| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ke Wang, Yuanhua Nie, Shilong Wang, Dongmin Chan. Overexpression of lncRNA LINC00294 Induces Cell Cycle Arrest and Apoptosis in Colorectal Cancer by Regulating the miR-499a-5p/LARP4B Axis. Journal of biochemical and molecular toxicology. vol 39. issue 1. 2024-12-24. PMID:39717893. |
protein levels of cell cycle and cell apoptosis markers were measured by western blot analysis. |
2024-12-24 |
2024-12-26 |
mouse |
| Nana Li, Peihua Yan, Ling Guo, Huiyan Wang, Baohong Cui, Lichen Teng, Yajuan S. The small molecule peptide ANXA114-26 inhibits ovarian cancer cell proliferation and reverses cisplatin resistance by binding to the formyl peptide receptors receptor. Journal of cell communication and signaling. vol 19. issue 1. 2024-12-23. PMID:39712859. |
then, we explored the effects and mechanisms of this small molecule peptide on the proliferation, apoptosis, and drug resistance of ovarian cancer resistant cells through cck-8, edu cell proliferation assay, annexin v-fitc/pi assay, western blot,qrt-pcr. |
2024-12-23 |
2024-12-25 |
Not clear |
| Meng Fu, Jing-Jing Yu, Mei-Qiu Yan, Jie Su, Jia-Yi Zheng, Xue-Ling Hu, Gui-Yuan Lyu, Jian-Zhen Che. [Effects of different fractions of Polygonati Rhizoma on reproductive dysfunction in male mice with kidney essence deficiency]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 20. 2024-12-19. PMID:39701740. |
western blot was employed to determine the expression of proteins involved in proliferation and apoptosis in the testicular tissue. |
2024-12-19 |
2024-12-22 |
mouse |
| Yun-Li Tang, Hui-Qiong Zhang, Chen Sun, Dai-Bo Wang, Qiao-Ling Ma, Su-Juan Wang, Jian-Hao Gu, Xiao-Fang Xie, Cheng Pen. [Prediction of anti-gastric cancer effect of Panacis Quinquefolii Radix by network pharmacology and in vivo validation]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 20. 2024-12-19. PMID:39701737. |
immunohistochemistry(ihc), western blot(wb), and quantitative real-time pcr(rt-qpcr) techniques were used to detect the expression of predicted key proteins and genes involved in apoptosis and pyroptosis in tumor tissues. |
2024-12-19 |
2024-12-22 |
mouse |
| Zi-Mo Dong, Ke-Jian Wei, Wen-Long Zhang, Hui-Wen Zhang, Heng-Pu Zhou, Yu-Lan Chen, Gui-Yuan Lyu, Jie S. [Protective effect of Polygonati Rhizoma aqueous extract on gastric mucosal injury in mice induced by overtaking pungent substances and alcohol via TRAF1/ASK1/JNK pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 20. 2024-12-19. PMID:39701734. |
the expression levels of proteins in the tumor necrosis factor receptor(tnfr)-associated factor 1(traf1)/apoptosis signal regulating kinase 1(ask1)/c-jun n-terminal kinase(jnk) pathway were determined by western blot, and those of apoptosis factors were determined by immunofluorescence. |
2024-12-19 |
2024-12-22 |
mouse |
| Ying Jiang, Yan-Li Li, Yu-Zhu Wang, Ye-Cheng Wu, Xiao-Yu L. [Inhibition of PRDX1 protein expression and promotion of apoptosis of colorectal cancer cells by furanodienone via inducing ROS generation from NOX4-derived mitochondria]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 21. 2024-12-19. PMID:39701785. |
the results from western blot and cck-8 analysis suggest that intracellular nox1 and nox4 protein expressions are elevated by fur treatment, and glx351322 effectively reverses the pro-apoptotic effect of fur, while ml171 has a minimal impact on apoptosis rate. |
2024-12-19 |
2024-12-22 |
Not clear |
| Can Li, Zhengdong Liu, Dong Liu, Hui Jiang, Chenglong Bi, Weiwei Sh. Down-regulation of JCAD Expression Attenuates Cardiomyocyte Injury by Regulating the Wnt/β-Catenin Pathway. Folia biologica. vol 70. issue 4. 2024-12-18. PMID:39692577. |
the impacts of jcad on the proliferation or apoptosis of h9c2 cells were explored by cck-8 assay, western blot and tunel staining. |
2024-12-18 |
2024-12-21 |
Not clear |
| Hongjie Tang, Changjiang We. DYNLL1 ubiquitinated and degraded by E3 ligase PRKN regulates cell cycle arrest and apoptosis in lung adenocarcinoma cells. Discover oncology. vol 15. issue 1. 2024-12-18. PMID:39692845. |
to this end, we manipulated the expression of dynll1 and prkn with shrna and/or overexpression to assess their effects on a549 cell phenotypes including cell proliferation, cycle arrest and apoptosis using cck-8 assay, edu staining, colony formation assay, flow cytometry, tunel and western blot. |
2024-12-18 |
2024-12-21 |
Not clear |
| Yan Meng, Xuan-Lin Cai, Shan Cong, Jiao Sun, Yong-Wei Hu, Li Lu. Effect of Aconitum diphtheria on the Proliferation, Apoptosis, and Inflammatory Response of Rheumatoid Arthritis Fibroblast-Like Synoviocytes. Cell biochemistry and function. vol 42. issue 8. 2024-12-17. PMID:39682028. |
subsequently, terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling staining, cell counting kit-8 and western blot were utilized to analyze the apoptosis, proliferation, and nuclear factor kappa-light-chain-enhancer of activated b cells (nf-κb) signaling pathway-related proteins in ra-fls, respectively. |
2024-12-17 |
2024-12-21 |
Not clear |
| Gang Li, Guanbo Zhang, Jinsong Li, Jie Zhang, Zhi Yang, Lin Yang, Jiaxing Wan. High mobility group protein N2 inhibits the progression of hepatocellular carcinoma and the related molecular mechanisms. Cytotechnology. vol 77. issue 1. 2024-12-16. PMID:39676764. |
then, cell apoptosis was detected by flow cytometry, and caspase3 and cleaved-caspase3 were detected using western blot assay. |
2024-12-16 |
2024-12-21 |
Not clear |
| Linfa Guo, Yiqiao Zhao, Xiaojie Bai, Xiaolong Wang, Kuerban Tuoheti, Yuanfei Cao, Yingtong Zuo, Xinhua Zhang, Tongzu Li. RRM2 Is a Putative Biomarker and Promotes Bladder Cancer Progression via PI3K/AKT/mTOR Pathway. Journal of cellular physiology. 2024-12-16. PMID:39676643. |
western blot was employed to investigate alterations in markers associated with epithelial-to-mesenchymal transition (emt), apoptosis, and cell cycle regulation. |
2024-12-16 |
2024-12-21 |
Not clear |
| Wenyuan Cai, Tingting Teng, Xiaoyan Wang, Baihong Li, Xin Gu, Yafeng Zho. Thiolutin Alleviates Cardiotoxic Effects of Doxorubicin by Suppressing NLRP3 Inflammasome in the Mouse Model. Cardiovascular toxicology. 2024-12-11. PMID:39663334. |
apoptosis and pyroptosis-related protein levels were analyzed by western blot. |
2024-12-11 |
2024-12-14 |
mouse |
| Donghua Wang, Long Lv, Jinghu Du, Kui Tian, Yu Chen, Manyu Che. TRIM16 and PRC1 Are Involved in Pancreatic Cancer Progression and Targeted by Delphinidin. Chemical biology & drug design. vol 104. issue 6. 2024-12-05. PMID:39635962. |
cck-8, flow cytometry, transwell, and western blot assays were used to analyze the viability, apoptosis, cell cycle progression, invasion, and pathway change of pc cells. |
2024-12-05 |
2024-12-08 |
mouse |
| Yanji Zhu, Guiling Xie, Fangyan Qi, ShenWei Tang, Wenlong Xu. CD73 alleviates podocytes injury in adriamycin-induced nephrotic syndrome. Tissue & cell. vol 93. 2024-12-05. PMID:39637490. |
cytokines (il-1β, il-18), apoptosis and apoposis-related protein (bax, caspase-3, desmin) levels were measured using elisa assay, flow cytometry and western blot, respectively. |
2024-12-05 |
2024-12-08 |
mouse |
| Luna Su, Shaofeng Wang, Quanwei Li, Pan Guo, Yijin Wu, Lijiao Zhao, Lianmei Hu, Ying Li, Jianying Guo, Hui Zhang, Jiaqiang Pan, Zhaoxin Tang, Jianzhao Lia. Hesperidin alleviates ZBP1-drived PANoptosis induced by copper nanoparticles in immune organs of gallus. Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS). vol 87. 2024-12-05. PMID:39637734. |
additionally, the results of western blot showed that nano-cu exposure activated zbp1-mediated panoptosis in immune organs, with evidenced by the significant up-regulation of zbp1 signal molecule and panoptosis-related proteins (apoptosis: caspase-7, caspase-3, caspase-8; pyroptosis: caspase-1, gsdmd, gsdme; necroptosis: ripk1 and mlkl). |
2024-12-05 |
2024-12-08 |
Not clear |
| Qiong Duan, Mingxiao Wang, Zhenting Cui, Jianxin M. Saikosaponin D suppresses esophageal squamous cell carcinoma via the PI3K-AKT signaling pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2024-12-05. PMID:39638887. |
the cck-8, colony formation, wound healing, transwell, apoptosis, and western blot assays were performed to verify the inhibitory ssd impact on eca-109 and te-10 cells. |
2024-12-05 |
2024-12-08 |
human |
| Sheng-Yu Shi, Liang-Wei Zhao, Chong-Bing Liu, Hua-Ming Xiao, Zhong-Jun Jian. Pirfenidone promotes cell cycle arrest and apoptosis of triple‑negative breast cancer cells by suppressing Hedgehog/GLI1 signaling. Naunyn-Schmiedeberg's archives of pharmacology. 2024-12-02. PMID:39621085. |
the levels of proteins associated with cell cycle, apoptosis and hedgehog/gliomaassociated oncogene homolog (gli)1 signaling was examined through western blot. |
2024-12-02 |
2024-12-06 |
Not clear |
| Xinzhu Wu, Pan Huang, Yanmin Xiao, Lin Zha, Jingguo Ma, Hongli Xia. METTL14 Promotes Lipopolysaccharide-Induced Myocardial Damage via m6A-Dependent Stabilization of TRPM7 mRNA. International heart journal. vol 65. issue 6. 2024-12-01. PMID:39617501. |
meanwhile, the protein levels of trpm7, mettl14, phospho-p65 (p-p65), total p65 (p65), p-iκbα, and total iκbα (iκbα) were examined via western blot assay.lps treatment repressed ac16 cell viability and induced cell apoptosis, inflammatory response, oxidative stress, and ferroptosis in vitro. |
2024-12-01 |
2024-12-06 |
human |
| Jie Zhang, Yanyan Cu. Synergistic inhibition of proliferation and induction of apoptosis in oral tongue squamous cell carcinoma by mebendazole and paclitaxel via PI3K/AKT pathway mitigation. Naunyn-Schmiedeberg's archives of pharmacology. 2024-11-30. PMID:39614899. |
cell viability, apoptosis, cell cycle distribution, and the expression of pi3k, p-pi3k, akt, and p-akt were evaluated by cell counting kit-8 (cck-8), flow cytometry, and western blot, respectively. |
2024-11-30 |
2024-12-06 |
human |
| Yuchen Wang, Danni Zhao, Xiaolin Non. Artesunate alleviates radiation-induced submandibular gland epithelial cell damage in rats by reducing inflammation and apoptosis. Cell biology international. 2024-11-28. PMID:39607036. |
rt-pcr and western blot analysis of apoptosis cytokines bax/bcl-2 and caspase-3 confirmed these findings. |
2024-11-28 |
2024-11-30 |
rat |