| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Justin E Aldridge, Armando Meyer, Frederic J Seidler, Theodore A Slotki. Developmental exposure to terbutaline and chlorpyrifos: pharmacotherapy of preterm labor and an environmental neurotoxicant converge on serotonergic systems in neonatal rat brain regions. Toxicology and applied pharmacology. vol 203. issue 2. 2005-04-08. PMID:15710174. |
although neither treatment affected growth or viability, each elicited similar alterations in factors that are critical to the function of the 5ht synapse: 5ht1a receptors, 5ht2 receptors, and the presynaptic 5ht transporter (5htt). |
2005-04-08 |
2023-08-12 |
human |
| B Aouizerate, C Martin-Guehl, J Tigno. [Neurobiology and pharmacotherapy of social phobia]. L'Encephale. vol 30. issue 4. 2005-03-01. PMID:15538306. |
although no abnormality in platelet serotonin transporter density has been found, patients with social phobia appear to show an enhanced sensitivity of both post-synaptic 5ht1a and 5ht2 serotonin receptor subtypes, as reflected by increased anxiety and hormonal responses to serotoninergic probes. |
2005-03-01 |
2023-08-12 |
human |
| Thomas Hussenether, Harald Hübner, Peter Gmeiner, Reinhard Troschüt. Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: synthesis and biological testing. Bioorganic & medicinal chemistry. vol 12. issue 10. 2004-12-10. PMID:15110844. |
for the most promising compounds, intrinsic activity and binding properties to serotonin 5-ht1a and 5-ht2 were also determined. |
2004-12-10 |
2023-08-12 |
Not clear |
| Vanessa de Paula Soares, Hélio Zangross. Involvement of 5-HT1A and 5-HT2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated T-maze. Brain research bulletin. vol 64. issue 2. 2004-11-29. PMID:15342106. |
involvement of 5-ht1a and 5-ht2 receptors of the dorsal periaqueductal gray in the regulation of the defensive behaviors generated by the elevated t-maze. |
2004-11-29 |
2023-08-12 |
rat |
| José L Torres-Escalante, Jaime A Barral, María D Ibarra-Villa, Azucena Pérez-Burgos, José L Góngora-Alfaro, Juan C Pined. 5-HT1A, 5-HT2, and GABAB receptors interact to modulate neurotransmitter release probability in layer 2/3 somatosensory rat cortex as evaluated by the paired pulse protocol. Journal of neuroscience research. vol 78. issue 2. 2004-11-15. PMID:15378508. |
5-ht1a, 5-ht2, and gabab receptors interact to modulate neurotransmitter release probability in layer 2/3 somatosensory rat cortex as evaluated by the paired pulse protocol. |
2004-11-15 |
2023-08-12 |
rat |
| Araceli Sánchez-Lopez, David Centurión, Erika Vázquez, Udayasankar Arulmani, Pramod R Saxena, Carlos M Villaló. Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats: correlation with 5-HT1 and putative 5-ht5A/5B receptors. British journal of pharmacology. vol 140. issue 4. 2004-11-09. PMID:14504136. |
treatment with saline or the antagonists gr 127935 (5-ht1b/1d), the combination of way 100635 (5-ht1a) plus gr 127935, ritanserin (5-ht2), tropisetron (5-ht3/4), ly215840 (5-ht7) or a cocktail of antagonists/inhibitors consisting of yohimbine (alpha2), prazosin (alpha1), ritanserin, gr 127935, way 100635 and indomethacin (cyclooxygenase), but was abolished by methiothepin (5-ht1/2/6/7 and recombinant 5-ht5a/5b). |
2004-11-09 |
2023-08-12 |
rat |
| Wen-Huang Peng, Chi-Rei Wu, Chia-Sheng Chen, Chung-Fung Chen, Zong-Chung Leu, Ming-Tsuen Hsie. Anxiolytic effect of berberine on exploratory activity of the mouse in two experimental anxiety models: interaction with drugs acting at 5-HT receptors. Life sciences. vol 75. issue 20. 2004-10-14. PMID:15350820. |
moreover, ber decreased serotonergic system activity via activation of somatodendritic 5-ht1a autoreceptors and inhibition of postsynaptic 5-ht1a and 5-ht2 receptors. |
2004-10-14 |
2023-08-12 |
mouse |
| Claudia Regina Monassi, Leda Menescal-de-Oliveir. Serotonin 5-HT2 and 5-HT1A receptors in the periaqueductal gray matter differentially modulate tonic immobility in guinea pig. Brain research. vol 1009. issue 1-2. 2004-07-12. PMID:15120594. |
serotonin 5-ht2 and 5-ht1a receptors in the periaqueductal gray matter differentially modulate tonic immobility in guinea pig. |
2004-07-12 |
2023-08-12 |
Not clear |
| David S Paterson, Richard A Belliveau, Felicia Trachtenberg, Hannah C Kinne. Differential development of 5-HT receptor and the serotonin transporter binding in the human infant medulla. The Journal of comparative neurology. vol 472. issue 2. 2004-07-01. PMID:15048689. |
tissue receptor autoradiography with 3h-lysergic acid diethylamide (3h-lsd), 3h-8-hydroxy-2-[di-n-propylamine] tetralin (3h-8-oh-dpat), and 125i-rti-55 was used to map the distribution and developmental profile of 5-ht(1a-1d) and 5-ht2 receptors, 5-ht1a receptors, and the serotonin (5-ht) transporter (sert), respectively, to nuclei with cardiorespiratory function in the human medulla from midgestation to maturity. |
2004-07-01 |
2023-08-12 |
human |
| Mary M Niblock, Hannah C Kinney, Catherine J Luce, Richard A Belliveau, James J Filian. The development of the medullary serotonergic system in the piglet. Autonomic neuroscience : basic & clinical. vol 110. issue 2. 2004-06-08. PMID:15046730. |
tritiated (3h)-lysergic acid diethylamide (lsd) binding to 5-ht1a-d and 5-ht2 receptors and 3h-8-hydroxy-2-[di-n-propylamine]tetralin (8-oh-dpat) binding to 5-ht1a receptors were used to quantify and map the distribution of these serotonin receptors between 4 and 60 postnatal days. |
2004-06-08 |
2023-08-12 |
human |
| Justin E Aldridge, Frederic J Seidler, Theodore A Slotki. Developmental exposure to chlorpyrifos elicits sex-selective alterations of serotonergic synaptic function in adulthood: critical periods and regional selectivity for effects on the serotonin transporter, receptor subtypes, and cell signaling. Environmental health perspectives. vol 112. issue 2. 2004-05-06. PMID:14754568. |
with exposure on gd9-12, cpf elicited global elevations in 5ht1a and 5ht2 receptors and in the 5ht presynaptic transporter. |
2004-05-06 |
2023-08-12 |
Not clear |
| Mounira Banasr, Micheline Hery, Richard Printemps, Annie Daszut. Serotonin-induced increases in adult cell proliferation and neurogenesis are mediated through different and common 5-HT receptor subtypes in the dentate gyrus and the subventricular zone. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 29. issue 3. 2004-04-14. PMID:14872203. |
the 5-ht1a, 5-ht1b, and 5-ht2 receptor subtypes were chosen for their implication in depression and their location in/or next to these regions. |
2004-04-14 |
2023-08-12 |
Not clear |
| Bartosz Bobula, Krzysztof Tokarski, Agnieszka Zahorodna, Grzegorz Hes. Adaptive changes in the reactivity of 5-HT1A and 5-HT2 receptors induced in rat frontal cortex by repeated imipramine and citalopram. Naunyn-Schmiedeberg's archives of pharmacology. vol 367. issue 5. 2004-03-02. PMID:12700885. |
adaptive changes in the reactivity of 5-ht1a and 5-ht2 receptors induced in rat frontal cortex by repeated imipramine and citalopram. |
2004-03-02 |
2023-08-12 |
rat |
| Justin E Aldridge, Frederic J Seidler, Armando Meyer, Indira Thillai, Theodore A Slotki. Serotonergic systems targeted by developmental exposure to chlorpyrifos: effects during different critical periods. Environmental health perspectives. vol 111. issue 14. 2004-03-02. PMID:14594624. |
exposure to cpf on gd9-12 elicited initial suppression, immediately followed by rebound elevation, of 5ht1a and 5ht2 receptors as well as the 5ht transporter, all at doses below the threshold for cholinergic hyperstimulation and the resultant systemic toxicity. |
2004-03-02 |
2023-08-12 |
Not clear |
| M Hassanain, S Bhatt, A Siege. Differential modulation of feline defensive rage behavior in the medial hypothalamus by 5-HT1A and 5-HT2 receptors. Brain research. vol 981. issue 1-2. 2003-10-03. PMID:12885442. |
differential modulation of feline defensive rage behavior in the medial hypothalamus by 5-ht1a and 5-ht2 receptors. |
2003-10-03 |
2023-08-12 |
cat |
| Jesse A May, Marsha A McLaughlin, Najam A Sharif, Mark R Hellberg, Thomas R Dea. Evaluation of the ocular hypotensive response of serotonin 5-HT1A and 5-HT2 receptor ligands in conscious ocular hypertensive cynomolgus monkeys. The Journal of pharmacology and experimental therapeutics. vol 306. issue 1. 2003-07-24. PMID:12676887. |
evaluation of the ocular hypotensive response of serotonin 5-ht1a and 5-ht2 receptor ligands in conscious ocular hypertensive cynomolgus monkeys. |
2003-07-24 |
2023-08-12 |
human |
| M Valdez, T F Burke, J G Hensle. Selective heterologous regulation of 5-HT1A receptor-stimulated 35S GTPgammaS binding in the anterior cingulate cortex as a result of 5-HT2 receptor activation. Brain research. vol 957. issue 1. 2003-03-06. PMID:12443993. |
selective heterologous regulation of 5-ht1a receptor-stimulated 35s gtpgammas binding in the anterior cingulate cortex as a result of 5-ht2 receptor activation. |
2003-03-06 |
2023-08-12 |
rat |
| N H Bhanji, H C Margolese, M Saint-Laurent, G Chouinar. Dysphoric mania induced by high-dose mirtazapine: a case for 'norepinephrine syndrome'? International clinical psychopharmacology. vol 17. issue 6. 2003-02-25. PMID:12409687. |
histamine h2 receptors are also antagonized, as are postsynaptic serotonin 5-ht2 and 5-ht3 receptors, leading to serotonergic activity primarily via 5-ht1a receptors. |
2003-02-25 |
2023-08-12 |
human |
| M Bourin, D J P David, P Jolliet, A Gardie. [Mechanism of action of antidepressants and therapeutic perspectives]. Therapie. vol 57. issue 4. 2002-12-10. PMID:12422559. |
developing drugs using innovative mechanisms such as directly acting on 5-ht receptors (5-ht1a agonists or 5-ht2 antagonists), would appear to be useful in the treatment of depression. |
2002-12-10 |
2023-08-12 |
Not clear |
| Bartosz Bobula, Agnieszka Zahorodna, Krzysztof Tokarski, Grzegorz Hes. [Use of models for spontaneous paroxysmal activity in studies of adaptive changes in serotonin receptors]. Postepy higieny i medycyny doswiadczalnej. vol 56. issue 3. 2002-11-20. PMID:12194250. |
drugs administration induce opposite adaptive changes within 5-ht2 and 5-ht1a receptors in frontal cortex as well as in 5-ht1a and 5-ht4 receptors in the hippocampus. |
2002-11-20 |
2023-08-12 |
Not clear |