| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Rolandi, C Perria, V Cicchetti, A Sannia, G Magnani, C Rivano, G Michelozzi, T Barrec. Pituitary hormone concentrations in cerebrospinal fluid in patients with prolactin and growth hormone-secreting tumors. Journal of neurosurgical sciences. vol 26. issue 3. 1983-07-15. PMID:7182436. |
gh, prl, lh, fsh and tsh were measured in serum and in cerebrospinal fluid (csf) in 16 patients with chromophobe adenomas, in 8 with acromegaly and in 18 subjects with neurological diseases without endocrine troubles. |
1983-07-15 |
2023-08-12 |
human |
| E Rolandi, C Perria, V Cicchetti, A Sannia, G Magnani, C Rivano, G Michelozzi, T Barrec. Pituitary hormone concentrations in cerebrospinal fluid in patients with prolactin and growth hormone-secreting tumors. Journal of neurosurgical sciences. vol 26. issue 3. 1983-07-15. PMID:7182436. |
elevated mean gh and prl levels in serum and in csf were found in patients with chromophobe adenomas and with acromegaly. |
1983-07-15 |
2023-08-12 |
human |
| B A Lamberg, R Pelkonen, A Gordin, M Haltia, T Wahlström, A Paetau, J Leppäluot. Hyperthyroidism and acromegaly caused by a pituitary TSH- and GH-secreting tumour. Acta endocrinologica. vol 103. issue 1. 1983-07-08. PMID:6305077. |
this mixed tumour obviously secreted an excess of both gh and tsh causing acromegaly and hyperthyroidism. |
1983-07-08 |
2023-08-12 |
Not clear |
| J Cassar, M A Ghatei, D L Sarson, G F Joplin, K Mashiter, S R Bloo. Enteroglucagon and GIP after oral glucose in patients with prolactinoma and acromegaly. Clinical endocrinology. vol 18. issue 1. 1983-07-08. PMID:6342859. |
we have performed oral glucose tolerance tests (ogtt) in nine patients with prolactinomas, eight patients with active acromegaly, five patients with acromegaly in remission and nine normal controls, and measured blood glucose, plasma insulin, pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide (gip) and gh during the test. |
1983-07-08 |
2023-08-12 |
Not clear |
| M O Thorner, S M Ryan, J A Wass, A Jones, P Bouloux, S Williams, G M Besse. Effect of the dopamine agonist, lergotrile mesylate, on circulating anterior pituitary hormones in man. The Journal of clinical endocrinology and metabolism. vol 47. issue 2. 1983-06-17. PMID:45463. |
the effects of lergotrile mesylate on the serum levels of gh and prl were also studied in eight patients with acromegaly and in two with idiopathic hyperprolactinemia. |
1983-06-17 |
2023-08-11 |
human |
| M O Thorner, S M Ryan, J A Wass, A Jones, P Bouloux, S Williams, G M Besse. Effect of the dopamine agonist, lergotrile mesylate, on circulating anterior pituitary hormones in man. The Journal of clinical endocrinology and metabolism. vol 47. issue 2. 1983-06-17. PMID:45463. |
these actions are similar to those of bromocriptine (an ergot derivative treatment of hyperprolactinemia and acromegaly, to suppress prl and gh secretion, and in parkinsonism. |
1983-06-17 |
2023-08-11 |
human |
| M O Thorner, S M Ryan, J A Wass, A Jones, P Bouloux, S Williams, G M Besse. Effect of the dopamine agonist, lergotrile mesylate, on circulating anterior pituitary hormones in man. The Journal of clinical endocrinology and metabolism. vol 47. issue 2. 1983-06-17. PMID:45463. |
therefore, it may be expected that lergotrile could fulfill these clinical uses; however, in the studies comparing the effects of single oral doses of lergotrile (2 mg) and bromocriptine (2.5 mg) on gh and prl secretion in patients with acromegaly and hyperprolactinemia, lergotrile in the dose used has been found to have an earlier onset and shorter duration of action. |
1983-06-17 |
2023-08-11 |
human |
| M Ishibashi, T Yamaj. Effect of thyrotropin-releasing hormone and bromoergocriptine on growth hormone and prolactin secretion in perfused pituitary adenoma tissues of acromegaly. The Journal of clinical endocrinology and metabolism. vol 47. issue 6. 1983-06-17. PMID:122426. |
to determine the site of action of trh and 2-brom-alpha-ergocriptine (cb154) on pituitary hormone release in acromegalic patients, the effect of these substances on gh and prl secretion was examined in perfused pituitary adenoma tissues obtained at surgery from subjects with acromegaly. |
1983-06-17 |
2023-08-11 |
human |
| M Ishibashi, T Yamaj. Effect of thyrotropin-releasing hormone and bromoergocriptine on growth hormone and prolactin secretion in perfused pituitary adenoma tissues of acromegaly. The Journal of clinical endocrinology and metabolism. vol 47. issue 6. 1983-06-17. PMID:122426. |
the results suggest that both trh and cb154 possess a direct action on pituitary adenoma cells of acromegaly and that aberrant gh responses to trh and dopaminergic agonists in acromegalic patients may be explained by the altered cellular membrane receptors of the adenoma of these subjects. |
1983-06-17 |
2023-08-11 |
human |
| M Ishibashi, T Yamaji, K Kosak. Induction of growth hormone and prolactin secretion by luteinizing hormone-releasing hormone and its blockade by bromoergocriptine in acromegalic patients. The Journal of clinical endocrinology and metabolism. vol 47. issue 2. 1983-06-17. PMID:400720. |
in an attempt to evaluate the effect of lrh on gh and prl secretion, lrh in a dose of 100 micrograms was injected iv to 22 patients with active acromegaly. |
1983-06-17 |
2023-08-11 |
human |
| J C O'Keefe, S J Grant, J C Wiseman, J N Stiel, E G Wilmshurst, R A Cooper, A C Edward. Acromegaly and the heart--echocardiographic and nuclear imaging studies. Australian and New Zealand journal of medicine. vol 12. issue 6. 1983-04-07. PMID:6219656. |
thus, acromegaly is associated with increased lv mass in hypertensive patients and normotensive patients who have prolonged elevation of gh levels prior to adequate treatment. |
1983-04-07 |
2023-08-12 |
Not clear |
| P Brazeau, N Ling, P Böhlen, F Esch, S Y Ying, R Guillemi. Growth hormone releasing factor, somatocrinin, releases pituitary growth hormone in vitro. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 24. 1983-03-24. PMID:6130528. |
purified (rat) hypothalamic growth hormone releasing factor (grf), native human grf isolated from an islet cell tumor of the pancreas that had caused acromegaly, and the synthetic replicates of the human material are potent secretagogues of immunoreactive growth hormone (gh) by primary cultures of rat pituitary cells. |
1983-03-24 |
2023-08-12 |
human |
| C B Webb, J L Thominet, L A Frohma. Ectopic growth hormone releasing factor stimulates growth hormone release from human somatotroph adenomas in vitro. The Journal of clinical endocrinology and metabolism. vol 56. issue 2. 1983-03-11. PMID:6130102. |
these results 1) demonstrate for the first time e-ghrf stimulation of gh release from human pituitary tissue in vitro, 2) support an etiologic role for e-ghrf in the development of acromegaly, and 3) indicate that gh-secreting adenomas retain the capability of responding to ghrf. |
1983-03-11 |
2023-08-12 |
human |
| A L Hulting, S Werner, J Wersäll, B Tribukait, M Annik. Normal growth hormone secretion is rare after microsurgical normalization of growth hormone levels in acromegaly. Acta medica Scandinavica. vol 212. issue 6. 1983-03-11. PMID:6818841. |
the effect of microsurgery on growth hormone (gh) secretion was studied in 34 patients with acromegaly. |
1983-03-11 |
2023-08-12 |
Not clear |
| J A Wass, D R Clemmons, L E Underwood, I Barrow, G M Besser, J J Van Wy. Changes in circulating somatomedin-C levels in bromocriptine-treated acromegaly. Clinical endocrinology. vol 17. issue 4. 1983-01-27. PMID:6890417. |
the results suggest that during bromocriptine treatment of acromegaly, serum somatomedin-c concentrations correlate better with clinical status that does serum gh. |
1983-01-27 |
2023-08-12 |
Not clear |
| J A Wass, D R Clemmons, L E Underwood, I Barrow, G M Besser, J J Van Wy. Changes in circulating somatomedin-C levels in bromocriptine-treated acromegaly. Clinical endocrinology. vol 17. issue 4. 1983-01-27. PMID:6890417. |
since some patients have no significant fall in gh but show both clinical improvement and a reduction in somatomedin-c, it seems likely that in some patients bromocriptine may improve acromegaly by a mechanism other than a simple decrease in total immunoreactive gh secretion. |
1983-01-27 |
2023-08-12 |
Not clear |
| F Salerno, D Cocchi, M Lampertico, M Manneschi, G Monza, E E Mülle. Growth hormone response to thyrotropin-releasing hormone in liver cirrhosis: unique alteration in anterior pituitary responsiveness to hypothalamic hormones. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 14. issue 9. 1983-01-07. PMID:6128295. |
acromegaly, a condition in which the effect of trh escapes somatostatin suppression and lh-rh evokes gh and prl release. |
1983-01-07 |
2023-08-12 |
Not clear |
| M O Thorner, R L Perryman, M J Cronin, A D Rogol, M Draznin, A Johanson, W Vale, E Horvath, K Kovac. Somatotroph hyperplasia. Successful treatment of acromegaly by removal of a pancreatic islet tumor secreting a growth hormone-releasing factor. The Journal of clinical investigation. vol 70. issue 5. 1982-12-16. PMID:6290540. |
elevated serum gh and somatomedin c levels in a patient with an enlarged sella turcica and the characteristic responses seen in acromegaly to trh, dopamine, and glucose do not occur exclusively in patients with discrete pituitary tumors and acromegaly. |
1982-12-16 |
2023-08-12 |
rat |
| K Mashiter, L De Marco, S Van Noorden, E Adams, M Loizou, G F Joplin, T J Peter. Inappropriately low serum GH in an acromegalic: lysosomal involvement in intracellular hormone degradation. Metabolism: clinical and experimental. vol 31. issue 9. 1982-12-03. PMID:7121264. |
we conclude that the simultaneous appearance in our patient of the relatively low serum gh together with a large tumor and severe acromegaly can be explained biochemically by the striking finding of crinophagy - disposal of hormone secretory granules within the somatotroph cells themselves. |
1982-12-03 |
2023-08-12 |
Not clear |
| R Takeda, R Tatami, K Ueda, H Sagara, H Nakabayashi, H Mabuch. The incidence and pathogenesis of hyperlipidaemia in 16 consecutive acromegalic patients. Acta endocrinologica. vol 100. issue 3. 1982-10-29. PMID:7113604. |
in cases developing type iii or type v hyperlipoproteinaemia, the activity of hepatic triglyceride lipase of lipoprotien lipase was decreased, but in increased when serum gh levels fell after therapy for acromegaly. |
1982-10-29 |
2023-08-12 |
Not clear |