| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hamed Alizadeh Pahlavan. Possible role of exercise therapy on depression: effector neurotransmitters as key players. Behavioural brain research. 2023-12-04. PMID:38048912. |
swimming exercise has antidepressant effects by increasing the sensitivity of serotonin 5-ht2 receptors and postsynaptic 5-ht1a receptors, increasing 5-ht and 5hiaa levels, increasing tph and serotonin, and decreasing inflammatory levels of ifn-γ and tnf-α. |
2023-12-04 |
2023-12-10 |
Not clear |
| Carles Espinós Ramírez, Anna Artigas Soler, Paula Gil Esteller, Noemí García Medina, Juan Tangarife Benjumea, María Martínez Garcí. Refractory hypotension secondary to chronic treatment with high doses of quetiapine. Revista espanola de anestesiologia y reanimacion. 2023-05-07. PMID:37150441. |
it acts on dopamine d1 and d2, histamine, and 5ht1a and 5ht2 receptors. |
2023-05-07 |
2023-08-14 |
Not clear |
| Cheng-Jie Li, Li-Ge Zhang, Lu-Bing Liu, Meng-Qi An, Li-Guo Dong, Han-Ying Gu, Yong-Ping Dai, Fen Wang, Cheng-Jie Mao, Chun-Feng Li. Inhibition of Spinal 5-HT3 Receptor and Spinal Dorsal Horn Neuronal Excitability Alleviates Hyperalgesia in a Rat Model of Parkinson's Disease. Molecular neurobiology. 2022-09-28. PMID:36168076. |
several 5-ht receptor subtypes have been confirmed to be associated with nociception in the spinal cord, such as 5-ht1a receptor, 5-ht1b receptor, 5-ht2 receptor, 5-ht3 receptor, and 5-ht7 receptor. |
2022-09-28 |
2023-08-14 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
evaluation of the hippocampal immunoreactivity of the serotonin 5-ht1a, 5-ht2 and 5-ht7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. |
2021-06-18 |
2023-08-13 |
rat |
| Miguel A Núñez-Ochoa, Gustavo A Chiprés-Tinajero, Laura Medina-Cej. Evaluation of the hippocampal immunoreactivity of the serotonin 5-HT1A, 5-HT2 and 5-HT7 receptors in a pilocarpine temporal lobe epilepsy rat model with fast ripples. Neuroreport. vol 32. issue 4. 2021-06-18. PMID:33470771. |
therefore, to gather more details about the state of the serotoninergic system in the hippocampus under an epileptogenic process, we studied the immunoreactivity of three 5-ht receptors (5-ht1a, 5-ht2 and 5-ht7) as well as the extracellular levels of 5-ht in the hippocampal tissue of epileptic rats with fr. |
2021-06-18 |
2023-08-13 |
rat |
| Hera Wu, DeVon Herr, Nancie J MacIver, Jeffrey C Rathmell, Valerie A Gerriet. CD4 T cells differentially express cellular machinery for serotonin signaling, synthesis, and metabolism. International immunopharmacology. vol 88. 2021-05-25. PMID:32866787. |
we therefore examined the serotonergic-related machinery in teff and treg and found differential expression of the serotonin transporter sert and 5-ht1a and 5-ht2 receptors. |
2021-05-25 |
2023-08-13 |
Not clear |
| Víctor Cervantes-Ramírez, Martha Canto-Bustos, Diana Aguilar-Magaña, Elsy Arlene Pérez-Padilla, José Luis Góngora-Alfaro, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Citalopram reduces glutamatergic synaptic transmission in the auditory cortex via activation of 5-HT1A receptors. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31714483. |
here, we characterize the modulation of excitatory post-synaptic currents by application of either 5-ht or agonists of 5-ht1a and 5-ht2 receptors, or by endogenous 5-ht evoked by citalopram on pyramidal neurons from layer ii/iii of rat auditory cortex. |
2020-07-31 |
2023-08-13 |
rat |
| Víctor Cervantes-Ramírez, Martha Canto-Bustos, Diana Aguilar-Magaña, Elsy Arlene Pérez-Padilla, José Luis Góngora-Alfaro, Juan Carlos Pineda, Marco Atzori, Humberto Salgad. Citalopram reduces glutamatergic synaptic transmission in the auditory cortex via activation of 5-HT1A receptors. Neuroreport. vol 30. issue 18. 2020-07-31. PMID:31714483. |
we observed that selective agonists of 5-ht1a and 5-ht2 receptors [8-oh-dpat (10 µm) and doi (10 µm), respectively] mimic the effect of 5-ht on the excitatory post-synaptic currents. |
2020-07-31 |
2023-08-13 |
rat |
| Ursin, Bjorvatn, Sommerfelt, Neckelmann, Bjørku. Studies on sleep/wake effects of serotonin reuptake inhibitors and receptor subtype involvement. Journal of sleep research. vol 1. issue 3. 2019-11-20. PMID:10607045. |
the waking increase was not blocked by the 5-ht2 antagonist ritanserin nor by the putative 5-ht1a antagonist (-)-alprenolol. |
2019-11-20 |
2023-08-12 |
rat |
| P P Fong, R Deguchi, K Kyozuk. Serotonergic Ligands Induce Spawning but not Oocyte Maturation in the Bivalve Mactra chinensis from Central Japan. The Biological bulletin. vol 191. issue 1. 2019-11-20. PMID:29220216. |
the vertebrate 5-ht2 receptor agonist alpha-methyl 5-ht and the selective 5ht1a agonist 8-oh-dpat were also effective at inducing spawning. |
2019-11-20 |
2023-08-13 |
Not clear |
| b' Ewa Poleszak, Weronika Stasiuk, Aleksandra Szopa, El\\xc5\\xbcbieta Wyska, Anna Serefko, Anna Oniszczuk, Sylwia Wo\\xc5\\x9bko, Katarzyna \\xc5\\x9awi\\xc4\\x85der, Piotr Wla\\xc5\\xb. Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Metabolic brain disease. vol 31. issue 4. 2018-01-12. PMID:26924124.' |
serotonergic lesion and experiment using the selective agonists of serotonin receptors 5-ht1a and 5-ht2 was conducted to evaluate the role of the serotonergic system in the antidepressant action of traxoprodil. |
2018-01-12 |
2023-08-13 |
mouse |
| b' Ewa Poleszak, Weronika Stasiuk, Aleksandra Szopa, El\\xc5\\xbcbieta Wyska, Anna Serefko, Anna Oniszczuk, Sylwia Wo\\xc5\\x9bko, Katarzyna \\xc5\\x9awi\\xc4\\x85der, Piotr Wla\\xc5\\xb. Traxoprodil, a selective antagonist of the NR2B subunit of the NMDA receptor, potentiates the antidepressant-like effects of certain antidepressant drugs in the forced swim test in mice. Metabolic brain disease. vol 31. issue 4. 2018-01-12. PMID:26924124.' |
the observed effect of traxoprodil is only partially associated with serotonergic system and is independent of the effect on the 5-ht1a and 5-ht2 serotonin receptors. |
2018-01-12 |
2023-08-13 |
mouse |
| C Grasso, G Li Volsi, M Barres. Serotonin modifies the spontaneous spiking activity of gracile nucleus neurons in rats: role of 5-HT1A and 5-HT2 receptors. Archives italiennes de biologie. vol 154. issue 2-3. 2017-03-15. PMID:27918061. |
serotonin modifies the spontaneous spiking activity of gracile nucleus neurons in rats: role of 5-ht1a and 5-ht2 receptors. |
2017-03-15 |
2023-08-13 |
rat |
| C Grasso, G Li Volsi, M Barres. Serotonin modifies the spontaneous spiking activity of gracile nucleus neurons in rats: role of 5-HT1A and 5-HT2 receptors. Archives italiennes de biologie. vol 154. issue 2-3. 2017-03-15. PMID:27918061. |
to ascertain the specificity of the effects induced by 5-ht, we utilized 8-hydroxy-2-(di-n-propylamino) tetralin (8-oh-dpat) and alpha-methyl-5-hydroxytryptamine (α-met-5-ht), agonists for 5-ht1a and 5-ht2 receptors, respectively. |
2017-03-15 |
2023-08-13 |
rat |
| C Grasso, G Li Volsi, M Barres. Serotonin modifies the spontaneous spiking activity of gracile nucleus neurons in rats: role of 5-HT1A and 5-HT2 receptors. Archives italiennes de biologie. vol 154. issue 2-3. 2017-03-15. PMID:27918061. |
these results indicate that 5-ht is able to modulate the background firing activity of gn neurons by 5-ht1a and 5-ht2 receptors. |
2017-03-15 |
2023-08-13 |
rat |
| Aram Rasul, Husameldin El-Nour, Sol-Britt Lonne-Rahm, Oscar Fransson, Charlotta Johansson, Björn Johansson, Marwe Zubeidi, Emma Seeberg, Diana Radu Djurfeldt, Efrain C Azmitia, Klas Nordlin. Serotonergic Markers in Atopic Dermatitis. Acta dermato-venereologica. vol 96. issue 6. 2017-01-13. PMID:26831833. |
biopsies were taken from lesional and non-lesional ad skin, and investigated for expression of serotonin, its receptors 5-ht1a and 5-ht2, and serotonin transporter protein (sert), using immunohistochemistry. |
2017-01-13 |
2023-08-13 |
Not clear |
| Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology. vol 134. 2016-08-25. PMID:26455457. |
among 5-ht receptor subtypes, 5-ht1a, 5-ht2, 5-ht3 and 5-ht6 receptors play an important role in modulating extrapyramidal motor disorders. |
2016-08-25 |
2023-08-13 |
Not clear |
| Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology. vol 134. 2016-08-25. PMID:26455457. |
in addition, 5-ht1a, 5-ht2, 5-ht3, 5-ht4 and 5-ht6 receptors are implicated in modulation of cognitive impairment, mood disorders (e.g., depression and anxiety) and/or psychosis, which are frequently observed in patients with pd. |
2016-08-25 |
2023-08-13 |
Not clear |
| Yukihiro Ohno, Saki Shimizu, Kentaro Tokudome, Naofumi Kunisawa, Masashi Sas. New insight into the therapeutic role of the serotonergic system in Parkinson's disease. Progress in neurobiology. vol 134. 2016-08-25. PMID:26455457. |
all these findings emphasize the therapeutic roles of the serotonergic system in pd and stimulate new insight into novel treatments by modulating 5-ht1a and 5-ht2 receptors. |
2016-08-25 |
2023-08-13 |
Not clear |
| Karolina Pytka, Anna Partyka, Magdalena Jastrzębska-Więsek, Agata Siwek, Monika Głuch-Lutwin, Barbara Mordyl, Grzegorz Kazek, Anna Rapacz, Adrian Olczyk, Adam Gałuszka, Marian Błachuta, Anna Waszkielewicz, Henryk Marona, Jacek Sapa, Barbara Filipek, Anna Wesołowsk. Antidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal Models. PloS one. vol 10. issue 11. 2016-06-13. PMID:26554929. |
our results indicate that hbk-14 and hbk-15 possess high or moderate affinity for serotonergic 5-ht2, adrenergic α1, and dopaminergic d2 receptors as well as being full 5-ht1a and 5-ht7 receptor antagonists. |
2016-06-13 |
2023-08-13 |
mouse |