| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Na Li, Qiaoqiao Sun, Zhengze Yu, Xiaonan Gao, Wei Pan, Xiuyan Wan, Bo Tan. Nuclear-Targeted Photothermal Therapy Prevents Cancer Recurrence with Near-Infrared Triggered Copper Sulfide Nanoparticles. ACS nano. vol 12. issue 6. 2019-09-30. PMID:29894162. |
under the irradiation of 980 nm near-infrared laser, the nps rapidly increase the temperature of the nucleus, destroy the genetic substances, and ultimately lead to an exhaustive apoptosis of the cancer cells. |
2019-09-30 |
2023-08-13 |
Not clear |
| Tzlil Bejerano, Sharon Etzion, Sigal Elyagon, Yoram Etzion, Smadar Cohe. Nanoparticle Delivery of miRNA-21 Mimic to Cardiac Macrophages Improves Myocardial Remodeling after Myocardial Infarction. Nano letters. vol 18. issue 9. 2019-09-12. PMID:30141949. |
following intravenous administration, the mirna-21 nps were targeted to cardiac macrophages at the infarct zone, elicited their phenotype switch from pro-inflammatory to reparative, promoted angiogenesis, and reduced hypertrophy, fibrosis and cell apoptosis in the remote myocardium. |
2019-09-12 |
2023-08-13 |
Not clear |
| Shefang Ye, Fanfan Wang, Zhongxiong Fan, Qixin Zhu, Haina Tian, Yubin Zhang, Beili Jiang, Zhenqing Hou, Yang Li, Guanghao S. Light/pH-Triggered Biomimetic Red Blood Cell Membranes Camouflaged Small Molecular Drug Assemblies for Imaging-Guided Combinational Chemo-Photothermal Therapy. ACS applied materials & interfaces. vol 11. issue 17. 2019-08-20. PMID:30964624. |
consequently, compared with individual treatment, rbcs@icg-hcpt nps under dual-stimuli accomplished highly efficient apoptosis in cancer cells and remarkable ablation of tumors by chemo-ptt. |
2019-08-20 |
2023-08-13 |
Not clear |
| Jeevitha Dhanapal, Malathy Balaraman Ravindrra. Chitosan/poly (lactic acid)-coated piceatannol nanoparticles exert an in vitro apoptosis activity on liver, lung and breast cancer cell lines. Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup1. 2019-08-19. PMID:29298541. |
these results suggested that upon cs/pla-pic nps exposure leads to decrease in cancer cell viability due to apoptosis. |
2019-08-19 |
2023-08-13 |
Not clear |
| Hao Wang, Xiwei Yu, Chang Su, Yijie Shi, Liang Zha. Chitosan nanoparticles triggered the induction of ROS-mediated cytoprotective autophagy in cancer cells. Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup1. 2019-08-19. PMID:29313384. |
the addition of blank nps produced a negative effect on cytotoxicity and cellular apoptosis of free dox, and with the pre-treatment of chloroquine (cq) as a known autophagy inhibitor, the inhibition rates of cells treated with the combination of dox and blank cs nps had been significantly increased. |
2019-08-19 |
2023-08-13 |
Not clear |
| Liuxiang Chu, Aiping Wang, Ling Ni, Xiuju Yan, Yina Song, Mingyu Zhao, Kaoxiang Sun, Hongjie Mu, Sha Liu, Zimei Wu, Chunyan Zhan. Nose-to-brain delivery of temozolomide-loaded PLGA nanoparticles functionalized with anti-EPHA3 for glioblastoma targeting. Drug delivery. vol 25. issue 1. 2019-08-14. PMID:30176744. |
glioma-bearing rats treated with anti-epha3-modified nps resulted in significantly higher tumor cell apoptosis (p < .01) than that observed with other formulations and prolonged the median survival time of glioma-bearing rats to 26 days, which was 1.37-fold longer than that of plga nps. |
2019-08-14 |
2023-08-13 |
rat |
| Mei-Lang Kung, Pei-Ying Lin, Shih-Tsung Huang, Ming-Hong Tai, Shu-Ling Hsieh, Chih-Chung Wu, Bi-Wen Yeh, Wen-Jeng Wu, Shuchen Hsie. Zingerone Nanotetramer Strengthened the Polypharmacological Efficacy of Zingerone on Human Hepatoma Cell Lines. ACS applied materials & interfaces. vol 11. issue 1. 2019-07-31. PMID:30566322. |
our results demonstrated that zingerone nps significantly inhibit akt activity and nfκb expression as well as activate the caspases cascade signaling pathway which are involved in the antiproliferation, antitumorigenicity, disturbing cell cycle progression, and induction of dna damage as well as cell apoptosis. |
2019-07-31 |
2023-08-13 |
human |
| Zhigao Wang, Rui Xue Zhang, Tian Zhang, Chunsheng He, Rong He, Xingrong Ju, Xiao Yu W. In Situ Proapoptotic Peptide-Generating Rapeseed Protein-Based Nanocomplexes Synergize Chemotherapy for Cathepsin-B Overexpressing Breast Cancer. ACS applied materials & interfaces. vol 10. issue 48. 2019-07-30. PMID:30387987. |
in an orthotopic breast tumor model of cathb-overexpressing breast cancer, dox-arpi/cs nps remarkably inhibit tumor growth, enhance tumor cell apoptosis and prolong host survival without eliciting any systemic toxicity. |
2019-07-30 |
2023-08-13 |
Not clear |
| Hadi Esmaeili Govarchin Ghaleh, Leila Zarei, Bahman Mansori Motlagh, Nasrollah Jabbar. Using CuO nanoparticles and hyperthermia in radiotherapy of MCF-7 cell line: synergistic effect in cancer therapy. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-07-22. PMID:30964344. |
a significant (p < .01) decrease in proliferation index (0.124 ± 0.021), a significant (p < .01) increase in apoptosis (42% ± 1.54) of mcf7 cells, a significant (p < .03) increase in ros formation (32.16 ± 1.9) and a significant (p < .01) increase in ldh release (33.28 ± 1.56) were recorded in the adjacency of mcf-7 cells by a combination of cuo nps (100 µg/ml) and r + h compared to control and other treatments. |
2019-07-22 |
2023-08-13 |
Not clear |
| Hadi Esmaeili Govarchin Ghaleh, Leila Zarei, Bahman Mansori Motlagh, Nasrollah Jabbar. Using CuO nanoparticles and hyperthermia in radiotherapy of MCF-7 cell line: synergistic effect in cancer therapy. Artificial cells, nanomedicine, and biotechnology. vol 47. issue 1. 2019-07-22. PMID:30964344. |
based on these observations, a combination of cuo nps, hyperthermia, and irradiation could suppress the growth of mcf-7 cells and evoke cell apoptosis via mitochondrial membrane potential. |
2019-07-22 |
2023-08-13 |
Not clear |
| Lulu Fan, Bingchen Zhang, Aixiao Xu, Zhichun Shen, Yan Guo, Ruirui Zhao, Huilu Yao, Jing-Wei Sha. Carrier-Free, Pure Nanodrug Formed by the Self-Assembly of an Anticancer Drug for Cancer Immune Therapy. Molecular pharmaceutics. vol 15. issue 6. 2019-07-03. PMID:29727577. |
ua nps exhibited higher antiproliferative activity; significantly caused apoptosis; decreased the expression of cox-2/vegfr2/vegfa; and increased the immunostimulatory activity of tnf-α, il-6, and ifn-β and decreased the activity of stat-3 in a549 cells in vitro. |
2019-07-03 |
2023-08-13 |
Not clear |
| Nasrollah Jabbari, Leila Zarei, Hadi Esmaeili Govarchin Galeh, Bahman Mansori Motlag. Assessment of synergistic effect of combining hyperthermia with irradiation and calcium carbonate nanoparticles on proliferation of human breast adenocarcinoma cell line (MCF-7 cells). Artificial cells, nanomedicine, and biotechnology. vol 46. issue sup2. 2019-06-24. PMID:29616844. |
our findings revealed that cc nps in combination with irradiation and hyperthermia could significantly reduce the cell viability and enhance the apoptosis of the mcf-7 breast cancer cells, the same as doxorubicin anti-cancer drug. |
2019-06-24 |
2023-08-13 |
human |
| Meeta Gera, Nameun Kim, Mrinmoy Ghosh, Neelesh Sharma, Do Luong Huynh, Nisansala Chandimali, Hyebin Koh, Jiao Jiao Zhang, Tae Yoon Kang, Yang Ho Park, Taeho Kwon, Dong Kee Jeon. Synthesis and evaluation of the antiproliferative efficacy of BRM270 phytocomposite nanoparticles against human hepatoma cancer cell lines. Materials science & engineering. C, Materials for biological applications. vol 97. 2019-06-17. PMID:30678901. |
taken together, our findings demonstrated that these uniquely engineered brm270 nps effectively enter into the cancer cells due to its acidic microenvironment thereby inducing apoptosis and regulate the cell-proliferation in-vitro at extremely low dosages. |
2019-06-17 |
2023-08-13 |
human |
| Wenjing Wang, Jie Liu, Wenjie Feng, Shulin Du, Rui Ge, Jing Li, Yi Liu, Hongchen Sun, Daqi Zhang, Hao Zhang, Bai Yan. Targeting mitochondria with Au-Ag@Polydopamine nanoparticles for papillary thyroid cancer therapy. Biomaterials science. vol 7. issue 3. 2019-06-14. PMID:30628592. |
in addition, despite cancer cells being able to survive by an autophagy-mediated pathway to escape apoptosis or necrosis, targeting mitochondria by au-ag@pda nps enables the destructive thermal ablation of tpc-1 cells by combination with photothermal therapy. |
2019-06-14 |
2023-08-13 |
human |
| Meimei Wang, Juan Wang, Yun Liu, Jingjing Wang, Yaguang Nie, Bo Si, Ying Liu, Xue Wang, Shaopeng Chen, Tom K Hei, Lijun Wu, Guoping Zhao, An X. Subcellular targets of zinc oxide nanoparticles during the aging process: role of cross-talk between mitochondrial dysfunction and endoplasmic reticulum stress in the genotoxic response. Toxicological sciences : an official journal of the Society of Toxicology. 2019-06-07. PMID:31173148. |
the present study found that the acute cytotoxic effects of fresh zno nps was largely regulated by mitochondria-dependent apoptosis, which the level of cleaved caspase-3 and mitochondria damage were significantly higher than that of 60 day-aged zno nps. |
2019-06-07 |
2023-08-13 |
cat |
| Akash Sharma, Brian Gorey, Alan Case. In vitro comparative cytotoxicity study of aminated polystyrene, zinc oxide and silver nanoparticles on a cervical cancer cell line. Drug and chemical toxicology. vol 42. issue 1. 2019-06-03. PMID:29359584. |
these findings suggest that all three nps resulted in the decrease in cell viability, increase intracellular ros production, induce cell cycle arrest at the g2/m phase and finally result in cell death by caspase-mediated apoptosis, which is irrespective of their differences in physiochemical properties and attached surface groups. |
2019-06-03 |
2023-08-13 |
Not clear |
| J Taylor, J Milton, M Willett, J Wingfield, S Mahaja. What do we actually see in intracellular SERS? Investigating nanosensor-induced variation. Faraday discussions. vol 205. 2019-05-31. PMID:28901362. |
while aunps are generally considered non-toxic to cells, many biological and toxicity studies report that exposure to nps induces cell stress through the generation of reactive oxygen species (ros) and the upregulated transcription of pro-inflammatory genes, which can result in severe genotoxicity and apoptosis. |
2019-05-31 |
2023-08-13 |
Not clear |
| Carolina Sánchez-Rodríguez, Raquel Palao-Suay, Laura Rodrigáñez, María Rosa Aguilar, Sergio Martín-Saldaña, Julio San Román, Ricardo Sanz-Fernánde. α-Tocopheryl Succinate-Based Polymeric Nanoparticles for the Treatment of Head and Neck Squamous Cell Carcinoma. Biomolecules. vol 8. issue 3. 2019-05-29. PMID:30235821. |
we analyzed the effect of the newly synthetized α-tos-loaded nps in proliferating endothelial cells and hypopharynx carcinoma squamous cells and measured markers of angiogenesis, apoptosis and reactive oxygen species (ros). |
2019-05-29 |
2023-08-13 |
Not clear |
| Carolina Sánchez-Rodríguez, Raquel Palao-Suay, Laura Rodrigáñez, María Rosa Aguilar, Sergio Martín-Saldaña, Julio San Román, Ricardo Sanz-Fernánde. α-Tocopheryl Succinate-Based Polymeric Nanoparticles for the Treatment of Head and Neck Squamous Cell Carcinoma. Biomolecules. vol 8. issue 3. 2019-05-29. PMID:30235821. |
α-tos-loaded nps suppressed angiogenesis by inducing accumulation of ros and inducing apoptosis of proliferating endothelial cells. |
2019-05-29 |
2023-08-13 |
Not clear |
| Sara Haji Hosseinali, Zahra Pourmokhtar Boushehri, Behnam Rasti, Mirsasan Mirpour, Koorosh Shahpasand, Mojtaba Falahat. Biophysical, molecular dynamics and cellular studies on the interaction of nickel oxide nanoparticles with tau proteins and neuron-like cells. International journal of biological macromolecules. vol 125. 2019-05-16. PMID:30528999. |
cytotoxic activity of nio nps against sh-sy5y cell was determined by trypan blue exclusion, cell morphology, ros, and apoptosis assays. |
2019-05-16 |
2023-08-13 |
Not clear |