| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hongliang Yu, Jian He, Qian Lu, Da Huo, Shanmei Yuan, Zhengyang Zhou, Peipei Xu, Yong H. Anti-Fas Antibody Conjugated Nanoparticles Enhancing the Antitumor Effect of Camptothecin by Activating the Fas-FasL Apoptotic Pathway. ACS applied materials & interfaces. vol 8. issue 44. 2018-10-16. PMID:27754664. |
results of western blot confirmed that these nps could mimic the function of activated cytotoxic lymphocyte (ctl) to activate the fas-fasl apoptosis pathway of tumor cells. |
2018-10-16 |
2023-08-13 |
Not clear |
| Priyanka Bhatnagar, Manisha Kumari, Richa Pahuja, A B Pant, Y Shukla, Pradeep Kumar, K C Gupt. Hyaluronic acid-grafted PLGA nanoparticles for the sustained delivery of berberine chloride for an efficient suppression of Ehrlich ascites tumors. Drug delivery and translational research. vol 8. issue 3. 2018-10-15. PMID:29441466. |
brb-d(ha)-g-plga nps were found to significantly enhance apoptosis, sub-g1 content, life span, mean survival time, and ros levels in eac cells with subsequent decrease in mitochondrial membrane potential and tumor burden ion tumor-bearing mice. |
2018-10-15 |
2023-08-13 |
mouse |
| Xiaoye Yang, Xiaoqun Shi, Jianbo Ji, Guangxi Zha. Development of redox-responsive theranostic nanoparticles for near-infrared fluorescence imaging-guided photodynamic/chemotherapy of tumor. Drug delivery. vol 25. issue 1. 2018-10-02. PMID:29542333. |
the improved therapeutic effect of ptx/cht nps compared with mono-photodynamic or mono-chemotherapy was observed in vitro via mtt and apoptosis assays. |
2018-10-02 |
2023-08-13 |
mouse |
| Peng Tian, Fan Wu, Jingyi Wang, Huashuang Ou, Xiang Liu, Qiujian Chen, Hua Dang, Yiqing Zheng, Xianghong Zhang, Hua Zo. Intralesional bleomycin A5 injection for the treatment of nasal polyps through inducing apoptosis. Acta oto-laryngologica. vol 138. issue 5. 2018-09-26. PMID:29490557. |
ble-induced apoptosis might play an important role in shrinkage of nps. |
2018-09-26 |
2023-08-13 |
Not clear |
| Yawei Li, Na Xu, Wenhe Zhu, Lei Wang, Bin Liu, Jianxu Zhang, Zhigang Xie, Wensen Li. Nanoscale Melittin@Zeolitic Imidazolate Frameworks for Enhanced Anticancer Activity and Mechanism Analysis. ACS applied materials & interfaces. vol 10. issue 27. 2018-09-17. PMID:29920061. |
the mechanism is well investigated by a series of transcriptome analysis, which indicates that mlt@zif-8 nps can regulate the expression of 3383 genes, and the pi3k/akt-regulated p53 pathway is involved in mlt@zif-8 nps induced a549 cells apoptosis. |
2018-09-17 |
2023-08-13 |
Not clear |
| P Chhay, M Murphy-Marion, Y Samson, D Girar. Activation of human eosinophils with palladium nanoparticles (Pd NPs): importance of the actin cytoskeleton in Pd NPs-induced cellular adhesion. Environmental toxicology and pharmacology. vol 57. 2018-08-27. PMID:29245060. |
pd nps did not significantly induce cell necrosis and apoptosis in eosinophils (0.5-150μg/ml) as assessed by trypan blue exclusion assay, flow cytometry after staining with fitc-annexin v and propidium iodide and by morphological observations by optical microscopy. |
2018-08-27 |
2023-08-13 |
human |
| Rohit Bisht, Ilva D Rupentha. PLGA nanoparticles for intravitreal peptide delivery: statistical optimization, characterization and toxicity evaluation. Pharmaceutical development and technology. vol 23. issue 4. 2018-08-21. PMID:27670289. |
developed nps were evaluated for potential toxicity and cell apoptosis using the zebrafish embryo toxicity (zet) model with titanium dioxide nps and ethanol (1% v/v) serving as positive controls. |
2018-08-21 |
2023-08-13 |
zebrafish |
| Rohit Bisht, Ilva D Rupentha. PLGA nanoparticles for intravitreal peptide delivery: statistical optimization, characterization and toxicity evaluation. Pharmaceutical development and technology. vol 23. issue 4. 2018-08-21. PMID:27670289. |
cellular apoptosis studies also endorsed the non-cytotoxic nature of the nps. |
2018-08-21 |
2023-08-13 |
zebrafish |
| Hanh Thuy Nguyen, Cao Dai Phung, Raj Kumar Thapa, Tung Thanh Pham, Tuan Hiep Tran, Jee-Heon Jeong, Sae Kwang Ku, Han-Gon Choi, Chul Soon Yong, Jong Oh Ki. Multifunctional nanoparticles as somatostatin receptor-targeting delivery system of polyaniline and methotrexate for combined chemo-photothermal therapy. Acta biomaterialia. vol 68. 2018-08-17. PMID:29292170. |
notably, lt-mtx/pani nps showed a greater uptake into sstr-positive cancer cells and thereby better inhibited cell viability and induced higher levels of apoptosis than mtx, pani np, and mtx/pani np treatments did. |
2018-08-17 |
2023-08-13 |
mouse |
| Jinsong Guo, Feihong Dong, Lian Ding, Kaile Wang, Jue Zhang, Jing Fan. A novel drug-free strategy of nano-pulse stimulation sequence (NPSS) in oral cancer therapy: In vitro and in vivo study. Bioelectrochemistry (Amsterdam, Netherlands). vol 123. 2018-08-15. PMID:29719274. |
nano-pulse stimulation (nps) is a novel technology to induce cancer apoptosis. |
2018-08-15 |
2023-08-13 |
Not clear |
| S Aurosman Pappus, Monalisa Mishr. A Drosophila Model to Decipher the Toxicity of Nanoparticles Taken Through Oral Routes. Advances in experimental medicine and biology. vol 1048. 2018-08-14. PMID:29453546. |
the nps, after oral route of exposure enter into the gut, crosses the barrier of peritrophic membrane and induces apoptosis. |
2018-08-14 |
2023-08-13 |
drosophila_melanogaster |
| Jun Kinoda, Masayuki Ishihara, Shingo Nakamura, Masanori Fujita, Koichi Fukuda, Yoko Sato, Hidetaka Yoko. Protective effect of FGF-2 and low-molecular-weight heparin/protamine nanoparticles on radiation-induced healing-impaired wound repair in rats. Journal of radiation research. vol 59. issue 1. 2018-08-10. PMID:29121251. |
we examined the effectiveness of localized administration of fibroblast growth factor-2 containing low-molecular-weight heparin/protamine nanoparticles (fgf-2&lmwh/p nps) on apoptosis in vivo and on healing of radiation-induced skin injury in a rat model. |
2018-08-10 |
2023-08-13 |
rat |
| Min-Chao Liu, Bing Liu, Xiang-Yu Sun, Hui-Chao Lin, Jia-Zheng Lu, Shu-Fang Jin, Si-Qi Yan, Yan-Yu Li, Ping Zha. Core/Shell Structured Fe₃O₄@TiO₂-DNM Nanospheres as Multifunctional Anticancer Platform: Chemotherapy and Photodynamic Therapy Research. Journal of nanoscience and nanotechnology. vol 18. issue 7. 2018-08-06. PMID:29442618. |
the cell apoptotic results revealed that the apoptosis induced by the fe3o4@tio2-dnm nps was in the early stage. |
2018-08-06 |
2023-08-13 |
Not clear |
| Vinay Kumar Tripathi, Allur Subramaniyan Sivakumar, Anupam Dhasmana, Inho Hwan. Crosstalk Between Co-Cultured 3T3-L1 and C2C12 Cells After the Exposure of Nano-Titanium Dioxide. Journal of nanoscience and nanotechnology. vol 18. issue 6. 2018-08-06. PMID:29442721. |
additionally, real-time pcr data analysis shown an increased in the expression of p53, bax, caspase-9, caspase-3 and decreased the level of bcl-2, by this means specifying that apoptosis induced by tio2 nps occurs via the caspase-dependent pathway. |
2018-08-06 |
2023-08-13 |
Not clear |
| Heng Zhang, Yu Jiang, XiaoLing Ni, LongXia Chen, Min Wu, Jing Liu, Bo Yang, Xu Shan, LingLin Yang, Juan Fan, Yue Chen, JingBo Wu, ShaoZhi F. Glycyrrhetinic Acid-Modified Norcantharidin Nanoparticles for Active Targeted Therapy of Hepatocellular Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 1. 2018-07-31. PMID:29463369. |
determination of cell apoptosis and cell cycle phase showed that at nps resulted in increased cell apoptosis and a distinct increase in the g2 phase (65.30 ± 3.52%, p < 0.01) and s phase (46.39 ± 1.39%, p < 0.01). |
2018-07-31 |
2023-08-13 |
mouse |
| Sivakumar Allur Subramaniyan, Sunirmal Sheet, Mohanraj Vinothkannan, Dong Jin Yoo, Yang Soo Lee, Shah Ahmed Belal, Kwan Seob Shi. One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown Journal of nanoscience and nanotechnology. vol 18. issue 5. 2018-07-30. PMID:29442810. |
moreover, the protein expression of both (i) apoptosis related proteins such as cas-3 and cas-9, (ii) inflammatory response proteins such as tnf-α, tgf-β and nf-κb were significantly upregulated in mg-pt nps treated cells than ng-pt nps treated cells. |
2018-07-30 |
2023-08-13 |
Not clear |
| Sivakumar Allur Subramaniyan, Sunirmal Sheet, Mohanraj Vinothkannan, Dong Jin Yoo, Yang Soo Lee, Shah Ahmed Belal, Kwan Seob Shi. One-Pot Facile Synthesis of Pt Nanoparticles Using Cultural Filtrate of Microgravity Simulated Grown Journal of nanoscience and nanotechnology. vol 18. issue 5. 2018-07-30. PMID:29442810. |
uptake and intracellular localization of mg-pt nps caused by accumulation of autophagosomes in c2c12 cells and bacterial cells, indicate that synthesized mg-pt nps enable for the swift cell apoptosis than ng-pt nps. |
2018-07-30 |
2023-08-13 |
Not clear |
| Ru Yuan, Huanli Xu, Xiaohui Liu, Ye Tian, Cong Li, Xiaoliang Chen, Shuonan Su, Ilana Perelshtein, Aharon Gedanken, Xiukun Li. Zinc-Doped Copper Oxide Nanocomposites Inhibit the Growth of Human Cancer Cells through Reactive Oxygen Species-Mediated NF-κB Activations. ACS applied materials & interfaces. vol 8. issue 46. 2018-07-18. PMID:27791350. |
hoechst 33342 staining and fitc-annexin v/pi staining showed that nzn-cuo nps could induce cell apoptosis in a dose dependent manner. |
2018-07-18 |
2023-08-13 |
human |
| Pawan K Mishra, Harshita Mishra, Adam Ekielski, Sushama Talegaonkar, Bhuvaneshwar Vaidy. Zinc oxide nanoparticles: a promising nanomaterial for biomedical applications. Drug discovery today. vol 22. issue 12. 2018-07-18. PMID:28847758. |
these activities are associated with the ability of zno nps to generate reactive oxygen species (ros) and induce apoptosis. |
2018-07-18 |
2023-08-13 |
Not clear |
| Yudong Song, Cui Tang, Chunhua Yi. Enhanced antitumor efficacy of arginine modified amphiphilic nanoparticles co-delivering doxorubicin and iSur-pDNA via the multiple synergistic effect. Biomaterials. vol 150. 2018-06-15. PMID:29028548. |
particularly, blank tas nps were selectively be toxic to tumor cells as evidenced by their capabilities to inhibit proliferation and induce apoptosis of tumor cells. |
2018-06-15 |
2023-08-13 |
mouse |