| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L J Munro, L Kokkinidi. Infusion of quinpirole and muscimol into the ventral tegmental area inhibits fear-potentiated startle: implications for the role of dopamine in fear expression. Brain research. vol 746. issue 1-2. 1997-04-28. PMID:9037502. |
it was suggested that da vta neurons regulate the excitatory aspects of fear expression by gating levels of aversive emotional arousal within the amygdala-based fear system. |
1997-04-28 |
2023-08-12 |
Not clear |
| T B Borowski, L Kokkinidi. Contribution of ventral tegmental area dopamine neurons to expression of conditional fear: effects of electrical stimulation, excitotoxin lesions, and quinpirole infusion on potentiated startle in rats. Behavioral neuroscience. vol 110. issue 6. 1997-04-08. PMID:8986337. |
it was suggested that vta neurons and their forebrain da projections regulate levels of aversive emotional arousal within the amygdala-based fear system. |
1997-04-08 |
2023-08-12 |
rat |
| R Anderson, M Diotte, E Miliaressi. The bidirectional interaction between ventral tegmental rewarding and hindbrain aversive stimulation effects in the rat. Brain research. vol 688. issue 1-2. 1996-02-14. PMID:8542302. |
it was concluded that (1) the interaction between rewarding vta and aversive gi stimulation effects is bidirectional, thus suggesting the presence of algebraic summation; (2) the effect of gi on vta reward is transient whereas that of vta on gi aversion cumulates and eventually results in total abolition of gi aversion. |
1996-02-14 |
2023-08-12 |
human |
| V M Pickel, J Chan, S R Sesac. Cellular substrates for interactions between dynorphin terminals and dopamine dendrites in rat ventral tegmental area and substantia nigra. Brain research. vol 602. issue 2. 1993-04-13. PMID:8095430. |
dynorphin and other kappa opioid agonists are thought to elicit aversive actions and changes in motor activity through direct or indirect modulation of dopamine neurons in ventral tegmental area (vta) and substantia nigra (sn), respectively. |
1993-04-13 |
2023-08-12 |
mouse |
| R Bals-Kubik, A Ableitner, A Herz, T S Shippenber. Neuroanatomical sites mediating the motivational effects of opioids as mapped by the conditioned place preference paradigm in rats. The Journal of pharmacology and experimental therapeutics. vol 264. issue 1. 1993-02-23. PMID:8093731. |
the rewarding effects are associated with the activation of mu receptors in the vta, whereas aversive effects are associated with the activation of kappa receptors in the vta and its limbic-cortical terminal regions. |
1993-02-23 |
2023-08-12 |
rat |
| M M Winnicka, J J Braszko, K Wiśniewsk. Effect of angiotensin II on the passive avoidance performance in rats after bilateral 6-OHDA lesions to the hippocampus and olfactory tubercle. Polish journal of pharmacology and pharmacy. vol 41. issue 2. 1990-01-25. PMID:2512568. |
the results may suggest that dopaminergic projections from a 10 neurons of the ventral tegmental area to the dentate gyrus and olfactory tubercle are not responsible for the enhancing effect of aii on recall of passive avoidance. |
1990-01-25 |
2023-08-11 |
rat |
| W J Wilson, J C Hal. Lesions of the mesolimbic dopamine system disrupt signalled escape responses in the rat. Acta neurobiologiae experimentalis. vol 48. issue 2-3. 1988-10-20. PMID:3421151. |
classically conditioned shuttling and escape responses of 14 rats with 6-hydroxydopamine lesions of the ventral tegmental area (vta) were compared with those of 16 sham-lesioned control rats in an aversive classical conditioning paradigm. |
1988-10-20 |
2023-08-11 |
rat |
| W J Wilson, V L Tannehil. Ventral tegmental area lesions do not enhance appetitive classically conditioned responses in the rat. Acta neurobiologiae experimentalis. vol 47. issue 4. 1988-04-19. PMID:3442270. |
this lack of effect in an appetitive setting stands in contrast to our previous finding that aversive classically conditioned responses are facilitated by this lesion, and suggests that the ventral tegmental area lesion selectively enhances aversively motivated behaviors. |
1988-04-19 |
2023-08-11 |
rat |
| W J Wilson, E G Baesk. Ventral tegmental area lesions differentially affect responses controlled by CS-US contiguity and response-reinforcer contingency in the rat. Acta neurobiologiae experimentalis. vol 47. issue 2-3. 1987-12-03. PMID:3673676. |
the vta lesion increased the number of shuttle responses in the paradigms involving contiguity between a warning signal and a shock, without affecting responses controlled by the contingency between shuttling and shock avoidance. |
1987-12-03 |
2023-08-11 |
rat |
| R D Oades, J M Rivet, K Taghzouti, M Kharouby, H Simon, M Le Moa. Catecholamines and conditioned blocking: effects of ventral tegmental, septal and frontal 6-hydroxydopamine lesions in rats. Brain research. vol 406. issue 1-2. 1987-06-05. PMID:3105812. |
the performance of rats on the conditioned blocking test of learned inattention was measured in a two-way shuttle avoidance task after sham and dopamine (da)-depleting lesions of the frontal cortex, septum and ventral tegmental area (vta). |
1987-06-05 |
2023-08-11 |
rat |
| R D Oades, J M Rivet, K Taghzouti, M Kharouby, H Simon, M Le Moa. Catecholamines and conditioned blocking: effects of ventral tegmental, septal and frontal 6-hydroxydopamine lesions in rats. Brain research. vol 406. issue 1-2. 1987-06-05. PMID:3105812. |
the vta group alone showed a hyperlocomotor response to apomorphine treatment and did not acquire the avoidance response. |
1987-06-05 |
2023-08-11 |
rat |
| W A Corrigall, M A Linseman, R M D'Onofrio, H Le. An analysis of the paradoxical effect of morphine on runway speed and food consumption. Psychopharmacology. vol 89. issue 3. 1986-08-21. PMID:3088658. |
a third experiment in which morphine was microinjected into either the lateral ventricle or the ventral tegmental area supported these observations, in that intracranial morphine failed to result in an increased runway speed, but did produce taste aversion after microinjection into either site. |
1986-08-21 |
2023-08-11 |
rat |