| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tingting Liu, Enhua Zhang, Shichao Cui, Haoyu Dai, Xiaohui Yang, Cunzhi Li. Effects of 630 nm laser on apoptosis, metastasis, invasion and epithelial-to-mesenchymal transition of human lung squamous cell carcinoma H520 cells mediated by hematoporphyrin derivatives. Lasers in medical science. vol 39. issue 1. 2024-08-30. PMID:39210165. |
cell proliferation was assessed using cck8 assay; cell apoptosis was detected by hoechst 33258 staining and flow cytometry; cell migration and invasion abilities were evaluated using wound-healing and invasion assays; and protein and mrna expressions were analyzed by western blot and reverse transcription-polymerase chain reaction (rt-pcr) respectively. |
2024-08-30 |
2024-09-04 |
human |
| Mei Feng, Xue Jing Wang, Yi Liu, Wei Zhang, Ying Wang, Chuchu Zhang, Shengchuan Ba. Transcriptomics Reveals the Mechanism of Platycodin D Targeting TGFβ for Anti-Lung Cancer Activity. Integrative cancer therapies. vol 23. 2024-08-27. PMID:39189615. |
subsequently, we used immunofluorescent labeling of ki-67 to evaluate cell proliferation, flow cytometry to assess apoptosis, and western blot to detect protein expression of tgfβ and p-smad3. |
2024-08-27 |
2024-08-30 |
Not clear |
| Li Cao, Xintao Jing, Lijuan Liu, Hui Wang, Jiaqi Zhu, Jing Zhou, Hang Peng, Jinyuan Zhang, Fang Li, Xiaofei Wang, Le Zha. MZT2A serves as a prognostic biomarker and promotes the progression of kidney renal clear cell carcinoma. Heliyon. vol 10. issue 15. 2024-08-22. PMID:39170571. |
additionally, the effects of mzt2a on cell apoptosis and cell cycle were detected using flow cytometry and western blot. |
2024-08-22 |
2024-08-24 |
Not clear |
| Jiaxin Zhang, Huiqiong Han, Yihan Liu, Jiayao Xu, Daidi Zhang, Wenjia Wang, Yaping Gao, Zhengrui Li, Yanru Qi. SKF96365 Inhibits Tumor Proliferation by Inducing Apoptosis and Autophagy in Human Esophageal Squamous Cell Carcinoma. International journal of genomics. vol 2024. 2024-08-21. PMID:39165489. |
western blot and terminal deoxynucleotidyl transferase dutp nick end labeling (tunel) staining were used to detect cell apoptosis rates. |
2024-08-21 |
2024-08-23 |
mouse |
| Yu-Zheng He, Xiao-Ning Li, Hai-Tao Li, Xian-Hua Bai, Yan-Chao Liu, Fan-Nian Li, Bao-Lei Lv, Tian-Jie Qi, Xiu-Min Zhao, Shuai L. FTO promotes gefitinib-resistance by enhancing PELI3 expression and autophagy in non-small cell lung cancer. Pulmonary pharmacology & therapeutics. 2024-08-18. PMID:39154901. |
herein, using rt-qpcr, western blot, cell proliferation and apoptosis, as well as rna m6a modification assays, we substantiated that heightened fto (fat mass and obesity-associated protein) expression substantially underpins the emergence of gefitinib resistance in nsclc cells. |
2024-08-18 |
2024-08-21 |
human |
| Yomna Elleithi, Amal El-Gayar, Mohamed N Ami. Autophagy modulation attenuates sorafenib resistance in HCC induced in rats. Cell death & disease. vol 15. issue 8. 2024-08-16. PMID:39152108. |
western blot, elisa, immunohistochemistry, flow cytometry, and quantitative-pcr were used to investigate autophagy, apoptosis, and the cell cycle. |
2024-08-16 |
2024-08-20 |
rat |
| Xing Wu, Yixiang Tian, Na Zhang, Yangguang Ren, Zihao Zhang, Yudian Zhao, Yulong Guo, Yujie Gong, Yanhua Zhang, Donghua Li, Hong Li, Ruirui Jiang, Guoxi Li, Xiaojun Liu, Xiangtao Kang, Yadong Tia. The role of AdipoQ on proliferation, apoptosis, and hormone Secretion in chicken primary adenohypophysis cells. Poultry science. vol 103. issue 10. 2024-08-14. PMID:39142032. |
in this study, we investigated the effects of adipoq on proliferation, apoptosis, secretion of related hormones (fsh, lh, tsh, gh, prl and acth) and expression of related genes (fshβ, lhβ, gnrhr, tshβ, gh, prl and acth) in primary adenohypophysis cells of chickens by using real-time fluorescent quantitative pcr (rt-qpcr), cell counting kit-8 (cck-8), flow cytometry, enzyme-linked immunosorbent assay (elisa) and western blot (wb) assays. |
2024-08-14 |
2024-08-17 |
chicken |
| Kaiyu Huang, Chenchen Cai, Hualing He, Binghua Yi, Wencai Xu, Zhonghao Lin, Xiao Lv, Ronghua Liu, Cheng Zheng, Yingying Zhou, Jiafeng Li. Promotion of Raf-1/ASK1 complex formation by corylin inhibits cell apoptosis in myocardial ischemia/reperfusion injury. International immunopharmacology. vol 140. 2024-08-12. PMID:39133953. |
tunel, annexin-v/pi double staining,ki67 immunohistochemistry, western blot analysis, and immunofluorescence were used to validate cell apoptosis level and raf-1/ask1 complex activity. |
2024-08-12 |
2024-08-16 |
Not clear |
| Huan Shi, Biaobiao Wang, Huilin Ma, Yunmei Li, Jiaqun Du, Bo Zhang, Yu Gao, Ying Liu, Chao W. Preparation of Biomimetic Selenium-Baicalein Nanoparticles and Their Targeted Therapeutic Application in Nonsmall Cell Lung Cancer. Molecular pharmaceutics. 2024-08-06. PMID:39106303. |
the results of mtt, flow cytometry, western blot, and cell immunofluorescence staining demonstrated that acm-sse-be promoted a549 cell apoptosis and inhibited cell proliferation. |
2024-08-06 |
2024-08-09 |
Not clear |
| Xiaoqi Nie, Rui Cheng, Pengfei Hao, Yuhong Guo, Gang Chen, Lei Ji, Lu Ji. MicroRNA-128-3p Affects Neuronal Apoptosis and Neurobehavior in Cerebral Palsy Rats by Targeting E3 Ubiquitin-Linking Enzyme Smurf2 and Regulating YY1 Expression. Molecular neurobiology. 2024-08-05. PMID:39102109. |
moreover, primary cortical neurons were used to establish the oxygen and glucose deprivation (ogd) model in vitro, cell viability was detected by cck-8 assay, neuronal apoptosis was assessed by flow cytometry and western blot, and the underlying mechanism between mir-128-3p, smurf2 and yy1 was verified by bioinformatics analysis, dual luciferase reporter assay, rip, co-ip, ubiquitination assay, western blot, and rt-qpcr.in vivo, mir-128-3p and yy1 expression was elevated, and smurf2 expression was decreased in brain tissues of hypoxic-ischemic cp rats. |
2024-08-05 |
2024-08-07 |
rat |
| Jinsen He, Lixin Huang, Linqi L. Idebenone protects the kidneys of rats with renovascular arterial hypertension by inhibiting oxidative stress and apoptosis. Cellular and molecular biology (Noisy-le-Grand, France). vol 70. issue 7. 2024-08-04. PMID:39097876. |
the apoptosis key proteins (bad, bax, caspase9, gsk-3β) were detected via western blot. |
2024-08-04 |
2024-08-06 |
rat |
| Jiao Zhao, Jingru Zhang, Xiaojing Tong, Lili Zhao, Rong Ca. TRIM47 inhibits cisplatin chemosensitivity and endoplasmic reticulum stress-induced apoptosis of ovarian cancer cells. Molecular and cellular probes. 2024-08-03. PMID:39096978. |
oc cell viability was assessed with a cell counting kit-8 assay and oc cell apoptosis was assessed using flow cytometry, caspase-3 and caspase-9 activity, and bax and bcl-2 expression assays while gene and protein expression were assessed using qrt-pcr and western blot assays. |
2024-08-03 |
2024-08-06 |
Not clear |
| Yadan Zhang, Xiaoyu Zhang, Tianhan Kai, Lin Zhang, Anping L. Lycium ruthenicum Murray derived exosome-like nanovesicles inhibit Aβ-induced apoptosis in PC12 cells via MAPK and PI3K/AKT signaling pathways. International journal of biological macromolecules. 2024-08-01. PMID:39089544. |
transcriptomic and western blot experiments indicate that lrm-elns can inhibit aβ-induced apoptosis in pc12 cells through the mapk and pi3k/akt signaling pathways, with mirnas playing a crucial role. |
2024-08-01 |
2024-08-05 |
Not clear |
| Min Ji, Shiqi Weng, Xia Li, Qin Xiao, Yan Tong, Yan Zhou, Tao Luo, Zhaoxia Li. Revitalizing premature ovarian failure: quercetin counteracts imatinib-induced apoptosis via the PI3K/AKT signaling pathway based on network pharmacology. Naunyn-Schmiedeberg's archives of pharmacology. 2024-07-29. PMID:39073414. |
western blot, tunel, and immunohistochemical staining confirmed that que promoted the pi3k/akt signaling pathway and reduced apoptosis in ima-induced pof mice. |
2024-07-29 |
2024-08-02 |
mouse |
| Chunli Hu, Mengli Yang, Xue Feng, Shuzhe Wang, Yanfen Ma, Yun M. miR-10167-3p targets TCF7L1 to inhibit bovine adipocyte differentiation and promote bovine adipocyte proliferation. Genomics. 2024-07-28. PMID:39069233. |
the mrna and protein expression of proliferation, differentiation, and apoptosis marker genes were detected using qpcr and western blot, respectively; lipid droplet synthesis was detected using oil red o, nile red, and bodipy staining; adipocyte proliferation was detected by edu; and apoptosis was detected using flow cytometry. |
2024-07-28 |
2024-08-02 |
cattle |
| Kai-Cheng Chan, Praveenkumar Basavaraj, Jui-Chen Tsai, Jonathan Viehoever, Bing-Yan Hsieh, Xin-Yu Li, Guan-Jhong Huang, Wen-Chin Huan. Evaluating the Therapeutic Effect of Hispidin on Prostate Cancer Cells. International journal of molecular sciences. vol 25. issue 14. 2024-07-27. PMID:39063105. |
furthermore, apoptosis was assessed by annexin v-fitc/pi staining and western blot analyses. |
2024-07-27 |
2024-07-29 |
Not clear |
| Song-Hao-Ran Sheng, Yu-Bin Li, Jia-Cheng Guo, Xiao-Lan Meng, Chen Wang, Miao He, Yu-Qiang Li, Hong-Zhi Su. [Huaier triggering mitochondria apoptosis in colorectal cancer cells through oxidative stress]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 12. 2024-07-23. PMID:39041095. |
western blot(wb) experiment was performed to determine apoptosis proteins and pink1/parkin pathway. |
2024-07-23 |
2024-07-25 |
Not clear |
| Lu Wang, Ran Luo, Yin-Xu Zhao, Yu Zou, Ming Bu, Yu Li. [Ergosterol peroxide inducing apoptosis of human hepatocellular carcinoma by regulating mitochondrial apoptosis pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 12. 2024-07-23. PMID:39041100. |
the effects of different concentrations of ep on the protein expression of mitochondrial apoptosis pathway-related proteins b cell lymphoma 2(bcl-2), cytochrome c(cyt-c), bcl-2-related x protein(bax), caspase-3, cleaved caspase-3, caspase-9, and cleaved caspase-9 were examined by using western blot. |
2024-07-23 |
2024-07-25 |
human |
| Yuan-Fang Fan, Xiao-Hui Su, Ying Xu, Xiang-Ying Kong, Li-Ling Liu, Ya-Ge Tian, Na Li. [Effect of triptolide on reproductive toxicity in female rats with Ⅱ type collagen induced arthritis]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 11. 2024-07-23. PMID:39041166. |
in vitro, the mouse chinese hamster ovary(cho) cell line was established, and after 24 hours of tp administration(30, 60, 120 nmol·l~(-1)), cell proliferation was detected by the thiazolyl blue tetrazolium bromide(mtt) method, apoptosis by the flow cytometry, and tgfβ3, smad3 and sf-1 protein expression in cells by the western blot method, and the nuclear entry of sf-1 was detected by immunofluorescence. |
2024-07-23 |
2024-07-25 |
mouse |
| Shicun Zhang, Wei Zou, Yan Leng, Zhuang Mu, Lan Zha. Neuroprotective Effects of Metformin on Cerebral Ischemia-Reperfusion Injury: Modulation of JNK and p38 MAP Kinase Signaling Pathways. Cell biochemistry and biophysics. 2024-07-23. PMID:39043960. |
cell viability was measured with cell counting kit-8 (cck-8), protein expression via western blot (wb), and apoptosis through flow cytometry. |
2024-07-23 |
2024-07-26 |
mouse |