| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T Couroussé, A Bacq, C Belzung, B Guiard, L Balasse, F Louis, A-M Le Guisquet, A M Gardier, A H Schinkel, B Giros, S Gautro. Brain organic cation transporter 2 controls response and vulnerability to stress and GSK3β signaling. Molecular psychiatry. vol 20. issue 7. 2016-03-24. PMID:25092247. |
in vivo pharmacology and western blot experiments argue for increased serotonin tonus as a main mechanism for impaired gsk3β signaling in oct2(-/-) mice brain during acute response to stress. |
2016-03-24 |
2023-08-13 |
mouse |
| Y Li, L S Li, X L Zhang, Y Zhang, J D Xu, J X Zh. An enhanced cAMP pathway is responsible for the colonic hyper-secretory response to 5-HT in acute stress rats. Physiological research. vol 64. issue 3. 2016-03-07. PMID:25536313. |
in the present study, we have investigated the effects of 5-ht on rat colonic mucosal secretion after acute water immersion restraint stress, as well as the underlying mechanism of this phenomenon, using short circuit current recording (i(sc)), real-time polymerase chain reaction, western blot analysis, and enzyme-linked immunosorbance assays. |
2016-03-07 |
2023-08-13 |
rat |
| Lingpeng Zhu, Tingting Wei, Jing Gao, Xiayun Chang, He He, Mingxing Miao, Tianhua Ya. Salidroside attenuates lipopolysaccharide (LPS) induced serum cytokines and depressive-like behavior in mice. Neuroscience letters. vol 606. 2016-03-01. PMID:26300543. |
levels of neurotransmitters like norepinephrine (ne) and 5-hydroxytryptamine (5-ht) in the prefrontal cortex were detected by hplc-ms. further, brain-derived neurotrophic factor (bdnf), tropomyosin-related kinase b (trkb) and nuclear factor-κb (nf-κb) in hippocampal was determined by western blot analysis. |
2016-03-01 |
2023-08-13 |
mouse |
| Y Yang, X Cui, Y Chen, Y Wang, X Li, L Lin, H Zhan. Exendin-4, an analogue of glucagon-like peptide-1, attenuates hyperalgesia through serotonergic pathways in rats with neonatal colonic sensitivity. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 65. issue 3. 2015-04-22. PMID:24930506. |
the expressions of serotonin transporter (sert) and tryptophan hydroxylase-1 (tph-1) in colonic tissues were detected by rt-pcr and western blot, respectively. |
2015-04-22 |
2023-08-13 |
rat |
| C Lanteri, E L Doucet, S J Hernández Vallejo, G Godeheu, A-C Bobadilla, L Salomon, L Lanfumey, J-P Tassi. Repeated exposure to MDMA triggers long-term plasticity of noradrenergic and serotonergic neurons. Molecular psychiatry. vol 19. issue 7. 2015-04-15. PMID:23958955. |
finally, molecular analysis including radiolabeling, western blot and quantitative reverse transcription-polymerase chain reaction reveals that mice repeatedly treated with mdma exhibit normal α(2a)-adrenergic and 5-ht(1a) receptor binding, but a long-lasting downregulation of gαi proteins expression in both locus coeruleus and dorsal raphe nucleus. |
2015-04-15 |
2023-08-12 |
mouse |
| Zhang Tianzhu, Yang Shihai, Du Jua. Antidepressant-like effects of cordycepin in a mice model of chronic unpredictable mild stress. Evidence-based complementary and alternative medicine : eCAM. vol 2014. 2015-01-14. PMID:25587342. |
then the serotonin (5-ht) and noradrenaline (ne) concentrations in hippocampal were evaluated by hplc; tumor necrosis factor-α (tnf-α) and interleukin-6 (il-6) in hippocampal were evaluated, and the proteins of tnf-α, il-6, nf-κbp65 5-ht2a receptor (5-ht2ar), and brain-derived neurotrophic factor (bdnf) in hippocampal were evaluated by western blot. |
2015-01-14 |
2023-08-13 |
mouse |
| Nobuaki Hirota, Sarah McCuaig, Michael J O'Sullivan, James G Marti. Serotonin augments smooth muscle differentiation of bone marrow stromal cells. Stem cell research. vol 12. issue 3. 2015-01-09. PMID:24595007. |
brown norway rat bmscs stimulated with serotonin had increased expression of the smooth muscle markers smooth muscle myosin heavy chain (mhc) and α actin (α-sma) by qpcr and western blot, indicating smooth muscle differentiation. |
2015-01-09 |
2023-08-12 |
rat |
| Giuseppe Musumeci, Carla Loreto, Francesca Maria Trovato, Salvatore Giunta, Rosa Imbesi, Paola Castrogiovann. Serotonin (5HT) expression in rat pups treated with high-tryptophan diet during fetal and early postnatal development. Acta histochemica. vol 116. issue 2. 2014-12-10. PMID:24071520. |
we also analyzed by means of immunohistochemistry and western blot the expression of serotonin in rat gastric tissue and the morphological structure of skeletal muscle tissue of both control and experimental pups. |
2014-12-10 |
2023-08-12 |
human |
| Yang Bai, Han-Ming Wang, Ming Liu, Yun Wang, Guo-Chao Lian, Xin-Hua Zhang, Jian Kang, Huai-Liang Wan. 4-Chloro-DL-phenylalanine protects against monocrotaline‑induced pulmonary vascular remodeling and lung inflammation. International journal of molecular medicine. vol 33. issue 2. 2014-09-18. PMID:24337018. |
the levels of tph-1 and serotonin transporter (sert) in the lungs were analyzed by immunohistochemistry and western blot analysis. |
2014-09-18 |
2023-08-12 |
rat |
| Chi Yan, Liu Xin-Guang, Wang Hua-Hong, Li Jun-Xia, Li Yi-Xua. Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas. vol 45. issue 10. 2014-07-13. PMID:22832600. |
the 5-ht(4) receptor and sert expression of the ascending colon were monitored using immunohistochemistry and western blot analyses; the plasma 5-ht levels were measured using an elisa method. |
2014-07-13 |
2023-08-12 |
rat |
| Subha Bhaskaran, Jeremy Zaluski, Amy Banes-Bercel. Molecular interactions of serotonin (5-HT) and endothelin-1 in vascular smooth muscle cells: in vitro and ex vivo analyses. American journal of physiology. Cell physiology. vol 306. issue 2. 2014-03-14. PMID:24196534. |
with the use of rat vsmc and western blot analysis, our data suggest no effect of acute (30 min) preincubation with 5-ht (10(-9) m) and/or et-1 (10(-9) m) on the activation of either pathway in normal or high glucose conditions. |
2014-03-14 |
2023-08-12 |
rat |
| Hong-Mei Jia, Yu-Fei Feng, Yue-Tao Liu, Xing Chang, Lin Chen, Hong-Wu Zhang, Gang Ding, Zhong-Mei Zo. Integration of ¹H NMR and UPLC-Q-TOF/MS for a comprehensive urinary metabonomics study on a rat model of depression induced by chronic unpredictable mild stress. PloS one. vol 8. issue 5. 2014-02-18. PMID:23696839. |
moreover, the results of western blot analysis of aromatic l-amino acid decarboxylase (ddc) and indoleamine 2, 3-dioxygenase (ido) in the hippocampus of cums-treated rats indicated that depletion of 5-ht and tryptophan, production of 5-mt and altered expression of ddc and ido together played a key role in the initiation and progression of depression. |
2014-02-18 |
2023-08-12 |
rat |
| Ricardo Valladares, Lora Bojilova, Anastasia H Potts, Evan Cameron, Christopher Gardner, Graciela Lorca, Claudio F Gonzale. Lactobacillus johnsonii inhibits indoleamine 2,3-dioxygenase and alters tryptophan metabolite levels in BioBreeding rats. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 4. 2013-06-17. PMID:23303207. |
tissue ido was investigated using quantitative rt-pcr and western blot, whereas tryptophan, kynurenine, and 5-hydroxytryptamine (5-ht) concentrations were quantified by hplc and elisa. |
2013-06-17 |
2023-08-12 |
rat |
| Francisco Jiménez-Trejo, Miguel Tapia-Rodríguez, Marco Cerbón, Donald M Kuhn, Gabriel Manjarrez-Gutiérrez, C Adriana Mendoza-Rodríguez, Ofir Picaz. Evidence of 5-HT components in human sperm: implications for protein tyrosine phosphorylation and the physiology of motility. Reproduction (Cambridge, England). vol 144. issue 6. 2013-04-26. PMID:23028123. |
we used both immunocytochemistry and western blot to detect serotoninergic markers such as 5-ht, tph1, mao(a), 5-ht(1b), 5-ht(3), and 5ht(t); hplc for tph enzymatic activity; computer assisted semen analysis assays to measure sperm motility parameters and pharmacological approaches to show the effect of 5-ht in sperm motility and tyrosine phosphorylation was assessed by western blot. |
2013-04-26 |
2023-08-12 |
human |
| Martin Haugen, Rikard Dammen, Bernhard Svejda, Bjorn I Gustafsson, Roswitha Pfragner, Irvin Modlin, Mark Kid. Differential signal pathway activation and 5-HT function: the role of gut enterochromaffin cells as oxygen sensors. American journal of physiology. Gastrointestinal and liver physiology. vol 303. issue 10. 2013-01-15. PMID:22936271. |
isolated normal ec cells as well as the well-characterized ec cell model krj-i were used to examine hif signaling (luciferase-assays), hypoxia transcriptional response element (hre)-mediated transcription (pcr), signaling pathways (western blot), and 5-ht release (elisa) during exposure to different oxygen levels. |
2013-01-15 |
2023-08-12 |
Not clear |
| R L Bertrand, S Senadheera, A Tanoto, K L Tan, L Howitt, H Chen, T V Murphy, S L Sandow, L Liu, P P Bertran. Serotonin availability in rat colon is reduced during a Western diet model of obesity. American journal of physiology. Gastrointestinal and liver physiology. vol 303. issue 3. 2012-10-11. PMID:22595993. |
fluoxetine was used to block the 5-ht reuptake transporter (sert), and the levels of mrna for tryptophan hydroxylase 1 and sert were determined by quantitative pcr, and sert protein was determined by western blot. |
2012-10-11 |
2023-08-12 |
rat |
| Michael W McLane, Una McCann, George Ricaurt. Identifying the serotonin transporter signal in Western blot studies of the neurotoxic potential of MDMA and related drugs. Synapse (New York, N.Y.). vol 65. issue 12. 2012-07-30. PMID:21633976. |
identifying the serotonin transporter signal in western blot studies of the neurotoxic potential of mdma and related drugs. |
2012-07-30 |
2023-08-12 |
rat |
| Michael W McLane, Una McCann, George Ricaurt. Identifying the serotonin transporter signal in Western blot studies of the neurotoxic potential of MDMA and related drugs. Synapse (New York, N.Y.). vol 65. issue 12. 2012-07-30. PMID:21633976. |
a number of published studies have questioned the serotonin neurotoxic potential of 3,4-methylenedioxymethamphetamine (mdma, "ecstasy") and related drugs (fenfluramine, p-chloroamphetamine) based upon results from western blot studies using a custom synthesized serotonin transporter (sert) antibody that found no reduction in the abundance of a 50kda protein after substituted amphetamine treatment. |
2012-07-30 |
2023-08-12 |
rat |
| A Raftogianni, A Diamantopoulou, F Alikaridis, A Stamatakis, F Stylianopoulo. Effects of interaction of an early experience of reward through maternal contact or its denial with social stress during adolescence on the serotonergic system and the stress responsiveness of adult female rats. Neuroscience. vol 209. 2012-07-30. PMID:22381469. |
furthermore, in the amy of this group of animals, higher levels of 5-ht(1a) receptors were detected by western blot analysis. |
2012-07-30 |
2023-08-12 |
rat |
| Carmela M Reichel, Lauren A Ramsey, Marek Schwendt, Jacqueline F McGinty, Ronald E Se. Methamphetamine-induced changes in the object recognition memory circuit. Neuropharmacology. vol 62. issue 2. 2012-07-27. PMID:22115899. |
subsequently, transporters for serotonin (sert) and norepinephrine (net) were quantified using western blot in tissue obtained from the hippocampus, perirhinal cortex, and prefrontal cortex. |
2012-07-27 |
2023-08-12 |
human |