| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| U Knigge, B Thuesen, F Wollesen, A Dejgaard, P M Christianse. Histamine-induced paradoxical growth hormone response to thyrotropin-releasing hormone in normal men. The Journal of clinical endocrinology and metabolism. vol 58. issue 4. 1984-04-20. PMID:6421867. |
gh responses to trh occur in patients with certain diseases, such as acromegaly, severe liver disease, uremia, and mental disorders, and presumably reflect disruption of normal hypothalamic control of gh secretion. |
1984-04-20 |
2023-08-12 |
human |
| W V Tamborlane, M Genel, S Gianfredi, J M Gertne. The effect of small but sustained elevations in circulating growth hormone on fuel metabolism in growth hormone deficiency. Pediatric research. vol 18. issue 2. 1984-04-11. PMID:6366723. |
although growth hormone (gh) concentrations are not always pathologically elevated in patients with acromegaly, it has been suggested that the metabolic and somatic consequences of this condition may be due to a loss of the normal episodic secretion of gh. |
1984-04-11 |
2023-08-12 |
Not clear |
| T Yoshida, T Hayakawa, S Mori, Y Ushio, H Nakagawa, H Mogami, Y Nakat. [Primary culture of human functioning pituitary adenoma in monolayer and collagen gel culture]. No shinkei geka. Neurological surgery. vol 11. issue 11. 1984-03-16. PMID:6664443. |
gh secretion in the culture media was initially high in all cases with acromegaly in both monolayer and collagen gel cultures. |
1984-03-16 |
2023-08-12 |
human |
| G F Pieters, A R Hermus, A G Smals, P W Kloppenbor. Paradoxical responsiveness of growth hormone to corticotropin-releasing factor in acromegaly. The Journal of clinical endocrinology and metabolism. vol 58. issue 3. 1984-03-12. PMID:6420444. |
corticotropin-releasing factor elicited an increase in serum gh in two of six patients with acromegaly. |
1984-03-12 |
2023-08-12 |
Not clear |
| M M Esiri, C B Adams, C Burke, R Underdow. Pituitary adenomas: immunohistology and ultrastructural analysis of 118 tumors. Acta neuropathologica. vol 62. issue 1-2. 1984-02-22. PMID:6318500. |
by light microscopy, using the immunoperoxidase (pap) technique, immunoreactive gh was demonstrated in all the tumours from patients with acromegaly or gigantism, immunoreactive acth in all tumours from patients with cushing's syndrome or nelson's syndrome and immunoreactive prl in 95% of tumours associated with effects of hyperprolactinaemia. |
1984-02-22 |
2023-08-12 |
Not clear |
| P Kendall-Taylor, G Upstill-Goddard, D Coo. Longterm pergolide treatment of acromegaly. Clinical endocrinology. vol 19. issue 6. 1984-02-22. PMID:6652932. |
we conclude that pergolide given once daily has a beneficial effect in acromegaly, with significant reduction in serum gh; it promises to be a useful therapeutic agent. |
1984-02-22 |
2023-08-12 |
Not clear |
| M Ishibashi, T Yamaj. Direct effects of catecholamines, thyrotropin-releasing hormone, and somatostatin on growth hormone and prolactin secretion from adenomatous and nonadenomatous human pituitary cells in culture. The Journal of clinical investigation. vol 73. issue 1. 1984-02-20. PMID:6140273. |
to determine the mechanism and the site of action of catecholamines as well as hormones including thyrotropin-releasing hormone (trh)1 and somatostatin on pituitary hormone release in patients with acromegaly and in normal subjects, the effects of these substances on growth hormone (gh) and prolactin (prl) secretion from adenomatous and nonadenomatous human pituitary cells in culture were examined. |
1984-02-20 |
2023-08-12 |
human |
| b' E Carmina, F Rosato, S Pirronello, A Jann\\xc3\\xa. Hypothalamic-pituitary-thyroid axis in acromegaly. Journal of endocrinological investigation. vol 6. issue 4. 1984-01-27. PMID:6417217.' |
hypothalamic effects of gh hyperproduction may explain the alterations of tsh secretion in many cases in view of the normalization of tsh secretion after therapy of acromegaly. |
1984-01-27 |
2023-08-12 |
Not clear |
| M Anniko, B Tribukait, J Wersäl. Human pituitary tumors with two cell lines. Archives of oto-rhino-laryngology. vol 238. issue 3. 1984-01-27. PMID:6651609. |
the latter were found in tumors causing acromegaly either with secretion of growth hormone (gh) alone (n = 2) or in combination with prolactin (prl) (n = 3). |
1984-01-27 |
2023-08-12 |
human |
| K Chihara, H Kaji, N Minamitani, H Kodama, T Kita, B Goto, T Chiba, D H Coy, T Fujit. Stimulation of growth hormone by vasoactive intestinal polypeptide in acromegaly. The Journal of clinical endocrinology and metabolism. vol 58. issue 1. 1984-01-26. PMID:6417157. |
on the other hand, plasma gh levels rose markedly after vip injection in all 6 patients with untreated acromegaly. |
1984-01-26 |
2023-08-12 |
human |
| K Chihara, H Kaji, N Minamitani, H Kodama, T Kita, B Goto, T Chiba, D H Coy, T Fujit. Stimulation of growth hormone by vasoactive intestinal polypeptide in acromegaly. The Journal of clinical endocrinology and metabolism. vol 58. issue 1. 1984-01-26. PMID:6417157. |
in 2 other patients with inactive acromegaly as well as in normal subjects, vip failed to affect plasma gh levels. |
1984-01-26 |
2023-08-12 |
human |
| K Chihara, H Kaji, N Minamitani, H Kodama, T Kita, B Goto, T Chiba, D H Coy, T Fujit. Stimulation of growth hormone by vasoactive intestinal polypeptide in acromegaly. The Journal of clinical endocrinology and metabolism. vol 58. issue 1. 1984-01-26. PMID:6417157. |
in all 6 patients with active acromegaly, lrh (1-2 micrograms/kg bw, iv) did not increase plasma gh levels, but trh (5-10 micrograms/kg bw, iv) caused significant increases in plasma gh, the magnitude of which was not similar to that of increases seen after vip injection. |
1984-01-26 |
2023-08-12 |
human |
| J E Eigenmann, R Y Eigenmann, A Rijnberk, I van der Gaag, J Zapf, E R Froesc. Progesterone-controlled growth hormone overproduction and naturally occurring canine diabetes and acromegaly. Acta endocrinologica. vol 104. issue 2. 1983-12-17. PMID:6227190. |
acromegaly associated soft tissue changes were also reversible after mpa withdrawal and/or ovx-hyx when gh levels had dropped. |
1983-12-17 |
2023-08-12 |
Not clear |
| S Melmed, G D Braunstein, E Horvath, C Ezrin, K Kovac. Pathophysiology of acromegaly. Endocrine reviews. vol 4. issue 3. 1983-12-17. PMID:6354702. |
extrapituitary causes of acromegaly include eutopic gh cell adenoma in the sphenoid sinus or parapharyngeal region and excess ghrf secretion which may be eutopic or ectopic. |
1983-12-17 |
2023-08-12 |
Not clear |
| S Melmed, G D Braunstein, E Horvath, C Ezrin, K Kovac. Pathophysiology of acromegaly. Endocrine reviews. vol 4. issue 3. 1983-12-17. PMID:6354702. |
finally, a multistage theory of gh cell tumorigenesis has been proposed as a model in an attempt to unify the genetic, environmental and biochemical factors implicated in the pathogenesis of acromegaly. |
1983-12-17 |
2023-08-12 |
Not clear |
| M Arosio, M A Giovanelli, E Riva, C Nava, B Ambrosi, G Fagli. Clinical use of pre- and postsurgical evaluation of abnormal GH responses in acromegaly. Journal of neurosurgery. vol 59. issue 3. 1983-10-08. PMID:6411870. |
clinical use of pre- and postsurgical evaluation of abnormal gh responses in acromegaly. |
1983-10-08 |
2023-08-12 |
Not clear |
| M Arosio, M A Giovanelli, E Riva, C Nava, B Ambrosi, G Fagli. Clinical use of pre- and postsurgical evaluation of abnormal GH responses in acromegaly. Journal of neurosurgery. vol 59. issue 3. 1983-10-08. PMID:6411870. |
the reappearance of active acromegaly in the patient with low postoperative gh levels, who was still responsive to trh, should be regarded as a reactivation and not a true recurrence of the disease. |
1983-10-08 |
2023-08-12 |
Not clear |
| J W Nortier, R J Croughs, G H Donker, J H Thijssen, F Schwar. No acute effect of pimozide on the plasma GH levels in acromegaly. Acta endocrinologica. vol 103. issue 4. 1983-10-08. PMID:6613492. |
no acute effect of pimozide on the plasma gh levels in acromegaly. |
1983-10-08 |
2023-08-12 |
Not clear |
| J W Nortier, R J Croughs, G H Donker, J H Thijssen, F Schwar. No acute effect of pimozide on the plasma GH levels in acromegaly. Acta endocrinologica. vol 103. issue 4. 1983-10-08. PMID:6613492. |
the present study does not not lend support to the idea that there is a fundamental difference in the degree of hypothalamic dopaminergic control of gh or prl secretion between bromocriptine sensitive and bromocriptine insensitive patients with acromegaly. |
1983-10-08 |
2023-08-12 |
Not clear |
| M W Ashcraft, P I Hartzband, A J Van Herle, N Bersch, D W Gold. A unique growth factor in patients with acromegaloidism. The Journal of clinical endocrinology and metabolism. vol 57. issue 2. 1983-08-26. PMID:6863475. |
acromegaloidism is a syndrome characterized by features of acromegaly without biochemical evidence of excessive gh or somatomedin production. |
1983-08-26 |
2023-08-12 |
human |