| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shih-Kai Kevin Lin, Hsi-Chung Chen, Chun-Hsin Chen, I-Ming Chen, Mong-Liang Lu, Cheng-Dien Hsu, Yi-Hang Chiu, Tsung-Yang Wang, Hui-Mei Chen, Yu-Chu Ella Chung, Po-Hsiu Ku. Exploring the human gut microbiota targets in relation to the use of contemporary antidepressants. Journal of affective disorders. 2023-10-11. PMID:37820962. |
antidepressants, specifically selective serotonin reuptake inhibitors (ssris) and serotonin-norepinephrine reuptake inhibitors (snris), are commonly prescribed for depression treatment. |
2023-10-11 |
2023-10-15 |
human |
| Rie Matsushima-Nishiwaki, Shota Kamoi, Osamu Kozaw. Upregulation by duloxetine of the transforming growth factor-α-induced migration of hepatocellular carcinoma cells via enhancement of the c-Jun N-terminal kinase activity. Cell biochemistry and function. vol 41. issue 7. 2023-10-10. PMID:37814477. |
duloxetine, a selective reuptake inhibitor for serotonin and norepinephrine, is a medication widely used for major depression. |
2023-10-10 |
2023-10-15 |
human |
| Yi-Ze Sun, Hai-Bin Zhao, Zhe-Yi Wan. [Mechanism of stress-induced microglial activation in depression and traditional Chinese medicine regulation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 16. 2023-10-06. PMID:37802855. |
cross-talk between impaired microglia function and neurobiological factors such as inflammatory cytokines, serotonin metabolism, and neuroplasticity may lead to depression. |
2023-10-06 |
2023-10-15 |
Not clear |
| Edward R Palmer, Siân Lowri Griffiths, Ben Watkins, Tyler Weetman, Ryan Ottridge, Smitaa Patel, Rebecca Woolley, Sarah Tearne, Pui Au, Eleanor Taylor, Zara Sadiq, Hareth Al-Janabi, Barnaby Major, Charlotte Marriott, Nusrat Husain, Mohammad Zia Ul Haq Katshu, Domenico Giacco, Nicholas M Barnes, James T R Walters, Thomas R E Barnes, Max Birchwood, Richard Drake, Rachel Upthegrov. Antidepressants for the prevention of depression following first-episode psychosis (ADEPP): study protocol for a multi-centre, double-blind, randomised controlled trial. Trials. vol 24. issue 1. 2023-10-06. PMID:37803384. |
sertraline is a selective serotonin reuptake inhibitor and a common first-line medication for the treatment of depression in adults. |
2023-10-06 |
2023-10-15 |
Not clear |
| Dandan Zhan, Xuan Wang, Yifeng Zheng, Shengqi Wang, Bowen Yang, Bo Pan, Neng Wang, Zhiyu Wan. Integrative dissection of 5-hydroxytryptamine receptors-related signature in the prognosis and immune microenvironment of breast cancer. Frontiers in oncology. vol 13. 2023-10-05. PMID:37795441. |
5-hydroxytryptamine (5-ht) plays a key role in the pathogenesis and treatment of depression. |
2023-10-05 |
2023-10-07 |
Not clear |
| Andreas Reif, Istvan Bitter, Jozefien Buyze, Kerstin Cebulla, Richard Frey, Dong-Jing Fu, Tetsuro Ito, Yerkebulan Kambarov, Pierre-Michel Llorca, Albino J Oliveira-Maia, Thomas Messer, Siobhán Mulhern-Haughey, Benoît Rive, Christian von Holt, Allan H Young, Yordan Godino. Esketamine Nasal Spray versus Quetiapine for Treatment-Resistant Depression. The New England journal of medicine. vol 389. issue 14. 2023-10-04. PMID:37792613. |
the efficacy and safety of esketamine nasal spray as compared with extended-release quetiapine augmentation therapy, both in combination with ongoing treatment with a selective serotonin reuptake inhibitor (ssri) or a serotonin-norepinephrine reuptake inhibitor (snri), in patients with treatment-resistant depression are unknown. |
2023-10-04 |
2023-10-07 |
Not clear |
| Alejandro Orrico-Sanchez, Bruno P Guiard, Stella Manta, Jacques Callebert, Jean-Marie Launay, Franck Louis, Antoine Paccard, Carole Gruszczynski, Catalina Betancur, Vincent Vialou, Sophie Gautro. Organic cation transporter 2 contributes to SSRI antidepressant efficacy by controlling tryptophan availability in the brain. Translational psychiatry. vol 13. issue 1. 2023-09-29. PMID:37775532. |
selective serotonin reuptake inhibitors (ssri) are common first-line treatments for major depression. |
2023-09-29 |
2023-10-07 |
mouse |
| Helen Holvoet, Dani M Long, Liping Yang, Jaewoo Choi, Luke Marney, Burkhard Poeck, Claudia S Maier, Amala Soumyanath, Doris Kretzschmar, Roland Straus. Chlorogenic Acids, Acting via Calcineurin, Are the Main Compounds in Nutrients. vol 15. issue 18. 2023-09-28. PMID:37764799. |
drugs used to treat depression mostly aim to increase serotonin signaling but these can have unwanted side effects. |
2023-09-28 |
2023-10-07 |
Not clear |
| Xiaoyan Peng, Sujuan Feng, Poxuan Zhang, Shengmei Sang, Yi Zhan. Analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with BDNF, NT-3 and 5-HT levels. PeerJ. vol 11. 2023-09-26. PMID:37750080. |
analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with bdnf, nt-3 and 5-ht levels. |
2023-09-26 |
2023-10-07 |
Not clear |
| Xiaoyan Peng, Sujuan Feng, Poxuan Zhang, Shengmei Sang, Yi Zhan. Analysis of influencing factors of anxiety and depression in maintenance hemodialysis patients and its correlation with BDNF, NT-3 and 5-HT levels. PeerJ. vol 11. 2023-09-26. PMID:37750080. |
the aim of this study is to examine the factors that contribute to anxiety and depression in individuals undergoing maintenance hemodialysis (mhd), as well as their association with serum levels of brain-derived neurotrophic factor (bdnf), neurotrophin-3 (nt-3), and serotonin (5-ht). |
2023-09-26 |
2023-10-07 |
Not clear |
| Kathryn Justesen, Darien Jourdain. Peripartum Depression: Detection and Treatment. American family physician. vol 108. issue 3. 2023-09-19. PMID:37725459. |
cognitive behavior therapy and interpersonal psychotherapy are the mainstay of treatment for peripartum depression; physicians should consider selective serotonin reuptake inhibitors for those with moderate to severe depression. |
2023-09-19 |
2023-10-07 |
Not clear |
| Yan Wang, Yuzhen Huang, Min Zhao, Lu Yang, Kunhan Su, Hao Wu, Yuting Wang, Qing Chang, Wanli Li. Zuojin pill improves chronic unpredictable stress-induced depression-like behavior and gastrointestinal dysfunction in mice via the theTPH2/5-HT pathway. Phytomedicine : international journal of phytotherapy and phytopharmacology. vol 120. 2023-09-16. PMID:37716030. |
the complex bidirectional communication between the gastrointestinal tract and the brain is associated with mental disorders such as depression; serotonin, as a crucial neurotransmitter in the communication system between the central nervous system and the gastrointestinal tract, has effects on regulating gastrointestinal motility and sensation and improving psychosomatic status. |
2023-09-16 |
2023-10-07 |
mouse |
| Ofelia Limón-Morales, Kenia Morales-Quintero, Marcela Arteaga-Silva, Tania Molina-Jiménez, Marco Cerbón, Herlinda Bonilla-Jaim. Alterations of learning and memory are accompanied by alterations in the expression of 5-HT receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. Behavioural brain research. 2023-09-15. PMID:37714467. |
alterations of learning and memory are accompanied by alterations in the expression of 5-ht receptors, glucocorticoid receptor and brain-derived neurotrophic factor in different brain regions of an animal model of depression generated by neonatally male treatment with clomipramine in male rats. |
2023-09-15 |
2023-10-07 |
rat |
| Nikolas Ros. Commentary: Recent disputes on the role of serotonin in depression. Psychological medicine. 2023-09-12. PMID:37698506. |
commentary: recent disputes on the role of serotonin in depression. |
2023-09-12 |
2023-10-07 |
Not clear |
| Scotti McLaren, Karin Seidler, James Nei. Investigating the Role of 17β-Estradiol on the Serotonergic System, Targeting Soy Isoflavones as a Strategy to Reduce Menopausal Depression: A Mechanistic Review. Journal of the American Nutrition Association. 2023-09-11. PMID:37695875. |
low serotonin is one factor implicated in the development of depression. |
2023-09-11 |
2023-10-07 |
human |
| Naoto Kajitani, Mami Okada-Tsuchioka, Asuka Inoue, Kanako Miyano, Takeshi Masuda, Shuken Boku, Kazuya Iwamoto, Sumio Ohtsuki, Yasuhito Uezono, Junken Aoki, Minoru Takebayash. G protein-biased LPAR1 agonism of prototypic antidepressants: Implication in the identification of novel therapeutic target for depression. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-06. PMID:37673966. |
prototypic antidepressants, such as tricyclic/tetracyclic antidepressants (tcas), have multiple pharmacological properties and have been considered to be more effective than newer antidepressants, such as selective serotonin reuptake inhibitors, in treating severe depression. |
2023-09-06 |
2023-10-07 |
mouse |
| Michael Frazure, In Morimoto, Nathan Fielder, Nicholas Mellen, Kimberly Iceman, Teresa Pitt. Serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model. bioRxiv : the preprint server for biology. 2023-09-04. PMID:37662371. |
serotonin therapies for opioid-induced dysphagia and respiratory depression: sex differences in a rat electromyography model. |
2023-09-04 |
2023-09-07 |
rat |
| Joanna Witoszyńska-Sobkowiak, Dorota Sikorska, Rafał Rutkowski, Karolina Niklas, Iwona Żychowska, Włodzimierz Samborsk. Treatment of ankylosing spondylitis with TNFα inhibitors does not affect serum levels of tryptophan metabolites. Inflammopharmacology. 2023-08-30. PMID:37646896. |
the imbalance between the kynurenine and serotonin pathways can have serious consequences, e.g., depression. |
2023-08-30 |
2023-09-07 |
human |
| Chaoyu Liu, Eivind Ystrom, Tom A McAdam. Long-Term Maternal and Child Outcomes Following Postnatal SSRI Treatment. JAMA network open. vol 6. issue 8. 2023-08-29. PMID:37642961. |
although selective serotonin reuptake inhibitors (ssris) are recommended for postnatal depression treatment, there is a lack of evidence regarding long-term maternal and child outcomes following postnatal ssri treatment. |
2023-08-29 |
2023-09-07 |
Not clear |
| Yuki Higuchi, Hiroyuki Arakaw. Serotonergic mediation of the brain-wide neurogenesis: Region-dependent and receptor-type specific roles on neurogenic cellular transformation. Current research in neurobiology. vol 5. 2023-08-28. PMID:37638344. |
highlighting these 5-ht mechanisms that mediate neurogenic cell production processes in a brain-region-specific manner would provide unique insights into the role of 5-ht in neurogenesis and its associated effects on depression. |
2023-08-28 |
2023-09-07 |
Not clear |