| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Qiong Duan, Ruochen Li, Mingxiao Wang, Zhenting Cui, Xia Zhu, Fanghong Chen, Feng Han, Jianxin M. Exploring the anti-NSCLC mechanism of phillyrin targeting inhibition of the HSP90-AKT pathway. Naunyn-Schmiedeberg's archives of pharmacology. 2024-10-02. PMID:39356318. |
cck-8 assay, wound healing assay, apoptosis assay, western blot, and in vivo experiments verified the inhibitory effect of phn on nsclc. |
2024-10-02 |
2024-10-04 |
Not clear |
| Qian Yang, Qi-Ming Zhong, Mei-Qing Song, Li-Guo Tong, Chong-Zhi Ba. Exosomes derived from Danshen decoction-pretreated bone marrow mesenchymal stem cells alleviate myocardial infarction via anti-apoptosis and up-regulation of autophagy. Heliyon. vol 10. issue 18. 2024-09-30. PMID:39347388. |
on the 7th, 14th and 28th days, serum ck, ldh, α-hbdh, alt, and ast were measured and electrocardiogram changes were monitored to identify cardiac function; triphenyltetrazolium chloride staining, hematein&eosin staining, masson trichrome staining and transmission electron microscope were adopted to analyze infarct area, cardiac morphology, histopathology, and fibrosis and cardiomyocyte ultrastructure; tunel assay, real-time pcr and western blot were performed to detect cardiomyocyte apoptosis and autophagy. |
2024-09-30 |
2024-10-02 |
rat |
| Li Qiu, Zhaoming Huan. Downregulation of IGFBP7 Alleviates LPS-induced Inflammation and Apoptosis in WI-38 Cells via Enhancing Mitophagy. Cell biochemistry and biophysics. 2024-09-30. PMID:39347911. |
next, igfbp7 interference plasmid was constructed, and cell viability and apoptosis were detected by cck8, flow cytometry and western blot. |
2024-09-30 |
2024-10-02 |
human |
| Yafei Zhu, Xinlin Zhao, Tibenda Jonnea Japhet, Jun Chen, Qipeng Zha. Sampling of N-methyl-N-nitrosourea-induced Rat's Retina Damage and Multi-index Evaluation of Pathological Changes. Journal of visualized experiments : JoVE. issue 211. 2024-09-30. PMID:39345110. |
additionally, we performed hematoxylin-eosin staining to assess retinal pathological changes. determination of the apoptosis rate and apoptosis protein by tunel and western blot. |
2024-09-30 |
2024-10-02 |
rat |
| Selman Gencer, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Nurhan Akaras, Hasan Şimşek, Fatih M Kandemi. The ameliorative effect of carvacrol on sodium arsenite-induced hepatotoxicity in rats: Possible role of Nrf2/HO-1, RAGE/NLRP3, Bax/Bcl-2/Caspase-3, and Beclin-1 pathways. Journal of biochemical and molecular toxicology. vol 38. issue 10. 2024-09-25. PMID:39318027. |
oxidative stress, inflammation, apoptosis, autophagy damage pathways parameters, and liver tissue integrity were analyzed using biochemical, molecular, western blot, histological, and immunohistological methods. |
2024-09-25 |
2024-09-27 |
rat |
| Nan Jiang, Jiawei Kang, Yi Ding, Munire Shataer, Liangying Ma, Tayier Tuerson. MiR-509-3p promotes gastric cancer development by activating FOXM1-mediated p38/MK2 pathway. Biomolecules & biomedicine. 2024-09-25. PMID:39319839. |
cck-8, edu, transwell, wound healing assays, flow cytometry, and western blot analysis were employed to examine changes in proliferation, migration, invasion, apoptosis, foxm1, and the p38 mapk (p38)/mapk-activated protein kinase 2 (mk2) pathway in gc cells (mnk-45 and hgc-27) after mir-509-3p overexpression or knockdown, foxm1 overexpression, and application of the p38 pathway agonist anisomycin. |
2024-09-25 |
2024-09-27 |
Not clear |
| Yaping Xu, Chundong Yu, Hongbin Zhang, Tao Wang, Yujian Liu, Lupeng Wu, Shuping Zhong, Zaifa Hon. Downregulation of Brf1 Induces Liver Failure and Inhibits Hepatocellular Carcinoma Progression by Promoting Apoptosis. Journal of Cancer. vol 15. issue 17. 2024-09-24. PMID:39308682. |
western blot (wb) analysis, flow cytometry, and tunel assays were used to detect apoptosis. |
2024-09-24 |
2024-09-26 |
mouse |
| Xiangjun Yi, Xuan Chen, Zhenbin L. miR-200c targeting GLI3 inhibits cell proliferation and promotes apoptosis in non-small cell lung cancer cells. Medicine. vol 103. issue 38. 2024-09-23. PMID:39312343. |
the cell viability rate was detected by cell counting kit-8, cell invasion ability was detected with transwell, cell apoptosis and cell cycle was determined by flow cytometry, and the expression of gli3 was detected using quantitative polymerase chain reaction and western blot, to verify the effect of the interaction between mir-200c-3p and gli3 on the cell activities. |
2024-09-23 |
2024-09-26 |
Not clear |
| Marta Henklewska, Aleksandra Pawlak, Bożena Obmińska-Mrukowic. Targeting ATR Kinase as a Strategy for Canine Lymphoma and Leukaemia Treatment. Veterinary and comparative oncology. 2024-09-20. PMID:39300906. |
further, we estimated the level of apoptosis in berzosertib-treated cells via flow cytometry and assessed h2ax phosphorylation as a marker of dna damage using western blot technique. |
2024-09-20 |
2024-09-22 |
human |
| Feng Hu, Senbo Yan, Li Lin, Xiaoxia Qiu, Xinghe Lin, Weiwei Wan. Sacubitril/valsartan attenuated myocardial inflammation, fibrosis, apoptosis and promoted autophagy in doxorubicin-induced cardiotoxicity mice via regulating the AMPKα-mTORC1 signaling pathway. Molecular and cellular biochemistry. 2024-09-20. PMID:39304614. |
a variety of techniques were used to investigate cardiac inflammation, fibrosis, apoptosis, and autophagy, including western blot, real-time quantitative pcr (rt-qpcr), immunohistochemistry, and fluorescence. |
2024-09-20 |
2024-09-23 |
mouse |
| Menglan Liu, Zuoxiao Li, Zhiyu Lv, Yang Xi. Discussion of spinal cord neurons apoptosis and neuroprotection mechanism of NGF gene transfection mediated by recombinant adenovirus in EAE mice. Scientific reports. vol 14. issue 1. 2024-09-17. PMID:39289437. |
aqthe tunel method was employed to observe spinal neuron apoptosis in each group of mice; protein immunoblotting (western blot) and rt-pcr were used to measure ngf levels in the spinal cord tissues of each group, and western blotting was used to assess levels of cleaved caspase-3, bax, and bcl-2. |
2024-09-17 |
2024-09-20 |
mouse |
| Surya P Singh, Gopal Pathuri, Adam S Asch, Chinthalapally V Rao, Venkateshwar Madk. Stat3 Inhibitors TTI-101 and SH5-07 Suppress Bladder Cancer Cell Survival in 3D Tumor Models. Cells. vol 13. issue 17. 2024-09-14. PMID:39273033. |
western blot analysis was performed to evaluate the pharmacodynamic markers involved in cell proliferation, apoptosis, cancer stem cells (cscs), and stat3 signaling in bca. |
2024-09-14 |
2024-09-16 |
mouse |
| Feng-Xia Qu, Xiao Guo, Xiao-Jun Liu, Shu-Wen Zhang, Yue Xin, Jing-Yuan Li, Rong Wang, Chen-Ji Xu, Hai-Ying Li, Chang-Hong L. Treatment with a combination of myricitrin and exercise alleviates myocardial infarction in rats via suppressing Nrf2/HO-1 antioxidant pathway. Archives of biochemistry and biophysics. 2024-09-13. PMID:39271097. |
changes in reactive oxygen species (ros) levels, mitochondrial membrane potential (ΔΨm), apoptosis and nrf2/ho-1 pathway were analyzed by ros kit, jc-1 kit, tunel assay, western blot and immunohistochemistry. |
2024-09-13 |
2024-09-16 |
rat |
| Gengshui Zhao, Yongqi Fu, Chao Yang, Xuehui Yang, Xiaoxiao H. Identification and Validation of Endoplasmic Reticulum Stress-Related Gene in Traumatic Brain Injury. Journal of molecular neuroscience : MN. vol 74. issue 3. 2024-09-12. PMID:39264510. |
western blot suggested tbhq pretreatment could diminish ers and reduce the protein expressions of apoptosis in the primary cultured neuron injury model. |
2024-09-12 |
2024-09-14 |
Not clear |
| Palati Tuerxun, Takkun Ng, Jiadong Sun, Farong Ou, Xiaoshi Jia, Ke Zhao, Ping Zh. Lipoxin A4 modulates the PKA/CREB and NF-κB signaling pathway to mitigate chondrocyte catabolism and apoptosis in temporomandibular joint osteoarthritis. Experimental cell research. 2024-09-11. PMID:39260675. |
the viability of chondrocytes treated with lxa4 was evaluated with the cell counting kit-8 (cck-8) assay, while protein levels were assessed by western blot analysis, and the apoptosis rate was evaluated with terminal deoxynucleotidyl transferase (tdt)-mediated dutp nick-end labelling (tunel) staining. |
2024-09-11 |
2024-09-14 |
rat |
| Zeynep Akgun, Eda Dogan, Cumali Degirmenci, Ozlem Ozkaya Akagunduz, Mustafa Esassolak, Vildan Bozok, Melis Palama. Evaluation of the Effects of Vitamin D Analogs, Bevacizumab, and Radiotherapy in Uveal Melanoma Cells. Experimental eye research. 2024-09-11. PMID:39260786. |
annexin v/pi staining and western blot analyses for caspase-3, -8, and -9 were performed to analyze apoptosis. |
2024-09-11 |
2024-09-14 |
Not clear |
| Chun-Wen Lan, Hsin-Hung Chen, Jim Jinn-Chyuan She. Deoxyelephantopin induces apoptosis and cell cycle arrest in GL261 glioblastoma cells. Naunyn-Schmiedeberg's archives of pharmacology. 2024-09-10. PMID:39254878. |
western blot analysis examined apoptosis and cell cycle-related proteins. |
2024-09-10 |
2024-09-13 |
mouse |
| Yongya Zhang, Fei Wu, Sibei Guo, Ruijie Yin, Min Yuan, Xue Li, Xueru Zhao, Xiaohua L. Critical role of apoptosis in MeCP2-mediated epithelial-mesenchymal transition of ARPE-19 cells. Journal of cellular physiology. 2024-09-06. PMID:39238182. |
western blot analysis, quantitative reverse transcriptase-polymerase chain reaction (qrt-pcr), and immunofluorescence analysis were conducted to measure the protein levels associated with apoptosis, cell cycle and emt. |
2024-09-06 |
2024-09-08 |
human |
| Fa-Lin Wang, Xiaoxia Chang, Yuanyang Shi, Tingting Yang, Juan Li, Hongwei Dong, Qi Wang, Shujun Zhang, Jiaren Li. β-Ionone enhances the inhibitory effects of 5-fluorouracil on the proliferation of gastric adenocarcinoma cells by the GSK-3β signaling pathway. PloS one. vol 19. issue 9. 2024-09-06. PMID:39241034. |
the effects of bi and 5-fu alone or their combination on the cell viability, apoptosis, and mitochondrial membrane potential, the cell cycle, and its related proteins-cyclin d1, and cdk4 as well as pcna and gsk-3β were evaluated in sgc-7901 cells and mkn45 cells by mtt, mb, flow cytometry and western blot. |
2024-09-06 |
2024-09-09 |
mouse |
| Kaiping Zhang, Xiang Fang, Ye Zhang, Yin Zhang, Min Cha. Transcriptional activation of PINK1 by MyoD1 mediates mitochondrial homeostasis to induce renal calcification in pediatric nephrolithiasis. Cell death discovery. vol 10. issue 1. 2024-09-06. PMID:39242558. |
apoptosis-related proteins were evaluated using western blot analysis, and cell apoptosis was measured using flow cytometry. |
2024-09-06 |
2024-09-10 |
rat |