| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Nazım Abdülkadir Kankılıç, Hasan Şimşek, Nurhan Akaras, Cihan Gür, Mustafa İleritürk, Sefa Küçükler, Serkan A Akarsu, Fatih M Kandemi. Protective effects of naringin on colistin-induced damage in rat testicular tissue: Modulating the levels of Nrf-2/HO-1, AKT-2/FOXO1A, Bax/Bcl2/Caspase-3, and Beclin-1/LC3A/LC3B signaling pathways. Journal of biochemical and molecular toxicology. vol 38. issue 2. 2024-02-13. PMID:38348713. |
the parameters of oxidative stress, inflammation, apoptosis, and autophagic damage were evaluated by using biochemical, molecular, western blot, and histological methods in testicular issues. |
2024-02-13 |
2024-02-15 |
rat |
| Ying Gao, Weijie Tao, Shoujun Wang, Ran Duan, Zhendong Zhan. AKR1C3 silencing inhibits autophagy-dependent glycolysis in thyroid cancer cells by inactivating ERK signaling. Drug development research. vol 85. issue 1. 2024-02-13. PMID:38349266. |
additionally, the expression of proteins related to cell cycle, apoptosis, glycolysis, autophagy, and extracellular signal-regulated kinase (erk) signaling in cells and tumor tissues was assessed by western blot. |
2024-02-13 |
2024-02-15 |
mouse |
| Qiao-Hui Liu, Ke Zhang, Shu-Shu Feng, Li-Juan Zhang, Shun-Ying Li, Hang-Yu Wang, Jin-Hui Wan. Rosavin Alleviates LPS-Induced Acute Lung Injure by Modulating the TLR-4/NF-κB/MAPK Singnaling Pathways. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38339153. |
transcriptomics analysis and western blot assays were utilized to verify the molecular mechanism, rosavin (20, 40, and 80 mg/kg) dose-dependently ameliorated histopathological alterations, reduced the levels of inflammatory factors, and inhibited the tlr-4/nf-κb/mapk signaling pathway and apoptosis activation. |
2024-02-10 |
2024-02-12 |
mouse |
| Jifang Liang, Junkun Zhang, Jixiu Fan, Shuxian Chen, Weidong W. ANXA3 interference inactivates ERK/ELK1 pathway to mitigate inflammation and apoptosis in sepsis-associated acute lung injury. Molecular immunology. vol 167. 2024-02-04. PMID:38310670. |
western blot analyzed the expression of proteins associated with inflammation, apoptosis and extracellular-signal-regulated kinase (erk)/ets-like gene 1 (elk1) signaling. |
2024-02-04 |
2024-02-07 |
mouse |
| Feng Hu, Chaoyang Li. TRPM2 knockdown attenuates myocardial apoptosis and promotes autophagy in HFD/STZ-induced diabetic mice via regulating the MEK/ERK and mTORC1 signaling pathway. Molecular and cellular biochemistry. 2024-02-02. PMID:38308007. |
western blot, real-time quantitative pcr (rt-qpcr), immunohistochemistry and fluorescence, electron, cck-8, and flow cytometry were used to evaluate the phenotype of cardiac inflammation, fibrosis, apoptosis, and autophagy. |
2024-02-02 |
2024-02-05 |
mouse |
| Yuzhou Xue, Yu Hu, Shikai Yu, Wenyan Zhu, Lin Liu, Minghao Luo, Suxin Luo, Jian Shen, Longxiang Huang, Jie Liu, Dingyi Lv, Wenming Zhang, Jingyu Wang, Xiang L. The lncRNA GAS5 upregulates ANXA2 to mediate the macrophage inflammatory response during atherosclerosis development. Heliyon. vol 10. issue 2. 2024-01-31. PMID:38293536. |
apoptosis and inflammatory markers in macrophages were detected by western blot. |
2024-01-31 |
2024-02-02 |
Not clear |
| Ting Liu, Congjie Zhai, Bo Tian, Chao Li, Shuangshuang Han, Shihui Wang, Mingda Xuan, Dehua Liu, Yunxia Zhao, Hongyan Zhao, Weifang Yu, Jia Wan. Downregulation of Roundabout guidance receptor 2 suppresses hepatocellular carcinoma progression by interacting with Y-box binding protein 1. Scientific reports. vol 14. issue 1. 2024-01-31. PMID:38297025. |
then we established hepg2 and huh7 hepatoma cell lines with knock-down robo2 by transfection with lentiviral vectors, and examined the occurrence of emt, proliferation and apoptosis abilities in hcc cells by western blot, flow cytometry, wound healing assay and tunel staining. |
2024-01-31 |
2024-02-03 |
human |
| Cian Zhang, Yongying Liu, Jing Zhao, Jingyu Xu, Bei Pei, Xuan Liu, Xiaoqiang Yu. KIAA0101 promotes cisplatin resistance through regulating cell apoptosis in lung cancer cells. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 14. 2024-01-27. PMID:38279448. |
western blot analysis was performed to measure the levels of p53-related apoptosis proteins. |
2024-01-27 |
2024-01-29 |
human |
| Yulin Zhang, Hongxian Wu, Chaozhi Xu, Shanqian Li, Yue Hu, Zongyi Zhang, Guixian Wu, Yuling Liu, Lin Yang, Yue Huang, Wenjun Lu, Lina H. (-)-Epigallocatechin gallate alleviates chronic unpredictable mild stress-induced depressive symptoms in mice by regulating the mTOR autophagy pathway and inhibiting NLRP3 inflammasome activation. Food science & nutrition. vol 12. issue 1. 2024-01-25. PMID:38268911. |
then, elisa, western blot and qt-pcr tests were used to assess the expression of the key components of the nlrp3 inflammasome and its downstream inflammatory effectors (e.g., il-1β, il-18), autophagy markers (beclin-1, lc3, p62) and apoptosis markers (bax, bcl-2) in mouse brain tissues. |
2024-01-25 |
2024-01-27 |
mouse |
| Yue Wu, Dan Chen, Longguang L. EXPRESS: Morinda officinalis polysaccharide promotes the osteogenic differentiation of human bone marrow-derived mesenchymal stem cells via microRNA-210-3p / scavenger receptor class A member 3. Journal of investigative medicine : the official publication of the American Federation for Clinical Research. 2024-01-24. PMID:38264863. |
cell counting kit-8 assay was employed to detect cell viability; terminal-deoxynucleoitidyl transferase mediated nick end labeling assay and flow cytometry were adopted to detect apoptosis; alkaline phosphatase (alp) activity assay kit was applied to detect alp activity; western blot was executed to quantify the expression levels of scara3, osteogenic and adipogenic differentiation markers. |
2024-01-24 |
2024-01-26 |
human |
| Peipei Wang, Shitong Min, Congliang Chen, Junmei Hu, Dapeng Wei, Xia Wan. Phytohemagglutinin from Phaseolus vulgaris enhances the lung cancer cell chemotherapy sensitivity by changing cell membrane permeability. Journal of natural medicines. 2024-01-24. PMID:38265611. |
our results demonstrated that the pha significantly enhanced the sensitivity of lung cancer cells to ddp and adm, and western blot showed that pha combined with ddp or adm enhance cytotoxic effects by inhibiting autophagy and promoting apoptosis. |
2024-01-24 |
2024-01-26 |
Not clear |
| XueFeng Feng, Lin Yang, Xiaojun Liu, Menghan Liu, Lu Liu, Jing Liu, JianMin Lu. Long non-coding RNA small nucleolar RNA host gene 29 drives chronic myeloid leukemia progression via microRNA-483-3p/Casitas B-lineage Lymphoma axis-mediated activation of the phosphoinositide 3-kinase/Akt pathway. Medical oncology (Northwood, London, England). vol 41. issue 2. 2024-01-22. PMID:38252204. |
western blot analysis was employed to assess protein expressions related to cellular proliferation, apoptosis, and oncogenesis. |
2024-01-22 |
2024-01-24 |
human |
| Chandramohan Kiruthiga, Devasahayam Jaya Balan, Nagaiah Hari Prasath, Muthushanmugam Manikandakrishnan, Sakthivel Jafni, Narayanasamy Marimuthu Prabhu, Shunmugiah Karutha Pandian, Kasi Pandima Dev. Synergistic induction of apoptosis in lung cancer cells through co-delivery of PLGA phytol/α-bisabolol nanoparticles. Naunyn-Schmiedeberg's archives of pharmacology. 2024-01-19. PMID:38240783. |
apoptosis was confirmed through annexin v-fitc/pi staining and western blot analysis, which also revealed changes in bax and bcl-2 protein expression. |
2024-01-19 |
2024-01-21 |
zebrafish |
| Chao Ma, Jizhi Zhao, Lian Zhou, Congwei Jia, Yanping Shi, Xing Li, Kedi Jihu, Tao Zhan. Targeting ENPP1 depletion may be a promising therapeutic strategy for treating oral squamous cell carcinoma via cytotoxic autophagy-related apoptosis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 38. issue 2. 2024-01-17. PMID:38231531. |
cellular key proteins related to cell autophagy and apoptosis were evaluated by western blot and immunofluorescent staining. |
2024-01-17 |
2024-01-19 |
mouse |
| Chongyun Wu, Qianting Deng, Ling Zhu, Timon Cheng-Yi Liu, Rui Duan, Luodan Yan. Methylene Blue Pretreatment Protects Against Repeated Neonatal Isoflurane Exposure-Induced Brain Injury and Memory Loss. Molecular neurobiology. 2024-01-17. PMID:38233687. |
immunofluorescence staining, f-jade c staining, tunel staining, and western blot analysis were performed to determine mitochondrial fragmentation, neuronal injury, degeneration, and apoptosis. |
2024-01-17 |
2024-01-20 |
rat |
| Lin Bai, Yaping Zhang, Changmin Zheng, Shifu Xu, Yining He, Guangqiang Yu, Delun Huang, Yulin Huang, Mingxing Li, Changlong X. Tanshinone IIA protects mouse testes from heat stress injury by inhibiting apoptosis and TGFβ1/Smad2/Smad3 signaling pathway. Cell stress & chaperones. vol 28. issue 6. 2024-01-15. PMID:38225017. |
using western blot technology, we found that the hs group upregulated tgfβ1/smad2/smad3 pathway protein expression, causing cell apoptosis, testicular tissue organic lesions, and affecting testicular secretion function. |
2024-01-15 |
2024-01-18 |
mouse |
| Junjie Zhang, Bin M. Alpinetin alleviates LPS-induced lung epithelial cell injury by inhibiting p38 and ERK1/2 signaling via aquaporin-1. Tissue & cell. vol 87. 2024-01-13. PMID:38217934. |
cell activity together with apoptosis was judged employing cell counting kit-8 (cck-8), flow cytometry along with western blot. |
2024-01-13 |
2024-01-16 |
Not clear |
| Cagri Cakici, Benay Daylan, Ruveyde Safiye Unluer, Ebru Emekli-Alturfan, Sule Ayla, Hilal Eren Gozel, Pakize Yigit, Elif Yavuz Dokgoz, Turkan Yigitbas. LDH-A Inhibitor as a Remedy to Potentiate the Anticancer Effect of Docetaxel in Prostate Cancer. Journal of Cancer. vol 15. issue 3. 2024-01-12. PMID:38213726. |
from the tumor tissue samples, apoptosis analysis was performed using tunel staining, and emt was investigated using western blot and qpcr. |
2024-01-12 |
2024-01-14 |
mouse |
| Lei Ma, Ke Huang, Haibo Zhang, Eungyung Kim, Hyeonjin Kim, Zhibin Liu, Chae Yeon Kim, Kanghyun Park, Muhammad Atif Raza, Kirim Kim, Junkoo Yi, Yonghun Sung, Zae Young Ryoo, Yong-Gun Kim, Myoung Ok Ki. Imatinib inhibits oral squamous cell carcinoma by suppressing the PI3K/AKT/mTOR signaling pathway. Journal of Cancer. vol 15. issue 3. 2024-01-12. PMID:38213733. |
lastly, the effect of imatinib on oscc cell apoptosis was verified with flow cytometry, and its inhibitory mechanism was confirmed through western blot. |
2024-01-12 |
2024-01-14 |
Not clear |
| Min Huang, Junfeng Wang, Zhengrong Zhang, Xueliang Zu. ZMIZ1 Regulates Proliferation, Autophagy and Apoptosis of Colon Cancer Cells by Mediating Ubiquitin-Proteasome Degradation of SIRT1. Biochemical genetics. 2024-01-12. PMID:38214831. |
specific shrna transfection was used to knock down the expression of zmiz1 in colon cancer cell lines (hct116 and ht29), and cell proliferation was detected using edu and cck-8 reagents, apoptosis by flow cytometry, and autophagy by western blot. |
2024-01-12 |
2024-01-14 |
Not clear |