| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Marchetti, S A Susin, D Decaudin, S Gamen, M Castedo, T Hirsch, N Zamzami, J Naval, A Senik, G Kroeme. Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer research. vol 56. issue 9. 1996-06-12. PMID:8616847. |
u937 cells lacking mitochondrial dna (rho [symbol: see text] cells) are auxotrophic for uridine and pyruvate, hypersensitive to hypoglycemic conditions, and resistant to antimycin a-induced apoptosis. |
1996-06-12 |
2023-08-12 |
Not clear |
| P Marchetti, S A Susin, D Decaudin, S Gamen, M Castedo, T Hirsch, N Zamzami, J Naval, A Senik, G Kroeme. Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA. Cancer research. vol 56. issue 9. 1996-06-12. PMID:8616847. |
similarly to rho + controls, rho [symbol: see text] cells undergo apoptosis in response to tumor necrosis factor-alpha plus cycloheximide. |
1996-06-12 |
2023-08-12 |
Not clear |
| P Esteve, L del Peso, J C Laca. Induction of apoptosis by rho in NIH 3T3 cells requires two complementary signals. Ceramides function as a progression factor for apoptosis. Oncogene. vol 11. issue 12. 1996-02-09. PMID:8545123. |
induction of apoptosis by rho in nih 3t3 cells requires two complementary signals. |
1996-02-09 |
2023-08-12 |
aplysia |
| P Esteve, L del Peso, J C Laca. Induction of apoptosis by rho in NIH 3T3 cells requires two complementary signals. Ceramides function as a progression factor for apoptosis. Oncogene. vol 11. issue 12. 1996-02-09. PMID:8545123. |
thus, rho proteins act as an initiation signal that is necessary but not sufficient for the induction of apoptosis in nih 3t3 cells. |
1996-02-09 |
2023-08-12 |
aplysia |
| B Jiménez, M Arends, P Esteve, R Perona, R Sánchez, S Ramón y Cajal, A Wyllie, J C Laca. Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily. Oncogene. vol 10. issue 5. 1995-04-25. PMID:7898922. |
we show that expression of wild-type rho from aplysia californica stimulates apoptosis in cultured cell lines and that the apoptotic index in tumors generated by these cell lines is similar to those induced by e1a-transformed cells. |
1995-04-25 |
2023-08-12 |
aplysia |
| B Jiménez, M Arends, P Esteve, R Perona, R Sánchez, S Ramón y Cajal, A Wyllie, J C Laca. Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily. Oncogene. vol 10. issue 5. 1995-04-25. PMID:7898922. |
in contrast, mutated rho, activated by val14 substitution in the gtp binding site, it less potent as a stimulator of apoptosis, generating a phenotype more similar to that obtained with activated ras. |
1995-04-25 |
2023-08-12 |
aplysia |
| B Jiménez, M Arends, P Esteve, R Perona, R Sánchez, S Ramón y Cajal, A Wyllie, J C Laca. Induction of apoptosis in NIH3T3 cells after serum deprivation by overexpression of rho-p21, a GTPase protein of the ras superfamily. Oncogene. vol 10. issue 5. 1995-04-25. PMID:7898922. |
thus, rho genes may play a critical role in the regulation of apoptosis. |
1995-04-25 |
2023-08-12 |
aplysia |