| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qionghua Hu, Lingqin Qiu, Li Ge, Yi We. Sevoflurane postconditioning alleviates hypoxic-ischemic brain damage in rats by inhibiting the endoplasmic reticulum stress PERK/ATF4/CHOP pathway. Tissue & cell. vol 86. 2024-01-09. PMID:38194851. |
additionally, nissl staining assessed hippocampal ca1 area neuronal density, tunel staining evaluated hippocampal ca1 area neuronal apoptosis, and western blot determined hippocampal ca1 area protein levels, including bax, bcl-2, p-perk/perk, p-eif2/eif2, atf4, chop, grp78, bax, and bcl-2 protein levels. |
2024-01-09 |
2024-01-13 |
rat |
| Saurabh Shah, Paras Famta, Rahul Kumar, Anamika Sharma, Ganesh Vambhurkar, Giriraj Pandey, Gurpreet Singh, Prakash Kumar, Ankit Mehra, Atul Mourya, Dadi A Srinivasarao, Akshay Shinde, Sajja Bhanu Prasad, Dharmendra Kumar Khatri, Jitender Madan, Saurabh Srivastav. Quality by design fostered fabrication of cabazitaxel loaded pH-responsive Improved nanotherapeutics against prostate cancer. Colloids and surfaces. B, Biointerfaces. vol 234. 2024-01-05. PMID:38181691. |
western blot studies revealed an elevation in caspase-1 and suppression in bcl-2 indicating enhanced apoptosis compared to the control group. |
2024-01-05 |
2024-01-08 |
Not clear |
| Sheng Wang, Bang-Shuo Zhang, Yi Yang, Lin-Lin F. CircFN1 promotes acute myeloid leukemia cell proliferation and invasion but refrains apoptosis via miR-1294/ARHGEF10L axis. The Kaohsiung journal of medical sciences. 2024-01-05. PMID:38180276. |
cck-8 was used to detect cell proliferation, transwell to cell invasion, tunel staining and flow cytometry to detect cell apoptosis, rt-qpcr to circfn1 rna, mir-1294, and arhgef10l expression levels in hl-60 cells, and western blot to arhgef10l protein expression level in hl-60 cells. |
2024-01-05 |
2024-01-07 |
Not clear |
| Chunyan Wu, Qiao Song, Sophie Gao, Shaoling W. Targeting HDACs for diffuse large B-cell lymphoma therapy. Scientific reports. vol 14. issue 1. 2024-01-03. PMID:38168914. |
chidamide was found to have a cytotoxic effect on dlbcl cells in a dose-dependent manner, while transcriptome analysis and western blot revealed that using it for treatment impacted several biological processes, including pi3k/akt signaling, mtor signaling, the cell cycle, and apoptosis pathways. |
2024-01-03 |
2024-01-06 |
Not clear |
| Cairui Li, Shuguang Sun, Yanmei Zhuang, Zhaokui Luo, Guangquan Ji, Zhong Li. CTSB Nuclear Translocation Facilitates DNA Damage and Lysosomal Stress to Promote Retinoblastoma Cell Death. Molecular biotechnology. 2023-12-30. PMID:38159170. |
real-time quantitative polymerase chain reaction (rt-qpcr), western blot analysis, a comet assay, a cell counting kit-8 (cck-8) assay and flow cytometry were used to measure the levels of the interrelated genes and proteins and to evaluate alterations in autophagy, apoptosis, proliferation, dna damage and cell cycle arrest. |
2023-12-30 |
2024-01-05 |
mouse |
| Qi Tang, Yanghai Zhang, Linxiu Yue, Hongying Ren, Chuanying Pa. Ssc-miR-429 expression proliles and functions on inducing Leydig cells apoptosis. Theriogenology. vol 216. 2023-12-29. PMID:38157808. |
in this study, we examined the expression of mir-429 in seven pig tissues (heart, liver, spleen, lung, kidney, testis, epididymis, brain) and investigated its impact on the proliferation and apoptosis of testicular interstitial cells using various techniques such as cck-8, edu, tunel, western blot, among others. |
2023-12-29 |
2024-01-05 |
Not clear |
| Xiaomei Zhang, Jian Wang, Haiying L. RTKN2 knockdown alleviates the malignancy of breast cancer cells by regulating the Wnt/β-catenin pathway. Scientific reports. vol 13. issue 1. 2023-12-28. PMID:38155217. |
fcm and western blot assay were performed to measure the function of rtkn2 silencing on bc cell apoptosis. |
2023-12-28 |
2023-12-31 |
Not clear |
| Dan Cui, Zexi Li, Chao Wei, Qianjin Zhang, Can Xia. Long non-coding RNA LINC00491 accelerates head and neck squamous cell carcinoma progression through regulating miR-508-3p/SATB1 axis and activating Wnt signaling pathway. Cytokine. vol 175. 2023-12-27. PMID:38150791. |
functionally, we carried out a series of assays to measure cell proliferation, apoptosis, migration and invasion, such as edu assay, colony formation, wound healing and western blot assays. |
2023-12-27 |
2023-12-30 |
Not clear |
| Lihong Zhang, Qingzi Guo, Ran An, Shuhan Shen, Lin Yi. In vitro ischemic preconditioning mediates the Ca Brain research. 2023-12-23. PMID:38141801. |
cell viability was detected by mtt, apoptosis by hoechst 33,258 staining, the levels of tnf-α and il-1β mrna by rt-qpcr and elisa, and the levels of can, nfat, cox-2 by rt-qpcr and western blot. |
2023-12-23 |
2023-12-25 |
Not clear |
| Mine Caglayan, Sibel Ozde. Potential impacts of bisphenols on prostate cells: An overview of cytotoxicity, proliferation, oxidative stress, apoptosis, and ER-stress response activation. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 2023-12-22. PMID:38134982. |
pnt1a and pc-3 were treated with bpa, bpf and bps at concentrations of 0.1, 1 and 10 μm for 48 h cytotoxicity, brdu cell proliferation, ros generation, apoptosis detection, gene expression analysis and western blot analysis were performed. |
2023-12-22 |
2023-12-25 |
human |
| Ling-Ray Tai, Yi-Fen Chiang, Ko-Chieh Huang, Hsin-Yuan Chen, Mohamed Ali, Shih-Min Hsi. Hinokitiol as a modulator of TLR4 signaling and apoptotic pathways in atopic dermatitis. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 170. 2023-12-21. PMID:38128179. |
additionally, the cell culture model enabled the evaluation of apoptosis and ros levels using mtt assay, crystal violet staining, western blot, and dcfda assays. |
2023-12-21 |
2023-12-24 |
Not clear |
| Gao Yuan, Ning Li, Xue Qing, Wu Lujia, Huang Kai, Xu Xiangyang, Yuan Ye, Li Qin, Liu Xiaohong, Han Li. BFGF attenuates aortic valvular interstitial cell calcification by inhibiting endoplasmic reticulum stress-mediated apoptosis. Experimental cell research. 2023-12-19. PMID:38113969. |
the protein expression level was detected by western blot, and apoptosis was determined by flow cytometry. |
2023-12-19 |
2023-12-23 |
rat |
| Ting-Ting Li, Jie Chen, En-Sheng Ji, Ya-Jing Gu. [Effect and mechanism of Danggui Buxue Decoction-containing serum in mitigating H9c2 cell injury caused by exposure to intermittent low oxygen]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 21. 2023-12-19. PMID:38114184. |
western blot was employed to determine the expression levels of the autophagy-related proteins microtubule-associated proteins light chain 3Ⅱ(lc3Ⅱ), microtubule-associated proteins light chain 3Ⅰ(lc3Ⅰ), p62, parkin and apoptosis related proteins pro caspase-3, caspase-3, b-cell lymphoma-2(bcl-2), bcl-2-associated x(bax). |
2023-12-19 |
2023-12-23 |
Not clear |
| Xinru Yang, Jian Liang, Yue Shu, Linlin Wei, Cailing Wen, Hui Luo, Liqing Ma, Tian Qin, Bin Wang, Siyu Zeng, Ying Liu, Chun Zho. Asperosaponin VI facilitates the regeneration of skeletal muscle injury by suppressing GSK-3β-mediated cell apoptosis. Journal of cellular biochemistry. 2023-12-11. PMID:38079224. |
apoptosis and autophagy-related protein expression were evaluated t s by western blot, and muscle regeneration markers were quantified by quantitative polymerase chain reaction. |
2023-12-11 |
2023-12-17 |
mouse |
| Ramadan F Abdelaziz, Ahmed M Hussein, Mohamed H Kotob, Christina Weiss, Krzysztof Chelminski, Tamara Stojanovic, Christian R Studenik, Mohammed Auf. Enhancement of Radiation Sensitivity by Cathepsin L Suppression in Colon Carcinoma Cells. International journal of molecular sciences. vol 24. issue 23. 2023-12-09. PMID:38069428. |
in addition, the study conducted protein expression analysis by western blot and immunofluorescence assay, cytotoxicity mtt, and apoptosis assays. |
2023-12-09 |
2023-12-17 |
Not clear |
| Zhifang Tang, Jingyuan Li, Chuan L. Post-Transcriptional Regulator RBM47 Stabilizes FBXO2 mRNA to Advance Osteoarthritis Development: WGCNA Analysis and Experimental Validation. Biochemical genetics. 2023-12-09. PMID:38070024. |
functional analysis results from the mtt assay, flow cytometry, evaluation of ldh activities and inflammatory mediators, and western blot analysis of extracellular matrix (ecm) proteins, showed that rbm47 knockdown significantly alleviated inflammation, apoptosis, and ecm degradation in interleukin 1β (il-1β)-treated chondrocytes. |
2023-12-09 |
2023-12-17 |
Not clear |
| Yiting Hou, Lihua Dong, Lihua Ca. Saxagliptin reduces the injury of Alzheimer's disease cell model by down-regulating the expression of miR-483-5p. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 12. 2023-12-08. PMID:38063096. |
then the levels of mda, sod and gsh-px in each group were detected by elisa method; cell apoptosis was detected by flow cytometry; the protein expression levels of bax and bcl-2 were detected by western blot; the expression level of mir-483-5p was detected by rt-qpcr. |
2023-12-08 |
2023-12-17 |
Not clear |
| Daomin Lu, Yuzheng Yang, Wukai Ma, Xueming Yao, Yi Ling, Ying Huang, Qiuyi Wang, Chengyu Xia, Lei Ho. Stigmasterol Depresses the Proliferation and Facilitates the Apoptosis of Fibroblast-Like Synoviocytes via the PI3K/AKT Signaling Pathway in Collagen-Induced Arthritis Rats. Alternative therapies in health and medicine. 2023-12-08. PMID:38064612. |
in addition, we investigated the mechanism of stigmasterol inhibiting fls proliferation and promoting its apoptosis by qpcr, western blot, and immunofluorescence assays. |
2023-12-08 |
2023-12-17 |
rat |
| Xixi Li, Zhipeng Huang, Hua Chao, Xunxun Li. The mechanism of Semen Persicae-Flos Carthami in treating hypertrophic scar: A study based on network pharmacological analysis and in vitro experiments. Chemical biology & drug design. 2023-12-06. PMID:38056934. |
besides, a modified explant culture method was applied to separate primary hypertrophic scar fibroblasts (hsfs); mtt assay to detect cell viability of hsfs after treatment by sp-fc for 24 h; annexin v-fitc/pi double staining combined with flow cytometry to test apoptosis; western blot to check the protein expression level of p53; and real-time fluorescence quantitative pcr to determine mrna level of p53. |
2023-12-06 |
2023-12-10 |
Not clear |
| Yun Chen, Bocheng Zhang, Cui Zhong, Yuqing Zhou, Lei Xue, Chenhui Luo, Liang Yi, Qian Gong, Ying Lon. let-7g sensitized liver cancer cells to 5-fluorouracil by downregulating ABCC10 expression. Chemical biology & drug design. 2023-12-06. PMID:38054583. |
the levels of biomarkers related to cell cycle progression and apoptosis were detected by western blot assays. |
2023-12-06 |
2023-12-10 |
mouse |