| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chen Zhang, Wu Zhong, Ying Cao, Bohao Liu, Xiaojun Tao, Zhuan L. Sorafenib/2800Z Co-Loaded into Cholesterol and PEG Grafted Polylysine NPs for Liver Cancer Treatment. Pharmaceuticals (Basel, Switzerland). vol 16. issue 1. 2023-01-21. PMID:36678616. |
in addition, s2@pspc nps inhibited the proliferation and induced apoptosis of liver cancer cells in vitro. |
2023-01-21 |
2023-08-14 |
Not clear |
| Afraa Ali Kadhim, Nahida R Abbas, Hussam H Kadhum, Salim Albukhaty, Majid S Jabir, Amel Muhson Naji, Sawsan S Hamzah, Mustafa K A Mohammed, Hassan Al-Karagol. Investigating the Effects of Biogenic Zinc Oxide Nanoparticles Produced Using Papaver somniferum Extract on Oxidative Stress, Cytotoxicity, and the Induction of Apoptosis in the THP-1 Cell Line. Biological trace element research. 2023-01-20. PMID:36662347. |
this study investigated the effect of novel zinc oxide nanoparticles (zno nps) biosynthesized employing papaver somniferum leaf on oxidative stress, necrosis, and apoptosis in the leukemia cancer thp-1 cell. |
2023-01-20 |
2023-08-14 |
Not clear |
| Afraa Ali Kadhim, Nahida R Abbas, Hussam H Kadhum, Salim Albukhaty, Majid S Jabir, Amel Muhson Naji, Sawsan S Hamzah, Mustafa K A Mohammed, Hassan Al-Karagol. Investigating the Effects of Biogenic Zinc Oxide Nanoparticles Produced Using Papaver somniferum Extract on Oxidative Stress, Cytotoxicity, and the Induction of Apoptosis in the THP-1 Cell Line. Biological trace element research. 2023-01-20. PMID:36662347. |
thp-1 cells were subjected to an mtt, an edu proliferation, a lactate dehydrogenase release tests, a reactive oxygen species (ros) induction experiment, a dapi staining detection assay, and a flow cytometric analysis for annexin v to measure the effects of zno nps on cancer cell growth inhibition, apoptosis, and necrosis. |
2023-01-20 |
2023-08-14 |
Not clear |
| Afraa Ali Kadhim, Nahida R Abbas, Hussam H Kadhum, Salim Albukhaty, Majid S Jabir, Amel Muhson Naji, Sawsan S Hamzah, Mustafa K A Mohammed, Hassan Al-Karagol. Investigating the Effects of Biogenic Zinc Oxide Nanoparticles Produced Using Papaver somniferum Extract on Oxidative Stress, Cytotoxicity, and the Induction of Apoptosis in the THP-1 Cell Line. Biological trace element research. 2023-01-20. PMID:36662347. |
it was observed that zno nps triggered necrosis (cell death) and apoptosis in the cell line. |
2023-01-20 |
2023-08-14 |
Not clear |
| Yuanyuan He, Raimundo Fernandes de Araújo Júnior, Rômulo S Cavalcante, Zhenfeng Yu, Timo Schomann, Zili Gu, Christina Eich, Luis J Cru. Effective breast cancer therapy based on palmitic acid-loaded PLGA nanoparticles. Biomaterials advances. vol 145. 2023-01-05. PMID:36603405. |
at the molecular level, plga-pa nps reduced the expression of genes associated with multi-drug resistance and inhibition of apoptosis, and induced apoptosis via a caspase-3-independent pathway in breast cancer cells. |
2023-01-05 |
2023-08-14 |
mouse |
| Quan Sun, Hongqin Ma, Jiaxiong Zhang, Baiyang You, Xiaohui Gong, Xiaolin Zhou, Jin Chen, Guogang Zhang, Jia Huang, Qiong Huang, Yurong Yang, Kelong Ai, Yongping Ba. A Self-Sustaining Antioxidant Strategy for Effective Treatment of Myocardial Infarction. Advanced science (Weinheim, Baden-Wurttemberg, Germany). 2022-12-25. PMID:36567266. |
the therapeutic mechanism of ssse nps is intensively investigated through a series of experiments and mainly involved five critical aspects of myocardial repair: protecting mitochondria, reducing cardiomyocyte apoptosis and ferroptosis, reducing inflammation and fibrosis, and promoting angiogenesis. |
2022-12-25 |
2023-08-14 |
Not clear |
| Meimei Wang, Yu Feng, Zhenxiao Cao, Na Yu, Juan Wang, Xiaowei Wang, Dixiang Kang, Mingqin Su, Jian Hu, Hua D. Multiple generation exposure to ZnO nanoparticles induces loss of genomic integrity in Caenorhabditis elegans. Ecotoxicology and environmental safety. vol 249. 2022-12-12. PMID:36508841. |
we observed that pristine zno nps elicit germ cell apoptosis to a greater extent than the 60-day aged zno nps. |
2022-12-12 |
2023-08-14 |
caenorhabditis_elegans |
| Han Wang, Yilan Wu, Xiaoyan Li. Crizotinib loaded polydopamine-polylactide-TPGS nanoparticles in targeted therapy for non-small cell lung cancer. Medical oncology (Northwood, London, England). vol 40. issue 1. 2022-12-02. PMID:36459216. |
czt/pd-pt nps were synthesized and characterized, and their effects on pc-9 cell viability and apoptosis were determined. |
2022-12-02 |
2023-08-14 |
Not clear |
| Han Wang, Yilan Wu, Xiaoyan Li. Crizotinib loaded polydopamine-polylactide-TPGS nanoparticles in targeted therapy for non-small cell lung cancer. Medical oncology (Northwood, London, England). vol 40. issue 1. 2022-12-02. PMID:36459216. |
tunel assay and western blot were respectively applied for the determination of cell apoptosis and apoptosis-related protein expression, while liver function-related index expression detection and liver histopathological detection were used to evaluate the hepatotoxicity of czt/pd-pt nps. |
2022-12-02 |
2023-08-14 |
Not clear |
| Han Wang, Yilan Wu, Xiaoyan Li. Crizotinib loaded polydopamine-polylactide-TPGS nanoparticles in targeted therapy for non-small cell lung cancer. Medical oncology (Northwood, London, England). vol 40. issue 1. 2022-12-02. PMID:36459216. |
in addition, czt/pd-pt nps significantly inhibited pc-9 cell viability and promoted cell apoptosis both in vitro and in vivo, exhibiting superior cytotoxicity. |
2022-12-02 |
2023-08-14 |
Not clear |
| Zhihang Yang, Yufan Du, Lei Lei, Xue Xia, Xiaorong Wang, Fan Tong, Yuan Li, Huile Ga. Co-delivery of ibrutinib and hydroxychloroquine by albumin nanoparticles for enhanced chemotherapy of glioma. International journal of pharmaceutics. 2022-11-27. PMID:36436742. |
cck-8 and apoptosis assays demonstrated that ibr&hcq hsa nps showed maximal cytotoxicity to c6 cells. |
2022-11-27 |
2023-08-14 |
mouse |
| Azam Bozorgi, Zahra Haghighi, Mohammad Rasool Khazaei, Maryam Bozorgi, Mozafar Khazae. The anti-cancer effect of chitosan/resveratrol polymeric nanocomplex against triple-negative breast cancer; an in vitro assessment. IET nanobiotechnology. 2022-11-24. PMID:36420812. |
herein, the authors synthesised chitosan nanoparticles (cs nps) as a resveratrol (rsv) carrier and evaluated their efficacy in stimulating apoptosis in mda-mb 231 cells. |
2022-11-24 |
2023-08-14 |
Not clear |
| Maqusood Ahamed, Rashid Lateef, Mohd Javed Akhtar, Pavan Rajanahall. Dietary Antioxidant Curcumin Mitigates CuO Nanoparticle-Induced Cytotoxicity through the Oxidative Stress Pathway in Human Placental Cells. Molecules (Basel, Switzerland). vol 27. issue 21. 2022-11-11. PMID:36364205. |
the apoptosis data also exhibited that cuo nps modulate the expression of several genes (p53, bax, bcl-2, casp3, and casp9), the activity of enzymes (caspase-3 and -9), and mitochondrial membrane potential loss, which was successfully reverted by co-treatment with curcumin. |
2022-11-11 |
2023-08-14 |
human |
| Kuo-Wei Chen, Po-Hung Hsu, Hau-Lun Huang, Hao-Li Liu, Ya-Tin Lin, Che-Yu Hsu, Jui-Hsiang Lin, Yu-Hsin Li. Targeting nanoparticle-conjugated microbubbles combined with ultrasound-mediated microbubble destruction for enhanced tumor therapy. Pharmacological research. 2022-11-05. PMID:36334876. |
we demonstrated the transfer of targeted nps and their entry into gastric cancer cells through ligand-specific recognition, followed by enhanced cell growth inhibition owing to drug delivery-induced apoptosis. |
2022-11-05 |
2023-08-14 |
mouse |
| Parvin Ghasemi, Gholamreza Shafiee, Nasrin Ziamajidi, Roghayeh Abbasalipourkabi. Copper Nanoparticles Induce Apoptosis and Oxidative Stress in SW480 Human Colon Cancer Cell Line. Biological trace element research. 2022-10-24. PMID:36274109. |
as the effect of cunps on the induction of oxidative stress and apoptosis in the human colorectal cancer cell line sw480 has not yet been studied, we investigated the toxicity and mechanism of action of these nps in sw480 cells. |
2022-10-24 |
2023-08-14 |
human |
| Parvin Ghasemi, Gholamreza Shafiee, Nasrin Ziamajidi, Roghayeh Abbasalipourkabi. Copper Nanoparticles Induce Apoptosis and Oxidative Stress in SW480 Human Colon Cancer Cell Line. Biological trace element research. 2022-10-24. PMID:36274109. |
to investigate the effect of nps on cellular apoptosis, hoechst33258 staining was performed, and the expression of bax, bcl-2, and p53 was evaluated by qrt-pcr. |
2022-10-24 |
2023-08-14 |
human |
| Yunrong Yang, Min Liu, Tianjiao Zhao, Qiaohui Chen, Yuqi Yang, Shuya Wang, Jinping Zhang, Guiming Deng, Kewei Sun, Yayun Nan, Ke Cao, Kelong Ai, Qiong Huan. Epigallocatechin-3-gallate Mo nanoparticles (EGM NPs) efficiently treat liver injury by strongly reducing oxidative stress, inflammation and endoplasmic reticulum stress. Frontiers in pharmacology. vol 13. 2022-10-24. PMID:36278211. |
egm nps effectively scavenged various ros and reduced cell apoptosis at the cellular level. |
2022-10-24 |
2023-08-14 |
Not clear |
| Juncan Li, Ming Yuan, Tong Qiu, Mengli Lu, Siwen Zhan, Yuting Bai, Mengjia Yang, Xia Liu, Xueqiong Zhan. A glutathione -sensitive drug delivery system based on carboxymethyl chitosan co-deliver Rose Bengal and oxymatrine for combined cancer treatment. Journal of biomaterials science. Polymer edition. 2022-10-22. PMID:36272104. |
furthermore, omt/cmcs-cys-rb nps could inhibit the pi3k/akt signaling pathway in oxidative stress, and realize tumor apoptosis through mitochondria-related pathways. |
2022-10-22 |
2023-08-14 |
Not clear |
| Wenwan Shi, Xia Cao, Qi Liu, Qin Zhu, Kai Liu, Tianwen Deng, Qingtong Yu, Wenwen Deng, Jiangnan Yu, Qilong Wang, Ximing X. Hybrid Membrane-Derived Nanoparticles for Isoliquiritin Enhanced Glioma Therapy. Pharmaceuticals (Basel, Switzerland). vol 15. issue 9. 2022-09-23. PMID:36145280. |
we also investigated the mechanism of the antitumor effect of isl@hm nps, which revealed a marked inhibition of tumor cell proliferation and promotion of senescence and apoptosis of tumor cells of the formulation. |
2022-09-23 |
2023-08-14 |
human |
| Courtney van Ballegooie, Nicole Wretham, Tanya Ren, Ioana-Mihaela Popescu, Donald T Yapp, Marcel B Ball. PEG Conjugated Zein Nanoparticles for In Vivo Use. Pharmaceutics. vol 14. issue 9. 2022-09-23. PMID:36145579. |
when the nps were cultured with cells for 72 h, no cytotoxicity or early signs of apoptosis were identified. |
2022-09-23 |
2023-08-14 |
mouse |