| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Saeed uz Zafar, R C Mellinger, G Fine, M Szabo, L A Frohma. Acromegaly associated with a bronchial carcinoid tumor: evidence for ectopic production of growth hormone-releasing activity. The Journal of clinical endocrinology and metabolism. vol 48. issue 1. 1979-05-23. PMID:422708. |
signs and symptoms of active acromegaly along with elevated gh levels persisted for 11 yr after hypophysectomy and pituitary stalk section. |
1979-05-23 |
2023-08-11 |
rat |
| K Hanew, M Aida, A Sasaki, T Mouri, K Yoshinag. Abnormal growth hormone responses to CB-154 and thyrotropin-releasing hormone (TRH) in patients with acromegaly. The Tohoku journal of experimental medicine. vol 127. issue 1. 1979-03-24. PMID:104407. |
in acromegaly, however, this agent often decreases plasma gh level paradoxically. |
1979-03-24 |
2023-08-11 |
human |
| K Hanew, M Aida, A Sasaki, T Mouri, K Yoshinag. Abnormal growth hormone responses to CB-154 and thyrotropin-releasing hormone (TRH) in patients with acromegaly. The Tohoku journal of experimental medicine. vol 127. issue 1. 1979-03-24. PMID:104407. |
in order to examine the mechanism of the so-called "paradoxical decrease" in plasma gh with cb-154, gh responses to cb-154 were compared with gh responses to thyrotropin-releasing hormone (trh), arginine, and luteinizing hormone-releasing hormone (lh-rh) in 20 cases of acromegaly. |
1979-03-24 |
2023-08-11 |
human |
| K Hanew, M Aida, A Sasaki, T Mouri, K Yoshinag. Abnormal growth hormone responses to CB-154 and thyrotropin-releasing hormone (TRH) in patients with acromegaly. The Tohoku journal of experimental medicine. vol 127. issue 1. 1979-03-24. PMID:104407. |
the value of (increase ratio of gh on trh)/(increase ratio of gh on arginine) can be used as an index for the indication of chronic cb-154 therapy in patients with acromegaly. |
1979-03-24 |
2023-08-11 |
human |
| R B Mim. Pituitary function and growth hormone dynamics in acromegaloidism. Journal of the National Medical Association. vol 70. issue 12. 1979-03-13. PMID:731719. |
these gh values and responses helped to differentiate acromegaloidism from treated and untreated acromegaly. |
1979-03-13 |
2023-08-11 |
Not clear |
| R Demura, H Yamaguchi, H Demura, K Shizum. Effect of CB-154 therapy on the glucose tolerance, IRI and GH response to glucose administration in acromegaly. Endocrinologia japonica. vol 25. issue 4. 1979-01-26. PMID:710371. |
effect of cb-154 therapy on the glucose tolerance, iri and gh response to glucose administration in acromegaly. |
1979-01-26 |
2023-08-11 |
Not clear |
| G Faglia, A Paracchi, C Ferrari, P Beck-Pecco. Evaluation of the results of trans-sphenoidal surgery in acromegaly by assessment of the growth hormone response to thyrotrophin-releasing hormone. Clinical endocrinology. vol 8. issue 5. 1978-07-26. PMID:417883. |
the present study shows that the 'paradoxical' gh responses to trh and l-dopa frequently disappear after surgery, that complete normalization of gh secretory pattern may rarely be attained, and that the disappearance of gh response to trh probably indicates satisfactory treatment of acromegaly. |
1978-07-26 |
2023-08-11 |
human |
| G Faglia, A Paracchi, C Ferrari, P Beck-Pecco. Evaluation of the results of trans-sphenoidal surgery in acromegaly by assessment of the growth hormone response to thyrotrophin-releasing hormone. Clinical endocrinology. vol 8. issue 5. 1978-07-26. PMID:417883. |
these data suggest that the 'paradoxical' gh responses frequently found in acromegaly are dependent on the adenoma per se and not on hypothalamic dysfunction. |
1978-07-26 |
2023-08-11 |
human |
| K R Schneider, G Müller, W Wiegelmann, H G Solbach, H L Krüskempe. [Comparative studies of growth hormone secretion in acromegaly after isolated and combined application of insulin hypoglycemia, LH-RH- and TRH tests (author's transl)]. Klinische Wochenschrift. vol 56. issue 9. 1978-07-24. PMID:349258. |
growth hormone (gh) release was measured in 17 patients with active acromegaly following the administration of insulin, lh-rh and trh given intravenously either combined or each separately. |
1978-07-24 |
2023-08-11 |
Not clear |
| K R Schneider, G Müller, W Wiegelmann, H G Solbach, H L Krüskempe. [Comparative studies of growth hormone secretion in acromegaly after isolated and combined application of insulin hypoglycemia, LH-RH- and TRH tests (author's transl)]. Klinische Wochenschrift. vol 56. issue 9. 1978-07-24. PMID:349258. |
inappropriate stimulation of gh release was found in 9 out of the 17 patients with acromegaly, when trh was given as the only hormone; conversely this phenomenon due to lh-rh application was observed in 4 cases. |
1978-07-24 |
2023-08-11 |
Not clear |
| K R Schneider, G Müller, W Wiegelmann, H G Solbach, H L Krüskempe. [Comparative studies of growth hormone secretion in acromegaly after isolated and combined application of insulin hypoglycemia, LH-RH- and TRH tests (author's transl)]. Klinische Wochenschrift. vol 56. issue 9. 1978-07-24. PMID:349258. |
the combined insulin-induced hypoglycemia/lh-rh/trh-test is therefore advisable for patients with acromegaly, since gh release as well as other hypophyseal partial functions can be tested. |
1978-07-24 |
2023-08-11 |
Not clear |
| S Werne. Regulation of growth hormone secretion during normal conditions and in patients with acromegaly. Acta endocrinologica. Supplementum. vol 216. 1978-06-28. PMID:274037. |
in acromegaly and gigantism, conditions characterized by chronic hypersecretion of gh, the gh producing cells are less differentiated as indicated by their response with gh release to unphysiological stimuli as well as their cessation of gh release to stimuli that normally act as releasors of gh. |
1978-06-28 |
2023-08-11 |
Not clear |
| W Saege. [Morphological classification of pituitary adenomas and its value for clinical diagnosis]. Endokrinologie. vol 71. issue 1. 1978-06-17. PMID:205406. |
95% of the cases with acromegaly based on undifferentiated acidophilic or highly differentiated gh cell adenomas. |
1978-06-17 |
2023-08-11 |
Not clear |
| E E Müller, D Cocchi, A E Panerai, I Gil-Ad, V Locatelli, P Mantegazz. Pituitary hormones and ergot alkaloids. Pharmacology. vol 16 Suppl 1. 1978-06-12. PMID:205891. |
ergolines also exert clear-cut prl-lowering effects and are capable of suppressing gh secretion in acromegaly. |
1978-06-12 |
2023-08-11 |
Not clear |
| F Silvestrini, A Liuzzi, P G Chiodin. Effect of ergot alkaloids on growth hormone and prolactin secretion in humans. Pharmacology. vol 16 Suppl 1. 1978-06-12. PMID:643905. |
physiopathological studies in the humans indicate that, according to the experimental data, bromocriptine inhibits gh release in acromegaly and prl secretion through a dopaminergic mechanism of action playing at the pituitary level. |
1978-06-12 |
2023-08-11 |
human |
| D Cocchi, A Di Giulio, A Groppetti, P Mantegazza, E E Müller, P F Span. Effect of hypophysectomy and growth hormone on tryptophan and serotonin metabolism. Acta vitaminologica et enzymologica. vol 29. issue 1-6. 1978-03-10. PMID:1244131. |
consonant with this view are the preliminary findings that in 7 individuals with elevated plasma gh levels for acromegaly, plasma tp levels were lower than in control subjects. |
1978-03-10 |
2023-08-11 |
mouse |
| J Halse, H N Haugen, T Bohme. Bromocriptine treatment in acromegaly: clinical and biochemical effects. Acta endocrinologica. vol 86. issue 3. 1977-12-29. PMID:335755. |
eight selected patients with active acromegaly and elevated gh levels without other endocrine disturbances were submitted to long-term treatment and acute dose-response trials with bromocriptine. |
1977-12-29 |
2023-08-11 |
Not clear |
| A Jannì, E Carmina, P Lanzara, R Lo Coco, R A Long. [Dynamic evaluation of GH secretion in acromegaly as a criterion for the choice of treatment]. La Clinica terapeutica. vol 82. issue 3. 1977-12-29. PMID:410583. |
[dynamic evaluation of gh secretion in acromegaly as a criterion for the choice of treatment]. |
1977-12-29 |
2023-08-11 |
Not clear |
| M F Scanlon, A Gomez-Pan, B Mora, D B Cook, J H Dewar, A Hildyard, D R Weightman, D C Evered, R Hal. Effects of nomifensine, an inhibitor of endogenous catecholamine re-uptake, in acromegaly, in hyperprolactinaemia, and against stimulated prolactin release in man. British journal of clinical pharmacology. vol 4Suppl 2. 1977-12-29. PMID:911652. |
nomifensine, an inhibitor of endogenous catecholamine re-uptake, did not affect the growth hormone (gh) or prolactin levels in patients with acromegaly or hyperprolactinaemia. |
1977-12-29 |
2023-08-11 |
Not clear |
| R Demura, O Kubo, E Odagiri, K Nomura, H Yamaguch. Growth hormone and prolactin in tissue culture of pituitary adenoma. Endocrinologia japonica. vol 24. issue 3. 1977-12-29. PMID:913336. |
pituitary adenomas obtained from 6 patients with acromegaly and 8 patients with chromophobe adenoma were subjected to the tissue culture to correlate in vitro secretion of growth hormone (gh) and prolactin (prl) to preoperative in vivo endocrine studies and endocrinilogical manifestations. |
1977-12-29 |
2023-08-11 |
Not clear |