| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| I Jialal, C Naidoo, B C Nathoo, M C Rajput, S M Jouber. The growth hormone responses to L-dopa and TRH in acromegaly. Journal of endocrinological investigation. vol 7. issue 3. 1984-10-11. PMID:6432894. |
the gh responses to trh and l-dopa were investigated in 14 indian and african patients with untreated acromegaly. |
1984-10-11 |
2023-08-12 |
Not clear |
| M Ishibashi, T Hara, Y Tagusagawa, T Fukushima, H Numata, T Hori, T Yamaj. Effects of ovine corticotrophin-releasing factor and hydrocortisone on growth hormone secretion by pituitary adenoma cells of acromegaly in culture. Acta endocrinologica. vol 106. issue 4. 1984-10-03. PMID:6332444. |
in an attempt to test the hypothesis that pituitary adenomas of acromegaly may possess altered cellular membrane receptors, the response of growth hormone (gh) secretion to ovine corticotrophin-releasing factor (crf) in cultured adenoma cells of acromegaly was studied. |
1984-10-03 |
2023-08-12 |
Not clear |
| M Ishibashi, T Hara, Y Tagusagawa, T Fukushima, H Numata, T Hori, T Yamaj. Effects of ovine corticotrophin-releasing factor and hydrocortisone on growth hormone secretion by pituitary adenoma cells of acromegaly in culture. Acta endocrinologica. vol 106. issue 4. 1984-10-03. PMID:6332444. |
these results suggest that crf may stimulate gh release in some, though not all, patients with acromegaly, and that glucocorticoids may block this effect of crf acting directly on the pituitary adenoma cells of acromegaly. |
1984-10-03 |
2023-08-12 |
Not clear |
| E S Penny, E Penman, J Price, L H Rees, A M Sopwith, J A Wass, N Lytras, G M Besse. Circulating growth hormone releasing factor concentrations in normal subjects and patients with acromegaly. British medical journal (Clinical research ed.). vol 289. issue 6443. 1984-10-01. PMID:6432140. |
two of the others had longstanding pituitary tumours, and the fourth patient had a pituitary growth hormone (gh) secreting tumour proved by its removal and subsequent remission of acromegaly. |
1984-10-01 |
2023-08-12 |
human |
| Y Kato, A Shimatsu, N Matsushita, H Ohta, H Imur. Role of vasoactive intestinal polypeptide (VIP) in regulating the pituitary function in man. Peptides. vol 5. issue 2. 1984-09-24. PMID:6089138. |
these findings indicate that vip may play a role in regulating prl secretion in man and may affect gh secretion from pituitary adenoma in acromegaly. |
1984-09-24 |
2023-08-12 |
human |
| J W Nortier, R J Croughs, J H Thijssen, F Schwar. Plasma growth hormone suppressive effect of bromocriptine in acromegaly. Evaluation by plasma GH day profiles and plasma GH concentrations during oral glucose tolerance tests. Clinical endocrinology. vol 20. issue 5. 1984-09-14. PMID:6744634. |
in most studies reporting favourable results of chronic bromocriptine treatment in acromegaly, plasma gh levels are measured at fixed intervals during the day. |
1984-09-14 |
2023-08-12 |
Not clear |
| J W Nortier, R J Croughs, J H Thijssen, F Schwar. Plasma growth hormone suppressive effect of bromocriptine in acromegaly. Evaluation by plasma GH day profiles and plasma GH concentrations during oral glucose tolerance tests. Clinical endocrinology. vol 20. issue 5. 1984-09-14. PMID:6744634. |
therefore, in the present report the plasma gh suppressive effect of bromocriptine in acromegaly is studied using plasma gh day-profiles as well as ogtt's during continued bromocriptine administration and ogtt's at two different time intervals after the last dose of bromocriptine. |
1984-09-14 |
2023-08-12 |
Not clear |
| A L Hulting, K Hall, S Werne. Somatomedin A increments are diminished in acromegaly with concomitant hyperprolactinaemia. Acta endocrinologica. vol 106. issue 3. 1984-08-20. PMID:6429988. |
the influence of prolactin (prl) on growth hormone (gh) regulated somatomedin a (sma) levels was studied in 30 patients with acromegaly before and after transsphenoidal pituitary surgery. |
1984-08-20 |
2023-08-12 |
Not clear |
| A L Hulting, K Hall, S Werne. Somatomedin A increments are diminished in acromegaly with concomitant hyperprolactinaemia. Acta endocrinologica. vol 106. issue 3. 1984-08-20. PMID:6429988. |
our findings offer one explanation of the lack of correlation between sma and gh levels in acromegaly. |
1984-08-20 |
2023-08-12 |
Not clear |
| K Hanew, S Sato, A Sasaki, M Kasai, Y Shimizu, O Murakami, K Yoshinag. Plasma growth hormone responses to sulpiride in patients with acromegaly. The Tohoku journal of experimental medicine. vol 142. issue 4. 1984-08-03. PMID:6429896. |
the role of endogenous dopamine (da) on plasma gh secretion was studied in 12 patients with active acromegaly. |
1984-08-03 |
2023-08-12 |
Not clear |
| K Hanew, S Sato, A Sasaki, M Kasai, Y Shimizu, O Murakami, K Yoshinag. Plasma growth hormone responses to sulpiride in patients with acromegaly. The Tohoku journal of experimental medicine. vol 142. issue 4. 1984-08-03. PMID:6429896. |
these results indicate that endogenous da has a tonic inhibitory effect on gh secretion in some cases of acromegaly, and that tumorous somatotrophs rather than elevated gh levels are the critical factor for such inhibition. |
1984-08-03 |
2023-08-12 |
Not clear |
| G Sassolas, J A Chayvialle, C Partensky, G Berger, J Trouillas, F Berger, B Claustrat, R Cohen, C Girod, R Guillemi. [Acromegaly, clinical expression of the production of growth hormone releasing factor in pancreatic tumors]. Annales d'endocrinologie. vol 44. issue 6. 1984-07-30. PMID:6430207. |
in exceptional cases, acromegaly develops as the clinical expression of an ectopic secretion of growth hormone (gh) or growth hormone-releasing factor (grf), tumorous in origin. |
1984-07-30 |
2023-08-12 |
Not clear |
| J W Nortier, R J Croughs, G H Donker, J H Thijssen, F Schwar. Changes in plasma GH levels and clinical activity during bromocriptine therapy in acromegaly. The value of predictive tests. Acta endocrinologica. vol 106. issue 2. 1984-07-17. PMID:6145276. |
changes in plasma gh levels and clinical activity during bromocriptine therapy in acromegaly. |
1984-07-17 |
2023-08-12 |
Not clear |
| K Hanew, A Sasaki, S Sato, M Kasai, Y Shimizu, O Murakami, K Yoshinag. The mechanism of postinhibitory rebound increases in plasma gh in acromegalic patients. The Tohoku journal of experimental medicine. vol 142. issue 1. 1984-06-11. PMID:6144195. |
dopamine (da) infusion (5 micrograms/kg/min for 90 min) also induced similar inhibition and postinhibitory rebound rises in gh secretion in 6 patients with acromegaly. |
1984-06-11 |
2023-08-12 |
human |
| K Hanew, A Sasaki, S Sato, M Kasai, Y Shimizu, O Murakami, K Yoshinag. The mechanism of postinhibitory rebound increases in plasma gh in acromegalic patients. The Tohoku journal of experimental medicine. vol 142. issue 1. 1984-06-11. PMID:6144195. |
all seven patients with acromegaly were trh responsive in their plasma gh (% of basal: 93.5 to 944.3). |
1984-06-11 |
2023-08-12 |
human |
| H E Carlson, S R Levin, G D Braunstein, E M Spencer, S E Wilson, J M Hershma. Effect of bromocriptine on serum hormones in acromegaly. Hormone research. vol 19. issue 3. 1984-06-08. PMID:6425186. |
these results suggest that some of the reported beneficial effects of bromocriptine in acromegaly may be independent of gh secretion or somatomedin generation. |
1984-06-08 |
2023-08-12 |
human |
| J A Was. Growth hormone neuroregulation and the clinical relevance of somatostatin. Clinics in endocrinology and metabolism. vol 12. issue 3. 1984-05-24. PMID:6142779. |
this exciting development has not only given us further insight into the control of gh secretion, but also posed interesting questions as to the cause of the abnormal gh responses to various stimuli seen in patients with acromegaly. |
1984-05-24 |
2023-08-12 |
human |
| S L Asa, B W Scheithauer, J M Bilbao, E Horvath, N Ryan, K Kovacs, R V Randall, E R Laws, W Singer, J A Linfoo. A case for hypothalamic acromegaly: a clinicopathological study of six patients with hypothalamic gangliocytomas producing growth hormone-releasing factor. The Journal of clinical endocrinology and metabolism. vol 58. issue 5. 1984-05-14. PMID:6423659. |
we report the histological, ultrastructural, and immunocytochemical features of six hypothalamic gangliocytomas associated with pituitary gh cell adenomas and/or acromegaly. |
1984-05-14 |
2023-08-12 |
human |
| S L Asa, B W Scheithauer, J M Bilbao, E Horvath, N Ryan, K Kovacs, R V Randall, E R Laws, W Singer, J A Linfoo. A case for hypothalamic acromegaly: a clinicopathological study of six patients with hypothalamic gangliocytomas producing growth hormone-releasing factor. The Journal of clinical endocrinology and metabolism. vol 58. issue 5. 1984-05-14. PMID:6423659. |
four patients had a gangliocytoma associated with pituitary gh cell adenoma and acromegaly; electron microscopy demonstrated an intimate association between neurons and adenomatous gh cells. |
1984-05-14 |
2023-08-12 |
human |
| S L Asa, B W Scheithauer, J M Bilbao, E Horvath, N Ryan, K Kovacs, R V Randall, E R Laws, W Singer, J A Linfoo. A case for hypothalamic acromegaly: a clinicopathological study of six patients with hypothalamic gangliocytomas producing growth hormone-releasing factor. The Journal of clinical endocrinology and metabolism. vol 58. issue 5. 1984-05-14. PMID:6423659. |
one patient had a gangliocytoma and a gh cell adenoma but no clinical evidence of acromegaly. |
1984-05-14 |
2023-08-12 |
human |