| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Efthalia Angelopoulou, Evangelia Stanitsa, Claire Chrysanthi Karpodini, Anastasia Bougea, Dionysia Kontaxopoulou, Stella Fragkiadaki, Christos Koros, Vasiliki Epameinondas Georgakopoulou, George Fotakopoulos, Yiannis Koutedakis, Christina Piperi, Sokratis G Papageorgio. Pharmacological and Non-Pharmacological Treatments for Depression in Parkinson's Disease: An Updated Review. Medicina (Kaunas, Lithuania). vol 59. issue 8. 2023-08-26. PMID:37629744. |
available pharmacological therapeutic options for depression in pd mainly include selective serotonin reuptake inhibitors, serotonin and norepinephrine reuptake inhibitors, and tricyclic antidepressants; meanwhile, agents acting on dopaminergic pathways used for motor symptoms, such as levodopa, dopaminergic agonists, and monoamine oxidase b (mao-b) inhibitors, may also provide beneficial antidepressant effects. |
2023-08-26 |
2023-09-07 |
Not clear |
| Yasmine Rifai, Nicholas Cassimatis, Bruce Rubenstein M . Depression in Patients With Intracranial Hemorrhage Secondary to Traumatic Brain Injury. Cureus. vol 15. issue 7. 2023-08-21. PMID:37602011. |
this article discusses the prevalence of depression in patients with intracranial hemorrhage (ich) and the relationship of selective serotonin reuptake inhibitor (ssri) use with bleeding risk. |
2023-08-21 |
2023-09-07 |
Not clear |
| Khalid AlHezaimi, Ilan Rotstein, Joseph Katz, Marc Nevins, Myron Nevin. Effect of selective serotonin reuptake inhibitor (paroxetine) on newly formed bone volume: Real time in vivo micro computed tomographic analysis. Journal of endodontics. 2023-08-18. PMID:37595681. |
selective serotonin reuptake inhibitors (ssris) antidepressant are commonly used to treat depression and anxiety. |
2023-08-18 |
2023-10-07 |
Not clear |
| Xiao-Lan Yu, Cui-Ping Li, Lian-Ping H. Vitamin D may alleviate irritable bowel syndrome by modulating serotonin synthesis: a hypothesis based on recent literature. Frontiers in physiology. vol 14. 2023-08-14. PMID:37576336. |
a number of studies found that serotonin plays a vital role in the development of depression and irritable bowel syndrome. |
2023-08-14 |
2023-08-16 |
Not clear |
| Vasileia Kotoula, Jennifer W Evans, Claire E Punturieri, Carlos A Zarat. Review: The use of functional magnetic resonance imaging (fMRI) in clinical trials and experimental research studies for depression. Frontiers in neuroimaging. vol 2. 2023-08-09. PMID:37554642. |
our search results focused on selective serotonin reuptake inhibitors (ssris), the most commonly prescribed treatments for depression and ketamine, a fast-acting antidepressant treatment. |
2023-08-09 |
2023-08-16 |
Not clear |
| Neda H Bidoki, Kristy A Zera, Huda Nassar, Lauren L Drag, Michael Mlynash, Elizabeth Osborn, Muhith Musabbir, Da Eun K Kim, Maria Paula Mendez, Maarten G Lansberg, Nima Aghaeepour, Marion S Buckwalte. Machine learning models of plasma proteomic data predict mood in chronic stroke and tie it to aberrant peripheral immune responses. Brain, behavior, and immunity. 2023-08-09. PMID:37557961. |
we propose that in chronic post-stroke depression there is over-activation of the immune response that then triggers changes in serotonin activity and neuronal plasticity leading to depressed mood. |
2023-08-09 |
2023-08-16 |
human |
| Sandrita Simonyte, Ingrida Grabauskyte, Jurate Macijauskiene, Vita Lesauskaite, Vaiva Lesauskaite, Kari Sofie Kvaal, Robert Stewar. Associations of the serotonin transporter gene polymorphism, 5-HTTLPR, and adverse life events with late life depression in the elderly Lithuanian population. Scientific reports. vol 13. issue 1. 2023-08-09. PMID:37558806. |
associations of the serotonin transporter gene polymorphism, 5-httlpr, and adverse life events with late life depression in the elderly lithuanian population. |
2023-08-09 |
2023-08-16 |
human |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
escitalopram reversibility of the impacts following chronic stress on central 5-ht profiles - implications to depression and anxiety. |
2023-08-06 |
2023-08-14 |
rat |
| Chen-Cheng Lin, Chiu-Ping Yang, Pao-Yun Cheng, Michael Hsiao, Yia-Ping Li. Escitalopram reversibility of the impacts following chronic stress on central 5-HT profiles - Implications to depression and anxiety. Behavioural brain research. 2023-08-06. PMID:37544369. |
later studies suggest both presynaptic and postsynaptic 5-ht profiles should be considered for the effects of ssris, making it difficult to interpret the etiological and therapeutic mechanisms underlying depression and anxiety. |
2023-08-06 |
2023-08-14 |
rat |
| Kyung Hwa Lee, Jiyoon Shin, Jung Lee, Jae Hyun Yoo, Jae-Won Kim, David A Bren. Measures of Connectivity and Dorsolateral Prefrontal Cortex Volumes and Depressive Symptoms Following Treatment With Selective Serotonin Reuptake Inhibitors in Adolescents. JAMA network open. vol 6. issue 8. 2023-08-04. PMID:37540512. |
selective serotonin reuptake inhibitors (ssris) are considered a first-line pharmacological treatment for adolescent depression with moderate or higher levels of symptom severity. |
2023-08-04 |
2023-08-14 |
Not clear |
| Shengyuan Wang, Shaohui Li, Heng Wu, Tongyangzi Zhang, Yixiao Chen, Yiqing Zhu, Siwan Wen, Cuiqin Shi, Li Yu, Xianghuai X. A randomized, double-blinded, placebo-controlled clinical trial of duloxetine hydrochloride enteric-coated tablets in the treatment of refractory chronic cough. BMC pulmonary medicine. vol 23. issue 1. 2023-08-02. PMID:37533019. |
this trail proposes using duloxetine, a selective 5-ht and norepinephrine reuptake inhibitor, as a potential treatment for refractory cough, which has shown promise in treating pain and depression. |
2023-08-02 |
2023-08-14 |
Not clear |
| Tyra Lagerberg, Anthony A Matthews, Nanbo Zhu, Seena Fazel, Juan-Jesus Carrero, Zheng Chan. Effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-07-28. PMID:37507510. |
effect of selective serotonin reuptake inhibitor treatment following diagnosis of depression on suicidal behaviour risk: a target trial emulation. |
2023-07-28 |
2023-08-14 |
Not clear |
| Xiaoke Di, Meiyu Wan, Ya-Nan Bai, Fengjuan Lu, Minghui Zhao, Zhifei Zhang, Yang L. Exploring the mechanism of Icariin in the treatment of depression through BDNF-TrkB pathway based on network pharmacology. Naunyn-Schmiedeberg's archives of pharmacology. 2023-07-20. PMID:37470804. |
in a cums-induced depression model, we found that icariin could effectively improve depression-like behavior of mice, increase the expression of monoamine neurotransmitters 5-hydroxytryptamine, dopamine, and norepinephrine, decrease the secretion of inflammatory factors tumor necrosis factor-α, interleukin-6, and interleukin-1β, and upregulate the relative expression levels of bdnf, p-trkb/trkb, p-akt/akt, p-creb/creb, mapk3, mapk1, bcl-2, egfr, and mtor. |
2023-07-20 |
2023-08-14 |
mouse |
| Karina Bravo, Marcelo González-Ortiz, Sebastian Beltrán-Castillo, Daniela Cáceres, Jaime Eugení. Development of the Placenta and Brain Are Affected by Selective Serotonin Reuptake Inhibitor Exposure During Critical Periods. Advances in experimental medicine and biology. vol 1428. 2023-07-19. PMID:37466774. |
selective serotonin reuptake inhibitors (ssris) are usually prescribed to treat major depression and anxiety disorders. |
2023-07-19 |
2023-08-14 |
Not clear |
| Samina Bano, Humaira Sharif, Faiza Sajid, Sumaiya Binte Hamid, Abdulla A-B Badaw. Liver tryptophan 2,3-dioxygenase: a determinant of anxiety-like behaviour - studies with chronic nicotine administration in rats. Behavioural pharmacology. 2023-07-18. PMID:37462143. |
the present study aimed to examine the relationship between behavioural measures of anxiety and depression with liver tdo activity, brain tryptophan concentration and serotonin synthesis in rats treated chronically with nicotine. |
2023-07-18 |
2023-08-14 |
mouse |
| Yéssica P López-Echeverri, Kelly J Cardona-Londoño, Jhonny F Garcia-Aguirre, Mary Orrego-Cardoz. Effects of serotonin transporter and receptor polymorphisms on depression. Revista Colombiana de psiquiatria (English ed.). 2023-07-15. PMID:37453823. |
effects of serotonin transporter and receptor polymorphisms on depression. |
2023-07-15 |
2023-08-14 |
Not clear |
| Yéssica P López-Echeverri, Kelly J Cardona-Londoño, Jhonny F Garcia-Aguirre, Mary Orrego-Cardoz. Effects of serotonin transporter and receptor polymorphisms on depression. Revista Colombiana de psiquiatria (English ed.). 2023-07-15. PMID:37453823. |
serotonin is highly implicated in the regulation of emotional state and the execution of cognitive tasks, so much so that the serotonin transporter genes (5-htt, slc6a4) and the serotonin receptor genes (htr1a, htr1b, htr2a) have become the perfect candidates when studying the effects that these genes and their polymorphic variations have on depression characteristics. |
2023-07-15 |
2023-08-14 |
Not clear |
| Dat T N Ngo, Tho H Ho, Lam K Huynh, Trang T Nguye. The interplay of membrane fluidity, acyl chain order and area per lipid on the partitioning of two antidepressants paroxetine and sertraline. Soft matter. 2023-07-12. PMID:37435937. |
selective serotonin reuptake inhibitors (ssris) are among the popular drugs for treating depression and mental disorders. |
2023-07-12 |
2023-08-14 |
Not clear |
| Carla Fonseca, Miren Ettcheto, Joana Bicker, Maria José Fernandes, Amílcar Falcão, Antoni Camins, Ana Fortun. Under the umbrella of depression and Alzheimer's disease physiopathology: can cannabinoids be a dual-pleiotropic therapy? Ageing research reviews. 2023-07-06. PMID:37414155. |
besides the well-known imbalance of neurotransmitter levels, including serotonin, noradrenaline, dopamine and glutamate, recent scientific evidence highlights aberrant spine density, neuroinflammation, dysregulation of neurotrophic factor levels and formation of amyloid beta (aβ) peptides, as the main physiopathological mechanisms compromised in depression and ad. |
2023-07-06 |
2023-08-14 |
Not clear |
| Hanga Galfalvy, Eileen Shea, Jacqueline de Vegvar, Spiro Pantazatos, Yung-Yu Huang, Ainsley K Burke, M Elizabeth Sublette, Maria A Oquendo, Francesca Zanderigo, Jeffrey M Miller, J John Man. Brain serotonin 1A receptor binding: relationship to peripheral blood DNA methylation, recent life stress and childhood adversity in unmedicated major depression. The British journal of psychiatry : the journal of mental science. 2023-07-03. PMID:37395098. |
brain serotonin 1a receptor binding: relationship to peripheral blood dna methylation, recent life stress and childhood adversity in unmedicated major depression. |
2023-07-03 |
2023-08-14 |
Not clear |