| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mio Doke, Takashi Matsuwaki, Keitaro Yamanouchi, Masugi Nishihar. Lack of estrogen receptor α in astrocytes of progranulin-deficient mice. The Journal of reproduction and development. vol 62. issue 6. 2017-06-06. PMID:27440553. |
first, double-labeling immunofluorescence was performed for erα with neuronal nuclei (neun), ionized calcium-binding adaptor molecule 1 (iba1), and glial fibrillary acidic protein (gfap), as markers for neurons, microglia, and astrocytes, respectively, in female mice in diestrous and estrous stages. |
2017-06-06 |
2023-08-13 |
mouse |
| Xin Yan, Liang Qiao, En-Hui Yang, Jun-Tang Li. [Activity of glial cells in the olfactory bulb of Niemann-Pick disease type C1 mice]. Sheng li xue bao : [Acta physiologica Sinica]. vol 68. issue 2. 2017-04-28. PMID:27108900. |
the results showed that npc1 gene mutation strongly increased the activation of astrocytes and microglia in olfactory bulb associated with increased protein levels of cd68 and gfap. |
2017-04-28 |
2023-08-13 |
mouse |
| Ryuji Terayama, Yuya Yamamoto, Noriko Kishimoto, Mitsuyasu Tabata, Kotaro Maruhama, Seiji Iida, Tomosada Sugimot. Differential Changes in Neuronal Excitability in the Spinal Dorsal Horn After Spinal Nerve Ligation in Rats. Neurochemical research. vol 41. issue 11. 2017-04-05. PMID:27418277. |
immunofluorescence labeling of ox-42 and gfap indicated sequential activation of microglia and astrocytes in the spinal dorsal horn. |
2017-04-05 |
2023-08-13 |
rat |
| Firas M Younis, Tamar Blumenthal-Katzir, Kenneth Hollander, Nikolaos Grigoriadis, Olga Touloumi, Roza Lagoudakic, Talma Rosentha. Telmisartan-mediated metabolic profile conferred brain protection in diabetic hypertensive rats as evidenced by magnetic resonance imaging, behavioral studies and histology. European journal of pharmacology. vol 789. 2017-03-06. PMID:27417654. |
immunohistological analysis of the brain revealed significant amelioration of diabetes/hypertension-induced changes in white matter regions and microglia, evidenced by preserved myelin (lbf marker), and improved microglial neuronal markers gfap, gap43 and iba1 expression. |
2017-03-06 |
2023-08-13 |
rat |
| Shreesh Ojha, Hayate Javed, Sheikh Azimullah, M Emdadul Haqu. β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27316720. |
further, immunohistochemical analysis revealed loss of dopaminergic neurons in the snc area and enhanced expression of ionized calcium-binding adaptor molecule-1 (iba-1) and glial fibrillary acidic protein (gfap), indicators of microglia activation, and astrocyte hypertrophy, respectively, as an index of inflammation. |
2017-02-02 |
2023-08-13 |
rat |
| Shreesh Ojha, Hayate Javed, Sheikh Azimullah, M Emdadul Haqu. β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease. Molecular and cellular biochemistry. vol 418. issue 1-2. 2017-02-02. PMID:27316720. |
however, treatment with bcp rescued dopaminergic neurons and decreased microglia and astrocyte activation evidenced by reduced iba-1 and gfap expression. |
2017-02-02 |
2023-08-13 |
rat |
| Megan M Muccigrosso, Joni Ford, Brooke Benner, Daniel Moussa, Christopher Burnsides, Ashley M Fenn, Phillip G Popovich, Jonathan Lifshitz, Fredrick Rohan Walker, Daniel S Eiferman, Jonathan P Godbou. Cognitive deficits develop 1month after diffuse brain injury and are exaggerated by microglia-associated reactivity to peripheral immune challenge. Brain, behavior, and immunity. vol 54. 2017-02-01. PMID:26774527. |
examination of mrna and morphological profiles of glia 30 dpi indicated a low but persistent level of inflammation with elevated expression of gfap and il-1β in astrocytes and mhcii and il-1β in microglia. |
2017-02-01 |
2023-08-13 |
mouse |
| Marilia Kimie Shimabukuro, Larissa Gutman Paranhos Langhi, Ingrid Cordeiro, José M Brito, Claudia Maria de Castro Batista, Mark P Mattson, Valeria de Mello Coelh. Lipid-laden cells differentially distributed in the aging brain are functionally active and correspond to distinct phenotypes. Scientific reports. vol 6. 2017-01-27. PMID:27029648. |
some cortical neun(+) neurons, gfap(+) glia limitans astrocytes, iba-1(+) microglia and s100β(+) ependymal cells expressed plin in the aging brain. |
2017-01-27 |
2023-08-13 |
mouse |
| Hao Wu, Eric V Brown, Nimish K Acharya, Denah M Appelt, Alexander Marks, Robert G Nagele, Venkat Venkatarama. Age-dependent increase of blood-brain barrier permeability and neuron-binding autoantibodies in S100B knockout mice. Brain research. vol 1637. 2017-01-24. PMID:26907191. |
these events were concurrent with compromise of neurons, increase of activated microglia and lack of astrocytic activation as evidenced by decreased expression of microtubule-associated protein type 2 (map2), elevated number of cd68 positive cells and unaltered expression of glial fibrillary acidic protein (gfap) respectively. |
2017-01-24 |
2023-08-13 |
mouse |
| Sarah V Biedermann, Johannes Fuss, Jörg Steinle, Matthias K Auer, Christof Dormann, Claudia Falfán-Melgoza, Gabriele Ende, Peter Gass, Wolfgang Weber-Fah. The hippocampus and exercise: histological correlates of MR-detected volume changes. Brain structure & function. vol 221. issue 3. 2016-12-19. PMID:25550000. |
structural mri and histological investigations concerning newborn neurons (dcx), glial cells (gfap), microglia, proliferating and pyknotic cells, neuronal activation, as well as blood vessel density and arborisation were performed. |
2016-12-19 |
2023-08-13 |
mouse |
| Patrizia Giannoni, Margarita Arango-Lievano, Ines Das Neves, Marie-Claude Rousset, Kévin Baranger, Santiago Rivera, Freddy Jeanneteau, Sylvie Claeysen, Nicola March. Cerebrovascular pathology during the progression of experimental Alzheimer's disease. Neurobiology of disease. vol 88. 2016-12-13. PMID:26774030. |
positioning of reactive iba1 microglia and gfap astrocytes at the vasculature was rendered using confocal microscopy. |
2016-12-13 |
2023-08-13 |
mouse |
| H Ueda, S K Halder, H Matsunaga, K Sasaki, S Maed. Neuroprotective impact of prothymosin alpha-derived hexapeptide against retinal ischemia-reperfusion. Neuroscience. vol 318. 2016-12-13. PMID:26779836. |
in addition, systemic post-treatment with p6q peptide significantly inhibited retinal ischemia-induced microglia and astrocyte activation in terms of increased ionized calcium-binding adaptor molecule 1 (iba-1) and glial fibrillary acidic protein (gfap) intensity, respectively, as well as their morphological changes, increased number and migration. |
2016-12-13 |
2023-08-13 |
mouse |
| Vincent Sénécal, Gabrielle Deblois, Diane Beauseigle, Raphael Schneider, Jonas Brandenburg, Jia Newcombe, Craig S Moore, Alexandre Prat, Jack Antel, Nathalie Arbou. Production of IL-27 in multiple sclerosis lesions by astrocytes and myeloid cells: Modulation of local immune responses. Glia. vol 64. issue 4. 2016-11-03. PMID:26649511. |
moreover, astrocytes (gfap(+) cells) as well as microglia and macrophages (iba1(+) cells) were important sources of il-27. |
2016-11-03 |
2023-08-13 |
human |
| Heba M Reda, Sawsan A Zaitone, Yasser M Moustaf. Effect of levetiracetam versus gabapentin on peripheral neuropathy and sciatic degeneration in streptozotocin-diabetic mice: Influence on spinal microglia and astrocytes. European journal of pharmacology. vol 771. 2016-10-24. PMID:26712375. |
in addition, levetiracetam (20 and 40mg/kg) decreased spinal immunostaining for cd11b (microglia marker) and glial fibrillary acidic protein (gfap, astrocytes marker) however; the high dose of gabapentin (40mg/kg) reduced the spinal immunostaining for gfap only. |
2016-10-24 |
2023-08-13 |
mouse |
| Diana M Norden, Paige J Trojanowski, Emmanuel Villanueva, Elisa Navarro, Jonathan P Godbou. Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge. Glia. vol 64. issue 2. 2016-10-06. PMID:26470014. |
sequential activation of microglia and astrocyte cytokine expression precedes increased iba-1 or gfap immunoreactivity following systemic immune challenge. |
2016-10-06 |
2023-08-13 |
Not clear |
| Diana M Norden, Paige J Trojanowski, Emmanuel Villanueva, Elisa Navarro, Jonathan P Godbou. Sequential activation of microglia and astrocyte cytokine expression precedes increased Iba-1 or GFAP immunoreactivity following systemic immune challenge. Glia. vol 64. issue 2. 2016-10-06. PMID:26470014. |
although proinflammatory cytokine expression in microglia peaked 2-4 h after lps, astrocyte cytokine, and chemokine induction was delayed and peaked at 12 h. morphological alterations in microglia (iba-1(+)) and astrocytes (gfap(+)), however, were undetected during this 2-12 h timeframe. |
2016-10-06 |
2023-08-13 |
Not clear |
| Hee Kyung Cho, Sang Ho Ahn, So-Yeon Kim, Mi-Jung Choi, Se Jin Hwang, Yun Woo Ch. Changes in the Expressions of Iba1 and Calcitonin Gene-Related Peptide in Adjacent Lumbar Spinal Segments after Lumbar Disc Herniation in a Rat Model. Journal of Korean medical science. vol 30. issue 12. 2016-10-06. PMID:26713069. |
immunohistochemical stainings of microglia (ionized calcium-binding adapter molecule 1; iba1), astrocytes (glial fibrillary acidic protein; gfap), calcitonin gene-related peptide (cgrp), and transient receptor potential vanilloid 1 (trpv1) was performed in spinal dorsal horns and dorsal root ganglions (drgs) at 10 days after surgery. |
2016-10-06 |
2023-08-13 |
rat |
| Meredith K Loth, Judy Choi, Jennifer L McGlothan, Mikhail V Pletnikov, Martin G Pomper, Tomás R Guilart. TSPO in a murine model of Sandhoff disease: presymptomatic marker of neurodegeneration and disease pathophysiology. Neurobiology of disease. vol 85. 2016-09-21. PMID:26545928. |
notably, tspo colocalization with the astrocyte marker gfap was greater than with the microglia marker, mac-1. |
2016-09-21 |
2023-08-13 |
mouse |
| Dong Won Kim, Jeong-Hwi Cho, Geum-Sil Cho, In Hye Kim, Joon Ha Park, Ji Hyeon Ahn, Bai Hui Chen, Bich-Na Shin, Hyun-Jin Tae, Seongkweon Hong, Jun Hwi Cho, Young-Myeong Kim, Moo-Ho Won, Jae-Chul Le. Hyperthermic preconditioning severely accelerates neuronal damage in the gerbil ischemic hippocampal dentate gyrus via decreasing SODs expressions. Journal of the neurological sciences. vol 358. issue 1-2. 2016-09-15. PMID:26365286. |
in addition, we examined the gliosis of astrocytes and microglia using anti-glial fibrillary acidic protein (gfap) and anti- ionized calcium-binding adapter molecule 1 (iba-1). |
2016-09-15 |
2023-08-13 |
Not clear |
| Qing Xin, Baohua Cheng, Yanyou Pan, Haiqing Liu, Chunqing Yang, Jing Chen, Bo Ba. Neuroprotective effects of apelin-13 on experimental ischemic stroke through suppression of inflammation. Peptides. vol 63. 2016-09-05. PMID:25278489. |
and the expression of iba1, gfap and hmgb1 in i/r rats was decreased by apelin-13 treatment indicating the inhibition of microglia, astrocytes and other inflammatory cells. |
2016-09-05 |
2023-08-13 |
rat |