| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wanhong Zuo, Liwei Wang, Lixin Chen, Krešimir Krnjević, Rao Fu, Xia Feng, Wen He, Seungwoo Kang, Avi Shah, Alex Bekker, Jiang-Hong Y. Ethanol potentiates both GABAergic and glutamatergic signaling in the lateral habenula. Neuropharmacology. vol 113. issue Pt A. 2017-06-30. PMID:27678415. |
we previously showed that ethanol enhances glutamatergic transmission and stimulates lhb neurons. |
2017-06-30 |
2023-08-13 |
rat |
| Guiqin Xie, Wanhong Zuo, Liangzhi Wu, Wenting Li, Wei Wu, Alex Bekker, Jiang-Hong Y. Serotonin modulates glutamatergic transmission to neurons in the lateral habenula. Scientific reports. vol 6. 2017-02-17. PMID:27033153. |
we compared serotonin's effects on glutamatergic transmission across the lhb in rat brains. |
2017-02-17 |
2023-08-13 |
rat |
| Victor Mathis, Brigitte Cosquer, Martino Avallone, Jean-Christophe Cassel, Lucas Lecourtie. Excitatory Transmission to the Lateral Habenula Is Critical for Encoding and Retrieval of Spatial Memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 12. 2016-08-02. PMID:25971591. |
in the present study, we used two pharmacological approaches-lhb reversible inactivation with intra-lhb infusion of muscimol, an agonist of the gaba-a receptor, or blockade of excitatory inputs with intra-lhb infusion of 6-cyano-7-nitroquinoxaline-2,3-dione (cnqx), an antagonist of the glutamatergic ampa receptor-to investigate the involvement of the lhb in encoding, consolidation, and retrieval of spatial memory in the water maze (wm) in rats. |
2016-08-02 |
2023-08-13 |
rat |
| Victor Mathis, Brigitte Cosquer, Martino Avallone, Jean-Christophe Cassel, Lucas Lecourtie. Excitatory Transmission to the Lateral Habenula Is Critical for Encoding and Retrieval of Spatial Memory. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 40. issue 12. 2016-08-02. PMID:25971591. |
they further suggest a dichotomy between the role of glutamatergic and other inputs to the lhb in hippocampus-dependent memory processing, as well as in emotional aspects of goal-directed behaviors. |
2016-08-02 |
2023-08-13 |
rat |
| Hongbin Yang, Junhua Yang, Wang Xi, Sijia Hao, Benyan Luo, Xiaobin He, Liya Zhu, Huifang Lou, Yan-qin Yu, Fuqiang Xu, Shumin Duan, Hao Wan. Laterodorsal tegmentum interneuron subtypes oppositely regulate olfactory cue-induced innate fear. Nature neuroscience. vol 19. issue 2. 2016-06-03. PMID:26727549. |
finally, activation of lhb glutamatergic inputs to ldt interneurons was sufficient to generate fear-like responses. |
2016-06-03 |
2023-08-13 |
mouse |
| Alice M Stamatakis, Maaike Van Swieten, Marcus L Basiri, Grace A Blair, Pranish Kantak, Garret D Stube. Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758824. |
here, we show that lateral hypothalamic area (lha) glutamatergic neurons, and their projections to the lateral habenula (lhb), negatively regulate the consumption of palatable food. |
2016-05-17 |
2023-08-13 |
mouse |
| Alice M Stamatakis, Maaike Van Swieten, Marcus L Basiri, Grace A Blair, Pranish Kantak, Garret D Stube. Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758824. |
anterior lha glutamatergic neurons send a functional glutamatergic projection to the lhb, a brain region involved in processing aversive stimuli and negative reward prediction outcomes. |
2016-05-17 |
2023-08-13 |
mouse |
| Alice M Stamatakis, Maaike Van Swieten, Marcus L Basiri, Grace A Blair, Pranish Kantak, Garret D Stube. Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758824. |
pathway-specific, optogenetic stimulation of glutamatergic lha-lhb circuit resulted in detectable glutamate-mediated epscs as well as gaba-mediated ipscs, although the net effect of neurotransmitter release was to increase the firing of most lhb neurons. |
2016-05-17 |
2023-08-13 |
mouse |
| Alice M Stamatakis, Maaike Van Swieten, Marcus L Basiri, Grace A Blair, Pranish Kantak, Garret D Stube. Lateral Hypothalamic Area Glutamatergic Neurons and Their Projections to the Lateral Habenula Regulate Feeding and Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 2. 2016-05-17. PMID:26758824. |
collectively, these results demonstrate that lha glutamatergic neurons are well situated to bidirectionally regulate feeding and potentially other behavioral states via their functional circuit connectivity with the lhb and potentially other brain regions. |
2016-05-17 |
2023-08-13 |
mouse |
| Philip Jean-Richard Dit Bressel, Gavan P McNall. The role of the lateral habenula in punishment. PloS one. vol 9. issue 11. 2015-08-18. PMID:25365401. |
the lhb is known to modulate midbrain dopamine (da) neurons, including inhibition of ventral tegmental area (vta) neurons via glutamatergic excitation of the gabaergic rostromedial tegmental nucleus (rmtg). |
2015-08-18 |
2023-08-13 |
rat |
| Frank J Meye, Kristina Valentinova, Salvatore Lecca, Lucile Marion-Poll, Matthieu J Maroteaux, Stefano Musardo, Imane Moutkine, Fabrizio Gardoni, Richard L Huganir, François Georges, Manuel Mamel. Cocaine-evoked negative symptoms require AMPA receptor trafficking in the lateral habenula. Nature neuroscience. vol 18. issue 3. 2015-04-20. PMID:25643299. |
we found that, in mouse lateral habenula (lhb) neurons targeting the rostromedial tegmental nucleus, cocaine enhanced glutamatergic transmission, reduced k(+) currents and increased excitability. |
2015-04-20 |
2023-08-13 |
mouse |
| David H Root, Carlos A Mejias-Aponte, Jia Qi, Marisela Morale. Role of glutamatergic projections from ventral tegmental area to lateral habenula in aversive conditioning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 42. 2015-02-06. PMID:25319687. |
we conclude that there is a glutamatergic signal from vta vglut2-mesohabenular neurons that plays a role in aversion by activating lhb glutamatergic receptors. |
2015-02-06 |
2023-08-13 |
mouse |
| Eun-Kyung Hwang, Jun-mo Chun. 5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. Neuropharmacology. vol 81. 2014-12-15. PMID:24508708. |
despite the potential importance of glutamatergic excitatory synapses in depression-like behavior, modulation of these lhb synapses by monoamines such as serotonin (5ht) is not fully understood at the cellular and molecular level. |
2014-12-15 |
2023-08-12 |
rat |
| Eun-Kyung Hwang, Jun-mo Chun. 5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. Neuropharmacology. vol 81. 2014-12-15. PMID:24508708. |
therefore, we used whole cell voltage-clamp recording to examine the molecular mechanisms by which 5ht modulates glutamatergic transmission in the lhb. |
2014-12-15 |
2023-08-12 |
rat |
| Eun-Kyung Hwang, Jun-mo Chun. 5HT(1B) receptor-mediated pre-synaptic depression of excitatory inputs to the rat lateral habenula. Neuropharmacology. vol 81. 2014-12-15. PMID:24508708. |
the present study provides the first evidence that glutamatergic transmission of lhb synapses is inhibited by activation of the 5ht(1b) receptor at the pre-synapse in both acute depression (5ht-ad) and long-term depression (5ht-ltd). |
2014-12-15 |
2023-08-12 |
rat |
| Wolfram C Poller, Vince I Madai, René Bernard, Gregor Laube, Rüdiger W Ve. A glutamatergic projection from the lateral hypothalamus targets VTA-projecting neurons in the lateral habenula of the rat. Brain research. vol 1507. 2014-09-18. PMID:23348378. |
these experiments revealed a mainly glutamatergic projection, probably exerting excitatory effects on the targeted lhb cells. |
2014-09-18 |
2023-08-12 |
rat |
| Wolfram C Poller, Vince I Madai, René Bernard, Gregor Laube, Rüdiger W Ve. A glutamatergic projection from the lateral hypothalamus targets VTA-projecting neurons in the lateral habenula of the rat. Brain research. vol 1507. 2014-09-18. PMID:23348378. |
taken together, the present study describes a strong mainly glutamatergic projection from the lha that targets vta/rmtg-projecting neurons in the lhb. |
2014-09-18 |
2023-08-12 |
rat |
| Cameron H Good, Huikun Wang, Yuan-Hao Chen, Carlos A Mejias-Aponte, Alexander F Hoffman, Carl R Lupic. Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 43. 2013-12-23. PMID:24155292. |
glutamatergic lateral habenula (lhb) output communicates negative motivational valence to ventral tegmental area (vta) dopamine (da) neurons via activation of the rostromedial tegmental nucleus (rmtg). |
2013-12-23 |
2023-08-12 |
rat |
| Cameron H Good, Huikun Wang, Yuan-Hao Chen, Carlos A Mejias-Aponte, Alexander F Hoffman, Carl R Lupic. Dopamine D4 receptor excitation of lateral habenula neurons via multiple cellular mechanisms. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 43. 2013-12-23. PMID:24155292. |
these results demonstrate that da can excite glutamatergic lhb output to rmtg via multiple cellular mechanisms. |
2013-12-23 |
2023-08-12 |
rat |
| Hidenori Aizawa, Megumi Kobayashi, Sayaka Tanaka, Tomoki Fukai, Hitoshi Okamot. Molecular characterization of the subnuclei in rat habenula. The Journal of comparative neurology. vol 520. issue 18. 2013-04-18. PMID:22700183. |
in contrast, neurons in the lateral habenula (lhb) were almost uniformly glutamatergic. |
2013-04-18 |
2023-08-12 |
rat |