| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sara Haji Hosseinali, Zahra Pourmokhtar Boushehri, Behnam Rasti, Mirsasan Mirpour, Koorosh Shahpasand, Mojtaba Falahat. Biophysical, molecular dynamics and cellular studies on the interaction of nickel oxide nanoparticles with tau proteins and neuron-like cells. International journal of biological macromolecules. vol 125. 2019-05-16. PMID:30528999. |
nio nps also provided a significant impact on generating intracellular ros and apoptosis induction. |
2019-05-16 |
2023-08-13 |
Not clear |
| Somayeh Handali, Eskandar Moghimipour, Mohsen Rezaei, Sadegh Saremy, Farid Abedin Dorkoos. Co-delivery of 5-fluorouracil and oxaliplatin in novel poly(3-hydroxybutyrate-co-3-hydroxyvalerate acid)/poly(lactic-co-glycolic acid) nanoparticles for colon cancer therapy. International journal of biological macromolecules. vol 124. 2019-04-25. PMID:30248424. |
in the present study, a novel 5fu and oxa co-loaded phbv/plga nps was developed which induced apoptosis in cancer cells. |
2019-04-25 |
2023-08-13 |
Not clear |
| Jing Xia, Liuwei Zhang, Ming Qian, Yongming Bao, Jingyun Wang, Yachen L. Specific light-up pullulan-based nanoparticles with reduction-triggered emission and activatable photoactivity for the imaging and photodynamic killing of cancer cells. Journal of colloid and interface science. vol 498. 2019-04-18. PMID:28324723. |
in mcf-7 cells, compared to non-reducible p-ppix nps with stable amide linkages, p-s-s-ppix nps displayed higher cytotoxicity and induced higher apoptosis rate of tumor cells with light irradiation treatment. |
2019-04-18 |
2023-08-13 |
Not clear |
| Yonghong Wang, Baofang Wen, Hongli Yu, Dejun Ding, JingJing Zhang, Yunxiang Zhang, Limin Zhao, Weifen Zhan. Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 8. 2019-04-16. PMID:29903063. |
in this study, folate acid modified chitosan nanoparticles loaded berberine hydrochloride (bh/fa-cts nps) were prepared by the ionic cross-linking technique, the physicochemical properties and the influence of bh/fa-cts nps on proliferation, migration and apoptosis in human nasopharyngeal carcinoma cne-1 cells were studied in vitro and in vivo. |
2019-04-16 |
2023-08-13 |
human |
| Yonghong Wang, Baofang Wen, Hongli Yu, Dejun Ding, JingJing Zhang, Yunxiang Zhang, Limin Zhao, Weifen Zhan. Berberine Hydrochloride-Loaded Chitosan Nanoparticles Effectively Targets and Suppresses Human Nasopharyngeal Carcinoma. Journal of biomedical nanotechnology. vol 14. issue 8. 2019-04-16. PMID:29903063. |
bh/fa-cts nps promoted apoptosis and necrosis of cne-1 cells. |
2019-04-16 |
2023-08-13 |
human |
| Vivek K Pawar, Yuvraj Singh, Komal Sharma, Arpita Shrivastav, Abhisheak Sharma, Akhilesh Singh, Jaya Gopal Meher, Pankaj Singh, Kavit Raval, Animesh Kumar, Himangshu K Bora, Dipak Datta, Jawahar Lal, Manish K Chourasi. Improved chemotherapy against breast cancer through immunotherapeutic activity of fucoidan decorated electrostatically assembled nanoparticles bearing doxorubicin. International journal of biological macromolecules. vol 122. 2019-04-08. PMID:30219515. |
fcd nps offered improved cytotoxicity (2.64 folds), cell cycle arrest in g1-s phase (34.65%) and apoptosis (66.12%) in tumor cells compared to free dox. |
2019-04-08 |
2023-08-13 |
mouse |
| Tao Wang, Xin Wen, Yadong Hu, Xinyu Zhang, Dan Wang, Shaowu Yi. Copper nanoparticles induced oxidation stress, cell apoptosis and immune response in the liver of juvenile Takifugu fasciatus. Fish & shellfish immunology. vol 84. 2019-03-22. PMID:30366095. |
we investigated the effects of cu nps exposure on oxidative stress, apoptosis and immune response in an economically important model species, takifugu fasciatus. |
2019-03-22 |
2023-08-13 |
cat |
| Tao Wang, Xin Wen, Yadong Hu, Xinyu Zhang, Dan Wang, Shaowu Yi. Copper nanoparticles induced oxidation stress, cell apoptosis and immune response in the liver of juvenile Takifugu fasciatus. Fish & shellfish immunology. vol 84. 2019-03-22. PMID:30366095. |
oxidative stress indicators [malondialdehyde (mda), total superoxide dismutase (t-sod), catalase (cat) and glutathione (gsh)], apoptosis index and activities of caspases (caspase-3, caspase-9) were all increased with the increase of cu nps concentration in liver. |
2019-03-22 |
2023-08-13 |
cat |
| Yuki Takabayashi, Masahiro Kuwabara, Yoko Sato, Masayuki Ishihara, Megumi Takikawa, Shingo Nakamura, Koichi Fukuda, Sumiyo Hiruma, Tomoharu Kiyosaw. FGF-2-containing dalteparin/protamine nanoparticles (FGF-2&D/P NPs) ameliorate UV-induced skin photoaging in hairless mice. Journal of plastic surgery and hand surgery. vol 52. issue 6. 2019-03-20. PMID:30442053. |
thus, fgf-2&d/p nps may be effective in preventing skin photoaging accelerated by uvb irradiation such as declining elasticity, acanthosis, and apoptosis of dfcs and ekcs. |
2019-03-20 |
2023-08-13 |
mouse |
| Pengyu Chen, Han Wang, Man He, Beibei Chen, Bin Yang, Bin H. Size-dependent cytotoxicity study of ZnO nanoparticles in HepG2 cells. Ecotoxicology and environmental safety. vol 171. 2019-03-18. PMID:30616150. |
the internalization, cytotoxic mechanism, death mechanism and elimination behavior of three sizes of zno nps were studied by electrothermal vaporization (etv)-inductively coupled plasma mass spectrometry (icp-ms), mtt assays, gsh measurements, ros measurements and analyses of apoptosis and gene expression. |
2019-03-18 |
2023-08-13 |
Not clear |
| Behnaz Ghaemi, Elnaz Shaabani, Roqya Najafi-Taher, Saeedeh Jafari Nodooshan, Amin Sadeghpour, Sharmin Kharrazi, Amir Aman. Intracellular ROS Induction by Ag@ZnO Core-Shell Nanoparticles: Frontiers of Permanent Optically Active Holes in Breast Cancer Theranostic. ACS applied materials & interfaces. vol 10. issue 29. 2019-02-20. PMID:29932633. |
in this context, upregulation of apoptotic cascade proteins (i.e., bax/bcl2 association, p53, cytochrome c, and caspase-3) along with activation of oxidative stress proteins suggested the occurrence of apoptosis by ag@zno nps in cancer cells through the mitochondrial pathway. |
2019-02-20 |
2023-08-13 |
human |
| Benyu Su, Qiangdong Guan, Sufang Y. The neurotoxicity of nanoparticles: A bibliometric analysis. Toxicology and industrial health. vol 34. issue 12. 2019-02-13. PMID:30317940. |
the main research hot spots might focus on the pathogenesis of nps, such as oxidative stress and apoptosis. |
2019-02-13 |
2023-08-13 |
mouse |
| Shumei Wang, Liyun Qiu, Haiyan Song, Ningning Dan. NPS - 2143 (hydrochloride) inhibits melanoma cancer cell proliferation and induces autophagy and apoptosis. Medecine sciences : M/S. vol 34 Focus issue F1. 2019-02-13. PMID:30403181. |
nps - 2143 (hydrochloride) inhibits melanoma cancer cell proliferation and induces autophagy and apoptosis. |
2019-02-13 |
2023-08-13 |
human |
| Ying-Yi Chen, Yu-Jung Lin, Wei-Ting Huang, Chin-Chuan Hung, Hui-Yi Lin, Yu-Chen Tu, Dean-Mo Liu, Shou-Jen Lan, Ming-Jyh She. Demethoxycurcumin-Loaded Chitosan Nanoparticle Downregulates DNA Repair Pathway to Improve Cisplatin-Induced Apoptosis in Non-Small Cell Lung Cancer. Molecules (Basel, Switzerland). vol 23. issue 12. 2019-02-12. PMID:30563166. |
we aimed to understand whether dmc-chc nps efficiently potentiate cisplatin-induced apoptosis through downregulation of ercc1 in nsclc. |
2019-02-12 |
2023-08-13 |
Not clear |
| Qian Guo, Zengyan Chang, Naveed Ullah Khan, Tongtong Miao, Xiufeng Ju, Huaxiang Feng, Lei Zhang, Zhenglong Sun, Hui Li, Liang Ha. Nanosizing Noncrystalline and Porous Silica Material-Naturally Occurring Opal Shale for Systemic Tumor Targeting Drug Delivery. ACS applied materials & interfaces. vol 10. issue 31. 2019-02-11. PMID:30020771. |
interestingly, os nps possessed strong binding with the nuclear envelope, which can be beneficial to the nucleus localization and apoptosis inducing of loaded dox. |
2019-02-11 |
2023-08-13 |
Not clear |
| Nasim Rahmani Kukia, Yousef Rasmi, Ardeshir Abbasi, Nana Koshoridze, Alireza Shirpoor, George Burjanadze, Ehsan Saboor. Bio-Effects of TiO2 Nanoparticles on Human Colorectal Cancer and Umbilical Vein Endothelial Cell Lines Asian Pacific journal of cancer prevention : APJCP. vol 19. issue 10. 2019-02-06. PMID:30361551. |
results: exposure to increasing concentrations of tio2 nps enhanced overall cell survivalof hct116 cells and reduced the bcl-2 and caspase 3 expression while the ratio of bax/bcl-2 was down-regulated.tio2 nps at 400 and 50 μg/ml concentrations suppressed cell proliferation and induced apoptosis of ht29 cells andalso up-regulated p53 and bax at the mrna level, enhanced the bax/bcl-2 ratio and eventually up-regulated caspase3 mrna. |
2019-02-06 |
2023-08-13 |
human |
| N Sanoj Rejinold, Jisang Yoo, Sangyong Jon, Yeu-Chun Ki. Curcumin as a Novel Nanocarrier System for Doxorubicin Delivery to MDR Cancer Cells: In Vitro and In Vivo Evaluation. ACS applied materials & interfaces. vol 10. issue 34. 2019-02-04. PMID:30064206. |
the developed peg-coated crc/dox nanoparticles (nps) (peg-crc/dox nps) were well localized within the resistant cancer cells inducing apoptosis confirmed by flow cytometry and dna fragmentation assays. |
2019-02-04 |
2023-08-13 |
Not clear |
| Ruolan Wang, Bin Song, Junrong Wu, Yanli Zhang, Aijie Chen, Longquan Sha. Potential adverse effects of nanoparticles on the reproductive system. International journal of nanomedicine. vol 13. 2019-02-04. PMID:30587973. |
previous studies have shown that nps can increase inflammation, oxidative stress, and apoptosis and induce ros, causing damage at the molecular and genetic levels which results in cytotoxicity. |
2019-02-04 |
2023-08-13 |
Not clear |
| Hyungjoo Kim, Sunhwa Oh, Myung Chan Gye, Incheol Shi. Comparative toxicological evaluation of nonylphenol and nonylphenol polyethoxylates using human keratinocytes. Drug and chemical toxicology. vol 41. issue 4. 2019-01-30. PMID:29124983. |
nps and npeos also induced apoptosis and dna damage as shown by the activation of poly(adp-ribose) polymerase, caspase-3, and histone h2a.x. |
2019-01-30 |
2023-08-13 |
human |
| Yingming Sun, Hongtao Miao, Shijing Ma, Lei Zhang, Chengcheng You, Fang Tang, Cui Yang, Xiaoli Tian, Feng Wang, Yuan Luo, Xiangjie Lin, Hui Wang, Chunyang Li, Zhijun Li, Hongnv Yu, Xuefeng Liu, Yu Xiao, Yan Gong, Junhong Zhang, Hong Quan, Conghua Xi. FePt-Cys nanoparticles induce ROS-dependent cell toxicity, and enhance chemo-radiation sensitivity of NSCLC cells in vivo and in vitro. Cancer letters. vol 418. 2019-01-30. PMID:29331422. |
in the in vitro study, fept-cys nps induced a reactive oxygen species (ros) burst, which suppressed the antioxidant protein expression and induced cell apoptosis. |
2019-01-30 |
2023-08-13 |
Not clear |