| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Asif Mohd Itoo, Milan Paul, Balaram Ghosh, Swati Biswa. Polymeric graphene oxide nanoparticles loaded with doxorubicin for combined photothermal and chemotherapy in triple negative breast cancer. Biomaterials advances. vol 153. 2023-07-12. PMID:37437383. |
the results demonstrated that the dox@go(mpp) (1/0.5) nps treatment with laser (+l) (808 nm) was highly efficient in inducing apoptosis, cell cycle arrest (g2/m) phase, significant cytotoxicity, mitochondrial membrane depolarization, ros generation, and photothermal effect leading to a higher proportion of cell death than free dox, and dox@go(mpp) (1/0.5) nps (-l). |
2023-07-12 |
2023-08-14 |
mouse |
| Abhishesh Kumar Mehata, Virendra Singh, Vikas, Nitesh Singh, Abhijit Mandal, Debabrata Dash, Biplob Koch, Madaswamy S Muth. Chitosan- ACS applied materials & interfaces. 2023-07-11. PMID:37433149. |
the nanoparticles (nps) were prepared by solvent evaporation using the ionic gelation method and characterized for particle size, zeta potential, polydispersity, surface morphology, surface chemistry, drug entrapment efficiency, cytotoxicity assay, cellular uptake, and apoptosis study. |
2023-07-11 |
2023-08-14 |
Not clear |
| De-Ping Wang, Jian Zheng, Fang-Ying Jiang, Li-Fei Wu, Mei-Yue Wang, Yu-Lan Wang, Chuan-Yue Qin, Jun-Ya Ning, Ji-Min Cao, Xin Zho. Facile and green fabrication of tumor- and mitochondria-targeted AIEgen-protein nanoparticles for imaging-guided photodynamic cancer therapy. Acta biomaterialia. 2023-07-06. PMID:37414113. |
the nps also presented a mitochondria-targeting ability, and efficiently generated reactive oxygen species (ros) upon visible light irradiation, making them valuable for inducing efficient mitochondrial dysfunction and intrinsic apoptosis in cancer cells. |
2023-07-06 |
2023-08-14 |
human |
| Yuanying Zhang, Nan Yang, Ziyi Dong, Jiahui Wu, Rui Liao, Yanling Zhang, Gege Zhang, Mengfei Ren, Feng Wang, Xiaochen Dong, Pingping Lian. Dual-Targeting Biomimetic Nanomaterials for Photo-/Chemo-/Antiangiogenic Synergistic Therapy. ACS applied materials & interfaces. 2023-07-03. PMID:37400422. |
the mbpp nps exhibit high biocompatibility, superb phototoxicity, excellent antiangiogenic ability, and double-trigging cancer cell apoptosis in vitro. |
2023-07-03 |
2023-08-14 |
Not clear |
| Xia Cao, Tianwen Deng, Qin Zhu, Jianping Wang, Wenwan Shi, Qi Liu, Qintong Yu, Wenwen Deng, Jiangnan Yu, Qilong Wang, Gao Xiao, Ximing X. Photothermal Therapy Mediated Hybrid Membrane Derived Nano-formulation for Enhanced Cancer Therapy. AAPS PharmSciTech. vol 24. issue 6. 2023-06-28. PMID:37380936. |
compared to the normal section, pdt-mediated eg@emhm nps could induce an early stage of apoptosis of b16. |
2023-06-28 |
2023-08-14 |
Not clear |
| Fan Zhao, Hongyan Yu, Liying Liang, Chen Wang, Dier Shi, Xiangyu Zhang, Yao Ying, Wei Cai, Wangchang Li, Juan Li, Jingwu Zheng, Liang Qiao, Shenglei Che, Jing Y. Redox Homeostasis Disruptors Based on Metal-Phenolic Network Nanoparticles for Chemo/Chemodynamic Synergistic Tumor Therapy Through Activating Apoptosis and Cuproptosis. Advanced healthcare materials. 2023-06-27. PMID:37369362. |
herein, metal-phenolic network nanoparticles (nps) self-assembled from copper ions and gallic acid (cu-ga) are developed to evoke apoptosis and cuproptosis for synergistic chemo/chemodynamic therapy. |
2023-06-27 |
2023-08-14 |
Not clear |
| Kexin Zhang, Jiaxin Zhu, Ruyi Wang, Wanfang Zhu, Zhongtao Zhang, Liangping Gong, Feng Feng, Wenyuan Liu, Lingfei Han, Wei Q. Mitochondria-Anchoring Self-assembled Nanoparticles for Multi-Path Energy Depletion: A "Nano Bomb" in Chemo-co-Starvation Therapy. International journal of pharmaceutics. 2023-06-26. PMID:37364784. |
besides, apoptosis via mitochondria pathway and mitochondria fragmentation supported the hypothesis that nps eliminated mda-mb-231 cells by violently attacking mda-mb-231 cells and especially the mitochondria. |
2023-06-26 |
2023-08-14 |
Not clear |
| Zhuoting Lu, Jingyu Li, Baohong Chen, Jiayu Feng, Qinglian Hu, Yuanxiang Jin, Zhengwei F. Mitochondria Targeted Nanoparticles Potentiate Tumor Chemo-Phototherapy by Toxic Oxidative Stress Mediated Oxeiptosis. Macromolecular bioscience. 2023-06-09. PMID:37295777. |
also, m-icg-ptx nps exhibited higher tumor growth inhibition ability by promoting cell apoptosis and oxeiptosis pathway, and high effective inhibition of primary tumor growth and tumor metastasis. |
2023-06-09 |
2023-08-14 |
Not clear |
| Chenxi Zhu, Wenzong Zhou, Mingming Han, Ying Yang, Yiming Li, Qichen Jiang, Weiwei L. Dietary polystyrene nanoplastics exposure alters hepatic glycolipid metabolism, triggering inflammatory responses and apoptosis in Monopterus albus. The Science of the total environment. 2023-05-29. PMID:37247739. |
overexpression of the cytokines genes interleukin 1 (il1b) and interleukin-8 (il8), tumor necrosis factor alpha (tnf-α), activation of mapk signaling pathway, and increased gene expression of c-jun amino-terminal kinases (jnk) and p38 indicate that exposure to nps may lead to hepatopancreas apoptosis through oxidative stress and inflammation. |
2023-05-29 |
2023-08-14 |
cat |
| Fernanda M P Tonelli, Flávia C P Tonelli, Helon G Cordeir. TiO2 Nanoparticles in Cancer Therapy as Nanocarriers in Paclitaxel's Delivery and Nanosensitizers in Phototherapies and/or Sonodynamic Therapy. Current pharmaceutical biotechnology. 2023-05-19. PMID:37202892. |
signaling pathways triggered by this nanomaterial inside cells leading to apoptosis (a desirable fate when targeting tumor cells) and challenges related to the clinical translation of these nps will also receive attention in the future. |
2023-05-19 |
2023-08-14 |
Not clear |
| Jingyan Yi, Xin Luo, Jinshan Xing, Aharon Gedanken, Xiukun Lin, Chunxiang Zhang, Gan Qia. Micelle encapsulation zinc-doped copper oxide nanocomposites reverse Olaparib resistance in ovarian cancer by disrupting homologous recombination repair. Bioengineering & translational medicine. vol 8. issue 3. 2023-05-19. PMID:37206208. |
in addition to affecting cell proliferation, migration, apoptosis and autophagy, menzn-cuo nps have a greater potential for clinical application by inducing hr repair defects in ovarian cancer cells in combination with poly (adp-ribose) polymerase inhibitors for lethal effects. |
2023-05-19 |
2023-08-14 |
human |
| Yeneng Guan, Aqin Yan, Wei Qiang, Rui Ruan, Chaobo Yang, Kai Ma, Hongmei Sun, Mingxing Liu, Hongda Zh. Selective Delivery of Tofacitinib Citrate to Hair Follicles Using Lipid-Coated Calcium Carbonate Nanocarrier Controls Chemotherapy-Induced Alopecia Areata. International journal of molecular sciences. vol 24. issue 9. 2023-05-14. PMID:37176141. |
compared to the topical application of tfc solution, pl/acc-tfc nps significantly inhibited apoptosis of mouse hair follicles and accelerated hair growth. |
2023-05-14 |
2023-08-14 |
mouse |
| Yunhao Li, Yujuan Gao, Zian Pan, Fan Jia, Chenlu Xu, Xinyue Cui, Xuan Wang, Yan W. Fabrication of Poly Dopamine@poly (Lactic Acid-Co-Glycolic Acid) Nanohybrids for Cancer Therapy via a Triple Collaboration Strategy. Nanomaterials (Basel, Switzerland). vol 13. issue 9. 2023-05-14. PMID:37176991. |
in the drug-loaded pda co-delivery nanohybrids (pda@plga/dc nps), dox and ca4 synergistically induced tumor cell apoptosis by interfering with dna replication and inhibiting tumor angiogenesis, respectively. |
2023-05-14 |
2023-08-14 |
Not clear |
| Saima Maher, Shazia Nisar, Sania Muhammad Aslam, Farooq Saleem, Farida Behlil, Muhammad Imran, Mohammed A Assiri, Arifa Nouroz, Nadra Naheed, Zarmina Azad Khan, Parveen Asla. Synthesis and Characterization of ZnO Nanoparticles Derived from Biomass ( ACS omega. vol 8. issue 18. 2023-05-14. PMID:37179630. |
the zinc oxide (zno) nps can precisely and captivatingly promote the apoptosis of cancer cells in cancer treatment. |
2023-05-14 |
2023-08-14 |
Not clear |
| Mohamed Haider, Jayalakshmi Jagal, Khuloud Bajbouj, Basma M Sharaf, Lina Sahnoon, Javan Okendo, Mohammad H Semreen, Mawieh Hamda, Nelson C Soare. Integrated multi-omics analysis reveals unique signatures of paclitaxel-loaded poly(lactide-co-glycolide) nanoparticles treatment of head and neck cancer cells. Proteomics. 2023-05-06. PMID:37148169. |
functional cell assays revealed that ptx-plga nps treated cells had a higher level of apoptosis than ptx alone, whereas the complementary, uhplc-ms/ms (tims-tof) based multi-omics analyses revealed that ptx-plga nps treatment resulted in increased abundance of proteins associated with tubulin, as well as metabolites such as 5-thymidylic acid, pc(18:1(9z)/18:1(9z0), vitamin d, and sphinganine among others. |
2023-05-06 |
2023-08-14 |
Not clear |
| Zhengquan Nie, Fangdao Zhu, Shuai Chen, Junxin Xu, Jianmei Yang, Junnan He, Xiao-Qing Liu, Yan Zhao, Jin Zhan. A supramolecular nanovehicle featuring pH/enzyme co-response for targeted delivery of the antitumor compound. ChemPlusChem. 2023-05-03. PMID:37132411. |
furthermore, tpl@tscd/mcc nps containing relatively small amounts of tpl presented similar apoptosis rates to those of intrinsic tpl. |
2023-05-03 |
2023-08-14 |
Not clear |
| Shuang Liu, Han Zhou, Yang Shi, Simeng Yi, Xinyu Wang, Jingyan Li, Bin Liao, Jimin Cao, Guang L. Zinc Oxide Nanoparticles Induce Renal Injury by Initiating Oxidative Stress, Mitochondrial Damage and Apoptosis in Renal Tubular Epithelial Cells. Biological trace element research. 2023-04-29. PMID:37119342. |
mechanistically, zno nps promoted oxidative stress and mitochondrial damage by generating ros and induced apoptosis in hk-2 cells, as evidenced by the upregulation of bax and caspase 3 and downregulation of beclin 1. |
2023-04-29 |
2023-08-14 |
mouse |
| Shuang Liu, Han Zhou, Yang Shi, Simeng Yi, Xinyu Wang, Jingyan Li, Bin Liao, Jimin Cao, Guang L. Zinc Oxide Nanoparticles Induce Renal Injury by Initiating Oxidative Stress, Mitochondrial Damage and Apoptosis in Renal Tubular Epithelial Cells. Biological trace element research. 2023-04-29. PMID:37119342. |
in vivo, zno nps induced tubular epithelial cell apoptosis and increased serum creatinine, serum urea nitrogen, and urinary protein in mice, suggesting damage to renal structure and function. |
2023-04-29 |
2023-08-14 |
mouse |
| Jiaxin Zhu, Kexin Zhang, Ya Zhou, Ruyi Wang, Liangping Gong, Can Wang, Keke Zhong, Wenyuan Liu, Feng Feng, Wei Q. A Carrier-Free Nanomedicine Enables Apoptosis-Ferroptosis Synergistic Breast Cancer Therapy by Targeting Subcellular Organelles. ACS applied materials & interfaces. 2023-04-27. PMID:37104698. |
herein, carrier-free theranostic asp nanoparticles (nps) were designed for wiping out tnbc by synergistic apoptosis and ferroptosis, which was self-assembled by aurantiamide acetate (aa), scutebarbatine a (sa), and palmitin (p). |
2023-04-27 |
2023-08-14 |
Not clear |
| Hui Zhou, Yuqin Liao, Xiangfei Han, Dean Shuailin Chen, Xuechuan Hong, Kun Zhou, Xingya Jiang, Yuling Xiao, Jinjun Sh. ROS-Responsive Nanoparticle Delivery of mRNA and Photosensitizer for Combinatorial Cancer Therapy. Nano letters. 2023-04-24. PMID:37093620. |
the ros-triggered disassembly of the nps could promote mrna translation efficiency, whereby p53 expression induced apoptosis of lung tumor cells. |
2023-04-24 |
2023-08-14 |
Not clear |