| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kaushalkumar Chaudhari, Vihas T Vasu, Aparna Golani, Afridi Shaikh, Nidhi Nagariya, Hetal Ro. Interferon Induced Upregulation of Tripartite Motif 34 (TRIM34) Leads Apoptotic Cell Death in Lung Adenocarcinoma. Journal of biochemical and molecular toxicology. vol 38. issue 12. 2024-11-28. PMID:39607040. |
the regulatory role of trim34 on ifn-γ exposure was studied by qrt-pcr, western blot analysis, immunocytochemistry, apoptosis assay and scratch assay. |
2024-11-28 |
2024-11-30 |
Not clear |
| Chen Lu, Chao Chen, Yingpeng Xu, Dingyuan Dai, Chen Sun, Qi L. Activation of Wnt/β-catenin signaling to increase B lymphoma Moloney murine leukemia virus insertion region 1 by lithium chloride attenuates the toxicity of cisplatin in the HEI-OC1 auditory cells. Toxicology letters. 2024-11-28. PMID:39608515. |
the appropriate experimental concentrations for each drug were selected by cck-8 cell proliferation assay and western blot to detect apoptosis. |
2024-11-28 |
2024-12-01 |
Not clear |
| Marília I Figueira, Ricardo Marques, Henrique J Cardoso, Lara R S Fonseca, Ana P Duarte, Samuel Silvestre, Sílvia Socorr. Effect of Diosgenin in Suppressing Viability and Promoting Apoptosis of Human Prostate Cancer Cells: An Interplay with the G Protein-Coupled Oestrogen Receptor? International journal of molecular sciences. vol 25. issue 22. 2024-11-27. PMID:39596074. |
apoptosis was enhanced in diosgenin-treated cells, based on the increased caspase-3-like activity, underpinned by the altered expression of apoptosis regulators evaluated by western blot analysis, which indicated the activation of the extrinsic pathway. |
2024-11-27 |
2024-11-29 |
human |
| Xueqi Hou, Longfei Qu, Yong Xu, Jie Liu, Jianlian Gu. Anti-tumor activity of butorphanol in colorectal cancer via targeting SIGMAR1. Discover oncology. vol 15. issue 1. 2024-11-26. PMID:39589602. |
the expressions of proteins implicated in proliferation, metastasis as well as apoptosis were ascertained by western blot. |
2024-11-26 |
2024-11-28 |
Not clear |
| Yingjie Yue, Pingping Chen, Chongwen Re. Piezo1 Modulates Neuronal Autophagy and Apoptosis in Cerebral Ischemia-Reperfusion Injury Through the AMPK-mTOR Signaling Pathway. Neurochemical research. vol 50. issue 1. 2024-11-25. PMID:39585469. |
the effects on cell viability, apoptosis, and autophagy were assessed using cck-8 assays, pi-annexin/v staining combined with flow cytometry, and western blot analysis. |
2024-11-25 |
2024-11-27 |
Not clear |
| Xiaomeng Zha, Man Fang, Wen Zhong, Liang Chen, Hui Feng, Min Zhang, Hui Wang, Yuanzhen Zhan. Dose-, stage- and sex- difference of prenatal prednisone exposure on placental morphological and functional development. Toxicology letters. 2024-11-23. PMID:39580039. |
in the placentas at some doses, there were decreases in cell proliferation markers measured at the rna and protein level by western blot and increased apoptosis. |
2024-11-23 |
2024-11-26 |
mouse |
| Zijuan Xu, Jinling Luan, Fengyun Wan, Meijie Zhang, Fei Ding, Ling Yang, Shuxin Da. Vitamin D promotes autophagy to inhibit LPS-induced lung injury via targeting cathepsin D. Naunyn-Schmiedeberg's archives of pharmacology. 2024-11-21. PMID:39570382. |
cell viability was detected using cell counting kit-8 (cck-8) method, and cell apoptosis was detected using flow cytometry and western blot. |
2024-11-21 |
2024-11-23 |
Not clear |
| Xinlu Xu, Tanfang Zhou, Alimu Tulahong, Rexiati Ruze, Yingmei Sha. Exploring the effects of hypoxia and reoxygenation time on hepatocyte apoptosis and inflammation. PloS one. vol 19. issue 11. 2024-11-21. PMID:39570857. |
the human normal liver cell line hl-7702 iri model was constructed by hypoxia chamber, and the inflammation and apoptosis focal levels of cells were detected by enzyme-linked immunosorbent assay, western blot and quantitative reverse transcription polymerase chain reaction. |
2024-11-21 |
2024-11-24 |
human |
| Fangrui Lin, Junmin Shen, Hangyu Li, Li Li. β-carboline compound-10830733 suppresses the progression of non-small cell lung cancer by inhibiting the PI3K/Akt/GSK 3β signaling pathway. European journal of pharmacology. 2024-11-20. PMID:39566811. |
furthermore, network pharmacological analysis and western blot confirmed that 10830733 inhibits the pi3k/akt/gsk 3β pathway, and that the pi3k inhibitor ly294002 enhances the effects of 10830733 on proliferation, invasion, apoptosis, s and g2 phase arrest, and the expression of pi3k/akt/gsk 3β related proteins. |
2024-11-20 |
2024-11-23 |
Not clear |
| Dexin Zhang, Juanjuan Song, Jie Zhan, Yi Wang, Junyi Deng, Ying Den. The impact of ulinastatin on lymphocyte apoptosis and autophagy in sepsis patients. Scientific reports. vol 14. issue 1. 2024-11-20. PMID:39567616. |
various experimental techniques including hoechst staining, transmission electron microscopy, and western blot analysis were utilized to assess lymphocyte apoptosis, autophagy, and related protein expression levels. |
2024-11-20 |
2024-11-23 |
Not clear |
| Łukasz Biegała, Małgorzata Statkiewicz, Arkadiusz Gajek, Izabela Szymczak-Pajor, Natalia Rusetska, Agnieszka Śliwińska, Agnieszka Marczak, Michał Mikula, Aneta Rogalsk. Molecular mechanisms restoring olaparib efficacy through ATR/CHK1 pathway inhibition in olaparib-resistant BRCA1/2 Biochimica et biophysica acta. Molecular basis of disease. 2024-11-18. PMID:39557132. |
proliferation, apoptosis, atr/chk1 activity, parp signaling, dna damage response (ddr), epithelial-to-mesenchymal transition (emt), and mdr1 expression, were examined via rt-qpcr, western blot, and immunohistochemistry. |
2024-11-18 |
2024-11-22 |
Not clear |
| Xiyuan Hu, Hongdou Liu, Tiao Luo, Ling Chen, Ting Peng, Min Wen, Wensong Luo, Qunfang Xu, Yuanzhu Xie, Mo Li, Mingquan Liu, Xiaohe Liu, Suyou Liu, Shuaiwen Zhu, Zizheng Zou, Zhiyong Lu. Naphthoquinone-derived ZSW-4B induces apoptosis in triple-negative breast cancer via AMPK signalling activation. Scientific reports. vol 14. issue 1. 2024-11-18. PMID:39558000. |
flow cytometry and western blot analysis revealed that zsw-4b induces apoptosis in tnbc cells. |
2024-11-18 |
2024-11-22 |
mouse |
| Cheng Wang, Ping Wang, Jialei Fu, Zongtong Yang, Haitao Du, Mengru Zhang, Shuyu Zhang, Mingyue Shen, Tingting Wang, Kai Wei, Ruiliang Zh. Pinus massoniana pollen polysaccharides alleviate LPS-induced myocardial injury through p110β-mediated inhibition of the PI3K/AKT/NFκB pathway. International journal of biological macromolecules. 2024-11-17. PMID:39551317. |
in this study, we aimed to investigate the impact of ppps on smi, myocardial enzyme levels, pathological changes, oxidative stress, cell apoptosis, and related signaling pathways in lps-induced smi models were observed by hematoxylin-eosin (he) staining, immunohistochemical (ihc) staining, qpcr, western blot analysis, with a particular focus on anti-inflammatory effects of ppps. |
2024-11-17 |
2024-11-22 |
Not clear |
| Yanxue Zhu, Xingzhi Lv, Ruifang Li, Zihan Gao, Chanhao Lei, Lan Wang, Sanqiang L. Saikosaponin-b2 Regulates the Proliferation and Apoptosis of Liver Cancer Cells by Targeting the MACC1/c-Met/Akt Signalling Pathway. Advances in pharmacological and pharmaceutical sciences. vol 2024. 2024-11-15. PMID:39544485. |
meanwhile, annexin v-fitc/pi staining and western blot analysis of cleaved caspase 9 and cleaved caspase 3 demonstrated that ss-b2 induced apoptosis of hepg2 liver cancer cells. |
2024-11-15 |
2024-11-17 |
mouse |
| Zhao Li, Ya-Hong Wu, Ye-Qing Guo, Xiao-Jia Min, Ying Li. Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathway. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. 2024-11-14. PMID:39539173. |
rt-pcr and western blot analyses, flow cytometry, cck8 assay, and immunofluorescence were utilized to investigate the effects of tasquinimod on gene expression, cell cycle, apoptosis, viability, and protein levels in oc cells. |
2024-11-14 |
2024-11-17 |
mouse |
| Ning Tang, Nuojin Geng, Xinhua Zh. Evaluation of Xihuang Pill in inducing pyroptosis in glioma cells through modulation of miR-21-5p. 3 Biotech. vol 14. issue 12. 2024-11-14. PMID:39529806. |
cell viability was measured using the cck-8 assay, apoptosis was detected by flow cytometry, and expression levels of p-stat3/stat3 and pyroptosis-related proteins were determined by western blot. |
2024-11-14 |
2024-11-17 |
human |
| Kebei Xie, Yanli Wang, Zimin Che. Mechanism of the combined action of green tea polyphenols and concurrent radiochemotherapy in regulating GSK-3β to treat non-small cell lung cancer through the Wnt∕β-catenin pathway. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 65. issue 3. 2024-11-12. PMID:39529343. |
the cell viability was assessed using the cell counting kit-8 (cck-8) assay, proliferation was examined through the colony formation assay, apoptosis was monitored via flow cytometry, cell migration, and epithelial-mesenchymal transition (emt)-associated proteins (e-cadherin, n-cadherin) were determined by western blot. |
2024-11-12 |
2024-11-17 |
human |
| Xingli Tan, Xiaoli Su, Ying Wang, Weiwei Liang, Di Wang, Di Huo, Hongyong Wang, Yan Qi, Wenmo Zhang, Ling Han, Dongmei Zhang, Ming Wang, Jing Xu, Honglin Fen. BRD7 regulates cellular senescence and apoptosis in ALS by modulating p21 expression and p53 mitochondrial translocation respectively. Neuroscience. vol 563. 2024-11-10. PMID:39510439. |
we analyzed rna levels using qrt-pcr, protein levels through immunofluorescence and western blot, and apoptosis via tunel staining. |
2024-11-10 |
2024-11-16 |
Not clear |
| Wenbo Shi, Tongyangzi Zhang, Li Zhang, Wanzhen Li, Zhiwei Chen, Xianghuai X. MLLT3 knockdown suppresses proliferation and cell mobility in human lung adenocarcinoma. Drug development research. vol 85. issue 7. 2024-11-06. PMID:39503060. |
specific markers of apoptosis, cell cycle, epithelial-mesenchymal transition (emt), and mllt3-induced signaling were examined by western blot. |
2024-11-06 |
2024-11-08 |
human |
| Alok Kumar Pandey, Vishal Trived. Heat shock protein HSPA8 impedes hemin-induced cellular-toxicity in liver. Toxicology in vitro : an international journal published in association with BIBRA. 2024-11-01. PMID:39486598. |
western blot analysis revealed that hemin triggers both the extrinsic and intrinsic pathways of apoptosis in hepg2 cells. |
2024-11-01 |
2024-11-05 |
Not clear |