| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Jadresic, L M Banks, D F Child, L Diamant, F H Doyle, T R Fraser, G F Jopli. The acromegaly syndrome. Relation between clinical features, growth hormone values and radiological characteristics of the pituitary tumours. The Quarterly journal of medicine. vol 51. issue 202. 1982-10-21. PMID:7111679. |
early treatment of acromegaly, particularly in young patients and those presenting with high gh values, is recommended. |
1982-10-21 |
2023-08-12 |
Not clear |
| K Kovacs, E Horvath, C Ezrin, M H Weis. Adenoma of the human pituitary producing growth hormone and thyrotropin. A histologic, immunocytologic and fine-structural study. Virchows Archiv. A, Pathological anatomy and histology. vol 395. issue 1. 1982-07-22. PMID:7080435. |
clinically, the patient had acromegaly and euthyroidism with elevated blood gh concentrations. |
1982-07-22 |
2023-08-12 |
human |
| K Kovacs, E Horvath, C Ezrin, M H Weis. Adenoma of the human pituitary producing growth hormone and thyrotropin. A histologic, immunocytologic and fine-structural study. Virchows Archiv. A, Pathological anatomy and histology. vol 395. issue 1. 1982-07-22. PMID:7080435. |
it is concluded that pituitary adenomas composed of tsh-like cells may secret gh, resulting in acromegaly. |
1982-07-22 |
2023-08-12 |
human |
| K Chihara, J Iwasaki, N Minamitani, H Kaji, S Matsukura, N Tamaki, S Matsumoto, T Fujit. Effect of vasoactive intestinal polypeptide on growth hormone secretion in perifused acromegalic pituitary adenoma tissues. The Journal of clinical endocrinology and metabolism. vol 54. issue 4. 1982-05-27. PMID:6120948. |
the effects of vasoactive intestinal polypeptide (vip), dopamine, and somatostatin (srif) on gh secretion were examined in vitro in perifused pituitary adenoma tissues obtained at surgery from seven patients with acromegaly. |
1982-05-27 |
2023-08-12 |
Not clear |
| G Delitala, M Giusti, L Borsi, L Devilla, G Mazzochi, G Lotti, G Giordan. Effects of a Met-enkephalin analogue and naloxone infusion on anterior pituitary hormone secretion in acromegaly. Hormone research. vol 15. issue 2. 1982-04-20. PMID:6276286. |
the data suggest that endogenous opiate receptors do not play a major role in modulating gh hypersecretion in acromegaly. |
1982-04-20 |
2023-08-12 |
Not clear |
| C M Feek, J S Bevan, S Taylor, N S Brown, J D Bair. The effect of bromocriptine on insulin secretion and glucose tolerance in patients with acromegaly. Clinical endocrinology. vol 15. issue 5. 1982-04-12. PMID:7035013. |
the oral administration of bromocriptine 5 mg 6-hourly to twelve patients with acromegaly for a mean period of 12 (range 3-27) months significantly reduced whole blood glucose, plasma insulin and plasma growth hormone (gh) concentrations during a 50 g oral glucose tolerance test (ogtt). |
1982-04-12 |
2023-08-12 |
Not clear |
| C M Feek, J S Bevan, S Taylor, N S Brown, J D Bair. The effect of bromocriptine on insulin secretion and glucose tolerance in patients with acromegaly. Clinical endocrinology. vol 15. issue 5. 1982-04-12. PMID:7035013. |
it is concluded that bromocriptine therapy improves glucose tolerance in acromegaly by suppressing gh secretion and consequently gh-mediated antagonism of insulin. |
1982-04-12 |
2023-08-12 |
Not clear |
| N Matsushita, Y Kato, H Katakami, A Shimatsu, N Yanaihara, H Imur. Stimulation of growth hormone release by vasoactive intestinal polypeptide from human pituitary adenomas in vitro. The Journal of clinical endocrinology and metabolism. vol 53. issue 6. 1982-01-28. PMID:6795228. |
dispersed pituitary tumor cells obtained from three patients with acromegaly were placed in a superfusion column, and the amounts of gh in the superfusate were determined. |
1982-01-28 |
2023-08-12 |
human |
| A C Moses, M E Molitch, C T Sawin, I M Jackson, B J Biller, R Furlanetto, S Reichli. Bromocriptine therapy in acromegaly: use in patients resistant to conventional therapy and effect on serum levels of somatomedin C. The Journal of clinical endocrinology and metabolism. vol 53. issue 4. 1981-12-21. PMID:6793607. |
the patterns of response to provocative stimuli of gh secretion in acromegaly were maintained during bromocriptine therapy, as has been previously been reported. |
1981-12-21 |
2023-08-12 |
Not clear |
| L D Stonesifer, R M Jordan, P O Kohle. Somatomedin C in treated acromegaly: poor correlation with growth hormone and clinical response. The Journal of clinical endocrinology and metabolism. vol 53. issue 5. 1981-12-21. PMID:7197287. |
determination of somatomedin c costs more than gh determinations and appears to offer no apparent advantage over gh in following patients treated for acromegaly. |
1981-12-21 |
2023-08-12 |
Not clear |
| L F Agnati, F Benfenati, G Frank, M Capelli, P Bernardi, L Calz. Abnormal control of growth hormone secretion by opiate systems in acromegalic patients: a study with naloxone and 2-Br-alpha-ergocryptine (CB 154). Medical biology. vol 59. issue 1. 1981-10-25. PMID:7266088. |
the latter effect deserves further study aimed at a possible new therapeutic approach to gh hypersecretion observed in acromegaly. |
1981-10-25 |
2023-08-12 |
Not clear |
| L F Agnati, F Benfenati, G Frank, M Capelli, P Bernardi, L Calz. Abnormal control of growth hormone secretion by opiate systems in acromegalic patients: a study with naloxone and 2-Br-alpha-ergocryptine (CB 154). Medical biology. vol 59. issue 1. 1981-10-25. PMID:7266088. |
naloxone also interfered with the lowering effects of cb154 and gh and prl serum levels, pointing to the existence of an interaction between dopaminergic and opiate control of gh and prl secretion in acromegaly. |
1981-10-25 |
2023-08-12 |
Not clear |
| Z Laron, A Kowadlo-Silbergeld, R Eshet, A Pertzela. Growth hormone resistance. Annals of clinical research. vol 12. issue 5. 1981-07-09. PMID:6263171. |
states of resistance to exogenous gh by receptor occupancy exist when endogenous hormone is secreted in large amounts (newborns, acromegaly) or even normal amounts. |
1981-07-09 |
2023-08-12 |
human |
| N F Lawton, A J Evans, R O Welle. Dopaminergic inhibition of growth hormone and prolactin release during continuous in vitro perifusion of normal and adenomatous human pituitary. Journal of the neurological sciences. vol 49. issue 2. 1981-06-13. PMID:7217982. |
growth hormone (gh) release in vivo is stimulated by levodopa in normal subjects but inhibited in acromegaly. |
1981-06-13 |
2023-08-12 |
human |
| N F Lawton, A J Evans, R O Welle. Dopaminergic inhibition of growth hormone and prolactin release during continuous in vitro perifusion of normal and adenomatous human pituitary. Journal of the neurological sciences. vol 49. issue 2. 1981-06-13. PMID:7217982. |
it is suggested that the paradoxical gh response to levodopa in acromegaly can be explained by a dual action of dopamine at hypothalamic and pituitary levels. |
1981-06-13 |
2023-08-12 |
human |
| S W Lamberts, M de Quijada, J G Klij. The effect of tamoxifen on GH and PRL secretion by human pituitary tumors. Journal of endocrinological investigation. vol 3. issue 4. 1981-05-21. PMID:7204884. |
in the present study pretreatment for 36 h with tamoxifen did no modify the suppressive action of bromocriptine on prl secretion in 2 patients with a prolactinoma and low plasma 17 beta-estradiol levels, while in 2 patients with acromegaly tamoxifen did not influence the lack of effect of bromocriptine on growth hormone (gh) secretion. |
1981-05-21 |
2023-08-12 |
human |
| T Naito, T Nakamura, H Suzuki, K Kasai, H Shiin. [A case of acromegaly with decreased GH levels in the serum by the treatment of either metoclopramide or the combination with CB-154 (author's transl)]. Horumon to rinsho. Clinical endocrinology. vol 28. issue 9. 1981-04-24. PMID:7460352. |
[a case of acromegaly with decreased gh levels in the serum by the treatment of either metoclopramide or the combination with cb-154 (author's transl)]. |
1981-04-24 |
2023-08-12 |
Not clear |
| R Demura, T Suda, I Wakabayashi, M Yoshimura, K Jibiki, E Odagiri, H Demura, K Shizum. Plasma pituitary hormone responses to the synthetic enkephalin analog (FK 33-824) in normal subjects and patients with pituitary diseases. The Journal of clinical endocrinology and metabolism. vol 52. issue 2. 1981-04-24. PMID:7462391. |
in patients with acromegaly, there was little or no increase in gh and prl after fk 33-824. |
1981-04-24 |
2023-08-12 |
human |
| J Trouillas, C Girod, M Lhéritier, B Claustrat, M P Duboi. Morphological and biochemical relationships in 31 human pituitary adenomas with acromegaly. Virchows Archiv. A, Pathological anatomy and histology. vol 389. issue 2. 1981-03-24. PMID:7456323. |
in 22 pure gh cell adenomas and 9 mixed gh cell-prolactin cell adenomas with acromegaly, we compare the morphological and functional data (secretory activity and granular appearance) with gh levels (radioimmunoassays) in the blood and in the tumor. |
1981-03-24 |
2023-08-12 |
human |
| R Luboshitzky, D Barzila. Bromocriptine for an acromegalic patient. Improvement in cardiac function and carpal tunnel syndrome. JAMA. vol 244. issue 16. 1980-12-18. PMID:7420685. |
bromocriptine may correct cardiac dysfunction and carpal tunnel syndrome in acromegaly either by reduction of gh oversecretion or by a direct effect of bromocriptine on dopamine receptors in the heart and peripheral nerve endings. |
1980-12-18 |
2023-08-12 |
Not clear |