| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yukio Ago, Shigeo Nakamura, Shinsuke Arikawa, Miyuki Yata, Toshio Matsud. [Involvement of prefrontal serotonergic neurons in methamphetamine-induced behavioral sensitization]. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 28. issue 2. 2008-07-24. PMID:18516987. |
these observations suggest that the 5-ht system is a neurochemical basis for the behavioral sensitization, and imply that 5-ht1a and 5-ht2 receptors may have potential therapeutic values in the remission of methamphetamine abuse or psychosis. |
2008-07-24 |
2023-08-12 |
mouse |
| Liesbeth A Bruins Slot, Laurent Bardin, Agnès L Auclair, Ronan Depoortere, Adrian Newman-Tancred. Effects of antipsychotics and reference monoaminergic ligands on marble burying behavior in mice. Behavioural pharmacology. vol 19. issue 2. 2008-06-17. PMID:18332679. |
inhibition of marble burying behavior may result from the interplay of several receptor systems, including 5-ht2 receptor blockade, dopamine d2 partial agonism and serotonin 5-ht1a agonism. |
2008-06-17 |
2023-08-12 |
mouse |
| Susan J Allee, Michael R Markham, Vielka L Salazar, Philip K Stoddar. Opposing actions of 5HT1A and 5HT2-like serotonin receptors on modulations of the electric signal waveform in the electric fish Brachyhypopomus pinnicaudatus. Hormones and behavior. vol 53. issue 3. 2008-05-02. PMID:18206154. |
these results show that 5-ht exerts bi-directional control of eod modulations in b. pinnicaudatus via action at receptors similar to mammalian 5ht1a and 5ht2 receptors. |
2008-05-02 |
2023-08-12 |
Not clear |
| Inmaculada Bellido, Laureano Delange, Aurelio Gomez-Luqu. The platelet of the patients with ischemic cardiopathy and cardiac valve disease showed a reduction of 8OH-DPAT binding sites. Thrombosis research. vol 121. issue 4. 2008-04-08. PMID:17675218. |
the serotonergic receptors mainly implied in depression are 5-ht1a and 5-ht2 receptors. |
2008-04-08 |
2023-08-12 |
human |
| Simon B Eickhoff, Claudia Rottschy, Karl Zille. Laminar distribution and co-distribution of neurotransmitter receptors in early human visual cortex. Brain structure & function. vol 212. issue 3-4. 2008-02-29. PMID:17828418. |
for each receptor (glutamatergic: ampa, kainate, nmda; cholinergic: m1, m2, m3, nicotinic; gabaergic: gabaa, gabab, benzodiazepine binding-sites; adrenergic: alpha1, alpha2; serotoninergic: 5-ht1a, 5-ht2; dopaminergic: d1; adenosine: a1), density profiles extracted perpendicular to the cortical surface were compared to cyto- and myeloarchitectonic profiles sampled at corresponding cortical sites. |
2008-02-29 |
2023-08-12 |
human |
| Theodore A Slotkin, Ian T Ryde, Charlotte A Tate, Frederic J Seidle. Lasting effects of nicotine treatment and withdrawal on serotonergic systems and cell signaling in rat brain regions: separate or sequential exposure during fetal development and adulthood. Brain research bulletin. vol 73. issue 4-6. 2008-01-07. PMID:17562392. |
prenatal nicotine exposure elicited persistent suppression of 5ht1a receptors and upregulation of 5ht2 receptors, effects that were selective for males and that first emerged in young adulthood. |
2008-01-07 |
2023-08-12 |
rat |
| Ming-Chin Lu, Ming-Tsuen Hsieh, Chi-Rei Wu, Hao-Yuan Cheng, Chia-Chang Hsieh, Yao-Tung Lin, Wen-Huang Pen. Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats. Journal of ethnopharmacology. vol 112. issue 3. 2007-12-12. PMID:17572029. |
secondly, we clarified the role of cholinergic, serotonergic or gabaergic system on the ameliorating effect of emodin by using 5-ht1a receptor partial agonist, 5-ht2 receptor antagonist, gabab agonist, gabaa antagonist and muscarinic receptor antagonist. |
2007-12-12 |
2023-08-12 |
rat |
| Ming-Chin Lu, Ming-Tsuen Hsieh, Chi-Rei Wu, Hao-Yuan Cheng, Chia-Chang Hsieh, Yao-Tung Lin, Wen-Huang Pen. Ameliorating effect of emodin, a constitute of Polygonatum multiflorum, on cycloheximide-induced impairment of memory consolidation in rats. Journal of ethnopharmacology. vol 112. issue 3. 2007-12-12. PMID:17572029. |
the beneficial effect of emodin on cxm-induced memory consolidation impairment was amplified by 8-oh-dpat (5-ht1a receptor partial agonist) and ritanserin (5-ht2 receptor antagonist), but reduced by scopolamine. |
2007-12-12 |
2023-08-12 |
rat |
| A Dogrul, M Seyre. Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord. British journal of pharmacology. vol 149. issue 5. 2007-02-02. PMID:16921395. |
systemic morphine produce antinociception mediated by spinal 5-ht7, but not 5-ht1a and 5-ht2 receptors in the spinal cord. |
2007-02-02 |
2023-08-12 |
Not clear |
| Ulrich W Laengle, Anne U Trendelenburg, Rudolf Markstein, Vicente Nogues, Anne Provencher-Bollinger, Danielle Roma. GLC756 decreases TNF-alpha via an alpha2 and beta2 adrenoceptor related mechanism. Experimental eye research. vol 83. issue 5. 2006-12-22. PMID:16938291. |
the receptors on which glc756 binds (d1, d2, d4, alpha-1, alpha-2, 5-ht1a, 5-ht2c, 5-ht1d, 5-ht2 a, beta-1, and beta-2) were suggested to play a role. |
2006-12-22 |
2023-08-12 |
rat |
| Luciane H Gargaglioni, Kênia C Bícego, Tatiane B Nucci, Luiz G S Branc. Serotoninergic receptors in the anteroventral preoptic region modulate the hypoxic ventilatory response. Respiratory physiology & neurobiology. vol 153. issue 1. 2006-09-29. PMID:16310416. |
to this end, pulmonary ventilation (v(e)) of rats was measured before and after intra-avpo microinjection of methysergide (a 5-ht1 and 5-ht2 receptor antagonist), way-100635 (a 5-ht1a receptor antagonist) and sb-269970 (a 5-ht7 receptor antagonist), followed by 60 min of hypoxia exposure (7% o2). |
2006-09-29 |
2023-08-12 |
rat |
| Hyun-Sok Kim, Hyun-Jong Jang, Kwang-Hyun Cho, Sang June Hahn, Myung-Jun Kim, Shin Hee Yoon, Yang-Hyeok Jo, Myung-Suk Kim, Duck-Joo Rhi. Serotonin inhibits the induction of NMDA receptor-dependent long-term potentiation in the rat primary visual cortex. Brain research. vol 1103. issue 1. 2006-09-28. PMID:16784733. |
based on these findings, we conclude that nmdar-dependent ltp is specifically inhibited by coactivation of 5-ht1a and 5-ht2 receptors with the increase in 5-ht levels in the rat visual cortex at the end of the critical period. |
2006-09-28 |
2023-08-12 |
rat |
| Reuven Sandy. Serotonergic mechanisms in amyotrophic lateral sclerosis. The International journal of neuroscience. vol 116. issue 7. 2006-09-05. PMID:16861147. |
in fact, 5ht1a and 5ht2 receptor agonists have been shown to prevent glutamate-induced neurotoxicity in primary cortical cell cultures and the 5-ht precursor 5-hydroxytryptophan (5-htp) improved locomotor function and survival of transgenic sod1 g93a mice, an animal model of als. |
2006-09-05 |
2023-08-12 |
mouse |
| Theodore A Slotkin, Marisa L Kreider, Charlotte A Tate, Frederic J Seidle. Critical prenatal and postnatal periods for persistent effects of dexamethasone on serotonergic and dopaminergic systems. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 31. issue 5. 2006-06-06. PMID:16160705. |
across all three regimens, dex administration evoked upregulation of cerebrocortical 5ht1a and 5ht2 receptors and the presynaptic 5ht transporter, greatest for 5ht1a receptors. |
2006-06-06 |
2023-08-12 |
rat |
| W Wolfgang Fleischhacke. Aripiprazole. Expert opinion on pharmacotherapy. vol 6. issue 12. 2006-06-01. PMID:16197361. |
partial agonism of the d2 dopamine and 5ht1a serotonin receptors, and antagonism of the 5ht2 serotonin receptor are believed to be the functional basis of its therapeutic efficacy. |
2006-06-01 |
2023-08-12 |
Not clear |
| Toshihiko Katafuchi, Tetsuya Kondo, Sachiko Take, Megumu Yoshimur. Enhanced expression of brain interferon-alpha and serotonin transporter in immunologically induced fatigue in rats. The European journal of neuroscience. vol 22. issue 11. 2006-02-07. PMID:16324116. |
finally, the poly i:c-induced fatigue was attenuated by a 5-ht1a receptor agonist but not by 5-ht2, 5-ht3 or dopamine d3 agonists. |
2006-02-07 |
2023-08-12 |
rat |
| E Calama, A V Ortíz de Urbina, A Morán, M L Martín, L San Romá. Effect of 5-hydroxytryptamine on neurogenic vasoconstriction in the isolated, autoperfused hindquarters of the rat. Clinical and experimental pharmacology & physiology. vol 32. issue 10. 2006-01-05. PMID:16173953. |
the effects of 5-ht were mimicked by 5-carboxamidotryptamine (a 5-ht1 receptor agonist) and l-694 247 (a selective 5-ht1d receptor agonist), but not by 8-hydroxy-2-dipropylaminotetralin (a 5-ht1a receptor agonist), cgs-12066b (a 5-ht1b receptor agonist), alpha-methyl-5-ht (a 5-ht2 receptor agonist), 1-(3-chlorophenyl) piperazine (a 5-ht2c receptor agonist) or 1-phenylbiguanide (a 5-ht3 receptor agonist). |
2006-01-05 |
2023-08-12 |
rat |
| Filip Scheperjans, Nicola Palomero-Gallagher, Christian Grefkes, Axel Schleicher, Karl Zille. Transmitter receptors reveal segregation of cortical areas in the human superior parietal cortex: relations to visual and somatosensory regions. NeuroImage. vol 28. issue 2. 2005-12-22. PMID:16054841. |
regional distributions of ligand binding sites of 12 different neurotransmitter receptors (glutamatergic: ampa, kainate, nmda; gabaergic: gaba(a), gaba(b); cholinergic: muscarinic m2, nicotinic; adrenergic: alpha1, alpha2; serotonergic: 5-ht1a, 5-ht2; dopaminergic: d1) were studied in human postmortem brains by means of quantitative receptor autoradiography. |
2005-12-22 |
2023-08-12 |
human |
| Theodore A Slotkin, Frederic J Seidle. The alterations in CNS serotonergic mechanisms caused by neonatal chlorpyrifos exposure are permanent. Brain research. Developmental brain research. vol 158. issue 1-2. 2005-10-27. PMID:16024092. |
to determine if these changes are permanent, we administered 1 mg/kg of cpf daily to neonatal rats on postnatal days 1-4, a regimen devoid of systemic toxicity, and examined 5ht synaptic markers at 5 months of age: radioligand binding to 5ht1a and 5ht2 receptors and to the 5ht transporter. |
2005-10-27 |
2023-08-12 |
rat |
| Filip Scheperjans, Christian Grefkes, Nicola Palomero-Gallagher, Axel Schleicher, Karl Zille. Subdivisions of human parietal area 5 revealed by quantitative receptor autoradiography: a parietal region between motor, somatosensory, and cingulate cortical areas. NeuroImage. vol 25. issue 3. 2005-07-29. PMID:15808998. |
we studied the regional and laminar distributions of the binding sites of 12 different neurotransmitter receptors (glutamatergic: ampa, kainate, nmda; gabaergic: gabaa, gabab; cholinergic: muscarinic m2, nicotinic; adrenergic: alpha1, alpha2; serotoninergic: 5-ht1a, 5-ht2; dopaminergic: d1) in human postmortem brains by means of quantitative receptor autoradiography, since the structural and functional aspects of human ba 5 are widely unknown, and previous observations have demonstrated characteristic differences in receptor distribution between motor and somatosensory areas. |
2005-07-29 |
2023-08-12 |
human |