| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hua-Peng Guan, Jian-Zhong Sun, Xiao-Lei Feng, Jin-Shui Chen, Fang-Jing Chen, Xiao-Fei Cheng, Xin-Wei Liu, Bin N. Effects of RNA interference-mediated knockdown of livin and survivin using monomethoxypolyethylene glycol-chitosan nanoparticles in MG-63 osteosarcoma cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26708654. |
mg-63 human osteosarcoma cells were transfected with short hairpin rna (shrna) against livin and survivin using monomethoxypolyethylene glycol‑chitosan (mpeg‑cs) nanoparticles (nps) as carriers, with the aim of evaluating the effect on cell proliferation and apoptosis. |
2016-10-31 |
2023-08-13 |
human |
| Hua-Peng Guan, Jian-Zhong Sun, Xiao-Lei Feng, Jin-Shui Chen, Fang-Jing Chen, Xiao-Fei Cheng, Xin-Wei Liu, Bin N. Effects of RNA interference-mediated knockdown of livin and survivin using monomethoxypolyethylene glycol-chitosan nanoparticles in MG-63 osteosarcoma cells. Molecular medicine reports. vol 13. issue 2. 2016-10-31. PMID:26708654. |
the simultaneous interference mediated by mpeg‑cs nps significantly reduced livin and survivin expression in mg‑63 cells, suppressed proliferation and facilitated apoptosis, to a greater extent than knockdown of either livin or survivin alone were. |
2016-10-31 |
2023-08-13 |
human |
| P C Nagajyothi, Muthuraman Pandurangan, T V M Sreekanth, Jaesool Shi. In vitro anticancer potential of BaCO3 nanoparticles synthesized via green route. Journal of photochemistry and photobiology. B, Biology. vol 156. 2016-10-31. PMID:26803273. |
immunofluorescence and fluorescence assays showed that baco3 nps increased the expression and activity of caspase-3, an autocatalytic enzyme that promotes apoptosis. |
2016-10-31 |
2023-08-13 |
Not clear |
| Francisco G Ortega, Martín A Fernández-Baldo, Jorge G Fernández, María J Serrano, María I Sanz, Juan J Diaz-Mochón, José A Lorente, Julio Rab. Study of antitumor activity in breast cell lines using silver nanoparticles produced by yeast. International journal of nanomedicine. vol 10. 2016-10-28. PMID:25844035. |
we analyzed cell viability, apoptosis induction, and endocytosis activity of those cell lines and we observed that the effects of the biosynthesized ag nps were directly related with the endocytosis activity. |
2016-10-28 |
2023-08-13 |
Not clear |
| Yuying Xue, Ting Zhang, Bangyong Zhang, Fan Gong, Yanmei Huang, Meng Tan. Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media. Journal of applied toxicology : JAT. vol 36. issue 3. 2016-10-25. PMID:26198703. |
this study evaluated the cellular proliferation and apoptosis of ag nps suspended in different solvents using human liver hepg2 cells. |
2016-10-25 |
2023-08-13 |
human |
| Yuying Xue, Ting Zhang, Bangyong Zhang, Fan Gong, Yanmei Huang, Meng Tan. Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media. Journal of applied toxicology : JAT. vol 36. issue 3. 2016-10-25. PMID:26198703. |
the effects of ag nps on cell cycle, induction of apoptosis, production of reactive oxygen species (ros) and mitochondrial membrane potential (mmp) were analyzed using flow cytometry. |
2016-10-25 |
2023-08-13 |
human |
| Yuying Xue, Ting Zhang, Bangyong Zhang, Fan Gong, Yanmei Huang, Meng Tan. Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media. Journal of applied toxicology : JAT. vol 36. issue 3. 2016-10-25. PMID:26198703. |
ag nps (40, 80 and 160 µg ml(-1)) exposure could cause cell-cycle arrest in the g2/m phase, significantly increasing the apoptosis rate and ros generation, and decreasing the mmp in hepg2 cells more sensitive to deionized water than in cell culture. |
2016-10-25 |
2023-08-13 |
human |
| Yuying Xue, Ting Zhang, Bangyong Zhang, Fan Gong, Yanmei Huang, Meng Tan. Cytotoxicity and apoptosis induced by silver nanoparticles in human liver HepG2 cells in different dispersion media. Journal of applied toxicology : JAT. vol 36. issue 3. 2016-10-25. PMID:26198703. |
these results suggested that the cellular toxicological mechanism of ag nps might be related to the oxidative stress of cells by the generation of ros, leading to mitochondria injury and induction of apoptosis. |
2016-10-25 |
2023-08-13 |
human |
| Wenxiu Hou, Xin Zhao, Xiaoqing Qian, Fei Pan, Chunlei Zhang, Yuming Yang, Jesús Martínez de la Fuente, Daxiang Cu. pH-Sensitive self-assembling nanoparticles for tumor near-infrared fluorescence imaging and chemo-photodynamic combination therapy. Nanoscale. vol 8. issue 1. 2016-10-14. PMID:26607263. |
moreover, the chemo-photodynamic combination therapy of tcad@ce6 nps combined with near-infrared laser irradiation was confirmed to be capable of inducing high apoptosis and necrosis of tumor cells (a549) in vitro and to display a significantly higher tumor growth suppression in the a549 lung cancer-bearing mice model. |
2016-10-14 |
2023-08-13 |
mouse |
| Song Gao, Jianfeng Li, Chen Jiang, Bo Hong, Bing Ha. Plasmid pORF-hTRAIL targeting to glioma using transferrin-modified polyamidoamine dendrimer. Drug design, development and therapy. vol 10. 2016-10-11. PMID:26719669. |
tunel assay revealed that tf-modified nps could induce much more tumor apoptosis. |
2016-10-11 |
2023-08-13 |
rat |
| Kui Wang, Forrest M Kievit, Mike Jeon, John R Silber, Richard G Ellenbogen, Miqin Zhan. Nanoparticle-Mediated Target Delivery of TRAIL as Gene Therapy for Glioblastoma. Advanced healthcare materials. vol 4. issue 17. 2016-10-10. PMID:26498165. |
transfected cells show threefold increased apoptosis as compared to the control dna bound nps. |
2016-10-10 |
2023-08-13 |
mouse |
| Fashui Hong, Xiaoyang Zhao, Ming Chen, Yingjun Zhou, Yuguan Ze, Ling Wang, Yajing Wang, Yushuang Ge, Qi Zhang, Lingqun Y. TiO2 nanoparticles-induced apoptosis of primary cultured Sertoli cells of mice. Journal of biomedical materials research. Part A. vol 104. issue 1. 2016-09-26. PMID:26238530. |
thus, our study was designed to examine the cellular viability, apoptosis, oxidative stress, antioxidant capacity, and expression of apoptotic cytokines in primary cultured sertoli cells isolated from mice under tio2 nps exposure. |
2016-09-26 |
2023-08-13 |
mouse |
| Fashui Hong, Xiaoyang Zhao, Ming Chen, Yingjun Zhou, Yuguan Ze, Ling Wang, Yajing Wang, Yushuang Ge, Qi Zhang, Lingqun Y. TiO2 nanoparticles-induced apoptosis of primary cultured Sertoli cells of mice. Journal of biomedical materials research. Part A. vol 104. issue 1. 2016-09-26. PMID:26238530. |
results showed that tio2 nps exposure from 5 to 30 μg/ml resulted in reduction of cell viability, lactate dehydrogenase release, and induction of apoptosis or death on sertoli cells. |
2016-09-26 |
2023-08-13 |
mouse |
| Manu Dalela, T G Shrivastav, Surender Kharbanda, Harpal Sing. pH-Sensitive Biocompatible Nanoparticles of Paclitaxel-Conjugated Poly(styrene-co-maleic acid) for Anticancer Drug Delivery in Solid Tumors of Syngeneic Mice. ACS applied materials & interfaces. vol 7. issue 48. 2016-09-26. PMID:26528585. |
confocal microscopy, western blotting, and flow cytometry results further supported that the cellular uptake and apoptosis of cancer cells with psmac-ptx nps. |
2016-09-26 |
2023-08-13 |
mouse |
| Manu Dalela, T G Shrivastav, Surender Kharbanda, Harpal Sing. pH-Sensitive Biocompatible Nanoparticles of Paclitaxel-Conjugated Poly(styrene-co-maleic acid) for Anticancer Drug Delivery in Solid Tumors of Syngeneic Mice. ACS applied materials & interfaces. vol 7. issue 48. 2016-09-26. PMID:26528585. |
administration of psmac-ptx nps showed significant tumor growth inhibition with improved apoptosis effects in vivo on ehrlich ascites tumor (eat)-bearing balb/c syngeneic mice in comparison with taxol, without showing any cytotoxicity. |
2016-09-26 |
2023-08-13 |
mouse |
| Paulo Emilio Feuser, Pamela Cristina Gaspar, Amanda Virtuoso Jacques, Antônio Claudio Tedesco, Maria Claudia Dos Santos Silva, Eduardo Ricci-Júnior, Claudia Sayer, Pedro Henrique Hermes de Araúj. Synthesis of ZnPc loaded poly(methyl methacrylate) nanoparticles via miniemulsion polymerization for photodynamic therapy in leukemic cells. Materials science & engineering. C, Materials for biological applications. vol 60. 2016-09-26. PMID:26706552. |
the results from fluorescence microscopy (eb/oa) and dna fragmentation suggest that the znpc loaded pmma nps induced cell death by apoptosis. |
2016-09-26 |
2023-08-13 |
human |
| Jun-Hyung Kim, Myeong Seon Jeong, Dong-Yung Kim, Song Her, Myung-Bok Wi. Zinc oxide nanoparticles induce lipoxygenase-mediated apoptosis and necrosis in human neuroblastoma SH-SY5Y cells. Neurochemistry international. vol 90. 2016-09-20. PMID:26364578. |
these results suggest that zno nps induce apoptosis via the pi3k/akt/caspase-3/7 pathway and necrosis by lox-mediated ros production elevation. |
2016-09-20 |
2023-08-13 |
human |
| Mohd Javed Akhtar, Hisham A Alhadlaq, Sudhir Kumar, Salman A Alrokayan, Maqusood Ahame. Selective cancer-killing ability of metal-based nanoparticles: implications for cancer therapy. Archives of toxicology. vol 89. issue 11. 2016-09-14. PMID:26223318. |
many in vitro and in vivo reports suggest that certain metal-based nps are able to induce apoptosis and autophagy in cancer cells at specific concentrations that are not significantly toxic to non-cancerous cells. |
2016-09-14 |
2023-08-13 |
Not clear |
| C Ganesh Kumar, Y Poornachandra, Cheemalamarri Chandrasekha. Green synthesis of bacterial mediated anti-proliferative gold nanoparticles: inducing mitotic arrest (G2/M phase) and apoptosis (intrinsic pathway). Nanoscale. vol 7. issue 44. 2016-09-07. PMID:26503300. |
mechanistic studies, such as ros, mmp, cyt-c, gsh, caspases 9, 8 and 3 activation and the annexin v-fitc staining, along with the above parameters tested provided sufficient evidence that the b-au nps induced apoptosis through the intrinsic pathway. |
2016-09-07 |
2023-08-13 |
human |
| Anne-Sophie Guedj, Arnold J Kell, Michael Barnes, Sandra Stals, David Gonçalves, Denis Girard, Carole Lavign. Preparation, characterization, and safety evaluation of poly(lactide-co-glycolide) nanoparticles for protein delivery into macrophages. International journal of nanomedicine. vol 10. 2016-08-31. PMID:26445538. |
plga nps were not cytotoxic for thp-1 mdm cells, did not modulate neutrophil apoptosis in vitro, and did not show inflammatory effect in vivo in the murine air pouch model of acute inflammation. |
2016-08-31 |
2023-08-13 |
human |