| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yun-Bok Kim, Marguerite Matthews, Bita Moghadda. Putative γ-aminobutyric acid neurons in the ventral tegmental area have a similar pattern of plasticity as dopamine neurons during appetitive and aversive learning. The European journal of neuroscience. vol 32. issue 9. 2011-02-23. PMID:21040517. |
here we recorded from ventral tegmental area (vta) neurons, while exposing rats to novel stimuli that were predictive of an appetitive or aversive outcome in the same behavioral session. |
2011-02-23 |
2023-08-12 |
rat |
| Yun-Bok Kim, Marguerite Matthews, Bita Moghadda. Putative γ-aminobutyric acid neurons in the ventral tegmental area have a similar pattern of plasticity as dopamine neurons during appetitive and aversive learning. The European journal of neuroscience. vol 32. issue 9. 2011-02-23. PMID:21040517. |
the response of vta neurons, regardless of whether they had putative dopamine or gaba waveforms, transformed flexibly as animals learned to associate novel stimuli from different sensory modalities to appetitive or aversive outcomes. |
2011-02-23 |
2023-08-12 |
rat |
| Yun-Bok Kim, Marguerite Matthews, Bita Moghadda. Putative γ-aminobutyric acid neurons in the ventral tegmental area have a similar pattern of plasticity as dopamine neurons during appetitive and aversive learning. The European journal of neuroscience. vol 32. issue 9. 2011-02-23. PMID:21040517. |
learning the appetitive association led to larger excitatory vta responses, whereas acquiring the aversive association led to a biphasic response of brief excitation followed by sustained inhibition. |
2011-02-23 |
2023-08-12 |
rat |
| Yun-Bok Kim, Marguerite Matthews, Bita Moghadda. Putative γ-aminobutyric acid neurons in the ventral tegmental area have a similar pattern of plasticity as dopamine neurons during appetitive and aversive learning. The European journal of neuroscience. vol 32. issue 9. 2011-02-23. PMID:21040517. |
these data suggest that vta neurons interface sensory information with representational memory of aversive and appetitive events. |
2011-02-23 |
2023-08-12 |
rat |
| Mark A Ungless, Emanuela Argilli, Antonello Bonc. Effects of stress and aversion on dopamine neurons: implications for addiction. Neuroscience and biobehavioral reviews. vol 35. issue 2. 2011-02-17. PMID:20438754. |
in this review we focus our attention on recent advances made in understanding how stress, aversive events, and drugs of abuse, cocaine in particular, interact directly with dopamine neurons in the ventral tegmental area, and how these interactions may be involved in stress-induced relapse. |
2011-02-17 |
2023-08-12 |
Not clear |
| Gelavij Mahmoodi, Shamseddin Ahmadi, Ali Pourmotabbed, Shahrbanoo Oryan, Mohammad Reza Zarrindas. Inhibitory avoidance memory deficit induced by scopolamine: Interaction of cholinergic and glutamatergic systems in the ventral tegmental area. Neurobiology of learning and memory. vol 94. issue 1. 2010-09-29. PMID:20403448. |
inhibitory avoidance memory deficit induced by scopolamine: interaction of cholinergic and glutamatergic systems in the ventral tegmental area. |
2010-09-29 |
2023-08-12 |
rat |
| Jason Shumake, Anton Ilango, Henning Scheich, Wolfram Wetzel, Frank W Oh. Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 17. 2010-05-24. PMID:20427648. |
during the acquisition phase, vta stimulation improved avoidance performance, while lhb stimulation impaired it. |
2010-05-24 |
2023-08-12 |
Not clear |
| Jason Shumake, Anton Ilango, Henning Scheich, Wolfram Wetzel, Frank W Oh. Differential neuromodulation of acquisition and retrieval of avoidance learning by the lateral habenula and ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 17. 2010-05-24. PMID:20427648. |
vta stimulation appeared to improve both acquisition and asymptotic performance of the avoidance response, as vta-stimulated animals reached above-normal performance but reverted to normal responding when stimulation was discontinued. |
2010-05-24 |
2023-08-12 |
Not clear |
| Stephanie L Borgland, Shao-Ju Chang, M Scott Bowers, Jennifer L Thompson, Nicole Vittoz, Stan B Floresco, Jonathan Chou, Billy T Chen, Antonello Bonc. Orexin A/hypocretin-1 selectively promotes motivation for positive reinforcers. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 36. 2009-09-28. PMID:19741128. |
finally, oxa/hcrt-1-mediated excitatory synaptic transmission onto vta neurons was not potentiated following an arousing, aversive stimulus, suggesting that oxa/hcrt-1-mediated glutamatergic synaptic transmission was potentiated selectively with highly salient positive reinforcers. |
2009-09-28 |
2023-08-12 |
rat |
| Matthew R Campioni, Ming Xu, Daniel S McGehe. Stress-induced changes in nucleus accumbens glutamate synaptic plasticity. Journal of neurophysiology. vol 101. issue 6. 2009-08-03. PMID:19357347. |
stress hormones released in the cns following exposure to unavoidable, aversive stimuli have been shown to alter the physiology of neurons in multiple brain regions including hippocampus, amygdala, prefrontal cortex, and ventral tegmental area. |
2009-08-03 |
2023-08-12 |
mouse |
| Thomas C Jhou, Stefanie Geisler, Michela Marinelli, Beth A Degarmo, Daniel S Zah. The mesopontine rostromedial tegmental nucleus: A structure targeted by the lateral habenula that projects to the ventral tegmental area of Tsai and substantia nigra compacta. The Journal of comparative neurology. vol 513. issue 6. 2009-04-27. PMID:19235216. |
prior studies revealed that aversive stimuli and psychostimulant drugs elicit fos expression in neurons clustered above and behind the interpeduncular nucleus that project strongly to the ventral tegmental area (vta) and substantia nigra (sn) compacta (c). |
2009-04-27 |
2023-08-12 |
Not clear |
| Matthew T C Brown, Pablo Henny, J Paul Bolam, Peter J Magil. Activity of neurochemically heterogeneous dopaminergic neurons in the substantia nigra during spontaneous and driven changes in brain state. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 29. issue 9. 2009-04-10. PMID:19261887. |
furthermore, the firing of dopaminergic sn neurons is brain state-dependent, and, unlike dopaminergic vta neurons, they are not commonly recruited or inhibited by aversive stimuli. |
2009-04-10 |
2023-08-12 |
rat |
| Zhong-Hua Liu, Rick Shin, Satoshi Ikemot. Dual role of medial A10 dopamine neurons in affective encoding. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 12. 2009-02-20. PMID:18256592. |
microinjections of quinpirole into the posteromedial ventral tegmental area, but not its more lateral counterparts, led to conditioned place aversion. |
2009-02-20 |
2023-08-12 |
Not clear |
| Sergio D Iñiguez, Brandon L Warren, Rachael L Neve, Eric J Nestler, Scott J Russo, Carlos A Bolaños-Guzmá. Insulin receptor substrate-2 in the ventral tegmental area regulates behavioral responses to cocaine. Behavioral neuroscience. vol 122. issue 5. 2009-02-03. PMID:18823173. |
using viral-mediated gene transfer to locally alter the activity of irs-2, the authors show that overexpression of irs-2 in the vta results in an enhanced preference for environments previously paired with cocaine, as measured by the place conditioning paradigm, whereas blockade of irs-2 activity results in avoidance of cocaine-paired compartments. |
2009-02-03 |
2023-08-12 |
Not clear |
| Marco Diana, Alessandra Tiziana Peana, Donatella Sirca, Alessandra Lintas, Miriam Melis, Paolo Enric. Crucial role of acetaldehyde in alcohol activation of the mesolimbic dopamine system. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991876. |
additionally, these observations suggest that acd, by increasing vta da neuronal activity, would oppose its well-known peripherally originating aversive properties. |
2008-12-09 |
2023-08-12 |
Not clear |
| M Melis, P Enrico, A T Peana, M Dian. Acetaldehyde mediates alcohol activation of the mesolimbic dopamine system. The European journal of neuroscience. vol 26. issue 10. 2008-02-25. PMID:18001279. |
additionally, these observations suggest that acd, by increasing vta da neuronal activity, would oppose its well-known peripherally originating aversive properties. |
2008-02-25 |
2023-08-12 |
rat |
| Shamseddin Ahmadi, Mohammad Reza Zarrindast, Maryam Nouri, Ali Haeri-Rohani, Ameneh Rezayo. N-Methyl-D-aspartate receptors in the ventral tegmental area are involved in retrieval of inhibitory avoidance memory by nicotine. Neurobiology of learning and memory. vol 88. issue 3. 2007-11-09. PMID:17707662. |
n-methyl-d-aspartate receptors in the ventral tegmental area are involved in retrieval of inhibitory avoidance memory by nicotine. |
2007-11-09 |
2023-08-12 |
rat |
| Ameneh Rezayof, Farzaneh Nazari-Serenjeh, Mohammad-Reza Zarrindast, Houri Sepehri, Ladan Delph. Morphine-induced place preference: involvement of cholinergic receptors of the ventral tegmental area. European journal of pharmacology. vol 562. issue 1-2. 2007-06-13. PMID:17336285. |
the injection of physostigmine, but not atropine, nicotine or mecamylamine, into the ventral tegmental area alone produced a significant place aversion. |
2007-06-13 |
2023-08-12 |
rat |
| Mohammad-Reza Zarrindast, Zahra Farajzadeh, Parvin Rostami, Ameneh Rezayof, Parvaneh Nourja. Involvement of the ventral tegmental area (VTA) in morphine-induced memory retention in morphine-sensitized rats. Behavioural brain research. vol 163. issue 1. 2005-12-07. PMID:15913802. |
in the present study, the effects of intra-ventral tegmental area (vta) injections of morphine on memory retention of a one-trial passive avoidance task have been investigated in morphine-sensitized rats. |
2005-12-07 |
2023-08-12 |
rat |
| Anita J Bechtholt, Christina M Gremel, Christopher L Cunningha. Handling blocks expression of conditioned place aversion but not conditioned place preference produced by ethanol in mice. Pharmacology, biochemistry, and behavior. vol 79. issue 4. 2005-04-29. PMID:15582682. |
we attempted to determine whether vta opioid receptors also mediate the expression of the conditioned aversive properties of ethanol. |
2005-04-29 |
2023-08-12 |
mouse |