| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Richard Nuccitelli, Amanda McDaniel, Snjezana Anand, John Cha, Zachary Mallon, Jon Casey Berridge, Darrin Uecke. Nano-Pulse Stimulation is a physical modality that can trigger immunogenic tumor cell death. Journal for immunotherapy of cancer. vol 5. 2018-06-08. PMID:28428881. |
here we present evidence that nps stimulates both caspase 3/7 activation indicative of apoptosis, as well as the emission of three critical damps: ecto-calreticulin (crt), atp and hmgb1. |
2018-06-08 |
2023-08-13 |
Not clear |
| Yang Xiong, Yi Zhao, Lei Miao, C Michael Lin, Leaf Huan. Co-delivery of polymeric metformin and cisplatin by self-assembled core-membrane nanoparticles to treat non-small cell lung cancer. Journal of controlled release : official journal of the Controlled Release Society. vol 244. issue Pt A. 2018-05-24. PMID:27840166. |
cddp delivered with nanoparticles (nps) exhibited significantly increased tumor accumulation over free cddp and suppressed tumor growth through apoptosis in nsclc h460 tumor-bearing mice without nephrotoxicity. |
2018-05-24 |
2023-08-13 |
mouse |
| Yuan Zhao, Meng-Lei Huan, Miao Liu, Ying Cheng, Yang Sun, Han Cui, Dao-Zhou Liu, Qi-Bing Mei, Si-Yuan Zho. Doxorubicin and resveratrol co-delivery nanoparticle to overcome doxorubicin resistance. Scientific reports. vol 6. 2018-05-02. PMID:27731405. |
furthermore, dox/res-loaded nps could overcome dox resistance by inhibiting the expression of drug resistance-related protein such as p-gp, mrp-1 and bcrp, and induce apoptosis through down-regulating the expression of nf-κb and bcl-2. |
2018-05-02 |
2023-08-13 |
mouse |
| Allur Subramaniyan Sivakumar, Chandran Krishnaraj, Sunirmal Sheet, Dileep Reddy Rampa, Da Rae Kang, Shah Ahmed Belal, Abhay Kumar, In Ho Hwang, Soon-Il Yun, Yang Soo Lee, Kwan Seob Shi. Interaction of silver and gold nanoparticles in mammalian cancer: as real topical bullet for wound healing- A comparative study. In vitro cellular & developmental biology. Animal. vol 53. issue 7. 2018-04-09. PMID:28462492. |
the intracellular localization of ag and au nps in ht-1080 cells and their subsequent effect on apoptosis and necrosis were analyzed by flow cytometry while the mode of interaction was established by scanning electron microscopy under field emission mode and by bio-transmission electron microscopy. |
2018-04-09 |
2023-08-13 |
mouse |
| Allur Subramaniyan Sivakumar, Chandran Krishnaraj, Sunirmal Sheet, Dileep Reddy Rampa, Da Rae Kang, Shah Ahmed Belal, Abhay Kumar, In Ho Hwang, Soon-Il Yun, Yang Soo Lee, Kwan Seob Shi. Interaction of silver and gold nanoparticles in mammalian cancer: as real topical bullet for wound healing- A comparative study. In vitro cellular & developmental biology. Animal. vol 53. issue 7. 2018-04-09. PMID:28462492. |
these methods of analysis clearly revealed that the ag and au nps have easily entered and accumulated into the cytosol and nucleus, resulting in activation of inflammatory and apoptosis pathways, which in turn cause damage in dna. |
2018-04-09 |
2023-08-13 |
mouse |
| Yang Li, Guihua Liu, Jinyuan Ma, Jinyan Lin, Huirong Lin, Guanghao Su, Dengyue Chen, Shefang Ye, Xiaoyuan Chen, Xuan Zhu, Zhenqing Ho. Chemotherapeutic drug-photothermal agent co-self-assembling nanoparticles for near-infrared fluorescence and photoacoustic dual-modal imaging-guided chemo-photothermal synergistic therapy. Journal of controlled release : official journal of the Controlled Release Society. vol 258. 2018-03-29. PMID:28501673. |
moreover, in comparison with individual chemotherapy or ptt, the combinational chemo-ptt therapy of icg-epi nps with nir laser irradiation synergistically induced apoptosis and death of cancer cells in vitro, and showed synergistic chemo-ptt efficiency in vivo as evidenced by highly efficient tumor ablation. |
2018-03-29 |
2023-08-13 |
Not clear |
| Salma N Tammam, Hassan M E Azzazy, Alf Lamprech. The effect of nanoparticle size and NLS density on nuclear targeting in cancer and normal cells; impaired nuclear import and aberrant nanoparticle intracellular trafficking in glioma. Journal of controlled release : official journal of the Controlled Release Society. vol 253. 2018-03-21. PMID:28254629. |
however, to evade apoptosis and stimulate tumor growth cancer cells are capable of manipulating the nuclear-cytoplasmic transport on many levels, making nps that are capable of nuclear targeting in normal cells incapable of doing so in cancer. |
2018-03-21 |
2023-08-13 |
human |
| Fatemeh Ahmadi, Maryam Ghasemi-Kasman, Shahram Ghasemi, Maryam Gholamitabar Tabari, Roghayeh Pourbagher, Sohrab Kazemi, Ali Alinejad-Mi. Induction of apoptosis in HeLa cancer cells by an ultrasonic-mediated synthesis of curcumin-loaded chitosan-alginate-STPP nanoparticles. International journal of nanomedicine. vol 12. 2018-03-19. PMID:29238191. |
collectively, our results suggest that curcumin-loaded nps significantly suppressed proliferation and promoted the induction of apoptosis in human cervical epithelioid carcinoma cancer cells, which might be regarded as an effective alternative strategy for cancer therapy. |
2018-03-19 |
2023-08-13 |
human |
| Elanur Aydın, Hasan Türkez, Fazıl Hacımüftüoğlu, Abdulgani Tatar, Fatime Geyikoğl. Molecular genetic and biochemical responses in human airway epithelial cell cultures exposed to titanium nanoparticles in vitro. Journal of biomedical materials research. Part A. vol 105. issue 7. 2018-03-09. PMID:28028929. |
determining and analyzing the gene expression profiles of hpaepic and hppc cells, titanium nps showed more changes in genes related to dna damage or repair, oxidative stress, and apoptosis. |
2018-03-09 |
2023-08-13 |
human |
| Ding-Ping Bai, Xi-Feng Zhang, Guo-Liang Zhang, Yi-Fan Huang, Sangiliyandi Gurunatha. Zinc oxide nanoparticles induce apoptosis and autophagy in human ovarian cancer cells. International journal of nanomedicine. vol 12. 2018-03-08. PMID:28919752. |
therefore, this study was undertaken to investigate the effect of zno nps on cytotoxicity, apoptosis, and autophagy in human ovarian cancer cells (skov3). |
2018-03-08 |
2023-08-13 |
human |
| Zhilei Mao, Mengmeng Yao, Bo Xu, Xiaoli Ji, Hua Jiang, Xiumei Han, Qiusha Tang, Zuomin Zhou, Rui Chen, Xiaobo Li, Yankai Xi. Cytoskeletons of Two Reproductive Germ Cell Lines Response Differently to Titanium Dioxide Nanoparticles Mediating Vary Reproductive Toxicity. Journal of biomedical nanotechnology. vol 13. issue 4. 2018-02-23. PMID:29384604. |
our results showed that tio2 nps did not affect cell viability but induced cell apoptosis of both gc-2 and tm4 cells up to 100 μg/ml. |
2018-02-23 |
2023-08-13 |
Not clear |
| Zhilei Mao, Mengmeng Yao, Bo Xu, Xiaoli Ji, Hua Jiang, Xiumei Han, Qiusha Tang, Zuomin Zhou, Rui Chen, Xiaobo Li, Yankai Xi. Cytoskeletons of Two Reproductive Germ Cell Lines Response Differently to Titanium Dioxide Nanoparticles Mediating Vary Reproductive Toxicity. Journal of biomedical nanotechnology. vol 13. issue 4. 2018-02-23. PMID:29384604. |
totally tio2 nps is toxic to gc-2 cells by inducing cell apoptosis, disturbing microtubule arrangement and microtubule dynamic, and impairing cell migration ability. |
2018-02-23 |
2023-08-13 |
Not clear |
| Annapina Russo, Sara Maiolino, Valentina Pagliara, Francesca Ungaro, Fabiana Tatangelo, Alessandra Leone, Giulia Scalia, Alfredo Budillon, Fabiana Quaglia, Giulia Russ. Enhancement of 5-FU sensitivity by the proapoptotic rpL3 gene in p53 null colon cancer cells through combined polymer nanoparticles. Oncotarget. vol 7. issue 48. 2018-02-22. PMID:27835895. |
analysis of cytotoxicity and apoptotic induction potential of combined nps clearly showed that the 5-fu plus l3 were more effective in inducing apoptosis than 5-fu or l3 alone. |
2018-02-22 |
2023-08-13 |
Not clear |
| Brittany O'Donnell, Lily Huo, Joseph R Polli, Li Qiu, David N Collier, Baohong Zhang, Xiaoping Pa. From the Cover: ZnO Nanoparticles Enhanced Germ Cell Apoptosis in Caenorhabditis elegans, in Comparison with ZnCl2. Toxicological sciences : an official journal of the Society of Toxicology. vol 156. issue 2. 2018-02-15. PMID:28003440. |
effects of zno nps and ionic zn on germline apoptosis and the regulation of genes in the apoptosis pathway were investigated in vivo using the model organism caenorhabditis elegans.age synchronized bristol n2 worms were exposed to zno nps and zncl2 at concentrations of 6.14 × 10-1, 61.4, and 614 μm form larval stage 1 (l1) to early adulthood. |
2018-02-15 |
2023-08-13 |
caenorhabditis_elegans |
| Brittany O'Donnell, Lily Huo, Joseph R Polli, Li Qiu, David N Collier, Baohong Zhang, Xiaoping Pa. From the Cover: ZnO Nanoparticles Enhanced Germ Cell Apoptosis in Caenorhabditis elegans, in Comparison with ZnCl2. Toxicological sciences : an official journal of the Society of Toxicology. vol 156. issue 2. 2018-02-15. PMID:28003440. |
however, zno nps induced more apoptotic cells in the 61.4 μm treatment than zncl2 (p < .05), suggesting zno np is more potent in inducing apoptosis at specific exposure concentration. |
2018-02-15 |
2023-08-13 |
caenorhabditis_elegans |
| Brittany O'Donnell, Lily Huo, Joseph R Polli, Li Qiu, David N Collier, Baohong Zhang, Xiaoping Pa. From the Cover: ZnO Nanoparticles Enhanced Germ Cell Apoptosis in Caenorhabditis elegans, in Comparison with ZnCl2. Toxicological sciences : an official journal of the Society of Toxicology. vol 156. issue 2. 2018-02-15. PMID:28003440. |
therefore, the increased apoptosis resulting from zno nps exposure is likely cep-1/p53 dependent. |
2018-02-15 |
2023-08-13 |
caenorhabditis_elegans |
| Kyung Wook Heo, Seong Kook Park, Yeo Myeong Lee, Si Hong Choe, Pyung Mo Gu, Tae Ui Hong, Dae Young Hu. Methotrexate Induces Apoptosis in Organ-Cultured Nasal Polyps Via the Fas Pathway. The Journal of craniofacial surgery. vol 28. issue 3. 2018-02-09. PMID:28468172. |
methotrexate (mtx) is very effective when used to treat chronic inflammatory diseases, and also induces apoptosis in nasal polyps (nps). |
2018-02-09 |
2023-08-13 |
Not clear |
| Yan Li, Ruilong Zhang, Zhiguo Lu, Guanghui Ma, Lei Chen, Qunwei Tang, Xin Zhan. Microenvironment-Responsive Three-Pronged Approach Breaking Traditional Chemotherapy to Target Cancer Stem Cells for Synergistic Inoperable Large Tumor Therapy. Small (Weinheim an der Bergstrasse, Germany). vol 12. issue 40. 2018-02-05. PMID:27552926. |
the nps induce the apoptosis of differentiated cancer cells, cancer stem cells, and vascular niches simultaneously. |
2018-02-05 |
2023-08-13 |
Not clear |
| Jiang Pi, Jinhuan Jiang, Huaihong Cai, Fen Yang, Hua Jin, Peihui Yang, Jiye Cai, Zheng W Che. GE11 peptide conjugated selenium nanoparticles for EGFR targeted oridonin delivery to achieve enhanced anticancer efficacy by inhibiting EGFR-mediated PI3K/AKT and Ras/Raf/MEK/ERK pathways. Drug delivery. vol 24. issue 1. 2018-02-05. PMID:29019267. |
ge11-ori-se nps were found to induce cancer cell apoptosis by inducting reactive oxygen species (ros) production, activating mitochondria-dependent pathway, inhibiting egfr-mediated pi3k/akt and inhibiting ras/raf/mek/erk pathways. |
2018-02-05 |
2023-08-13 |
mouse |
| Huijuan Kuang, Pengfei Yang, Lin Yang, Zoraida P Aguilar, Hengyi X. Size dependent effect of ZnO nanoparticles on endoplasmic reticulum stress signaling pathway in murine liver. Journal of hazardous materials. vol 317. 2018-02-02. PMID:27262279. |
these findings implied that the smaller zno nps (30nm) activated er stress responses that signified severe apoptosis in murine liver. |
2018-02-02 |
2023-08-13 |
mouse |