| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Marta Henklewska, Aleksandra Pawlak, Bożena Obmińska-Mrukowic. Targeting ATR Kinase as a Strategy for Canine Lymphoma and Leukaemia Treatment. Veterinary and comparative oncology. 2024-09-20. PMID:39300906. |
further, we estimated the level of apoptosis in berzosertib-treated cells via flow cytometry and assessed h2ax phosphorylation as a marker of dna damage using western blot technique. |
2024-09-20 |
2024-09-22 |
human |
| Feng Hu, Senbo Yan, Li Lin, Xiaoxia Qiu, Xinghe Lin, Weiwei Wan. Sacubitril/valsartan attenuated myocardial inflammation, fibrosis, apoptosis and promoted autophagy in doxorubicin-induced cardiotoxicity mice via regulating the AMPKα-mTORC1 signaling pathway. Molecular and cellular biochemistry. 2024-09-20. PMID:39304614. |
a variety of techniques were used to investigate cardiac inflammation, fibrosis, apoptosis, and autophagy, including western blot, real-time quantitative pcr (rt-qpcr), immunohistochemistry, and fluorescence. |
2024-09-20 |
2024-09-23 |
mouse |
| Menglan Liu, Zuoxiao Li, Zhiyu Lv, Yang Xi. Discussion of spinal cord neurons apoptosis and neuroprotection mechanism of NGF gene transfection mediated by recombinant adenovirus in EAE mice. Scientific reports. vol 14. issue 1. 2024-09-17. PMID:39289437. |
aqthe tunel method was employed to observe spinal neuron apoptosis in each group of mice; protein immunoblotting (western blot) and rt-pcr were used to measure ngf levels in the spinal cord tissues of each group, and western blotting was used to assess levels of cleaved caspase-3, bax, and bcl-2. |
2024-09-17 |
2024-09-20 |
mouse |
| Surya P Singh, Gopal Pathuri, Adam S Asch, Chinthalapally V Rao, Venkateshwar Madk. Stat3 Inhibitors TTI-101 and SH5-07 Suppress Bladder Cancer Cell Survival in 3D Tumor Models. Cells. vol 13. issue 17. 2024-09-14. PMID:39273033. |
western blot analysis was performed to evaluate the pharmacodynamic markers involved in cell proliferation, apoptosis, cancer stem cells (cscs), and stat3 signaling in bca. |
2024-09-14 |
2024-09-16 |
mouse |
| Feng-Xia Qu, Xiao Guo, Xiao-Jun Liu, Shu-Wen Zhang, Yue Xin, Jing-Yuan Li, Rong Wang, Chen-Ji Xu, Hai-Ying Li, Chang-Hong L. Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway. Archives of biochemistry and biophysics. 2024-09-13. PMID:39271097. |
changes in reactive oxygen species (ros) levels, mitochondrial membrane potential (ΔΨm), apoptosis and nrf2/ho-1 pathway were analyzed by ros kit, jc-1 kit, tunel assay, western blot and immunohistochemistry. |
2024-09-13 |
2024-09-16 |
rat |
| Gengshui Zhao, Yongqi Fu, Chao Yang, Xuehui Yang, Xiaoxiao H. Identification and Validation of Endoplasmic Reticulum Stress-Related Gene in Traumatic Brain Injury. Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-09-12. PMID:39264510. |
western blot suggested tbhq pretreatment could diminish ers and reduce the protein expressions of apoptosis in the primary cultured neuron injury model. |
2024-09-12 |
2024-09-14 |
Not clear |
| Palati Tuerxun, Takkun Ng, Jiadong Sun, Farong Ou, Xiaoshi Jia, Ke Zhao, Ping Zh. Lipoxin A4 modulates the PKA/CREB and NF-κB signaling pathway to mitigate chondrocyte catabolism and apoptosis in temporomandibular joint osteoarthritis. Experimental cell research. 2024-09-11. PMID:39260675. |
the viability of chondrocytes treated with lxa4 was evaluated with the cell counting kit-8 (cck-8) assay, while protein levels were assessed by western blot analysis, and the apoptosis rate was evaluated with terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick-end labelling (tunel) staining. |
2024-09-11 |
2024-09-14 |
rat |
| Zeynep Akgun, Eda Dogan, Cumali Degirmenci, Ozlem Ozkaya Akagunduz, Mustafa Esassolak, Vildan Bozok, Melis Palama. Evaluation of the Effects of Vitamin D Analogs, Bevacizumab, and Radiotherapy in Uveal Melanoma Cells. Experimental eye research. 2024-09-11. PMID:39260786. |
annexin v/pi staining and western blot analyses for caspase-3, -8, and -9 were performed to analyze apoptosis. |
2024-09-11 |
2024-09-14 |
Not clear |
| Chun-Wen Lan, Hsin-Hung Chen, Jim Jinn-Chyuan She. Deoxyelephantopin induces apoptosis and cell cycle arrest in GL261 glioblastoma cells. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-10. PMID:39254878. |
western blot analysis examined apoptosis and cell cycle-related proteins. |
2024-09-10 |
2024-09-13 |
mouse |
| Yongya Zhang, Fei Wu, Sibei Guo, Ruijie Yin, Min Yuan, Xue Li, Xueru Zhao, Xiaohua L. Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells. Journal of cellular physiology. 2024-09-06. PMID:39238182. |
western blot analysis, quantitative reverse transcriptase-polymerase chain reaction (qrt-pcr), and immunofluorescence analysis were conducted to measure the protein levels associated with apoptosis, cell cycle and emt. |
2024-09-06 |
2024-09-08 |
human |
| Fa-Lin Wang, Xiaoxia Chang, Yuanyang Shi, Tingting Yang, Juan Li, Hongwei Dong, Qi Wang, Shujun Zhang, Jiaren Li. β-Ionone enhances the inhibitory effects of 5-fluorouracil on the proliferation of gastric adenocarcinoma cells by the GSK-3β signaling pathway. PloS one. vol 19. issue 9. 2024-09-06. PMID:39241034. |
the effects of bi and 5-fu alone or their combination on the cell viability, apoptosis, and mitochondrial membrane potential, the cell cycle, and its related proteins-cyclin d1, and cdk4 as well as pcna and gsk-3β were evaluated in sgc-7901 cells and mkn45 cells by mtt, mb, flow cytometry and western blot. |
2024-09-06 |
2024-09-09 |
mouse |
| Kaiping Zhang, Xiang Fang, Ye Zhang, Yin Zhang, Min Cha. Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis. Cell death discovery. vol 10. issue 1. 2024-09-06. PMID:39242558. |
apoptosis-related proteins were evaluated using western blot analysis, and cell apoptosis was measured using flow cytometry. |
2024-09-06 |
2024-09-10 |
rat |
| Kaiping Zhang, Xiang Fang, Ye Zhang, Yin Zhang, Min Cha. Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis. Cell death discovery. vol 10. issue 1. 2024-09-06. PMID:39242558. |
apoptosis-related proteins were detected using western blot analysis, and cellular apoptosis was examined using cell flow cytometry and tunel staining. |
2024-09-06 |
2024-09-10 |
rat |
| Yang Zhao, Liyong Deng, Yi Xie, Weiming Wang, Qin Chai, Guihua Wan. circRACGAP1 Promotes Proliferation of Non-Small Cell Lung Cancer Cells through the miR-1296/CDK2 Pathway. Folia biologica. vol 70. issue 2. 2024-09-04. PMID:39231318. |
the function of circracgap1 in nsclc cell proliferation and apoptosis was investigated using the cck-8 assay, flow cytometry, tunel staining, and western blot. |
2024-09-04 |
2024-09-08 |
Not clear |
| Hongyang Zhu, You Yu, Yuting Li, Shiyao Chang, Yuhui Li. Puerarin ameliorates high glucose-induced MIN6 cell injury by activating PINK1/Parkin-mediated mitochondrial autophagy. Heliyon. vol 10. issue 16. 2024-09-03. PMID:39224278. |
furthermore, gene and protein expression levels of the pink/parkin-mediated mitochondrial autophagy pathway and mitochondrial apoptosis pathway were assessed using real-time quantitative polymerase chain reaction (rt-qpcr) and western blot, respectively. |
2024-09-03 |
2024-09-05 |
Not clear |
| Yuling Zhang, Yanan Wang, Xizhen Cheng, Haochuan Guo, Donglai Ma, Yongxing Song, Yajing Zhang, Hongfang Wang, Huiru D. Cardioprotective Effects of Phlorizin on Hyperlipidemia-induced Myocardial Injury: Involvement of Suppression in Pyroptosis via Regulating HK1/NLRP3/Caspase-1 Signaling Pathway. Applied biochemistry and biotechnology. 2024-09-02. PMID:39223343. |
we also employed electron microscopy to examine myocardial ultrastructural changes and conducted western blot analyses to assess apoptosis factors and pyroptosis markers. |
2024-09-02 |
2024-09-05 |
rat |
| Huaijuan Liu, Peijun Zhang, Jingwen Yu, Jiwei Wang, Jiezhong Yu, Minfang Gu. [Fasudil improves cognitive function in APP/PS1 transgenic mice by promoting mitophagy and inhibiting NLRP3 inflammasome activation]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 40. issue 8. 2024-08-31. PMID:39215667. |
terminal deoxynucleotidyl transferase-mediated dutp-biotin nick end labeling assay (tunel) staining was used to detect neuronal apoptosis; the expression of p62 and nlrp3 was detected by immunofluorescence histochemical staining; real time fluorescence quantitative pcr was used to detect the mrna expression levels of phosphatase and tensin homolog deleted on chromosome ten (pten) -induced putative kinase 1 (pink1), parkin and nlrp3; western blot analysis was used to detect the expression of pink1, parkin, p62, microtubule-associated protein 1 light chain 3 (lc3), nlrp3, adapter protein apoptosis-associated speck-like protein (asc) and interleukin-18 (il-18). |
2024-08-31 |
2024-09-04 |
mouse |
| Chaojie Li, Kan Wang, Jian Fang, Lin Qin, Qiong Ling, Yu Y. TRIM25 activates Wnt/β-catenin signalling by destabilising MAT2A mRNA to drive thoracic aortic aneurysm development. Human molecular genetics. 2024-08-31. PMID:39216871. |
the effects of mat2a, shmat2a, shtrim25 and/or wnt inhibitor (iwr-1) on the viability, apoptosis and protein expressions of vsmcs were examined by cck-8, annexin v-fitc/pi and western blot assays. |
2024-08-31 |
2024-09-04 |
mouse |
| Cui Jiajing, Yan Shuqi, Ma Haoyan, Wang Pingwei, Liu Dongge, Liu Yanping, Chen Qianqian, Fajrin Saleh, Ren Shupin. Perfluorooctane sulfonate causes damage to L-02 cells via Wnt/β-catenin signal path and endoplasmic reticulum stress pathway. Toxicology and industrial health. 2024-08-31. PMID:39217409. |
in this study, we used the cck-8 method to detect cell viability, a microscope and dapi staining to observe cell morphology, flow cytometry to detect cell ros and apoptosis levels; and western blot to detect the expressions of proteins in the wnt/β-catenin, endoplasmic reticulum stress and apoptosis-related pathways. |
2024-08-31 |
2024-09-04 |
human |
| Tingting Liu, Enhua Zhang, Shichao Cui, Haoyu Dai, Xiaohui Yang, Cunzhi Li. Effects of 630 nm laser on apoptosis, metastasis, invasion and epithelial-to-mesenchymal transition of human lung squamous cell carcinoma H520 cells mediated by hematoporphyrin derivatives. Lasers in medical science. vol 39. issue 1. 2024-08-30. PMID:39210165. |
cell proliferation was assessed using cck8 assay; cell apoptosis was detected by hoechst 33258 staining and flow cytometry; cell migration and invasion abilities were evaluated using wound-healing and invasion assays; and protein and mrna expressions were analyzed by western blot and reverse transcription-polymerase chain reaction (rt-pcr) respectively. |
2024-08-30 |
2024-09-04 |
human |