| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ziwei Zhang, Minghao Gu, Gao He, Xiafei Yu, Junzhe Yang, Xian Wu, Xiaoqiang Zhang, Kaining Lu, Fangze Qian, Xiaoyue Shi, Jialu Xu, Minyu Zhuang, Xiaoan Liu, Yanhui Zh. LHX2 Is a Potential Biomarker and Associated with Immune Infiltration in Breast Cancer. Cancers. vol 15. issue 10. 2023-06-22. PMID:37345110. |
a western blot assay proved that lhx2 activated the pi3k/akt/mtor pathway and the apoptosis pathway. |
2023-06-22 |
2023-08-14 |
Not clear |
| Zheng Duan, Honglin Li, Bin Hu, Yun Li, Li Huan. [Tumor antigen-loaded dendritic cells combined with cytokine-induced killer (CIK) enhance the killing activity of human esophageal cancer cells by promoting ASK1 activation]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 6. 2023-06-21. PMID:37340918. |
annexin v-fitc/pi double staining was used to detect the apoptosis rate of cells, immunofluorescence staining to detect the expression of phosphorylated apoptotic signal-regulated kinase 1 (p-ask1) and western blot analysis to detect the expression of ask1 pathway related proteins. |
2023-06-21 |
2023-08-14 |
mouse |
| Xin Zhang, Xueqin Li, Liangyu Zhu, Guoquan Yin, Yuan Zhang, Kun Ly. [Viral myocarditis serum exosome-derived miR-320 promotes the apoptosis of mouse cardiomyocytes by inhibiting AKT/mTOR pathway and targeting phosphatidylinositol 3-kinase regulatory subunit 1 (Pik3r1)]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. vol 39. issue 6. 2023-06-21. PMID:37340920. |
flow cytometry was used to detect cardiomyocyte apoptosis rate, and the expression levels of b cell lymphoma 2 (bcl2) and bcl2-related x protein (bax) were tested by western blot analysis. |
2023-06-21 |
2023-08-14 |
mouse |
| Xuefeng Zhang, Zhikun Wang, Binbin Wang, Jingyi Li, Hui Yua. lncRNA OIP5-AS1 attenuates the osteoarthritis progression in IL-1β-stimulated chondrocytes. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-06-19. PMID:37333451. |
after the expression of oip5-as1 or mir-338-3p in interleukin (il)-1β-stimulated primary chondrocytes and chon-001 cells was manipulated, cell viability, proliferation, apoptosis rate, apoptosis-related protein (cleaved caspase-9, bax) expressions, extracellular matrix (ecm) (matrix metalloproteinase (mmp)-3, mmp-13, aggrecan, and collagen ii), pi3k/akt pathway, and mrna expressions of inflammatory factors (il-6 and il-8), oip5-as1, and mir-338-3p were determined by cell counting kit-8, edu, flow cytometry, western blot, and quantitative reverse transcription-polymerase chain reaction. |
2023-06-19 |
2023-08-14 |
Not clear |
| Xiaogang Huang, Xiongzhi He, Rongxian Qiu, Xuemei Xie, Fengfeng Zheng, Feihua Chen, Zhenting H. Unfolded protein response inhibits KAT2B/MLKL-mediated necroptosis of hepatocytes by promoting BMI1 level to ubiquitinate KAT2B. Open medicine (Warsaw, Poland). vol 18. issue 1. 2023-06-19. PMID:37333449. |
the expression levels of bmi1, kat2b, and proteins related to upr (p-eif2α, eif2α, atf4, and atf6), nf-κb (p65 and p-p65), apoptosis (cleaved caspase-3, bcl-2, and bax) and necroptosis (p-mlkl and mlkl) were determined by western blot. |
2023-06-19 |
2023-08-14 |
Not clear |
| Yang Geng, Pengfei Chen, Lei Zhang, Xiaojun Li, Chao Song, Xueting Wei, Huiyuan Gon. LncRNA MALAT1 regulates growth of carcinoma of the lung through modulating miR-338-3p/PYCR2 axis. Cellular and molecular biology (Noisy-le-Grand, France). vol 69. issue 4. 2023-06-17. PMID:37329534. |
lc cells' proliferation, apoptosis, and metastasis were all examined concerning malat1 utilizing the following techniques: edu, cck-8, western blot and flow cytometry. |
2023-06-17 |
2023-08-14 |
Not clear |
| Linlin Guo, Chaoying Liu, Chunyan Jiang, Yanhan Dong, Lynn Htet Htet Aung, Han Ding, Yanyan Ga. miR‑124 inhibits cardiomyocyte apoptosis in myocardial ischaemia‑reperfusion injury by activating mitochondrial calcium uniporter regulator 1. Molecular medicine reports. vol 28. issue 2. 2023-06-16. PMID:37326122. |
western blot showed that mir‑124 and mcur1 were upregulated in cardiomyocyte apoptosis induced by hydrogen peroxide (h |
2023-06-16 |
2023-08-14 |
Not clear |
| Taibang Chen, Xiaoqing He, Jing Wang, Di Du, Yongqing X. NT-3 Combined with TGF-β Signaling Pathway Enhance the Repair of Spinal Cord Injury by Inhibiting Glial Scar Formation and Promoting Axonal Regeneration. Molecular biotechnology. 2023-06-15. PMID:37318740. |
immunofluorescence, tunel and western blot analysis showed that compared with model group, the neun expression increased, and the apoptosis and col iv, ln, cspg, tenascin-c, sema 3 a, ephb2 and smad2/3 protein expression decreased significantly in the nt-3 and nt-3 + ly364947 groups; the condition was reversed in the nt-3 + tgf-β1 group compared with the nt-3 group. |
2023-06-15 |
2023-08-14 |
mouse |
| Zhaoqing Gong, Xinlei Shi, Weizhen Xu, Yuan Fang, Meijia Fang, Minhua Yao, Yu Jiang, Hongshu Sui, Mingjiu Lu. LncRNA PWRN2 promotes polycystic ovary syndrome progression via epigenetically reducing ATRX by recruiting LSD1. Reproductive biology. vol 23. issue 3. 2023-06-15. PMID:37320994. |
the protein levels of apoptosis markers and alpha thalassemia retardation syndrome x-linked (atrx) were determined by western blot. |
2023-06-15 |
2023-08-14 |
rat |
| Hajime Ishinaga, Yoshinaga Okugawa, Bo Hou, Feng He, Chengzeng Yin, Mariko Murata, Yuji Toiyama, Kazuhiko Takeuch. The role of miR-21 as a predictive biomarker and a potential target to improve the effects of chemoradiotherapy against head and neck squamous cell carcinoma. Journal of radiation research. 2023-06-14. PMID:37312615. |
western blot analysis suggested the programmed cell death 4 protein as a potential target of mir-21 in relation to apoptosis. |
2023-06-14 |
2023-08-14 |
human |
| Jialiang Lin, Xuanqi Zheng, Zhencheng Xiong, Qian Xiang, Yongzhao Zhao, Shuai Jiang, Zhuoran Sun, Dongwei Fan, Chuiguo Sun, Weishi L. DJ-1-mediated p62 degradation delays intervertebral disc degeneration by inhibiting apoptosis of nucleus pulposus cells. Apoptosis : an international journal on programmed cell death. 2023-06-10. PMID:37300741. |
after overexpression of dj-1 in npcs by lentiviral transfection, dcfh-da and mitosox fluorescent probes were used to evaluate the levels of reactive oxygen species (ros); while western blot, tunel staining, and caspase-3 activity were used to assess apoptosis. |
2023-06-10 |
2023-08-14 |
rat |
| Liangzi Cao, Hao Li, Xiaofang Liu, Yubang Wang, Bowen Zheng, Chengzhong Xing, Naijin Zhang, Jingwei Li. Expression and regulatory network of E3 ubiquitin ligase NEDD4 family in cancers. BMC cancer. vol 23. issue 1. 2023-06-08. PMID:37291499. |
nedd4 family members interacted proteins were enriched in various pathways including p53, akt, apoptosis and autophagy, which were confirmed by further western blot and flow cytometric analysis in a549 and h1299 lung cancer cells. |
2023-06-08 |
2023-08-14 |
Not clear |
| Zong-Xing Zhang, Lu Jiang, Dao-Zhong Liu, Bo-Nan Tao, Zi-Ming Hou, Meng-Jie Tian, Jia Feng, Lin Yua. [Alcohol extract of root and root bark of Toddalia asiatica alleviates CIA in rats through anti-inflammatory and proapoptotic effects]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 8. 2023-06-07. PMID:37282908. |
in addition, rt-qpcr and western blot results showed that taae up-regulated the level of bax, down-regulated the level of bcl-2, and activated caspase-3 to promote apoptosis in synoviocytes. |
2023-06-07 |
2023-08-14 |
rat |
| Haoyu Zhang, Kexin Sun, Meichen Gao, Shiwen X. Zinc Inhibits Lead-Induced Oxidative Stress and Apoptosis of ST Cells Through ROS/PTEN/PI3K/AKT Axis. Biological trace element research. 2023-06-03. PMID:37269454. |
based on this information, we treated st cells with pb and zn and detected related indices such as apoptosis, oxidative stress, and the pten/pi3k/akt pathway using flow cytometry, dcfh-da staining, rt-pcr, and western blot. |
2023-06-03 |
2023-08-14 |
human |
| Ling Zuo, Yang Hai, Ruoyu Zhang, Biao Zuo, Jiayu Tian, Pan Li, Xiumei Ke, Meng Wang, Li Ren, Xuezhi Li, Xuekuan Huang, Jianwei Wan. Therapeutic potential of icariin in rats with letrozole and high-fat diet-induced polycystic ovary syndrome. European journal of pharmacology. 2023-06-03. PMID:37269973. |
combined with the ovarian transcriptome, we verified the key markers of apoptosis and the janus kinase/signal transducer and activator of transcription (jak/stat) signaling pathway by rt-qpcr for mrna level, western blot, and immunohistochemistry for protein expression. |
2023-06-03 |
2023-08-14 |
rat |
| Xiaozhou Wang, Hongyan Li, Jie Wang, Huiling Xu, Kun Xue, Xiaoting Liu, Zhizhong Zhang, Jianzhu Liu, Yongxia Li. Staphylococcus aureus extracellular vesicles induce apoptosis and restrain mitophagy-mediated degradation of damaged mitochondria. Microbiological research. vol 273. 2023-06-02. PMID:37267814. |
meanwhile, western blot and confocal microscopy detected mitochondrial damage, apoptosis, and parkin-mediated mitophagy. |
2023-06-02 |
2023-08-14 |
cattle |
| Yanyun Zhao, Sihan Huang, Renwei Xie, Jun Li. Extracellular ATP accelerates cell death and decreases tight junction protein ZO-1 in hypoxic cochlear strial marginal cells in neonatal rats. Cellular signalling. 2023-05-28. PMID:37245680. |
flow cytometry and western blot analyses revealed an increase in apoptosis levels and suppression of autophagy, indicating that eatp causes additional cell death by increasing the apoptosis of hypoxic mcs. |
2023-05-28 |
2023-08-14 |
rat |
| Qi Wang, Jia-Fei Xie, Ting-Ting Yao, Xu-Xu Wang, Qian-Wen Guo, Lu-Shan Wang, Yue Yu, Li-Chun X. MicroRNA‑30a‑5p regulates cypermethrin-induced apoptosis of Sertoli cells by targeting KLF9 in vitro. Reproductive toxicology (Elmsford, N.Y.). 2023-05-28. PMID:37245696. |
the apoptosis of tm4 cells, the expression level of mir-30a-5p, the protein expressions and the interaction between mir-30a-5p and klf9 were detected by flow cytometry, quantitative real-time pcr, western blot and luciferase reporter assays. |
2023-05-28 |
2023-08-14 |
mouse |
| Vicente Andreu-Fernández, Mariona Serra-Delgado, Laura Almeida-Toledano, Àgueda García-Meseguer, Melina Vieiros, Anna Ramos-Triguero, Concha Muñoz-Lozano, Elisabet Navarro-Tapia, Leopoldo Martínez, Óscar García-Algar, María D Gómez-Roi. Effect of Postnatal Epigallocatechin-Gallate Treatment on Cardiac Function in Mice Prenatally Exposed to Alcohol. Antioxidants (Basel, Switzerland). vol 12. issue 5. 2023-05-27. PMID:37237934. |
heart biomarkers of apoptosis, oxidative stress, and cardiac damage were analyzed by western blot. |
2023-05-27 |
2023-08-14 |
mouse |
| Shujuan Liu, Qiqi Bu, Jiashun Tong, Zhanhang Wang, Jiuzeng Cui, Heran Cao, Haidong Ma, Binyun Cao, Xiaopeng An, Yuxuan Son. miR-486 Responds to Apoptosis and Autophagy by Repressing SRSF3 Expression in Ovarian Granulosa Cells of Dairy Goats. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37240097. |
here, we identified and characterized mir-486 interaction with ser/arg-rich splicing factor 3 (srsf3) using luciferase reporter analysis, detecting its role in gc survival, apoptosis and autophagy regulation through qrt-pcr, western blot, cck-8, edu, flow cytometry, mitochondrial membrane potential and monodansylcadaverine, etc. |
2023-05-27 |
2023-08-14 |
Not clear |