| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A L Kierszenbau. Decidualization and implantation: embryo-uterine bioinformatics at work. Molecular reproduction and development. vol 59. issue 2. 2001-10-18. PMID:11389546. |
with recent results hinting at the role of signaling proteins associated with the bone morphogenetic protein, fibroblast growth factor, wnt and hedgehog families to enable embryo implantation, the dynamics of uterine-embryo interaction becomes linked to fundamental cellular pathways of growth, differentiation and apoptosis. |
2001-10-18 |
2023-08-12 |
Not clear |
| S E Jones, C Jomary, J Grist, H J Stewart, M J Nea. Modulated expression of secreted frizzled-related proteins in human retinal degeneration. Neuroreport. vol 11. issue 18. 2001-03-29. PMID:11192610. |
inherited retinal degenerations such as retinitis pigmentosa (rp) are characterized by progressive loss of photoreceptors, apparently by apoptosis, and our recent report of increased secreted frizzled-related protein-2 (sfrp2) in rp retinas suggests altered wnt signalling may be a component of the degenerative process. |
2001-03-29 |
2023-08-12 |
human |
| S Chen, D C Guttridge, Z You, Z Zhang, A Fribley, M W Mayo, J Kitajewski, C Y Wan. Wnt-1 signaling inhibits apoptosis by activating beta-catenin/T cell factor-mediated transcription. The Journal of cell biology. vol 152. issue 1. 2001-03-01. PMID:11149923. |
given that numerous oncogenes transform cells by providing cell survival function, we hypothesized that wnt signaling may inhibit apoptosis. |
2001-03-01 |
2023-08-12 |
Not clear |
| G Van Gassen, W Annaert, C Van Broeckhove. Binding partners of Alzheimer's disease proteins: are they physiologically relevant? Neurobiology of disease. vol 7. issue 3. 2000-09-12. PMID:10860781. |
proteins interacting with the presenilins however are more diverse in nature linking presenilin function to regulation in different signaling pathways including wnt and notch but also in apoptosis and ca(2+) homeostasis. |
2000-09-12 |
2023-08-12 |
Not clear |
| A Patapoutian, L F Reichard. Roles of Wnt proteins in neural development and maintenance. Current opinion in neurobiology. vol 10. issue 3. 2000-08-24. PMID:10851180. |
wnt signaling has been demonstrated to regulate apoptosis and may participate in degenerative processes leading to cell death in the aging brain. |
2000-08-24 |
2023-08-12 |
Not clear |
| H Schumann, J Holtz, H R Zerkowski, M Hatzfel. Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression. Cardiovascular research. vol 45. issue 3. 2000-04-13. PMID:10728394. |
wnt genes encode secreted signaling molecules that bind to frizzled receptors and stabilize cytosolic beta-catenin which is translocated into the nucleus, acts as transcriptional activator and imparts an apoptosis resistant phenotype. |
2000-04-13 |
2023-08-12 |
human |
| I S Näthk. The adenomatous polyposis coli protein. Molecular pathology : MP. vol 52. issue 4. 2000-03-16. PMID:10694935. |
first, apc is a component of the wnt signalling pathway; second, apc may have a role in cell migration; finally, apc may regulate proliferation and apoptosis. |
2000-03-16 |
2023-08-12 |
Not clear |