| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Suhana Datta, Preeti Verma, Bikram Dhara, Rita Kundu, Swastika Maitra, Arup Kumar Mitra, Mohd Shahnawaz Khan, Torki A Zughaibi, Shams Tabrez, Ajoy Kume. Interplay of precision therapeutics and MD study: Calocybe indica's potentials against cervical cancer and its interaction with VEGF via octadecanoic acid. Journal of cellular and molecular medicine. vol 28. issue 8. 2024-04-23. PMID:38652115. |
we observed that ace exerts significant influences on nuclear morphology and cell cycle modulation, further inducing early apoptosis and showcasing prebiotic attributes. |
2024-04-23 |
2024-04-26 |
Not clear |
| Minlong Zhang, Lixin Xi. MicroRNA‑200c‑3p regulates seawater‑induced acute lung injury via ANGII and ACE2/ANG1‑7 pathways. Experimental and therapeutic medicine. vol 26. issue 6. 2023-12-01. PMID:38023366. |
the local angiotensin (ang) system angiotensin converting enzyme (ace)-2/ang1-7/mas axis and angii/angiotensin ii receptor type 1 (at1) play an important role in apoptosis. |
2023-12-01 |
2023-12-07 |
Not clear |
| Minlong Zhang, Lixin Xi. MicroRNA‑200c‑3p regulates seawater‑induced acute lung injury via ANGII and ACE2/ANG1‑7 pathways. Experimental and therapeutic medicine. vol 26. issue 6. 2023-12-01. PMID:38023366. |
the local angiotensin (ang) system angiotensin converting enzyme (ace)-2/ang1-7/mas axis and angii/angiotensin ii receptor type 1 (at1) play an important role in apoptosis. |
2023-11-29 |
2023-12-07 |
Not clear |
| Yanan Ding, Huanhuan Xiu, Yanling Zhang, Miaola Ke, Letao Lin, Huzheng Yan, Pan Hu, Meigui Xiao, Xu He, Tao Zhan. Learning and Investigation of the Role of Angiotensin-Converting Enzyme in Radiotherapy for Nasopharyngeal Carcinoma. Biomedicines. vol 11. issue 6. 2023-06-28. PMID:37371679. |
ace knockdown or inhibition reduced ir-induced dna damage and apoptosis. |
2023-06-28 |
2023-08-14 |
Not clear |
| Xiaohan Huang, Wenxia Fan, Jing Sun, Jiaqing Yang, Yanjun Zhang, Qian Wang, Pingchao Li, Yudi Zhang, Shengnan Zhang, Heying Li, Jianhua Wang, Liqiang Feng, Jincun Zhao, Ling Chen, Qu Linbin. SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril. Antiviral research. 2023-05-19. PMID:37207821. |
sars-cov-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ace inhibitor captopril. |
2023-05-19 |
2023-08-14 |
mouse |
| Xiaohan Huang, Wenxia Fan, Jing Sun, Jiaqing Yang, Yanjun Zhang, Qian Wang, Pingchao Li, Yudi Zhang, Shengnan Zhang, Heying Li, Jianhua Wang, Liqiang Feng, Jincun Zhao, Ling Chen, Qu Linbin. SARS-CoV-2 induces cardiomyocyte apoptosis and inflammation but can be ameliorated by ACE inhibitor Captopril. Antiviral research. 2023-05-19. PMID:37207821. |
furthermore, we found that captopril (hypotensive drugs targeting ace) treatment could alleviate sars-cov-2 induced inflammatory response and apoptosis in cardiomyocytes via inactivating tnf signaling pathways, suggesting captopril may be beneficial for reducing covid-19 associated cardiomyopathy. |
2023-05-19 |
2023-08-14 |
mouse |
| Kubra Koc, Nihal Simsek Ozek, Ferhunde Aysin, Ozlem Demir, Asli Yilmaz, Mehmet Yilmaz, Fatime Geyikoglu, Huseyin Serkan Ero. Hispidulin exerts a protective effect against oleic acid induced-ARDS in the rat via inhibition of ACE activity and MAPK pathway. International journal of environmental health research. 2023-01-10. PMID:36624973. |
the protective effect of hispidulin treatment may act through inhibition of the ace activity and then regulation of inflammatory cytokine level and alteration of apoptosis. |
2023-01-10 |
2023-08-14 |
rat |
| Samar A Antar, Mohamed A Saleh, Ahmed A Al-Karmalaw. Investigating the possible mechanisms of pirfenidone to be targeted as a promising anti-inflammatory, anti-fibrotic, anti-oxidant, anti-apoptotic, anti-tumor, and/or anti-SARS-CoV-2. Life sciences. 2022-10-09. PMID:36209833. |
pfd has been demonstrated to decrease apoptosis, downregulate angiotensin-converting enzyme (ace) receptor expression, reduce inflammation through many routes, and alleviate oxidative stress in pneumocytes and other cells while protecting them from covid-19 invasion and cytokine storm. |
2022-10-09 |
2023-08-14 |
Not clear |
| Grecia E Barriga Montalvo, Luciana Porto de Souza Vandenberghe, Vanete Thomaz Soccol, Júlio Cesar de Carvalho, Carlos Ricardo Socco. The Antihypertensive, Antimicrobial and Anticancer Peptides from Current molecular medicine. vol 20. issue 8. 2021-11-22. PMID:32189592. |
ahps have the ability to work as inhibitors of angiotensin-converting enzyme (ace), and help to control several diseases such as hypertension, obesity, and cardiovascular issues, amps play a crucial role in the immune response, inhibiting the development of pathogens such as bacteria, fungi, viruses and others, while acps can aid in tumour control by the induction of apoptosis or necrosis, or the inhibition of angiogenesis. |
2021-11-22 |
2023-08-13 |
Not clear |
| Mohammad Satari, Fatemeh Javani Jouni, Parviz Abolmaleki, Homa Soleiman. Influence of Static Magnetic Field on HeLa and Huo2 Cells in the Presence of Aloe vera Extract. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue S1. 2021-10-08. PMID:33576207. |
this research aimed to assess the impact of static magnetic field (smf) on apoptosis rate and cell cycle progression in the presence of aloe vera crude extract (ace) in normal (huo2) and cancer cells (hela). |
2021-10-08 |
2023-08-13 |
Not clear |
| Mohammad Satari, Fatemeh Javani Jouni, Parviz Abolmaleki, Homa Soleiman. Influence of Static Magnetic Field on HeLa and Huo2 Cells in the Presence of Aloe vera Extract. Asian Pacific journal of cancer prevention : APJCP. vol 22. issue S1. 2021-10-08. PMID:33576207. |
this increased the cell number in g2/m stage and early apoptosis in cancer cells compared to ace treated cells after 24 and 48h but reduced the number of huo2 cells in g2/m phase and early apoptosis after 24h. |
2021-10-08 |
2023-08-13 |
Not clear |
| Hsin-Wen Liang, Tsung-Yuan Yang, Chia-Sheng Teng, Yi-Ju Lee, Meng-Hsun Yu, Huei-Jane Lee, Li-Sung Hsu, Chau-Jong Wan. Mulberry leaves extract ameliorates alcohol-induced liver damages through reduction of acetaldehyde toxicity and inhibition of apoptosis caused by oxidative stress signals. International journal of medical sciences. vol 18. issue 1. 2021-09-06. PMID:33390773. |
overall, our findings indicated that mle ameliorated acute alcohol-induced liver damages by reducing ace toxicity and inhibiting apoptosis caused by oxidative stress signals. |
2021-09-06 |
2023-08-13 |
Not clear |
| Zekeriya Duzgun, Zuhal Erogl. Role of cardiac drugs and flavonoids on the IRE1-JNK pathway as revealed by re-ranked molecular docking scores, MM/PBSA and umbrella sampling. Journal of biomolecular structure & dynamics. 2021-05-28. PMID:33251987. |
in this study, we investigated interactions of statins, ace inhibitors, antiarrhythmic drugs and flavonoids in ire1, ask1(apoptosis signal-regulating kinase 1) and jnk1 at an atomic level in comparison with their well-known inhibitors. |
2021-05-28 |
2023-08-13 |
Not clear |
| Ruqian Ding, Xianling Ning, Min Ye, Yuxin Yi. Antrodia camphorata extract (ACE)-induced apoptosis is associated with BMP4 expression and p53-dependent ROS generation in human colon cancer cells. Journal of ethnopharmacology. vol 268. 2021-03-05. PMID:33181285. |
antrodia camphorata extract (ace)-induced apoptosis is associated with bmp4 expression and p53-dependent ros generation in human colon cancer cells. |
2021-03-05 |
2023-08-13 |
human |
| Soroush Seifira. Pirfenidone: A novel hypothetical treatment for COVID-19. Medical hypotheses. vol 144. 2020-12-04. PMID:32575019. |
pirfenidone could inhibit apoptosis, downregulate ace receptors expression, decrease inflammation by several mechanisms and ameliorate oxidative stress and hence protect pneumocytes and other cells from covid-19 invasion and cytokine storm simultaneously. |
2020-12-04 |
2023-08-13 |
Not clear |
| Hong Gao, Hai Dong, Guijun Li, Hui Ji. Combined treatment with acetazolamide and cisplatin enhances chemosensitivity in laryngeal carcinoma Hep-2 cells. Oncology letters. vol 15. issue 6. 2020-09-29. PMID:29928333. |
compared with the drugs used alone, treatment with both ace and cis displayed synergistic effects on the growth inhibition and apoptosis induction in hep-2 cells. |
2020-09-29 |
2023-08-13 |
Not clear |
| Oyesiji A Abiodun, Mohammad Shamsul Ol. Role of brain renin angiotensin system in neurodegeneration: An update. Saudi journal of biological sciences. vol 27. issue 3. 2020-09-28. PMID:32127770. |
there is strong evidence for a major involvement of excessive brain angiotensin converting enzyme (ace)/angiotensin ii (ang ii)/angiotensin type-1 receptor (at-1r) axis in increased activation of oxidative stress, apoptosis and neuroinflammation causing neurodegeneration in several brain disorders. |
2020-09-28 |
2023-08-13 |
Not clear |
| Xiujuan Yan, Yingxiu Li, Yun Ho Choi, Chongyang Wang, Yihua Piao, Jing Ye, Jingzhi Jiang, Liangchang Li, Huixian Xu, Qingsong Cui, Guanghai Yan, Minggen Ji. Protective Effect and Mechanism of Alprostadil in Acute Respiratory Distress Syndrome Induced by Oleic Acid in Rats. Medical science monitor : international medical journal of experimental and clinical research. vol 24. 2018-12-12. PMID:30296789. |
conclusions alprostadil has a protective effect on ards induced by oa in rats, possibly through inhibiting apoptosis, suppressing the activation of mapks and nf-κb signaling pathways, and decreasing ace protein expression. |
2018-12-12 |
2023-08-13 |
rat |
| Hui Ma, Jing Kong, Yu-Lin Wang, Jun-Long Li, Nai-Hao Hei, Xin-Ran Cao, Jing-Jing Yang, Wen-Jiang Yan, Wen-Jing Liang, Hong-Yan Dai, Bo Don. Angiotensin-converting enzyme 2 overexpression protects against doxorubicin-induced cardiomyopathy by multiple mechanisms in rats. Oncotarget. vol 8. issue 15. 2018-03-23. PMID:28445944. |
apoptosis, inflammation, oxidative stress, cardiac function, the extent of myocardial fibrosis, and levels of ace2, ace, angiotensin ii (angii), and angiotensin (1-7) were evaluated. |
2018-03-23 |
2023-08-13 |
rat |
| J Bhavana, M K Kalaivani, A Sumath. Cytotoxic and pro-apoptotic activities of leaf extract of Croton bonplandianus Baill. against lung cancer cell line A549. Indian journal of experimental biology. vol 54. issue 6. 2016-09-22. PMID:27468464. |
the acetone extract (ace) of the croton bonplandianus baill., an exotic weed of the euphorbiaceae family was studied for cytotoxicity, apoptosis, cell cycle arrest in a549 cell line and antioxidant capacities using mtt assay, acridine orange/ethidium bromide (ao/eb staining), cell cycle analysis and dpph radical scavenging assay respectively. |
2016-09-22 |
2023-08-13 |
Not clear |