| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiyuan Hu, Hongdou Liu, Tiao Luo, Ling Chen, Ting Peng, Min Wen, Wensong Luo, Qunfang Xu, Yuanzhu Xie, Mo Li, Mingquan Liu, Xiaohe Liu, Suyou Liu, Shuaiwen Zhu, Zizheng Zou, Zhiyong Lu. Naphthoquinone-derived ZSW-4B induces apoptosis in triple-negative breast cancer via AMPK signalling activation. Scientific reports. vol 14. issue 1. 2024-11-18. PMID:39558000. |
flow cytometry and western blot analysis revealed that zsw-4b induces apoptosis in tnbc cells. |
2024-11-18 |
2024-11-22 |
mouse |
| Cheng Wang, Ping Wang, Jialei Fu, Zongtong Yang, Haitao Du, Mengru Zhang, Shuyu Zhang, Mingyue Shen, Tingting Wang, Kai Wei, Ruiliang Zh. Pinus massoniana pollen polysaccharides alleviate LPS-induced myocardial injury through p110β-mediated inhibition of the PI3K/AKT/NFκB pathway. International journal of biological macromolecules. 2024-11-17. PMID:39551317. |
in this study, we aimed to investigate the impact of ppps on smi, myocardial enzyme levels, pathological changes, oxidative stress, cell apoptosis, and related signaling pathways in lps-induced smi models were observed by hematoxylin-eosin (he) staining, immunohistochemical (ihc) staining, qpcr, western blot analysis, with a particular focus on anti-inflammatory effects of ppps. |
2024-11-17 |
2024-11-22 |
Not clear |
| Yanxue Zhu, Xingzhi Lv, Ruifang Li, Zihan Gao, Chanhao Lei, Lan Wang, Sanqiang L. Saikosaponin-b2 Regulates the Proliferation and Apoptosis of Liver Cancer Cells by Targeting the MACC1/c-Met/Akt Signalling Pathway. Advances in pharmacological and pharmaceutical sciences. vol 2024. 2024-11-15. PMID:39544485. |
meanwhile, annexin v-fitc/pi staining and western blot analysis of cleaved caspase 9 and cleaved caspase 3 demonstrated that ss-b2 induced apoptosis of hepg2 liver cancer cells. |
2024-11-15 |
2024-11-17 |
mouse |
| Zhao Li, Ya-Hong Wu, Ye-Qing Guo, Xiao-Jia Min, Ying Li. Tasquinimod promotes the sensitivity of ovarian cancer cells to cisplatin by down-regulating the HDAC4/p21 pathway. The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology. 2024-11-14. PMID:39539173. |
rt-pcr and western blot analyses, flow cytometry, cck8 assay, and immunofluorescence were utilized to investigate the effects of tasquinimod on gene expression, cell cycle, apoptosis, viability, and protein levels in oc cells. |
2024-11-14 |
2024-11-17 |
mouse |
| Ning Tang, Nuojin Geng, Xinhua Zh. Evaluation of Xihuang Pill in inducing pyroptosis in glioma cells through modulation of miR-21-5p. 3 Biotech. vol 14. issue 12. 2024-11-14. PMID:39529806. |
cell viability was measured using the cck-8 assay, apoptosis was detected by flow cytometry, and expression levels of p-stat3/stat3 and pyroptosis-related proteins were determined by western blot. |
2024-11-14 |
2024-11-17 |
human |
| Kebei Xie, Yanli Wang, Zimin Che. Mechanism of the combined action of green tea polyphenols and concurrent radiochemotherapy in regulating GSK-3β to treat non-small cell lung cancer through the Wnt∕β-catenin pathway. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 65. issue 3. 2024-11-12. PMID:39529343. |
the cell viability was assessed using the cell counting kit-8 (cck-8) assay, proliferation was examined through the colony formation assay, apoptosis was monitored via flow cytometry, cell migration, and epithelial-mesenchymal transition (emt)-associated proteins (e-cadherin, n-cadherin) were determined by western blot. |
2024-11-12 |
2024-11-17 |
human |
| Xingli Tan, Xiaoli Su, Ying Wang, Weiwei Liang, Di Wang, Di Huo, Hongyong Wang, Yan Qi, Wenmo Zhang, Ling Han, Dongmei Zhang, Ming Wang, Jing Xu, Honglin Fen. BRD7 regulates cellular senescence and apoptosis in ALS by modulating p21 expression and p53 mitochondrial translocation respectively. Neuroscience. vol 563. 2024-11-10. PMID:39510439. |
we analyzed rna levels using qrt-pcr, protein levels through immunofluorescence and western blot, and apoptosis via tunel staining. |
2024-11-10 |
2024-11-16 |
Not clear |
| Wenbo Shi, Tongyangzi Zhang, Li Zhang, Wanzhen Li, Zhiwei Chen, Xianghuai X. MLLT3 knockdown suppresses proliferation and cell mobility in human lung adenocarcinoma. Drug development research. vol 85. issue 7. 2024-11-06. PMID:39503060. |
specific markers of apoptosis, cell cycle, epithelial-mesenchymal transition (emt), and mllt3-induced signaling were examined by western blot. |
2024-11-06 |
2024-11-08 |
human |
| Alok Kumar Pandey, Vishal Trived. Heat shock protein HSPA8 impedes hemin-induced cellular-toxicity in liver. Toxicology in vitro : an international journal published in association with BIBRA. 2024-11-01. PMID:39486598. |
western blot analysis revealed that hemin triggers both the extrinsic and intrinsic pathways of apoptosis in hepg2 cells. |
2024-11-01 |
2024-11-05 |
Not clear |
| Stuti Biswal, Munmun Panda, Bijesh Kumar Biswa. Shikonin Stimulates Mitochondria-Mediated Apoptosis by Enhancing Intracellular Reactive Oxygen Species Production and DNA Damage in Oral Cancer Cells. Journal of cellular biochemistry. 2024-11-01. PMID:39485022. |
we investigated the antiproliferative, antimigratory, cell cycle arresting and apoptosis promoting activity of shk in oral cancer cells by performing mtt and morphological assay, colony, and tumor sphere formation assay, ao/etbr and dapi staining, annexin v-fitc/pi staining, assay for reactive oxygen species (ros) and mitochondrial membrane potential (mmp) measurement, comet assay, qrt-pcr, and western blot analysis. |
2024-11-01 |
2024-11-03 |
Not clear |
| Rongchen Zhu, Xuewen Tong, Yuhan Du, Jiahua Liu, Xuefei Xu, Yang He, Liankui Wen, Zhitong Wan. Improvement of chlorpyrifos-induced cognitive impairment by mountain grape anthocyanins based on PI3K/Akt signaling pathway. Pesticide biochemistry and physiology. vol 205. 2024-10-30. PMID:39477625. |
morris water maze, histopathological, elisa and western blot analyses showed that anthocyanins effectively ameliorated cpf-induced spatial learning memory impairment in mice by ameliorating cpf-induced ache inhibition, oxidative stress, and neuroinflammation and by modulating the levels of apoptosis (caspase-3, caspase-9) and autophagy (lc3ii/ lc3i, beclin1, p62, mtor) biomarkers, in order to restore damaged hippocampal tissue morphology, neuron and synapse structures. |
2024-10-30 |
2024-11-02 |
mouse |
| Meng Lou, Lian Zou, Liying Zhang, Yongquan Lu, Jia Chen, Beige Zon. MECOM and the PRDM gene family in uterine endometrial cancer: bioinformatics and experimental insights into pathogenesis and therapeutic potentials. Molecular medicine (Cambridge, Mass.). vol 30. issue 1. 2024-10-29. PMID:39468462. |
techniques included crispr-cas9 for gene editing and various cellular assays (cck-8, flow cytometry, transwell) to evaluate the effects of mecom on cell proliferation, migration, and apoptosis, alongside western blot analysis for protein regulation in the tgf-beta pathway. |
2024-10-29 |
2024-10-31 |
Not clear |
| Bader Huwaimel, Kareem M Younes, Amr S Abouzied, Akram M Elkashlan, Fawaz N Alheibshy, Ahmed Alobaida, Abdullah Turki, Saleh A Alquwaiay, Naif Alqahatani, Sulaiman A Alsuwayag. Phytochemical composition, in vitro cytotoxicity, and in silico docking properties of Tamarix tetragyna L. Scientific reports. vol 14. issue 1. 2024-10-27. PMID:39462121. |
in addition, in vitro cytoxicity activity versus cancer cell lines such mcf-7, hepg-2, hct-116, and a-549 was examined by mtt assay method, together with exploring its apoptosis effect by flow cytometry and western blot analysis techniques. |
2024-10-27 |
2024-10-29 |
Not clear |
| Xiaojing Hua, Qing Lu, Li Zen. SESN2 Ameliorates Dihydrotestosterone-induced Human Ovarian Granulosa Cell Damage by Activating AMPK/ULK1-mediated Mitophagy. Cell biochemistry and biophysics. 2024-10-17. PMID:39417977. |
the expression of sesn2, cell apoptosis, oxidative stress, mitophagy and ampk/ulk1 signaling-related proteins were measured by western blot. |
2024-10-17 |
2024-10-19 |
human |
| Wei-Yu Lin, Yu-Hsuan Cheng, Pei-Yu Liu, Shih-Ping Hsu, San-Chi Lin, Chiang-Ting Chie. Carvedilol through ß1-Adrenoceptor blockade ameliorates glomerulonephritis via inhibition of oxidative stress, apoptosis, autophagy, ferroptosis, endoplasmic reticulum stress and inflammation. Biochemical pharmacology. 2024-10-14. PMID:39401703. |
we examined rana and rena response to anti-thy1.1 and compared the effect of dnx or dnax on urinary oxidative stress, renal gp91, tyrosine hydroxylase (th), calcitonin gene-related peptide (cgrp), apoptosis, autophagy, ferroptosis, antioxidant enzymes, endoplasmic reticulum (er) stress and inflammation by western blot. |
2024-10-14 |
2024-10-17 |
rat |
| Mona Khoshbakht, Mohammad Mahdi Forghanifard, Hossein Aghamollaei, Jafar Aman. In silico and in vitro evaluation of a PE38 and Nb-based recombinant immunotoxin targeting the GRP78 receptor in cancer cells. Biotechnology and applied biochemistry. 2024-10-13. PMID:39397264. |
accordingly, the cytotoxicity, binding affinity, cell internalization, and apoptosis were evaluated using mtt, enzyme-linked immunosorbent assay, and western blot. |
2024-10-13 |
2024-10-16 |
Not clear |
| Sepideh Goudarzi, Razieh Mohammad Jafari, Nikou Farsiu, Behnam Amini, Mohammad Amin Manavi, Javad Fahanik-Babaei, Shahram Ejtemaei-Mehr, Ahmad Reza Dehpou. Protective Effects of Licofelone on Scopolamine-Induced Spatial Learning and Memory Impairment by Enhancing Parkin-Dependent Mitophagy and Promotion of Neural Regeneration and in Adult Mice. European journal of pharmacology. 2024-10-12. PMID:39395583. |
hippocampi were used to evaluate the levels of apoptosis via tunel assay, neural regeneration via immunohistochemistry method detecting doublecortin and nestin, and mitophagy via western blot of mitophagy proteins parkin and atg5. |
2024-10-12 |
2024-10-15 |
mouse |
| Bharathkumar Nagaraj, Arvind Sivasubramanian, Shazia Anjum Musthafa, Sadiq Muhammad, Aswathy Karanath Anilkumar, Ganesh Munuswamy-Ramanujam, Chinnaperumal Kamaraj, Sivaraman Dhanasekaran, Vetriselvan Subramaniya. Clerodane diterpene 3-deoxycaryoptinol (Clerodin) selectively induces apoptosis in human monocytic leukemia (THP-1) cells and upregulates apoptotic protein caspase-3. Free radical biology & medicine. 2024-10-11. PMID:39393554. |
moreover, the western blot was used to detect mitochondrial apoptosis of thp-1 cells. |
2024-10-11 |
2024-10-14 |
human |
| Beibei Qin, Dongfang Tang, Mingzhi Zhan. miR-149-3p targeting Biomolecules & biomedicine. 2024-10-10. PMID:39388706. |
western blot analysis was used to examine proteins related to migration, invasion, apoptosis, and tmprss4 expression. |
2024-10-10 |
2024-10-13 |
mouse |
| Jing Bai, Wen-Bo Sun, Wei-Chao Zheng, Xu-Peng Wang, Yang Ba. Carbon monoxide-releasing molecule-3 ameliorates traumatic brain injury-induced cardiac dysfunctions via inhibition of pyroptosis and apoptosis. Molecular and cellular biochemistry. 2024-10-08. PMID:39377871. |
24 h post-trauma, the cardiac function, pathological change, serum troponin t and creatine kinase-mb (ck-mb) levels, pyroptosis, apoptosis and expressions of tunel staining, gasdermin d (gsdmd), il-1β, il-18, ratio bax/bcl-2 were assessed by echocardiography, hematoxylin-eosin staining, chemiluminescence, immunofluorescence, and western blot assays, respectively. |
2024-10-08 |
2024-10-10 |
rat |