| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Basini, S Bussolati, L Andriani, S Grolli, S Bertini, T Iemmi, A Menozzi, F Quintavalla, R Ramoni, P Serventi, F Grassell. The effects of nanoplastics on adipose stromal cells from swine tissues. Domestic animal endocrinology. vol 81. 2022-06-21. PMID:35728298. |
in organisms, nps can cross biological membranes, and cause oxidative stress, cell damage, apoptosis, and endocrine interference. |
2022-06-21 |
2023-08-14 |
Not clear |
| Wali Muhammad, Jiaqi Zhu, Zihe Zhai, Jieqi Xie, Jiahang Zhou, Xudong Feng, Bing Feng, Qiaoling Pan, Shifen Li, Rajiu Venkatesan, Pan Li, Hongcui Cao, Changyou Ga. ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment. Acta biomaterialia. 2022-06-20. PMID:35724918. |
the delivery of pftu@dex nps decreased the proportion of neutrophils significantly, mitigated the cell apoptosis remarkably compared to the other groups, reduced m1 macrophages and increased m2 macrophages in vivo. |
2022-06-20 |
2023-08-14 |
mouse |
| Wali Muhammad, Jiaqi Zhu, Zihe Zhai, Jieqi Xie, Jiahang Zhou, Xudong Feng, Bing Feng, Qiaoling Pan, Shifen Li, Rajiu Venkatesan, Pan Li, Hongcui Cao, Changyou Ga. ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment. Acta biomaterialia. 2022-06-20. PMID:35724918. |
therefore, the pftu@dex nps could efficiently suppress inflammatory cells, ros signaling pathways, and cell apoptosis to ameliorate lps-induced ali. |
2022-06-20 |
2023-08-14 |
mouse |
| Yan Xu, Jingqi Qi, Wei Sun, Wu Zhong, Hongwei W. Therapeutic Effects of Zoledronic Acid-Loaded Hyaluronic Acid/Polyethylene Glycol/Nano-Hydroxyapatite Nanoparticles on Osteosarcoma. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-13. PMID:35694235. |
the nps significantly enhanced the apoptosis-related protein expression and tumor cell apoptosis rate. |
2022-06-13 |
2023-08-14 |
mouse |
| Yan Xu, Jingqi Qi, Wei Sun, Wu Zhong, Hongwei W. Therapeutic Effects of Zoledronic Acid-Loaded Hyaluronic Acid/Polyethylene Glycol/Nano-Hydroxyapatite Nanoparticles on Osteosarcoma. Frontiers in bioengineering and biotechnology. vol 10. 2022-06-13. PMID:35694235. |
in the orthotopic osteosarcoma nude mice model, local injection of the ha-peg-nha-zol nps stimulated tumor necrosis, apoptosis, and granulocyte infiltration in the blood vessels. |
2022-06-13 |
2023-08-14 |
mouse |
| Hui Ming, Bowen Li, Hailong Tian, Li Zhou, Jingwen Jiang, Tingting Zhang, Ling Qiao, Peijie Wu, Edouard C Nice, Wei Zhang, Weifeng He, Canhua Huang, Haiyuan Zhan. A minimalist and robust chemo-photothermal nanoplatform capable of augmenting autophagy-modulated immune response against breast cancer. Materials today. Bio. vol 15. 2022-05-31. PMID:35634171. |
the ic/ir820 nps show an enhanced therapeutic effect on breast cancer by inducing reactive oxygen species (ros)-mediated apoptosis and autophagic death. |
2022-05-31 |
2023-08-13 |
mouse |
| Suliman A Alsagab. Transcriptomics-Based Investigation of Molecular Mechanisms Underlying Apoptosis Induced by ZnO Nanoparticles in Human Diffuse Large B-Cell Lymphoma. International journal of nanomedicine. vol 17. 2022-05-25. PMID:35611214. |
this study was set to assess the potential of zno nps to selectively induce apoptosis in human dlbcl cells (oci-ly3), and to describe possible molecular mechanisms of action. |
2022-05-25 |
2023-08-13 |
human |
| Yihan Wu, Jingjing Li, Xuemei Zhong, Jinfeng Shi, Yanfen Cheng, Chenglin He, Jiaxin Li, Liang Zou, Chaomei Fu, Meiwan Chen, Jinming Zhang, Huile Ga. A pH-sensitive supramolecular nanosystem with chlorin e6 and triptolide co-delivery for chemo-photodynamic combination therapy. Asian journal of pharmaceutical sciences. vol 17. issue 2. 2022-05-18. PMID:35582637. |
in view of the combination benefit of photodynamic therapy and chemotherapy, as well as co-encapsulation in the fabricated ph-sensitive supramolecular nps, tpl+ce6/nps exhibited significant efficacy to suppress cellular proliferation, boost ros level, lower mmp, and promote cellular apoptosis |
2022-05-18 |
2023-08-13 |
Not clear |
| Tapan Behl, Piyush Madaan, Aayush Sehgal, Sukhbir Singh, Hafiz A Makeen, Mohammed Albratty, Hassan A Alhazmi, Abdulkarim M Meraya, Simona Bunga. Demystifying the Neuroprotective Role of Neuropeptides in Parkinson's Disease: A Newfangled and Eloquent Therapeutic Perspective. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35562956. |
numerous nps, for instance, substance p (sp), ghrelin, neuropeptide y (npy), neurotensin, pituitary adenylate cyclase-activating polypeptide (pacap), nesfatin-1, and somatostatin, have been displayed to exhibit consequential neuroprotection in both in vivo and in vitro pd models via suppressing apoptosis, cytotoxicity, oxidative stress, inflammation, autophagy, neuronal toxicity, microglia stimulation, attenuating disease-associated manifestations, and stimulating chondriosomal bioenergetics. |
2022-05-14 |
2023-08-13 |
human |
| Wenwen Mu, Qi Wang, Mingxia Jia, Sijia Dong, Sijie Li, Jie Yang, Guoyun Li. Hepatoprotective Effects of Albumin-Encapsulated Nanoparticles of a Curcumin Derivative COP-22 against Lipopolysaccharide/D-Galactosamine-Induced Acute Liver Injury in Mice. International journal of molecular sciences. vol 23. issue 9. 2022-05-14. PMID:35563293. |
the anti-inflammatory activity of 22 nps is related to the regulation of the nf-κb signaling pathways; the antioxidant activity is related to the regulation of the nrf2 signaling pathways; and the apoptosis activity is related to mitochondrial pathways, involving bcl-2 family and caspase-3 protein. |
2022-05-14 |
2023-08-13 |
mouse |
| Xueling Yin, Siyi Ran, Haoyan Cheng, Meng Zhang, Wei Sun, Ying Wan, Chunsheng Shao, Zhihong Zh. Polydopamine-modified ZIF-8 nanoparticles as a drug carrier for combined chemo-photothermal osteosarcoma therapy. Colloids and surfaces. B, Biointerfaces. vol 216. 2022-05-06. PMID:35523102. |
biology assays in vitro indicated that the pda/mtx@zif-8 nps were able to efficiently induce mg63 cell apoptosis through reducing mitochondrial membrane potentials (mmps), and the introduction of photothermal agents enhanced the antitumor effect and decreased the dose of chemotherapeutic drugs. |
2022-05-06 |
2023-08-13 |
Not clear |
| Jing Zheng, Yixuan Sun, Tengfei Long, Dong Yuan, Song Yue, Ni Zhang, Zhu Yan. Sonosensitizer nanoplatform-mediated sonodynamic therapy induced immunogenic cell death and tumor immune microenvironment variation. Drug delivery. vol 29. issue 1. 2022-04-08. PMID:35393920. |
the antitumor effect of nps triggered by ultrasound (us) was measured by an apoptosis assay in a c57/bl6 mouse model. |
2022-04-08 |
2023-08-13 |
mouse |
| Jingxin Hou, Jun Zhou, Meiqi Chang, Guangcheng Bao, Jie Xu, Man Ye, Yixin Zhong, Shuling Liu, Junrui Wang, Wei Zhang, Haitao Ran, Zhigang Wang, Yu Chen, Dajing Gu. LIFU-responsive nanomedicine enables acoustic droplet vaporization-induced apoptosis of macrophages for stabilizing vulnerable atherosclerotic plaques. Bioactive materials. vol 16. 2022-04-07. PMID:35386311. |
ds, as a typical macrophages-targeted molecule, can achieve the precise vaporization of nps and subsequently controllable apoptosis of raw 264.7 macrophages as induced by acoustic droplet vaporization (adv) effect. |
2022-04-07 |
2023-08-13 |
Not clear |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
zinc oxide nanoparticles (zno nps) have exhibited excellent anti-tumor, the present study aimed to elucidate the underlying mechanism of zno nps induced apoptosis in acute myeloid leukemia (aml) cells by regulating mitochondrial division. |
2022-04-06 |
2023-08-13 |
human |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
next, the expression of drp-1, bcl-2, bax mrna and protein was detected, and the effects of zno nps on the levels of reactive oxygen species (ros), mitochondrial membrane potential (Δψm), apoptosis and atp generation in thp-1 cells were measured. |
2022-04-06 |
2023-08-13 |
human |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
zno nps can reduce the cell Δψm and atp levels, induce the ros production, and increase the levels of mitochondrial division and apoptosis. |
2022-04-06 |
2023-08-13 |
human |
| Xuewei Yin, Zonghong Li, Chunyi Lyu, Yan Wang, Shumin Ding, Chenchen Ma, Jingyi Wang, Siyuan Cui, Jinxin Wang, Dadong Guo, Ruirong X. Induced Effect of Zinc oxide nanoparticles on human acute myeloid leukemia cell apoptosis by regulating mitochondrial division. IUBMB life. 2022-04-06. PMID:35383422. |
in contrast, the apoptotic level was significantly reduced after intervention of drp-1 inhibitor, suggesting that zno nps can induce the apoptosis of thp-1 cells by regulating mitochondrial division. |
2022-04-06 |
2023-08-13 |
human |
| Sajedeh Daei, Roghayeh Abbasalipourkabir, Maryam Khajvand-Abedini, Nasrin Ziamajid. The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats. Biological trace element research. 2022-04-02. PMID:35364806. |
according to previous reports, zinc oxide (zno) nps cause toxic effects in tissues via inducing apoptosis. |
2022-04-02 |
2023-08-13 |
human |
| Sajedeh Daei, Roghayeh Abbasalipourkabir, Maryam Khajvand-Abedini, Nasrin Ziamajid. The Alleviative Efficacy of Vitamins A, C, and E Against Zinc Oxide Nanoparticles-Induced Hepatic Damage by Reducing Apoptosis in Rats. Biological trace element research. 2022-04-02. PMID:35364806. |
thus, administration of vits a, c, and e may be effective in preventing liver damage and apoptosis caused by zno nps. |
2022-04-02 |
2023-08-13 |
human |
| Xiangyang Zhang, Min Wang, Junyi Feng, Bin Qin, Chenglin Zhang, Chengshen Zhu, Wentao Liu, Yaohe Wang, Wei Liu, Lei Huang, Shuangshuang Lu, Zhimin Wan. Multifunctional nanoparticles co-loaded with Adriamycin and MDR-targeting siRNAs for treatment of chemotherapy-resistant esophageal cancer. Journal of nanobiotechnology. vol 20. issue 1. 2022-03-29. PMID:35346194. |
we have designed a novel and versatile self-assembling nanoparticle (np) platform on a multifunctional carboxymethyl chitosan base to simultaneously deliver adriamycin, and sirnas targeting mvp and bcl2 (ceamb nps), thus reducing drug efflux and promoting apoptosis of esophageal cancer cells. |
2022-03-29 |
2023-08-13 |
mouse |