yassi, Rosie Watso. Association between amyloid-beta deposition and cortical thickness in dementia with Lewy bodies. The Australian and New Zealand journal of psychiatry. 2022-02-24. PMID:35196886. |
this study aimed to investigate the clinical and imaging correlates of amyloid-beta deposition in dementia with lewy bodies, particularly its relationship with cortical thickness in alzheimer's disease-prone regions and hippocampal volume. |
2022-02-24 |
2023-08-13 |
Not clear |
| Mohammad Davood Sharifi, Narges Karimi, Mohammad Karami, Afshin Borhani Haghighi, Mohammad Shabani, Mahnaz Baya. The Minocycline Ameliorated the Synaptic Plasticity Impairment in Vascular Dementia. Iranian journal of pharmaceutical research : IJPR. vol 20. issue 4. 2022-02-23. PMID:35194458. |
chronic cerebral hypoperfusion (cch) leads to vascular dementia with progressive hippocampal damage and cognitive impairments. |
2022-02-23 |
2023-08-13 |
Not clear |
| Hristian Staykov, Maria Lazarova, Yozljam Hassanova, Miroslava Stefanova, Lyubka Tancheva, Rumen Nikolo. Neuromodulatory Mechanisms of a Memory Loss-Preventive Effect of Alpha-Lipoic Acid in an Experimental Rat Model of Dementia. Journal of molecular neuroscience : MN. 2022-02-17. PMID:35174445. |
according to the data available, this is the first time that ala-induced changes in ache and monoamine levels in the prefrontal cortex and hippocampus (brain structures related to learning and memory) have been demonstrated in a sco-induced rat model of ad type dementia. |
2022-02-17 |
2023-08-13 |
rat |
| Emily Rosenich, Lisa Bransby, Nawaf Yassi, Jurgen Fripp, Simon M Laws, Ralph N Martins, Christopher Fowler, Stephanie R Rainey-Smith, Christopher C Rowe, Colin L Masters, Paul Maruff, Yen Ying Li. Differential Effects of APOE and Modifiable Risk Factors on Hippocampal Volume Loss and Memory Decline in AB- and AB+ Older Adults. Neurology. 2022-02-16. PMID:35169009. |
this prospective study sought to determine the association of modifiable/non-modifiable components included in the cardiovascular risk factors, aging, and incidence of dementia (caide) risk score with hippocampal volume (hv) loss and episodic memory (em) decline in cognitively normal (cn) older adults classified as brain β-amyloid negative (aβ-) or aβ+. |
2022-02-16 |
2023-08-13 |
Not clear |
| Sasha A Philbert, Jingshu Xu, Melissa Scholefield, Stephanie J Church, Richard D Unwin, Garth J S Coope. Contrasting Sodium and Potassium Perturbations in the Hippocampus Indicate Potential Na Frontiers in aging neuroscience. vol 14. 2022-02-14. PMID:35153731. |
contrasting sodium and potassium perturbations in the hippocampus indicate potential na vascular dementia (vad) is thought to be the second most common cause of age-related dementia amongst the elderly. |
2022-02-14 |
2023-08-13 |
Not clear |
| N D Koblinsky, N D Anderson, F Ajwani, M D Parrott, D Dawson, S Marzolini, P Oh, B MacIntosh, L Middleton, G Ferland, C E Greenwoo. Feasibility and preliminary efficacy of the LEAD trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia. Pilot and feasibility studies. vol 8. issue 1. 2022-02-10. PMID:35139918. |
feasibility and preliminary efficacy of the lead trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia. |
2022-02-10 |
2023-08-13 |
Not clear |
| N D Koblinsky, N D Anderson, F Ajwani, M D Parrott, D Dawson, S Marzolini, P Oh, B MacIntosh, L Middleton, G Ferland, C E Greenwoo. Feasibility and preliminary efficacy of the LEAD trial: a cluster randomized controlled lifestyle intervention to improve hippocampal volume in older adults at-risk for dementia. Pilot and feasibility studies. vol 8. issue 1. 2022-02-10. PMID:35139918. |
our objective was to evaluate the feasibility and preliminary efficacy of a 6-month intervention combining exercise with a novel dietary counseling approach to improve hippocampal volume among older adults at-risk for dementia. |
2022-02-10 |
2023-08-13 |
Not clear |
| Risna K Radhakrishnan, Mahesh Kandasam. SARS-CoV-2-Mediated Neuropathogenesis, Deterioration of Hippocampal Neurogenesis and Dementia. American journal of Alzheimer's disease and other dementias. vol 37. 2022-02-08. PMID:35133907. |
sars-cov-2-mediated neuropathogenesis, deterioration of hippocampal neurogenesis and dementia. |
2022-02-08 |
2023-08-13 |
human |
| Risna K Radhakrishnan, Mahesh Kandasam. SARS-CoV-2-Mediated Neuropathogenesis, Deterioration of Hippocampal Neurogenesis and Dementia. American journal of Alzheimer's disease and other dementias. vol 37. 2022-02-08. PMID:35133907. |
considering the facts, this article describes the prominent neuropathogenic characteristics and neurocognitive impairments in covid-19 and emphasizes a viewpoint that neuroinflammation-mediated deterioration of hippocampal neurogenesis could contribute to the onset and progression of dementia in covid-19. |
2022-02-08 |
2023-08-13 |
human |
| Miguel Germán Borda, Nicolás Castellanos-Perilla, Diego Alejandro Tovar-Rios, Daniel Ferreira, Gustavo Duque, Dag Aarslan. Tongue muscle mass is associated with total grey matter and hippocampal volumes in Dementia with Lewy Bodies. Archives of gerontology and geriatrics. vol 100. 2022-02-08. PMID:35134612. |
tongue muscle mass is associated with total grey matter and hippocampal volumes in dementia with lewy bodies. |
2022-02-08 |
2023-08-13 |
Not clear |
| Davis C Woodworth, Mari Perez-Rosendahl, Hannah L Nguyen, Kiana Alexis Scambray, Michael J Phelan, Maria M Corrada, Claudia H Kawas, S Ahmad Sajjad. Dementia is strongly associated with severity of hippocampal atrophy at autopsy even after accounting for degenerative neuropathologies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109158. |
dementia is strongly associated with severity of hippocampal atrophy at autopsy even after accounting for degenerative neuropathologies. |
2022-02-03 |
2023-08-13 |
Not clear |
| Davis C Woodworth, Mari Perez-Rosendahl, Hannah L Nguyen, Kiana Alexis Scambray, Michael J Phelan, Maria M Corrada, Claudia H Kawas, S Ahmad Sajjad. Dementia is strongly associated with severity of hippocampal atrophy at autopsy even after accounting for degenerative neuropathologies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109158. |
recent work from our research group has shown that dementia is strongly associated with hippocampal atrophy from in-vivo mri even after accounting for degenerative neuropathologies. |
2022-02-03 |
2023-08-13 |
Not clear |
| Davis C Woodworth, Mari Perez-Rosendahl, Hannah L Nguyen, Kiana Alexis Scambray, Michael J Phelan, Maria M Corrada, Claudia H Kawas, S Ahmad Sajjad. Dementia is strongly associated with severity of hippocampal atrophy at autopsy even after accounting for degenerative neuropathologies. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109158. |
we sought to confirm this finding using ratings of hippocampal atrophy at autopsy and examining their relationship with dementia while also accounting for relevant degenerative neuropathologies. |
2022-02-03 |
2023-08-13 |
Not clear |
| Gabriel Casagrande Zabot, Eduarda Behenck Medeiros, Ariandne Oliveira Marques, Bárbara Machado Naspolini Macarini, Adrielly Vargas, Ana Carolina Nunes Colombo, João Behenck, Gustavo De Bem Silveira, Gabriela Serafim Keller, Lisienny Campoli Tono Rempel, Daniel Proença Feijó, Ewa Kucharska, Paulo Cesar Lock Silveira, Gislaine Zilli Réus, Josiane Budn. The involvement of inflammation in the effect of the administration of donepezil, galantamine, memantine and/or fluoxetine in an animal model of depression and dementia. Alzheimer's & dementia : the journal of the Alzheimer's Association. vol 17 Suppl 3. 2022-02-03. PMID:35109296. |
therefore, the present study evaluated the levels of cytokines such as tumor necrosis factor alpha (tnf-α), interleukin (il) -1β, il-6 and il-10 in the frontal cortex and hippocampus of wistar rats subjected to chronic mild stress protocol (cms) for induction of an animal model of depression and administration of intra-hippocampal β-amyloid (βa) oligomers for induction of the dementia model. |
2022-02-03 |
2023-08-13 |
rat |