| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xingyou Huang, Seok Choi, Wenhao Wu, Pawan Kumar Shahi, Jun Hyung Lee, Chansik Hong, Jae Yeoul Ju. 5-Hydroxytryptamine Enhances the Pacemaker Activity of Interstitial Cells of Cajal in Mouse Colon. International journal of molecular sciences. vol 25. issue 7. 2024-04-13. PMID:38612808. |
various agonists of the 5-ht receptor subtype were working in colonic iccs, including the 5-ht |
2024-04-13 |
2024-04-15 |
mouse |
| Christopher L Robinson, Alexandra C G Fonseca, Efemena M Diejomaoh, Ryan S D'Souza, Michael E Schatman, Vwaire Orhurhu, Trent Emeric. Scoping Review: The Role of Psychedelics in the Management of Chronic Pain. Journal of pain research. vol 17. 2024-03-18. PMID:38496341. |
studies suggest that they may modulate pain processing through agonism primarily at the serotonin receptor, 5-ht |
2024-03-18 |
2024-03-20 |
Not clear |
| Megan E Castle, Meghan E Flaniga. The role of brain serotonin signaling in excessive alcohol consumption and withdrawal: A call for more research in females. Neurobiology of stress. vol 30. 2024-03-04. PMID:38433994. |
this review will discuss the current literature on the association between neurobiological adaptations in serotonin systems and aud in humans as well as the effectiveness of serotonin receptor manipulations on alcohol-related behaviors like consumption and withdrawal. |
2024-03-04 |
2024-03-06 |
Not clear |
| Megan E Castle, Meghan E Flaniga. The role of brain serotonin signaling in excessive alcohol consumption and withdrawal: A call for more research in females. Neurobiology of stress. vol 30. 2024-03-04. PMID:38433994. |
we next provide a detailed overview of brain region-specific roles for serotonin and serotonin receptor signaling in alcohol-related behaviors in preclinical animal models, highlighting the complexity of forming a cohesive model of serotonin function in aud and providing possible avenues for more effective therapeutic intervention. |
2024-03-04 |
2024-03-06 |
Not clear |
| Sheyda Shapouri, Aziz Sharifi, Ole Folkedal, Thomas W K Fraser, Marco A Vinda. Behavioral and neurophysiological effects of buspirone in healthy and depression-like state juvenile salmon. Frontiers in behavioral neuroscience. vol 18. 2024-02-27. PMID:38410095. |
furthermore, we attempted to reverse this dls-like profile through pharmacological manipulation of the serotonin (5-ht) system with buspirone, an anxiolytic medication that acts as a serotonin receptor agonist (i.e., decreases serotonergic signaling). |
2024-02-27 |
2024-03-02 |
Not clear |
| Navoda Jayakodiarachchi, Mallory A Maurer, Daniel C Schultz, Cayden J Dodd, Analisa Thompson Gray, Hyekyung P Cho, Olivier Boutaud, Carrie K Jones, Craig W Lindsley, Aaron M Bende. Evaluation of the Indazole Analogs of 5-MeO-DMT and Related Tryptamines as Serotonin Receptor 2 Agonists. ACS medicinal chemistry letters. vol 15. issue 2. 2024-02-14. PMID:38352850. |
herein, we report the synthesis and characterization of a novel set of substituted indazole-ethanamines and indazole-tetrahydropyridines as potent serotonin receptor subtype 2 (5-ht |
2024-02-14 |
2024-02-16 |
Not clear |
| O Aung, Mateus R Amorim, David Mendelowitz, Vsevolod Y Polotsk. Revisiting the Role of Serotonin in Sleep-Disordered Breathing. International journal of molecular sciences. vol 25. issue 3. 2024-02-10. PMID:38338762. |
5-ht acts on 5-ht receptor subtypes that modulate neural control of breathing and upper airway patency. |
2024-02-10 |
2024-02-12 |
Not clear |
| Chiara Elli, Alessio Novella, Luca Pasin. Serotonin syndrome: A pharmacovigilance comparative study of drugs affecting serotonin levels. European journal of clinical pharmacology. vol 80. issue 2. 2024-02-06. PMID:38032391. |
serotonin syndrome is a rare and potentially fatal adverse drug reaction caused by serotonergic drugs and is due to an increase in serotonin concentration or activation of the 5-ht receptor in the central nervous system. |
2024-02-06 |
2024-02-09 |
Not clear |
| Xia Wu, Ijaz Khan, Xiaoqi Ai, Jiliang Zhang, Haitao Shi, Ding Li, Meiling Hon. Effects of butyl paraben on behavior and molecular mechanism of Chinese striped-necked turtle (Mauremys sinensis). Aquatic toxicology (Amsterdam, Netherlands). vol 268. 2024-02-06. PMID:38320419. |
the analysis of neurotransmitter in the brain showed that 5-hydroxytryptamine (5-ht) contents in the groups of 500 and 5000 µg/l were significantly higher than the other groups, which was due to an increase in the mrna relative expression levels of the 5-ht receptor gene (5-htr), neurotransmitter transporter genes (drd4, slc6a4), and neurotransmitter synthase tryptophan hydroxylase (tph). |
2024-02-06 |
2024-02-09 |
Not clear |
| Mengmeng Shi, Emmanuel J Rupia, Pengxin Jiang, Weiqun L. Switch from fight-flight to freeze-hide: The impacts of severe stress and brain serotonin on behavioral adaptations in flatfish. Fish physiology and biochemistry. 2024-02-03. PMID:38308734. |
we found that 5-ht suppression with 5-ht synthesis inhibitor p-chlorophenylalanine (pcpa) and 5-ht receptor subtype 1a (5-ht |
2024-02-03 |
2024-02-06 |
Not clear |
| Giulia Radocchia, Massimiliano Marazzato, Karim Ben Harbi, Elena Capuzzo, Fabrizio Pantanella, Roberto De Giorgio, Matteo Guarino, Anna Costanzini, Letizia Zenzeri, Pasquale Parisi, Alessandro Ferretti, Enrico Felici, Anna Teresa Palamara, Giovanni Di Nardo, Serena Schipp. Chronic intestinal pseudo-obstruction: associations with gut microbiota and genes expression of intestinal serotonergic pathway. BMC microbiology. vol 24. issue 1. 2024-02-01. PMID:38302874. |
gut microbiota and its interplay with ens affect 5-ht synthesis, release, and the subsequent serotonin receptor activation. |
2024-02-01 |
2024-02-04 |
Not clear |
| Sara Redenšek Trampuž, Sander van Riet, Åsa Nordling, Magnus Ingelman-Sundber. Mechanisms of 5-HT receptor antagonists in the regulation of fibrosis in a 3D human liver spheroid model. Scientific reports. vol 14. issue 1. 2024-01-16. PMID:38228622. |
treatment of the spheroids with 5-ht or free fatty acids (ffa) induced fibrosis, whereas treatment of the spheroids with the 5-ht receptor antagonists ketanserin, pimavanserin, sarpogrelate, and sb269970 inhibited ffa-induced fibrosis via a reduction in stellate cell activation as determined by the expression of vimentin, tgf-β1 and col1a1 production. |
2024-01-16 |
2024-01-19 |
human |
| Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzli. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT Journal of medicinal chemistry. 2024-01-08. PMID:38190615. |
first-in-class selenium-containing potent serotonin receptor 5-ht alzheimer's disease (ad) has a complex and not-fully-understood etiology. |
2024-01-08 |
2024-01-10 |
Not clear |
| Patryk Pyka, Wawrzyniec Haberek, Małgorzata Więcek, Ewa Szymanska, Wesam Ali, Agnieszka Cios, Magdalena Jastrzębska-Więsek, Grzegorz Satała, Sabina Podlewska, Silvia Di Giacomo, Antonella Di Sotto, Sabrina Garbo, Tadeusz Karcz, Chiara Lambona, Francesco Marocco, Gniewomir Latacz, Sylwia Sudoł-Tałaj, Barbara Mordyl, Monika Głuch-Lutwin, Agata Siwek, Kinga Czarnota-Łydka, Dawid Gogola, Agnieszka Olejarz-Maciej, Natalia Wilczyńska-Zawal, Ewelina Honkisz-Orzechowska, Małgorzata Starek, Monika Dąbrowska, Katarzyna Kucwaj-Brysz, Rossella Fioravanti, Muhammad Jawad Nasim, Marius Hittinger, Anna Partyka, Anna Wesołowska, Cecilia Battistelli, Clemens Zwergel, Jadwiga Handzli. First-in-Class Selenium-Containing Potent Serotonin Receptor 5-HT Journal of medicinal chemistry. 2024-01-08. PMID:38190615. |
recently, the serotonin receptor 5-ht |
2024-01-08 |
2024-01-10 |
Not clear |
| Ivona Bečeheli, Marina Horvatiček, Maja Perić, Barbara Nikolić, Cyrielle Holuka, Marija Klasić, Marina Ivanišević, Mirta Starčević, Gernot Desoye, Dubravka Hranilović, Jonathan D Turner, Jasminka Šteful. Methylation of serotonin regulating genes in cord blood cells: association with maternal metabolic parameters and correlation with methylation in peripheral blood cells during childhood and adolescence. Clinical epigenetics. vol 16. issue 1. 2024-01-03. PMID:38172913. |
dna methylation plays a significant role in modulating the expression of genes responsible for maintaining 5-ht balance, such as 5-ht transporter (slc6a4), monoamine oxidase a (maoa), and 5-ht receptor type 2a (htr2a). |
2024-01-03 |
2024-01-06 |
human |
| Jieling Cai, Jamie Cheung, Samson W M Cheung, Karie T C Chin, Ricky W K Leung, Ronald S T Lam, Rakesh Sharma, Jensen H C Yiu, Connie W Wo. Butyrate acts as a positive allosteric modulator of serotonin transporter to decrease ileal serotonin availability. British journal of pharmacology. 2023-12-22. PMID:38129963. |
the effectiveness of serotonin receptor blocker to treat radiation therapy-induced emesis suggests the pathophysiological role of serotonin. |
2023-12-22 |
2023-12-24 |
Not clear |
| Marta Monteiro, Nuno C Pinheiro, Vikesh Samj. Serotonin Syndrome: An Emerging Reality in the Emergency Department. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021488. |
serotonin syndrome (ss) is an entity caused by interference with the serotonin metabolism and/or by medications that act as serotonin receptor agonists. |
2023-12-01 |
2023-12-07 |
Not clear |
| Pareena Sharma, Reid W Collis, Julien Thoma. Serotonin Syndrome Triggered by an Interaction Between Opioid Analgesics and Cobicistat: A Challenging Diagnostic Case Report. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022058. |
serotonin syndrome is a clinically diagnosed disorder that may occur secondary to medications that increase the release of endogenous serotonin, impair the reuptake of serotonin from the synaptic cleft, are direct serotonin receptor agonists, or increase the sensitivity of the postsynaptic serotonin receptor. |
2023-12-01 |
2023-12-07 |
Not clear |
| Marta Monteiro, Nuno C Pinheiro, Vikesh Samj. Serotonin Syndrome: An Emerging Reality in the Emergency Department. Cureus. vol 15. issue 10. 2023-12-01. PMID:38021488. |
serotonin syndrome (ss) is an entity caused by interference with the serotonin metabolism and/or by medications that act as serotonin receptor agonists. |
2023-11-29 |
2023-12-07 |
Not clear |
| Pareena Sharma, Reid W Collis, Julien Thoma. Serotonin Syndrome Triggered by an Interaction Between Opioid Analgesics and Cobicistat: A Challenging Diagnostic Case Report. Cureus. vol 15. issue 10. 2023-12-01. PMID:38022058. |
serotonin syndrome is a clinically diagnosed disorder that may occur secondary to medications that increase the release of endogenous serotonin, impair the reuptake of serotonin from the synaptic cleft, are direct serotonin receptor agonists, or increase the sensitivity of the postsynaptic serotonin receptor. |
2023-11-29 |
2023-12-07 |
Not clear |