| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anna Athanassi, Marine Breton, Laura Chalençon, Jérome Brunelin, Anne Didier, Kevin Bath, Nathalie Mandairo. Chronic unpredictable mild stress alters odor hedonics and adult olfactory neurogenesis in mice. Frontiers in neuroscience. vol 17. 2023-08-21. PMID:37600017. |
in hippocampus, decreased neurogenesis has been linked to development or maintenance of depression symptoms. |
2023-08-21 |
2023-09-07 |
mouse |
| Jian-Bin Ge, Bo Jiang, Tian-Shun Shi, Wei-Yu Li, Wei-Jia Chen, Bao-Lun Zhu, Zheng-Hong Qi. Cucurbitacin B exerts significant antidepressant-like effects in a chronic unpredictable mild stress model of depression: Involvement of the hippocampal BDNF-TrkB system. The international journal of neuropsychopharmacology. 2023-08-21. PMID:37603290. |
cucurbitacin b exerts significant antidepressant-like effects in a chronic unpredictable mild stress model of depression: involvement of the hippocampal bdnf-trkb system. |
2023-08-21 |
2023-09-07 |
mouse |
| Marco Paolini, Yasmin Harrington, Federica Colombo, Valentina Bettonagli, Sara Poletti, Matteo Carminati, Cristina Colombo, Francesco Benedetti, Raffaella Zanard. Hippocampal and parahippocampal volume and function predict antidepressant response in patients with major depression: A multimodal neuroimaging study. Journal of psychopharmacology (Oxford, England). 2023-08-17. PMID:37589290. |
hippocampal and parahippocampal volume and function predict antidepressant response in patients with major depression: a multimodal neuroimaging study. |
2023-08-17 |
2023-09-07 |
Not clear |
| Daisuke Ibi, Genki Nakasai, Masahito Sawahata, Rika Takaba, Maho Kinoshita, Kiyofumi Yamada, Masayuki Hiramats. Emotional behaviors as well as the hippocampal reelin expression in C57BL/6N male mice chronically treated with corticosterone. Pharmacology, biochemistry, and behavior. 2023-08-10. PMID:37562494. |
these results suggest that c57bl/6n male mice chronically treated with cort are a suitable animal depression model, in which depressive behaviors may occur independently of the alternation of hippocampal reelin expression. |
2023-08-10 |
2023-08-16 |
mouse |
| Chang Hyeon Kong, Keontae Park, Do Yeon Kim, Jae Youn Kim, Woo Chang Kang, Mijin Jeon, Ji Won Min, Won Hyung Lee, Seo Yun Jung, Jong Hoon Ry. Effects of oleanolic acid and ursolic acid on depression-like behaviors induced by maternal separation in mice. European journal of pharmacology. 2023-08-04. PMID:37541369. |
depression is a mental illness caused by neuroinflammation or changes in neuroplasticity in certain brain regions, such as the prefrontal cortex and hippocampus. |
2023-08-04 |
2023-08-14 |
mouse |
| Ning Sun, Wen-Qiang Cui, Xiao-Man Min, Guang-Ming Zhang, Jia-Zheng Liu, Hong-Yun W. A new perspective on hippocampal synaptic plasticity and post-stroke depression. The European journal of neuroscience. 2023-07-31. PMID:37518943. |
a new perspective on hippocampal synaptic plasticity and post-stroke depression. |
2023-07-31 |
2023-08-14 |
Not clear |
| Ning Sun, Wen-Qiang Cui, Xiao-Man Min, Guang-Ming Zhang, Jia-Zheng Liu, Hong-Yun W. A new perspective on hippocampal synaptic plasticity and post-stroke depression. The European journal of neuroscience. 2023-07-31. PMID:37518943. |
hippocampal synaptic plasticity is one of the key factors leading to post-stroke depression; however, the precise molecular mechanisms remain unclear. |
2023-07-31 |
2023-08-14 |
Not clear |
| Ning Sun, Wen-Qiang Cui, Xiao-Man Min, Guang-Ming Zhang, Jia-Zheng Liu, Hong-Yun W. A new perspective on hippocampal synaptic plasticity and post-stroke depression. The European journal of neuroscience. 2023-07-31. PMID:37518943. |
this review further elaborates on the role of hippocampal synaptic plasticity in post-stroke depression by summarizing recent research and analysing possible molecular mechanisms. |
2023-07-31 |
2023-08-14 |
Not clear |
| Ning Sun, Wen-Qiang Cui, Xiao-Man Min, Guang-Ming Zhang, Jia-Zheng Liu, Hong-Yun W. A new perspective on hippocampal synaptic plasticity and post-stroke depression. The European journal of neuroscience. 2023-07-31. PMID:37518943. |
evidence for the correlation between hippocampal mechanisms and post-stroke depression helps to better understand the pathological process of post-stroke depression and improve its treatment. |
2023-07-31 |
2023-08-14 |
Not clear |
| Pu Yang, Haiyan Chen, Tian Wang, Ling Li, Hong Su, Jing Li, Yujun He, Shengyong S. Electroacupuncture Attenuates Chronic Inflammatory Pain And Depression Comorbidity by Inhibiting Hippocampal Neuronal Apoptosis via the PI3K/Akt Signaling Pathway. Neuroscience letters. 2023-07-29. PMID:37516346. |
electroacupuncture attenuates chronic inflammatory pain and depression comorbidity by inhibiting hippocampal neuronal apoptosis via the pi3k/akt signaling pathway. |
2023-07-29 |
2023-08-14 |
rat |
| Pu Yang, Haiyan Chen, Tian Wang, Ling Li, Hong Su, Jing Li, Yujun He, Shengyong S. Electroacupuncture Attenuates Chronic Inflammatory Pain And Depression Comorbidity by Inhibiting Hippocampal Neuronal Apoptosis via the PI3K/Akt Signaling Pathway. Neuroscience letters. 2023-07-29. PMID:37516346. |
this study aimed to investigate the effects of ea on hippocampal neuronal apoptosis in rats with cip and depression. |
2023-07-29 |
2023-08-14 |
rat |
| Pu Yang, Haiyan Chen, Tian Wang, Ling Li, Hong Su, Jing Li, Yujun He, Shengyong S. Electroacupuncture Attenuates Chronic Inflammatory Pain And Depression Comorbidity by Inhibiting Hippocampal Neuronal Apoptosis via the PI3K/Akt Signaling Pathway. Neuroscience letters. 2023-07-29. PMID:37516346. |
overall, our study suggests that ea holds the potential to improve pain and depressive behaviors in rats with cip and depression comorbidity, potentially mediated through the activation of the pi3k/akt pathway, leading to a reduction in hippocampal neuronal apoptosis. |
2023-07-29 |
2023-08-14 |
rat |
| Sahar Mohammadi, Mohsen Naseri, Nassim Faridi, Parisa Zareie, Leila Zare, Javad Mirnajafi-Zadeh, S Zahra Bathai. Saffron carotenoids reversed the UCMS-induced depression and anxiety in rats: Behavioral and biochemical parameters, and hippocampal BDNF/ERK/CREB and NR2B signaling markers. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 119. 2023-07-28. PMID:37506574. |
saffron carotenoids reversed the ucms-induced depression and anxiety in rats: behavioral and biochemical parameters, and hippocampal bdnf/erk/creb and nr2b signaling markers. |
2023-07-28 |
2023-08-14 |
rat |
| Hao Li, Xunrong Luo, Kai Qi, Yijie Lv, Junnan Kan, Changfeng Yang, Xiaoqian Lin, Jin Tao, Wei Zhang, Yan Liu, Kang Rong, Ailing Wang, Zhongde Jiang, Xianglin L. Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model. Journal of magnetic resonance imaging : JMRI. 2023-07-27. PMID:37496196. |
glutamate chemical exchange saturation transfer (glucest) mri to evaluate the rapid antidepressant effects of ketamine in the hippocampus of rat depression model. |
2023-07-27 |
2023-08-14 |
rat |
| Erkan Gökç. Editorial for "Glutamate Chemical Exchange Saturation Transfer (GluCEST) MRI to Evaluate the Rapid Antidepressant Effects of Ketamine in the Hippocampus of Rat Depression Model". Journal of magnetic resonance imaging : JMRI. 2023-07-27. PMID:37496402. |
editorial for "glutamate chemical exchange saturation transfer (glucest) mri to evaluate the rapid antidepressant effects of ketamine in the hippocampus of rat depression model". |
2023-07-27 |
2023-08-14 |
rat |
| Ying He, Man-Shu Zou, Ting-Ting Ren, Ping Li, Yang Liu, Yuan-Shan Ha. [Therapeutic effect and mechanism of Xiaoyao Kangai Jieyu Recipe on mice with breast cancer related depression through regulating COX pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 14. 2023-07-20. PMID:37475079. |
in summary, xkjr may improve hippocampal microglia activation and neuronal damage in mice with breast cancer related depression through activating cox signaling pathway. |
2023-07-20 |
2023-08-14 |
mouse |
| Yongzhi Shan, Hongxing Wang, Yanfeng Yang, Jiahao Wang, Wenfeng Zhao, Yuda Huang, Huang Wang, Bing Han, Na Pan, Xiukun Jin, Xiaotong Fan, Yunyun Liu, Jun Wang, Changming Wang, Huaqiang Zhang, Sichang Chen, Ting Liu, Tianyi Yan, Tianmei Si, Lu Yin, Xinmin Li, Fiammetta Cosci, Xiangyang Zhang, Guanghao Zhang, Keming Gao, Guoguang Zha. Evidence of a large current of transcranial alternating current stimulation directly to deep brain regions. Molecular psychiatry. 2023-07-19. PMID:37468529. |
deep brain regions such as hippocampus, insula, and amygdala are involved in neuropsychiatric disorders, including chronic insomnia and depression. |
2023-07-19 |
2023-08-14 |
human |
| Maria Becker, Denis Gorobets, Elena Shmerkin, Liza Weinstein-Fudim, Albert Pinhasov, Asher Orno. Prenatal SAMe Treatment Changes via Epigenetic Mechanism/s USVs in Young Mice and Hippocampal Monoamines Turnover at Adulthood in a Mouse Model of Social Hierarchy and Depression. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445911. |
prenatal same treatment changes via epigenetic mechanism/s usvs in young mice and hippocampal monoamines turnover at adulthood in a mouse model of social hierarchy and depression. |
2023-07-14 |
2023-08-14 |
mouse |
| Jessica Mingardi, Elona Ndoj, Tiziana Bonifacino, Paulina Misztak, Matteo Bertoli, Luca La Via, Carola Torazza, Isabella Russo, Marco Milanese, Giambattista Bonanno, Maurizio Popoli, Alessandro Barbon, Laura Musazz. Functional and Molecular Changes in the Prefrontal Cortex of the Chronic Mild Stress Rat Model of Depression and Modulation by Acute Ketamine. International journal of molecular sciences. vol 24. issue 13. 2023-07-14. PMID:37445990. |
we have previously used the chronic mild stress (cms) model of depression in male rats to show that cms induces morphological, functional, and molecular changes in the hippocampus of vulnerable animals, the majority of which were recovered using acute subanesthetic ketamine in just 24 h. here, we focused our attention on the medial prefrontal cortex (mpfc), a brain area regulating emotional and cognitive functions, and asked whether vulnerability/resilience to cms and ketamine antidepressant effects were associated with molecular and functional changes in the mpfc of rats. |
2023-07-14 |
2023-08-14 |
rat |
| Minghe Xu, Qian Wang, Bo Li, Shaowen Qian, Shuang Wang, Yu Wang, Chunlian Chen, Zhe Liu, Yuqing Ji, Kai Liu, Kuolin Xin, Yujun Ni. Cerebellum and hippocampus abnormalities in patients with insomnia comorbid depression: a study on cerebral blood perfusion and functional connectivity. Frontiers in neuroscience. vol 17. 2023-07-03. PMID:37397441. |
cerebellum and hippocampus abnormalities in patients with insomnia comorbid depression: a study on cerebral blood perfusion and functional connectivity. |
2023-07-03 |
2023-08-14 |
human |