| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Luciano Gonçalves, Chemutai Sego, Martin Metzge. Differential projections from the lateral habenula to the rostromedial tegmental nucleus and ventral tegmental area in the rat. The Journal of comparative neurology. vol 520. issue 6. 2012-12-14. PMID:22020635. |
the rmtg receives glutamatergic inputs from the lateral habenula (lhb) and sends substantial gabaergic projections to the vta, which also receives direct projections from the lhb. |
2012-12-14 |
2023-08-12 |
rat |
| Matthieu Maroteaux, Manuel Mamel. Cocaine evokes projection-specific synaptic plasticity of lateral habenula neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 36. 2012-11-16. PMID:22956853. |
recent evidence demonstrates that ampa receptors lacking the glua2 subunit mediate glutamatergic transmission in lhb neurons. |
2012-11-16 |
2023-08-12 |
mouse |
| Steven J Shabel, Christophe D Proulx, Anthony Trias, Ryan T Murphy, Roberto Malino. Input to the lateral habenula from the basal ganglia is excitatory, aversive, and suppressed by serotonin. Neuron. vol 74. issue 3. 2012-07-12. PMID:22578499. |
although the output of the basal ganglia is thought to be primarily inhibitory, here we show that transmission from the basal ganglia to the lhb is excitatory, glutamatergic, and suppressed by serotonin. |
2012-07-12 |
2023-08-12 |
Not clear |
| W C Poller, R Bernard, C Derst, T Weiss, V I Madai, R W Ve. Lateral habenular neurons projecting to reward-processing monoaminergic nuclei express hyperpolarization-activated cyclic nucleotid-gated cation channels. Neuroscience. vol 193. 2012-01-18. PMID:21798320. |
glutamatergic lhb efferents terminate on gabaergic neurons in the vta, the rostromedial tegmental nucleus (rmtg), and the raphe nuclei, thereby suppressing monoamine release when required by the present behavioral context. |
2012-01-18 |
2023-08-12 |
rat |
| Simon Hong, Thomas C Jhou, Mitchell Smith, Kadharbatcha S Saleem, Okihide Hikosak. Negative reward signals from the lateral habenula to dopamine neurons are mediated by rostromedial tegmental nucleus in primates. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 32. 2011-10-04. PMID:21832176. |
yet lhb neurons are largely glutamatergic, indicating that this inhibition may occur through an intermediate structure. |
2011-10-04 |
2023-08-12 |
rat |
| K Brinschwitz, A Dittgen, V I Madai, R Lommel, S Geisler, R W Ve. Glutamatergic axons from the lateral habenula mainly terminate on GABAergic neurons of the ventral midbrain. Neuroscience. vol 168. issue 2. 2010-08-19. PMID:20353812. |
here we show, using in situ hybridization and immunocytochemical double labeling at the light and electron microscopic level, that gabaergic neurons are scarce in the lhb and that glutamatergic axons from the lhb mostly target gabaergic neurons in the vta and the mesopontine rostromedial tegmental nucleus (rmtg), also known as tail of the vta (tvta). |
2010-08-19 |
2023-08-12 |
Not clear |
| Natalia Omelchenko, Roland Bell, Susan R Sesac. Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19788571. |
as lhb efferents are reportedly glutamatergic, their ability to inhibit da cells would theoretically require a disynaptic connection involving vta gaba neurons and their local collateral inputs to da cells. |
2010-01-18 |
2023-08-12 |
rat |
| Natalia Omelchenko, Roland Bell, Susan R Sesac. Lateral habenula projections to dopamine and GABA neurons in the rat ventral tegmental area. The European journal of neuroscience. vol 30. issue 7. 2010-01-18. PMID:19788571. |
pre-embedding immunogold labeling for the vesicular glutamate transporter type 2 and post-embedding immunogold staining for gaba confirmed that approximately 85% of lhb terminals were glutamatergic and not gabaergic. |
2010-01-18 |
2023-08-12 |
rat |